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Cancer Characteristics and Current Treatments of Patients with Renal Cell Carcinoma in Sweden
Umea Univ, Dept Surg & Perioperat Sci, Urol & Androl, S-90187 Umea, Sweden.;Karolinska Inst, Urol Sect, Dept Mol Med & Surg, S-17176 Stockholm, Sweden.;Univ Oxford, Nuffield Dept Surg Sci, Surg Intervent Trials Unit, Oxford OX3 7DQ, England..
Karolinska Univ Hosp, Dept Oncol, S-17176 Stockholm, Sweden..
Univ Orebro, Fac Med & Hlth, Dept Urol, S-70182 Orebro, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Urology. Akad Univ Hosp, Dept Urol, S-75185 Uppsala, Sweden..
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2015 (English)In: BioMed Research International, ISSN 2314-6133, E-ISSN 2314-6141, 456040Article in journal (Refereed) Published
Abstract [en]

Methodology. Since the start in 2005 virtually all patients with newly diagnosed renal cell carcinoma (RCC) in Sweden are reported to the National Swedish Kidney Cancer Register (NSKCR). The register contains information on histopathology, nuclear grade, clinical stage, preoperative work-up, treatment, recurrence, and survival. Results. A total of 8556 patients with newly diagnosed RCC were registered in the NSKCR from 2005 to 2013 resulting in a coverage of 99% as compared to the Swedish Cancer Registry. The mean tumor size at detection decreased from 70 mm in 2005 to 64 mm in 2010. The proportion of patients who were incidentally detected increased. The proportion of patients with tumor stage T1a who underwent partial nephrectomy increased from 22% in 2005 to 56% in 2012. Similarly, the proportion of laparoscopically performed radical nephrectomies increased from 6% in 2005 to 17% in 2010. During the five years of follow-up 20% of the patients had a recurrence. Conclusion. Over the last decade there has been a trend of earlier detection and less advanced tumors at detection in patients with RCC. An increasing proportion of the patients undergo laparoscopic and nephron-sparing procedures.

Place, publisher, year, edition, pages
2015. 456040
National Category
Cancer and Oncology
URN: urn:nbn:se:uu:diva-267353DOI: 10.1155/2015/456040ISI: 000363574700001OAI: oai:DiVA.org:uu-267353DiVA: diva2:872792
Available from: 2015-11-20 Created: 2015-11-20 Last updated: 2015-11-20Bibliographically approved

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