uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Outcrossing and the maintenance of males within C. elegans populations.
University of Oregon.ORCID iD: 0000-0002-0713-6897
2010 (English)In: Journal of Heredity, ISSN 0022-1503, E-ISSN 1465-7333, Vol. 101 Suppl 1Article in journal (Refereed) Published
Abstract [en]

Caenorhabditis elegans is an androdioecious nematode with both hermaphrodites and males. Although males can potentially play an important role in avoiding inbreeding and facilitating adaptation, their existence is evolutionarily problematic because they do not directly generate offspring in the way that hermaphrodites do. This review explores how genetic, population genomic, and experimental evolution approaches are being used to address the role of males and outcrossing within C. elegans. Although theory suggests that inbreeding depression and male mating ability should be the primary determinants of male frequency, this has yet to be convincingly confirmed experimentally. Genomic analysis of natural populations finds that outcrossing occurs at low, but not negligible levels, and that observed patterns of linkage disequilibrium consistent with strong selfing may instead be generated by natural selection against outcrossed progeny. Recent experimental evolution studies suggest that males can be maintained at fairly high levels if populations are initiated with sufficient genetic variation and/or subjected to strong natural selection via a change in the environment. For example, as reported here, populations adapting to novel laboratory rearing and temperature regimes maintain males at frequencies from 5% to 40%. Laboratory and field results still await full reconciliation, which may be facilitated by identifying the loci underlying among-strain differences in mating system dynamics.

Place, publisher, year, edition, pages
2010. Vol. 101 Suppl 1
National Category
Biological Sciences
URN: urn:nbn:se:uu:diva-277680DOI: 10.1093/jhered/esq003PubMedID: 20212008OAI: oai:DiVA.org:uu-277680DiVA: diva2:905368
Available from: 2016-02-22 Created: 2016-02-22 Last updated: 2016-02-22

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Anderson, Jennifer L
In the same journal
Journal of Heredity
Biological Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 28 hits
ReferencesLink to record
Permanent link

Direct link