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Unconventional natural sources for future drug discovery
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Medicinal Chemistry, Division of Pharmacognosy.
2004 (English)In: Drug Discovery Today, ISSN 1359-6446, E-ISSN 1878-5832, Vol. 9, no 10, p. 450-458Article, review/survey (Refereed) Published
Abstract [en]

‘There are more things between heaven and earth…’ Despite the progress of science during the past four centuries, Shakespeare's words did not lose their actuality. Knowledge about the etiology of diseases is still limited, and for many life-threatening illnesses no effective treatments exist. Nature always has been a valuable source of drugs and, despite the unprecedented opportunities afforded by medicinal chemistry, continues to deliver lead compounds. Traditionally, research on natural sources was focused on terrestrial plants and microorganisms. More recently, however, organisms of marine origin are also being investigated. Here, the possibilities of unconventional and hardly explored sources are discussed.

Place, publisher, year, edition, pages
2004. Vol. 9, no 10, p. 450-458
Keywords [en]
unexplored natural sources, natural products, lead finding, unconventional natural sources, natural product research, zoopharmacognosy, drug discovery
National Category
Pharmaceutical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-65976DOI: 10.1016/S1359-6446(04)03066-1ISI: 000221394000010PubMedID: 15109950OAI: oai:DiVA.org:uu-65976DiVA, id: diva2:93887
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2018-01-10Bibliographically approved

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