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Spontan kranskärls­dissektion kan orsaka akut koronart syndrom: ovanligt tillstånd som kräver genomtänkt handläggning och mer forskning
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, UCR-Uppsala Clinical Research Center.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, UCR-Uppsala Clinical Research Center. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. (kardiologi)
Bild- och funktionsmedicinskt centrum, Akademiska sjukhuset, Uppsala, Sweden.
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2015 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 112, DRFWArticle in journal (Refereed) Published
Abstract [en]

Spontaneous coronary artery dissection (SCAD) is a non-traumatic and non-iatrogenic injury occurring in the vessel wall caused by either a primary intimal dissection or a primary hematoma in the medial layer. SCAD is more common among women than men and accounts for a small minority of acute coronary syndromes. The causes of SCAD are multifactorial. Peripartum SCAD is most common. Fibromuscular dysplasia has a strong association with SCAD. As spontaneous healing is common in SCAD and PCI is associated with complications an initial conservative approach should always be considered. Medical treatment is based on the underlying cause. Beta blockers are recommended to all patients. The prognosis varies; the highest mortality is reported among women suffering peripartum SCAD. Quality of life is often affected in SCAD patients and accompanied by a high rate of rehospitalizations. More research which focuses on the underlying causes, optimal treatment and rehabilitation is needed.

Place, publisher, year, edition, pages
2015. Vol. 112, DRFW
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:uu:diva-278526PubMedID: 26625103OAI: oai:DiVA.org:uu-278526DiVA: diva2:906613
Note

Title in English: [Spontaneous coronary artery dissection can cause acute coronary syndrome. Unusual condition that requires thoughtful management and more research]

Available from: 2016-02-24 Created: 2016-02-24 Last updated: 2017-05-10Bibliographically approved

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PubMedhttp://www.lakartidningen.se/Klinik-och-vetenskap/Klinisk-oversikt/2015/11/Spontan-kranskarlsdissektion-kan-orsaka-akut-koronart-syndrom/

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Johnston, NinaSarno, GiovannaVarenhorst, Christoph

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