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Effects of chemical exposure on the reproductive ability of Xenopus tropicalis
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
2016 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

During the last decades the amphibian population has been greatly reduced. In many cases the reasons for this reduction is unknown but contamination of the living environment of amphibians may be one of the causing factors. Environmental contamination has been shown to interfere with the functions of the amphibian endocrine system, lead to reduced fertility and overall reproductive disorder. The aim of this study is to investigate the effects of an herbicide and pharmaceutical drug on the reproductive ability in the amphibian Xenopus tropicalis.

Four exposure groups of frogs were mated with unexposed frogs. The number of fertilized eggs was scored by image analysis.

The study revealed that the frogs given the low dose of the herbicide as well as the pharmaceutical drug had a reduced fertility rate compared to the negative control. Very few studies have been made that look into the long-term effects of environmental contaminant exposure of amphibians. These studies are important for the future health of the amphibian population. 

Place, publisher, year, edition, pages
2016. , 25 p.
National Category
Other Natural Sciences
URN: urn:nbn:se:uu:diva-274242OAI: oai:DiVA.org:uu-274242DiVA: diva2:896140
Subject / course
Educational program
Master of Science Programme in Pharmacy
Available from: 2016-10-06 Created: 2016-01-20 Last updated: 2016-10-06Bibliographically approved

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