uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Swedish National Registry of Urinary Bladder Cancer: No difference in relative survival over time despite more aggressive treatment.
Show others and affiliations
2016 (English)In: Scandinavian journal of urology, ISSN 2168-1805, E-ISSN 2168-1813, Vol. 50, no 1, 14-20 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: The aim of this study was to use the Swedish National Registry of Urinary Bladder Cancer (SNRUBC) to investigate changes in patient and tumour characteristics, management and survival in bladder cancer cases over a period of 15 years.

MATERIALS AND METHODS: All patients with newly detected bladder cancer reported to the SNRUBC during 1997-2011 were included in the study. The cohort was divided into three groups, each representing 5 years of the 15 year study period.

RESULTS: The study included 31,266 patients (74% men, 26% women) with a mean age of 72 years. Mean age was 71.7 years in the first subperiod (1997-2001) and 72.5 years in the last subperiod (2007-2011). Clinical T categorization changed from the first to the last subperiod: Ta from 45% to 48%, T1 from 21.6% to 22.4%, and T2-T4 from 27% to 25%. Also from the first to the last subperiod, intravesical treatment after transurethral resection for T1G2 and T1G3 tumours increased from 15% to 40% and from 30% to 50%, respectively, and cystectomy for T2-T4 tumours increased from 30% to 40%. No differences between the analysed subperiods were found regarding relative survival in patients with T1 or T2-T4 tumours, or in the whole cohort.

CONCLUSIONS: This investigation based on a national bladder cancer registry showed that the age of the patients at diagnosis increased, and the proportion of muscle-invasive tumours decreased. The treatment of all tumour stages became more aggressive but relative survival showed no statistically significant change over time.

Place, publisher, year, edition, pages
2016. Vol. 50, no 1, 14-20 p.
Keyword [en]
Bladder cancer; population-based; survival
National Category
Cancer and Oncology Urology and Nephrology
URN: urn:nbn:se:uu:diva-266541DOI: 10.3109/21681805.2015.1085089ISI: 000367832000004PubMedID: 26382667OAI: oai:DiVA.org:uu-266541DiVA: diva2:868319
Available from: 2015-11-10 Created: 2015-11-10 Last updated: 2016-02-09Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Malmström, Per-Uno
By organisation
In the same journal
Scandinavian journal of urology
Cancer and OncologyUrology and Nephrology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 104 hits
ReferencesLink to record
Permanent link

Direct link