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Influence of twist on vein and PTFE graft hemodynamics: an ex vivo experimental study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. (Vascular Surgery)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. (Vascular Surgery)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. (Vascular Surgery)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. (Vascular Surgery)
1997 (English)In: Panminerva Medica (Testo stampato), ISSN 0031-0808, E-ISSN 1827-1898, Vol. 39, no 2, 95-99 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: In an ex vivo infusion model, the effect of different factors affecting the critical level of twist in vein and PTFE grafts was analysed.

SETTING: University Hospital, Department of Surgery.

EXPERIMENTAL DESIGN: Saline perfusion of grafts with various diameter and length under constant high (90 ml/min) and low (50 ml/min) flow rates against various peripheral resistance was performed.

MEASURES: The pressure changes in the grafts were measured at increasing increments of twisting.

RESULTS: The critical level of twist appears to be dependent on the diameter, length, stretching, status of peripheral resistance, amount of volume flow and the type of graft material, varying between 90 to more than 360 degrees. In vein grafts critical twisting appeared earlier with a decrease in diameter, shortening in length, high peripheral resistance, high flow rate and stretching. PTFE grafts especially with external spiral support were resistant to twist.

CONCLUSIONS: These data suggest that the critical level of graft twist is dependent upon multiple factors and moderate or even high grade twist with especially externally supported PTFE grafts regardless of length and long mobilized vein grafts do not lead to hemodynamic changes. On the other hand total cessation of flow occurs at lower degrees of twist in stretched, short vein grafts.

Place, publisher, year, edition, pages
1997. Vol. 39, no 2, 95-99 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-58042PubMedID: 9230617OAI: oai:DiVA.org:uu-58042DiVA: diva2:85951
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2017-12-01Bibliographically approved

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