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Atypical focal non-neoplastic brain changes in neurofibromatosis type 1: mass effect and contrast enhancement
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology. (RAD)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health. (Barnneurologisk forskning/Ahlsten)
2001 (English)In: Neuroradiology, ISSN 0028-3940, E-ISSN 1432-1920, Vol. 43, no 7, 586-90 p.Article in journal (Refereed) Published
Abstract [en]

Children and young adults with neurofibromatosis type 1 often have small high-signal foci on T2-weighted images of the brain. We describe follow-up of two patients in whom one of the foci had atypical features, commonly regarded as signs of a neoplasm. In the first, one lesion showed temporary contrast enhancement and decreasing mass effect. The second developed an expanding lesion that increased minimally in size over 4.5 year's follow-up. The borderline between neoplastic and non-neoplastic lesions seems to be indistinct.

Place, publisher, year, edition, pages
2001. Vol. 43, no 7, 586-90 p.
Keyword [en]
Neurofibromatosis, Brain tumours, Magnetic resonance imaging
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-57348DOI: 10.1007/s002340100556PubMedID: 11512593OAI: oai:DiVA.org:uu-57348DiVA: diva2:85257
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2017-12-04Bibliographically approved

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