uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Failure location predictoin by finite element analysis for an additive manufactured mandible implant
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Mechanics.
Department of Oral and Maxillofacial Surgery, Skåne University Hospital.
Sports Tech Research Centre, Mid Sweden University.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Oral and Maxillofacial Surgery.
Show others and affiliations
2015 (English)In: Medical Engineering and Physics, ISSN 1350-4533, E-ISSN 1873-4030, Vol. 37, no 9, 862-869 p.Article in journal (Refereed) Published
Abstract [en]

In order to reconstruct a patient with a bone defect in the mandible, a porous scaffold attached to a plate, both in a titanium alloy, was designed and manufactured using additive manufacturing. Regrettably, the implant fractured in vivo several months after surgery. The aim of this study was to investigate the failure of the implant and show a way of predicting the mechanical properties of the implant before surgery. All computed tomography data of the patient were preprocessed to remove metallic artefacts with metal deletion technique before mandible geometry reconstruction. The three-dimensional geometry of the patient's mandible was also reconstructed, and the implant was fixed to the bone model with screws in Mimics medical imaging software. A finite element model was established from the assembly of the mandible and the implant to study stresses developed during mastication. The stress distribution in the load-bearing plate was computed, and the location of main stress concentration in the plate was determined. Comparison between the fracture region and the location of the stress concentration shows that finite element analysis could serve as a tool for optimizing the design of mandible implants.

Place, publisher, year, edition, pages
2015. Vol. 37, no 9, 862-869 p.
National Category
Applied Mechanics
URN: urn:nbn:se:uu:diva-262683DOI: 10.1016/j.medengphy.2015.06.001ISI: 000361409100005OAI: oai:DiVA.org:uu-262683DiVA: diva2:854849
Available from: 2015-09-18 Created: 2015-09-18 Last updated: 2016-10-06Bibliographically approved
In thesis
1. Biomechanical Analysis of Stress and Stiffness of New Load-Bearing Implants
Open this publication in new window or tab >>Biomechanical Analysis of Stress and Stiffness of New Load-Bearing Implants
2015 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Medical implants are essential products for saving lives and improving life quality. Nowadays, the demand for implants, especially biocompatible and personalized ones, is increasing rapidly to deal with factors like congenital malformations, aging, and increasing prevalence of cancer. To facilitate their clinical applications, better understanding of their biomechanical properties is important. This thesis focuses on tubular and mandibular implants, and aims at studying stiffness properties and assessing stress distributions.

Tubular implants with coupled helical-coil structure, which can be potentially used as tubular organ constructs, were manufactured by winding polycaprolactone filaments. Tensile and bending stiffnesses were evaluated through mechanical testing and finite element simulations. By increasing the number of helical coils, we could realize a new type of tubular implants which could be used in applications like trachea and urethra stents. Stiffness properties of such implants were investigated analytically, due to the geometrical periodicity. Through computational homogenization, the discrete mesh structures were converted to equivalent continua, whose structural properties were studied using composite beam theories. The numerical and analytical models developed can serve as tools for the mechanical design of implants.

A patient-specific mandibular implant, additively manufactured of titanium alloys, failed shortly after surgery. The failure was studied using a numerical approach. Finite element models were generated from the 3D bone reconstructed from computed tomography data and implants processed by computational homogenization. The failure location and that of the numerically predicted largest von Mises stress agree well, which confirms the feasibility of using finite element simulations to quantitatively analyze implant failures and assist in implants design.

For implant failures caused by local bone loss, analytical studies were also carried out to assess the stress distribution around screw-loaded holes in bones. The mandibular bone was treated as a laminate of which elastic properties were obtained by classical laminate theory. The stress profiles were predicted using a complex stress function method. The loading direction was found to have a minor influence on the stress distributions, while the friction coefficient has non-negligible influence. The stress state can serve as starting point to predict bone remodeling and be compared with criteria for bone strength.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2015. 61 p.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214 ; 1290
National Category
Applied Mechanics
Research subject
Engineering science with specialization in Applied Mechanics
urn:nbn:se:uu:diva-262688 (URN)978-91-554-9342-4 (ISBN)
Public defence
2015-11-06, Sal 80101, Ångströmlaboratoriet, Lägerhyddsvägen 1, Uppsala, 09:00 (English)
Available from: 2015-10-15 Created: 2015-09-18 Last updated: 2015-10-27

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Huo, JinxingHirsch, Jan-MichaélGamstedt, E. Kristofer
By organisation
Applied MechanicsOral and Maxillofacial Surgery
In the same journal
Medical Engineering and Physics
Applied Mechanics

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 512 hits
ReferencesLink to record
Permanent link

Direct link