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Surrogate Markers of Abdominal Aortic Aneurysm Progression
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
James Cook Univ, Coll Med & Dent, Vasc Biol Unit, Queensland Res Ctr Peripheral Vasc Dis, Townsville, Qld 4811, Australia.;Townsville Hosp, Dept Vasc & Endovasc Surg, Townsville, Qld, Australia..
2016 (English)In: Arteriosclerosis, Thrombosis and Vascular Biology, ISSN 1079-5642, E-ISSN 1524-4636, Vol. 36, no 2, 236-244 p.Article in journal (Refereed) Published
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Abstract [en]

The natural course of many abdominal aortic aneurysms (AAA) is to gradually expand and eventually rupture and monitoring the disease progression is essential to their management. In this publication, we review surrogate markers of AAA progression. AAA diameter remains the most widely used and important marker of AAA growth. Standardized reporting of reproducible methods of measuring AAA diameter is essential. Newer imaging assessments, such as volume measurements, biomechanical analyses, and functional and molecular imaging, as well as circulating biomarkers, have potential to add important information about AAA progression. Currently, however, there is insufficient evidence to recommend their routine use in clinical practice.

Place, publisher, year, edition, pages
2016. Vol. 36, no 2, 236-244 p.
Keyword [en]
aortic aneurysm, abdominal, biomarkers, magnetic resonance imaging, molecular imaging, ultrasonography
National Category
Cardiac and Cardiovascular Systems Surgery
Identifiers
URN: urn:nbn:se:uu:diva-279576DOI: 10.1161/ATVBAHA.115.306538ISI: 000369483200008PubMedID: 26715680OAI: oai:DiVA.org:uu-279576DiVA: diva2:908395
Available from: 2016-03-02 Created: 2016-03-02 Last updated: 2017-11-30Bibliographically approved

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Wanhainen, AndersMani, Kevin

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