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Tillväxt av insulinproducerande betaceller: Kanske en väg att behandla typ 1-diabetes
Department of molecular and cellular biology, Harvard University, Cambridge, USA.
2002 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 99, no 21, 2394-2399 p.Article, review/survey (Other academic) Published
Abstract [en]

Insulin dependent diabetes mellitus (type 1-diabetes) results from a selective destruction of the insulin producing beta cells and a limited capacity of the remaining cells to regenerate in a compensatory manner. Increased knowledge of the factors involved in the regulation of beta-cell growth may lead to new ways of forming beta cells that in combination with selective immunosuppression could be used for treatment of type 1 diabetes. Physiological and pathophysiological conditions that induce beta-cell growth, different factors that have been implicated to regulate these processes and future perspectives concerning treatment of type 1 diabetes by expanding the beta-cell mass is discussed in this review article.

Place, publisher, year, edition, pages
2002. Vol. 99, no 21, 2394-2399 p.
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-64071PubMedID: 12090167OAI: oai:DiVA.org:uu-64071DiVA: diva2:91982
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2017-11-30Bibliographically approved

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Annerén, Cecilia

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