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Finding genes for SLE: complex interactions and complex populations
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
2003 (English)In: Journal of Autoimmunity, ISSN 0896-8411, E-ISSN 1095-9157, Vol. 21, no 2, 117 p.117-120 p.Article in journal (Other academic) Published
Abstract [en]

Many years of work, multiplex family collection and endless genotyping finally give fruit. The original aim cannot be lost. The aim is not only to identify mutations involved in susceptibility for systemic lupus erythematosus (SLE) but to elucidate the disease pathogenesis as well. After genetics comes the biology. We review our recent findings on the genetics of lupus, provide possible mechanisms for disease susceptibility and present some facts on the problematic of identifying susceptibility mutations for complex diseases in complex human populations.

Place, publisher, year, edition, pages
2003. Vol. 21, no 2, 117 p.117-120 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-65732DOI: 10.1016/S0896-8411(03)00093-3PubMedID: 12935780OAI: oai:DiVA.org:uu-65732DiVA: diva2:93643
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2017-11-28Bibliographically approved

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