Synthesis and characterization of photoswitchable stiff-stilbene based amino acid derivatives
(English)Manuscript (preprint) (Other academic)
Synthetic routes towards the Boc-protected amino acids 1 and 2 incorporating the stiff stilbene chromophore via the corresponding indanone carboxylic acids have been devised. Crucial steps are a reductive McMurry coupling of the indanone carboxylic acids, yielding stiff stilbene dicarboxylic acid esters. Hydrolysis to the monoester and conversion to the azides, followed by a Curtius rearrangement afforded the Boc-protected amino acid ester 1.
Research subject Chemistry with specialization in Organic Chemistry
IdentifiersURN: urn:nbn:se:uu:diva-267829OAI: oai:DiVA.org:uu-267829DiVA: diva2:874514
FunderSwedish Research Council, 621-2012-3379