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Visual functioning and health-related quality of life in diabetic patients about to undergo anti-vascular endothelial growth factor treatment for sight-threatening macular edema
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. Dalarna Univ, Sch Educ Hlth & Social Studies, Falun, Sweden..
Dalarna Univ, Sch Educ Hlth & Social Studies, Falun, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical diabetology and metabolism.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.
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2015 (English)In: Journal of diabetes and its complications, ISSN 1056-8727, E-ISSN 1873-460X, Vol. 29, no 8, 1183-1190 p.Article in journal (Refereed) Published
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Abstract [en]

Purpose: To examine patient-reported outcome (PRO) in a selected group of Swedish patients about to receive anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME). Material and methods: In this cross-sectional study, 59 patients with diabetes mellitus, who regularly visited the outpatient eye-clinics, were included. Sociodemographic and clinical data were collected and the patients completed PRO measures before starting anti-VEGF treatment. PRO measures assessed eye-specific outcomes (NEI-VFQ-25) and generic health-related quality of life (SF-36). Results: The participants consisted of 30 men and 29 women (mean age, 68.5 years); 54 (92%) patients had type 2 diabetes; 5 (9%) patients had moderate or severe visual impairment; 28 (47%) were classified as having mild visual impairment. Some of the patients reported overall problems in their daily lives, such as with social relationships, as well as problems with impaired sight as a result of reduced distance vision. Conclusions: Further studies are needed to investigate PRO factors related to low perceived general health in this patient population. It is important to increase our understanding of such underlying mechanisms to promote improvements in the quality of patient care.

Place, publisher, year, edition, pages
2015. Vol. 29, no 8, 1183-1190 p.
Keyword [en]
Patient-reported measurements, Health-related quality of life, Visual function, Diabetic macula edema, Anti-VEGF treatment
National Category
Endocrinology and Diabetes
Identifiers
URN: urn:nbn:se:uu:diva-274708DOI: 10.1016/j.jdiacomp.2015.07.026ISI: 000366884900036PubMedID: 26318959OAI: oai:DiVA.org:uu-274708DiVA: diva2:899659
Funder
Magnus Bergvall Foundation
Available from: 2016-02-02 Created: 2016-01-25 Last updated: 2017-11-30Bibliographically approved

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Granström, ThereseLeksell, JanethGranstam, Elisabet

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Granström, ThereseLeksell, JanethGranstam, Elisabet
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Department of Medical SciencesClinical diabetology and metabolismCentre for Clinical Research, County of Västmanland
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Journal of diabetes and its complications
Endocrinology and Diabetes

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