uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Exploring possible association between DβH genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Child and Adolescent Psychiatry.
Show others and affiliations
2015 (English)In: European Archives of Psychiatry and Clinical Neuroscience, ISSN 0940-1334, E-ISSN 1433-8491Article in journal (Refereed) Epub ahead of print
Abstract [en]

Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.

Place, publisher, year, edition, pages
National Category
URN: urn:nbn:se:uu:diva-268013DOI: 10.1007/s00406-015-0664-3PubMedID: 26616837OAI: oai:DiVA.org:uu-268013DiVA: diva2:875446
Available from: 2015-12-01 Created: 2015-12-01 Last updated: 2016-02-17

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Isaksson, Johan
By organisation
Child and Adolescent Psychiatry
In the same journal
European Archives of Psychiatry and Clinical Neuroscience

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 171 hits
ReferencesLink to record
Permanent link

Direct link