uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Mid-infrared thin-film diamond waveguides combined with tunable quantum cascade lasers for analyzing the secondary structure of proteins
Univ Ulm, Inst Analyt & Bioanalyt Chem, D-89081 Ulm, Germany.
Univ Ulm, Inst Analyt & Bioanalyt Chem, D-89081 Ulm, Germany.
Univ Ulm, Inst Analyt & Bioanalyt Chem, D-89081 Ulm, Germany.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Show others and affiliations
2016 (English)In: Physica Status Solidi (a) applications and materials science, ISSN 1862-6300, E-ISSN 1862-6319, Vol. 213, no 8, 2117-2123 p.Article in journal (Refereed) Published
Abstract [en]

Diamond has excellent optical properties including broadband transmissivity, low self-absorption, and a high refractive index, which have prompted its use for optical sensing applications. Thin-film diamond strip waveguides (DSWGs) combined with tunable quantum cascade lasers (tQCLs) providing an emission wavelength range of 5.78-6.35 mu m (1735-1570 cm(-1)) have been used to obtain mid-infrared (MIR) spectra of proteins, thereby enabling the analysis of their secondary structure via the amide I band. Three different proteins were analyzed, namely bovine serum albumin (BSA), myoglobin, and gamma-globulin. The secondary structure of BSA and myoglobin has a major contribution of a-helices, whereas gamma-globulins are rich in beta-sheet structures, which is reflected in the amide I band. Acomparison of the spectra obtained via the combination of the tQCL and DSWG with spectra obtained using conventional Fourier transform infrared (FTIR) spectroscopy and a commercial diamond attenuated total reflection (ATR) element has been performed. It is shown that the main features evident in FTIR-ATR spectra are also obtained using tQCL-DSWG sensors.

Place, publisher, year, edition, pages
2016. Vol. 213, no 8, 2117-2123 p.
National Category
Other Physics Topics Engineering and Technology
Identifiers
URN: urn:nbn:se:uu:diva-282255DOI: 10.1002/pssa.201600134ISI: 000385223900016OAI: oai:DiVA.org:uu-282255DiVA: diva2:916787
Available from: 2016-04-04 Created: 2016-04-04 Last updated: 2017-11-30Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Vargas Catalan, ErnestoKarlsson, MikaelNikolajeff, FredrikÖsterlund, Lars

Search in DiVA

By author/editor
Vargas Catalan, ErnestoKarlsson, MikaelNikolajeff, FredrikÖsterlund, Lars
By organisation
Applied Materials SciencesSolid State Physics
In the same journal
Physica Status Solidi (a) applications and materials science
Other Physics TopicsEngineering and Technology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 642 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf