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Blood lactate is a useful indicator for the Medical Emergency Team
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
2016 (English)In: Critical Care Research and Practice, ISSN 2090-1305, E-ISSN 2090-1313, 5765202Article in journal (Refereed) Published
Abstract [en]

Lactate has been thoroughly studied and found useful for stratification of patients with sepsis, in the Intensive Care Unit, and trauma care. However, little is known about lactate as a risk-stratification marker in the Medical Emergency Team- (MET-) call setting. We aimed to determine whether the arterial blood lactate level at the time of a MET-call is associated with increased 30-day mortality. This is an observational study on a prospectively gathered cohort at a regional secondary referral hospital. All MET-calls during the two-year study period were eligible. Beside blood lactate, age and vital signs were registered at the call. Among the 211 calls included, there were 64 deaths (30.3%). Median lactate concentration at the time of the MET-call was 1.82 mmol/L (IQR 1.16–2.7). We found differences between survivors and nonsurvivors for lactate and oxygen saturation, a trend for age, but no significant correlations between mortality and systolic blood pressure, respiratory rate, and heart rate. As compared to normal lactate (<2.44 mmol/L), OR for 30-day mortality was 3.54 (p < 0.0006) for lactate 2.44–5.0 mmol/L and 4.45 (p < 0.0016) for lactate > 5.0 mmol/L. The present results support that immediate measurement of blood lactate in MET call patients is a useful tool in the judgment of illness severity.

Place, publisher, year, edition, pages
2016. 5765202
National Category
Anesthesiology and Intensive Care
URN: urn:nbn:se:uu:diva-279972DOI: 10.1155/2016/5765202ISI: 000372258000001OAI: oai:DiVA.org:uu-279972DiVA: diva2:909354
Available from: 2016-03-06 Created: 2016-03-06 Last updated: 2016-04-14Bibliographically approved

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