uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Increased risk of heart failure in women with symptoms of sleep-disordered breathing
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Cardiology. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, UCR-Uppsala Clinical Research Center.
Show others and affiliations
2016 (English)In: Sleep Medicine, ISSN 1389-9457, E-ISSN 1878-5506, Vol. 17, 32-37 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: An association between obstructive sleep apnea and the incidence of heart failure has been reported in men but not in women. The aim of this study was to investigate whether a combination of snoring and excessive daytime sleepiness, the two main symptoms of obstructive sleep apnea syndrome, was able to predict incident heart failure in a population-based sample of women.

METHODS: The population-based cohort study Sleep and Health in Women (SHE; n = 5990 women born between 1901 and 1980) was used, with baseline questionnaire data from April 2000 relating to snoring, excessive daytime sleepiness, and covariates. Using data retrieved from the Swedish National Patient Register and Cause of Death Register, the follow-up of incident heart failure continued until 31 December 2011.

RESULTS: Among women with both snoring and excessive daytime sleepiness at baseline, 5.3% developed heart failure during follow-up compared with 0.9% in the reference group with neither snoring nor excessive daytime sleepiness. After adjustment for age, waist circumference, smoking, alcohol, hypertension, diabetes, previous myocardial infarction, physical inactivity, depressive symptoms, menopausal status, and hormone replacement therapy, women with the combination of snoring and excessive daytime sleepiness had a twofold increase in the risk of incident heart failure (hazard ratio [HR] 2.2 95% confidence interval [CI] 1.1-4.4).

CONCLUSION: Symptoms of obstructive sleep apnea, that is, the combination of snoring and excessive daytime sleepiness, are associated with an increased risk of developing heart failure in women.

Place, publisher, year, edition, pages
2016. Vol. 17, 32-37 p.
Keyword [en]
Obstructive sleep apnea syndrome; Heart failure; Women; Snoring; Excessive daytime sleepiness
National Category
Medical and Health Sciences Neurology Respiratory Medicine and Allergy
Identifiers
URN: urn:nbn:se:uu:diva-277627DOI: 10.1016/j.sleep.2015.09.018ISI: 000370897100007PubMedID: 26847971OAI: oai:DiVA.org:uu-277627DiVA: diva2:905240
Funder
Swedish Heart Lung Foundation, 19990029Swedish Heart Lung Foundation, 20100494
Available from: 2016-02-22 Created: 2016-02-22 Last updated: 2017-11-30Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Authority records BETA

Ljunggren, MirjamByberg, LiisaTheorell-Haglöw, JennyLindahl, BertilMichaëlsson, KarlLindberg, Eva

Search in DiVA

By author/editor
Ljunggren, MirjamByberg, LiisaTheorell-Haglöw, JennyLindahl, BertilMichaëlsson, KarlLindberg, Eva
By organisation
Department of Medical SciencesOrthopaedicsCardiologyUCR-Uppsala Clinical Research Center
In the same journal
Sleep Medicine
Medical and Health SciencesNeurologyRespiratory Medicine and Allergy

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 335 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf