uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Brushite foamsthe effect of Tween (R) 80 and Pluronic (R) F-127 on foam porosity and mechanical properties
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Tech Univ Catalonia UPC, Dept Mat Sci & Met, Biomat Biomech & Tissue Engn Grp, ETSEIB, Barcelona, Spain.;Biomed Res Networking Ctr Bioengn Biomat & Nanome, Vitoria, Spain..
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Tech Univ Catalonia UPC, Dept Mat Sci & Met, Biomat Biomech & Tissue Engn Grp, ETSEIB, Barcelona, Spain.;Biomed Res Networking Ctr Bioengn Biomat & Nanome, Vitoria, Spain..
Show others and affiliations
2016 (English)In: Journal of Biomedical Materials Research. Part B - Applied biomaterials, ISSN 1552-4973, E-ISSN 1552-4981, Vol. 104, no 1, 67-77 p.Article in journal (Refereed) Published
Resource type
Text
Abstract [en]

Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 -300 mu m has been shown to increase the resorption rate of the implant and speed up bone ingrowth. In this work, macroporous brushite cements were fabricated through foaming of the cement paste, using two different synthetic surfactants, Tween (R) 80 and Pluronic (R) F-127. The macropores formed in the Pluronic samples were both smaller and less homogeneously distributed compared with the pores formed in the Tween samples. The porosity and compressive strength (CS) were comparable to previously developed hydroxyapatite foams. The cement foam containing Tween, 0.5M citric acid in the liquid, 1 mass% of disodium dihydrogen pyrophosphate mixed in the powder and a liquid to powder ratio of 0.43 mL/g, showed the highest porosity values (76% total and 56% macroporosity), while the CS was >1 MPa, that is, the hardened cement could be handled without rupture of the foamed structure. The investigated brushite foams show potential for future clinical use, both as bone void fillers and as scaffolds for in vitro bone regeneration.

Place, publisher, year, edition, pages
2016. Vol. 104, no 1, 67-77 p.
Keyword [en]
Brushite, foam, Tween (R), 80, Pluronic (R), F-127, porosity, strength, setting time
National Category
Materials Engineering
Identifiers
URN: urn:nbn:se:uu:diva-274911DOI: 10.1002/jbm.b.33355ISI: 000367340000009PubMedID: 25615405OAI: oai:DiVA.org:uu-274911DiVA: diva2:898259
Funder
EU, FP7, Seventh Framework ProgrammeThe Swedish Foundation for International Cooperation in Research and Higher Education (STINT), GA IG2011-2047Swedish Research Council, GA 621-2011-6258Swedish Research Council, GA 621-2011-3399
Available from: 2016-01-27 Created: 2016-01-26 Last updated: 2017-11-30Bibliographically approved

Open Access in DiVA

fulltext(1104 kB)204 downloads
File information
File name FULLTEXT01.pdfFile size 1104 kBChecksum SHA-512
addd71c94d84a0593e049310c1438c19a1f19603218b8253cf9b5d01b033cba753f6c115648e895ade9fa14f895a0907d664f78cfa8e7aaa3f925fe72c0865a7
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Unosson, JohannaEngqvist, HåkanPersson, Cecilia

Search in DiVA

By author/editor
Unosson, JohannaEngqvist, HåkanPersson, Cecilia
By organisation
Applied Materials Sciences
In the same journal
Journal of Biomedical Materials Research. Part B - Applied biomaterials
Materials Engineering

Search outside of DiVA

GoogleGoogle Scholar
Total: 204 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 722 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf