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Cardiac risk in the treatment of breast cancer: assessment and management
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Experimental and Clinical Oncology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland. Vastmanlands Cty Hosp, Ctr Clin Res, Vasteras, Sweden..
2015 (English)In: Breast Cancer: Targets and Therapy, ISSN 1179-1314, E-ISSN 1179-1314, Vol. 7, 21-35 p.Article, review/survey (Refereed) PublishedText
Abstract [en]

As the number of long-term breast cancer survivors has increased, the side effects of adjuvant cancer therapy, such as cardiac toxicity, remain clinically important. Although the cardiac toxicity due to anthracyclines, radiotherapy, or trastuzumab is well-documented, several issues need to be clarified and are the subjects of extensive ongoing clinical research. This review summarizes the incidence of cardiac toxicity due to breast cancer adjuvant therapy and highlights the current trends in early detection and management of cardiac toxicities.

Place, publisher, year, edition, pages
2015. Vol. 7, 21-35 p.
Keyword [en]
adjuvant, anthracyclines, cardiac toxicity, radiotherapy, trastuzumab
National Category
Cancer and Oncology Cardiac and Cardiovascular Systems
URN: urn:nbn:se:uu:diva-276111DOI: 10.2147/BCTT.S47227ISI: 000366124300001PubMedID: 25653554OAI: oai:DiVA.org:uu-276111DiVA: diva2:901902
Available from: 2016-02-09 Created: 2016-02-09 Last updated: 2016-03-30Bibliographically approved

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Valachis, Antonis
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Experimental and Clinical OncologyCentre for Clinical Research, County of Västmanland
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Breast Cancer: Targets and Therapy
Cancer and OncologyCardiac and Cardiovascular Systems

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