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Gout and its comorbidities in the total population of Stockholm
Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Family Med, S-14183 Huddinge, Sweden.;Stockholm Cty Council, Acad Primary Healthcare Ctr, Huddinge, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Cardiovascular epidemiology. Uppsala University, Science for Life Laboratory, SciLifeLab. Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Family Med, S-14183 Huddinge, Sweden..
Stockholm Cty Council, Publ Healthcare Serv Comm Adm, SE-10239 Stockholm, Sweden.;Karolinska Inst, Med Management Ctr, Dept Learning Informat Management & Eth, SE-17177 Stockholm, Sweden..
2015 (English)In: Preventive Medicine, ISSN 0091-7435, E-ISSN 1096-0260, Vol. 81, 387-391 p.Article in journal (Refereed) PublishedText
Abstract [en]

Objective. Study of prevalence of gout with concomitant diseases. Methods. Study population included all living persons in Stockholm County, Sweden, on January 1st 2013 (N = 2,124,959). A diagnosis of gout was identified during 2013-2014, with information of diabetes mellitus and insulin resistance, hypertension, chronic heart failure, chronic kidney disease, alcohol abuse, and malignancies. Age-adjusted odds ratios (ORs) with 95% confidence intervals (95% CI) for women and men with gout, using individuals without gout as referents, were calculated. Results. Age-adjusted odds of co-morbidities among individuals with gout vs. those without goutwere: diabetes mellitus and insulin resistance 3.97 (95% CI 3.65-4.31) in women and 1.88 (95% CI 1.78-1.99) in men; hypertension 4.02 (95% CI 3.69-4.37) inwomen and 3.21 (95% CI 3.06-3.37) in men; chronic heart failure 4.72 (95% CI 4.31-5.19) in women and 2.84 (95% CI 2.66-3.04) inmen; chronic kidney disease 2.08 (95% CI 1.50-2.87) in women and 2.39 (95% CI 2.15-2.66) in men; alcohol abuse 8.98 (95% CI 8.15-9.80) in women and 4.38 (95% CI 4.10-4.69) in men; and malignancies 1.32 (95% CI 1.17-1.48) in women and 1.13 (95% CI 1.06-1.21) men. Conclusion. Gout is a warning sign for concomitant diseases, e.g. alcoholism, diabetes, cardiovascular diseases, and cancer. Key messages. 1. A diagnosis of gout was present in 0.3% among women and 0.8% among men in Stockholm County. 2. Among individuals with gout, hypertension, being the most common concomitant disease, was present in 68% among women and 54% among men. 3. Alcohol abuse was the most overrepresented disorder compared to individuals without gout, with odds ratio of 9 among women and 5 among men.

Place, publisher, year, edition, pages
2015. Vol. 81, 387-391 p.
Keyword [en]
Gout, Administrative databases, Gender differences, Age differences, Epidemiology
National Category
Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:uu:diva-277897DOI: 10.1016/j.ypmed.2015.10.003ISI: 000368421300060OAI: oai:DiVA.org:uu-277897DiVA: diva2:906986
Available from: 2016-02-25 Created: 2016-02-23 Last updated: 2016-02-25Bibliographically approved

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Carlsson, Axel C.
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Cardiovascular epidemiologyScience for Life Laboratory, SciLifeLab
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