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Agreement between Myocardial Infarction Patients and Their Spouses on Reporting of Data on 82 Cardiovascular Risk Exposures
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine.
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2015 (English)In: PLoS ONE, ISSN 1932-6203, Vol. 10, no 7, e0132601Article in journal (Refereed) Published
Abstract [en]

Background The validity of exposure data collected from proxy respondents of myocardial infarction patients has scarcely been studied. We assessed the level of disagreement between myocardial infarction patients and their spouses with respect to the reporting of the patient's cardiovascular risk exposures. Methods Within the frame of the Stockholm Heart Epidemiology Program (SHEEP), a case-control study of risk factors of myocardial infarction performed in Stockholm county 1992-1994, a subset of 327 first time myocardial infarction cases aged 45-70 who survived >28 days after the event and who co-habited with a spouse or common-law spouse (proxy) were identified between 1993-04-05 and 1993-12-31. Among these, 243 cases participated along with their respective proxy in the present study. Control individuals, matched to cases by age, sex and residential area were also included (n = 243). Data were collected using questionnaires. Using conditional logistic regression we calculated for each of 82 exposures the odds ratio based on information collected from 1) myocardial infarction cases and controls [odds ratio A] and 2) proxies and the same set of controls [odds ratio B]. Disagreement was measured by calculating the ratio between odds ratio B and odds ratio A with 95% confidence intervals (CI) calculated using resampling bootstrap. Results For the vast majority of the exposures considered including diet, smoking, education, work-related stress, and family history of CVD, there was no statistically significant disagreement between myocardial infarction patients and proxies (n = 243 pairs). However, leisure time physical inactivity (proxy bias = 1.59, 95% CI 1.05-3.57) was overestimated by spouses compared to myocardial infarction patients. A few other exposures including some sleep-related problems and work-related issues also showed disagreement. Conclusions Myocardial infarction patients and their spouses similarly reported data on a wide range of exposures including the majority of the traditional cardiovascular risk factors, leisure time physical inactivity being an exception.

Place, publisher, year, edition, pages
2015. Vol. 10, no 7, e0132601
National Category
Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:uu:diva-260629DOI: 10.1371/journal.pone.0132601ISI: 000358162300157PubMedID: 26161850OAI: oai:DiVA.org:uu-260629DiVA: diva2:847877

This study was supported by grants from the Swedish Council for Work Life and Social Research (http://www.forte.se/en/) and the Stockholm County Council (http://www.sll.se/om-landstinget/Information-in-English1/). In addition, a grant from the ERACOL (http://erasmus-columbus.eu/about/) an Erasmus Mundus Target 2 program, was awarded to HKQ.

Available from: 2015-08-21 Created: 2015-08-21 Last updated: 2015-08-21Bibliographically approved

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