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RCT pilot - Effects of clinical pharmacists at hospital wards
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences, Division of Pharmacokinetics and Drug Therapy.
2016 (English)Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Introduction: Many elderly receive multiple medication treatments, with a risk of drug-related problems. Clinical pharmacist services, such as the performance of medication reviews at hospital wards, can reduce these drug-related problems. Currently a multicentre randomised controlled trial (RCT) is being planned to optimise these clinical services and study the effects after implementation in daily practice.

Aim: To study the feasibility of the planned RCT within a pilot phase, and to propose solutions to encountered problems during this phase in order to improve the methodological quality of the RCT.

Materials and Methods: Prospective RCT pilot study at three hospital wards at Uppsala University Hospital during nearly seven weeks. Patients aged 65 years or older were randomised into two different intervention groups and one control group. Clinical pharmacists performed different activities on the patients. The feasibility was studied and any problems that arose during the pilot study were evaluated.

Results: Informative documents and standard operating procedures (SOPs) were successfully developed and refined. In total 136 out of 186 patients (73.1%) gave consent to participate. Eventually only 52.2% of the included patients received all predefined treatment activities, mainly due to a lack of pharmacist resources and concordance with other ward staff. All encountered problems were solved and/or suggestions for solutions were made, although it was not possible to develop a reliable method to assess drug-related hospital admissions within the time frame of this study.

Conclusions: It is feasible to conduct the planned RCT. However, some issues need to be improved before starting the study, such as the involvement of and concordance with other healthcare professionals and the availability of clinical pharmacists at the wards.

Place, publisher, year, edition, pages
2016. , 31 p.
Keyword [en]
RCT, pilot, effects, clinical pharmacists, hospital
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-273780OAI: oai:DiVA.org:uu-273780DiVA: diva2:895131
External cooperation
Akademiska sjukhuset i Uppsala
Subject / course
Educational program
Master of Science Programme in Pharmacy
Available from: 2016-01-19 Created: 2016-01-18 Last updated: 2016-01-19Bibliographically approved

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