Rapid microwave-assisted solid phase peptide synthesis
2002 (English)In: Synthesis (Stuttgart), ISSN 0039-7881, E-ISSN 1437-210X, no 11, 1592-1596 p.Article in journal (Refereed) Published
A microwave-assisted, rapid solid phase peptide synthesis procedure is presented. It has been applied to the coupling of sterically hindered Fmoc-protected amino acids yielding di- and tripeptides. Optimized conditions for a variety of coupling reagents are reported. Peptides were obtained rapidly (1.5-20 min) and without racemization.
Place, publisher, year, edition, pages
2002. no 11, 1592-1596 p.
IdentifiersURN: urn:nbn:se:uu:diva-64335DOI: 10.1055/s-2002-33348OAI: oai:DiVA.org:uu-64335DiVA: diva2:92246