Regenerable thiophenolic radical-trapping antioxidants
2015 (English)In: Organic Letters, ISSN 1523-7060, E-ISSN 1523-7052, Vol. 17, no 24, 6162-6165 p.Article in journal (Refereed) Published
Diphenyl disulfides carrying alkyltelluro groups in the o-, m-, and p-positions were prepared using ortho-lithiation and lithium halogen exchange reactions. The novel antioxidants showed only minimal inhibitory effect on the azo-initiated peroxidation of linoleic acid in chlorobenzene until reduced to the corresponding thiophenols by tris(2-carboxyethyl)phosphine (TCEP). The best in situ generated thiophenol (from 7c) under these conditions quenched peroxyl radicals more efficiently than α-tocopherol with an almost 3-fold increase in inhibition time.
Place, publisher, year, edition, pages
2015. Vol. 17, no 24, 6162-6165 p.
IdentifiersURN: urn:nbn:se:uu:diva-269896DOI: 10.1021/acs.orglett.5b03169ISI: 000366878300057OAI: oai:DiVA.org:uu-269896DiVA: diva2:885408
FunderSwedish Research Council, 621-2011-4006Carl Tryggers foundation , CTS:120