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Signaling via vascular endothelial growth factor receptors.
1999 (English)In: Experimental Cell Research, ISSN 0014-4827, E-ISSN 1090-2422, Vol. 253, no 1Article in journal (Refereed) Published
Abstract [en]

Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1-3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses. The review focuses on the signaling pathways that are initiated from these receptors and the recently identified VEGF coreceptor neuroplilin-1.

Place, publisher, year, edition, pages
1999. Vol. 253, no 1
National Category
Basic Medicine
URN: urn:nbn:se:uu:diva-287177DOI: 10.1006/excr.1999.4707PubMedID: 10579917OAI: oai:DiVA.org:uu-287177DiVA: diva2:922288
Available from: 2016-04-22 Created: 2016-04-22 Last updated: 2016-04-22

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