uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Complement activation by polymethyl methacrylate minimized by end-point heparin attachment.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
Show others and affiliations
1993 (English)In: Biomaterials, ISSN 0142-9612, E-ISSN 1878-5905, Vol. 14, no 3, 189-192 p.Article in journal (Refereed) Published
Abstract [en]

After intraocular lens implantation, despite good clinical results, many cataract patients develop a chronic uveitis, caused by an inflammatory response to the implant. One way to improve the biocompatibility of the intraocular lens is to modify the surface by end-point heparin attachment. This study shows that complement activation caused by poly(methyl methacrylate) can be diminished by end-point heparin attachment, as demonstrated by a significant reduction in the generation of C3a and fluid phase terminal complement complexes. It suggests that assessment of complement activation is a good indicator of the biocompatibility of intraocular lenses.

Place, publisher, year, edition, pages
1993. Vol. 14, no 3, 189-192 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-265473PubMedID: 8476991OAI: oai:DiVA.org:uu-265473DiVA: diva2:865789
Available from: 2015-10-29 Created: 2015-10-29 Last updated: 2017-12-01

Open Access in DiVA

No full text

PubMed
By organisation
Department of Oncology, Radiology and Clinical Immunology
In the same journal
Biomaterials
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 269 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf