uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Maternal near-miss at university hospitals with cesarean overuse: an incident case-control study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health. (Internationell kvinno- & mödrahälsovård och migration/Essén)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, International Maternal and Child Health (IMCH). (Internationell kvinno- & mödrahälsovård och migration/Essén)
Shahid Beheshti Univ Med Sci, Infertil & Reprod Hlth Res Ctr, Tehran, Iran.
Shahid Beheshti Univ Med Sci, Infertil & Reprod Hlth Res Ctr, Tehran, Iran.
Show others and affiliations
2016 (English)In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 95, no 7, 777-786 p.Article in journal (Refereed) Published
Abstract [en]

INTRODUCTION: Cesarean section (CS) carries a substantial risk of maternal near-miss (MNM) morbidity. This study aimed at determining the frequency, causes, risk factors, and perinatal outcomes of MNM at three university hospitals with a high rate of CS in Tehran, Iran.

MATERIAL AND METHODS: An incident case-control study was conducted from March 2012 to May 2014. The modified WHO near-miss criteria were used to identify cases. A control sample of 1024 women delivering at the study hospitals was recruited to represent the source population. Near-miss ratio, crude and adjusted odds ratios (aORs) with confidence intervals (CI) were assessed.

RESULTS: Among 12 965 live births, 82 mothers developed near-miss morbidities and 12 died. The MNM ratio was 6.3/1000 live births. Severe postpartum hemorrhage (35%, 29/82), severe pre-eclampsia (32%, 26/82), and placenta previa/abnormally invasive placenta (10%, 8/82) were the most frequent causes of MNM. Women with antepartum CS (aOR 7.4, 95%CI 3.7-15.1) and co-morbidity (aOR 2.3, 95%CI 1.4-3.8), uninsured Iranians (aOR 3.4, 95%CI 1.7-7.1) and uninsured Afghans (aOR 4.7, 95%CI 2.4-9.2) had increased risks of near-miss morbidity. Stillbirth and extremely preterm birth were the most prominent adverse perinatal outcomes associated with MNM.

CONCLUSION: Overutilization of CS clearly influenced the causes of MNM. A lack of health insurance had a measurable impact on near-miss morbidity. Tailored interventions for reducing unnecessary CS and unrestricted insurance cover for emergency obstetric care can potentially improve maternal and perinatal outcomes. This article is protected by copyright. All rights reserved.

Place, publisher, year, edition, pages
2016. Vol. 95, no 7, 777-786 p.
Keyword [en]
Maternal near-miss; cesarean section; placenta previa; abnormally invasive placenta; Afghan migrant; health insurance; Iran
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
URN: urn:nbn:se:uu:diva-296830DOI: 10.1111/aogs.12881ISI: 000380358900008PubMedID: 26918866OAI: oai:DiVA.org:uu-296830DiVA: diva2:939962
Available from: 2016-06-20 Created: 2016-06-20 Last updated: 2016-11-23
In thesis
1. Beyond ‘Cesarean Overuse’: Hospital-Based Audits of Obstetric Care and Maternal Near Miss in Tehran, Iran
Open this publication in new window or tab >>Beyond ‘Cesarean Overuse’: Hospital-Based Audits of Obstetric Care and Maternal Near Miss in Tehran, Iran
2016 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

With one in two women delivering surgically, Iran has one of the highest rates of cesarean section (CS) worldwide. CS overuse in low-risk pregnancies potentially exposes women to Maternal Near-Miss (MNM) morbidity with minimal health benefits. This thesis studied obstetric care quality and MNM at hospitals with high rates of CS in Tehran, Iran.

In Study I, we investigated whether audits of CS indications and feedback influenced CS rates at a general hospital. Subsequent to the audit, a 27% reduction in the risk of primary CS was found.

In Study II, characteristics of MNM were investigated at university hospitals between 2012 and 2014. During a 26-month period, 82 MNM cases were identified using the WHO MNM approach. Severe postpartum hemorrhage (35%), severe preeclampsia (32%), and placenta previa including abnormally invasive placenta (10%) were the main three causes of MNM. Iran has a huge influx of migrants from Afghanistan. Women with antepartum CS and those who lacked health insurance, almost all Afghans, had increased risk of MNM.

In Study III, audits examined whether MNM care quality differed between 54 Iranians and 22 Afghans and whether near-miss events were preventable. A majority of MNM cases (62%) arrived at hospital in a moribund state and obstetric care was more suboptimal for Afghans than Iranians (adjusted odds ratio 5.1, 95% confidence interval 1.2–22.6). Moreover, MNM was commonly (71%) potentially preventable and professionals with suboptimal practice were involved in 85% of preventable cases.

In Study IV, a qualitative interview study was conducted to explore care experiences of Afghan MNM survivors. Discrimination, insufficient medical attention, and ineffective counseling were the main experiences. To a lesser extent, poverty and low education were perceived as contributing factors to delays in accessing care.

This thesis emphasizes the importance of high-quality care for preventing undesirable maternal outcomes. The audit method along with interviews was useful to determine quality and equity gaps in care provision. Policymakers and professionals should consider these gaps when structuring programs to reduce adverse maternal outcomes.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2016. 95 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 1280
Keyword
Caesarean section, maternal near miss, clinical audit, care quality, care experience, Afghan migrants, Iran
National Category
Health Care Service and Management, Health Policy and Services and Health Economy Obstetrics, Gynecology and Reproductive Medicine Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Medical Science
Identifiers
urn:nbn:se:uu:diva-308081 (URN)978-91-554-9757-6 (ISBN)
Public defence
2017-01-18, Rosénsalen, Kvinnokliniken, Ing 95-96, Akademiska Sjukhuset, Uppsala, 13:00 (English)
Opponent
Supervisors
Available from: 2016-12-22 Created: 2016-11-23 Last updated: 2016-12-28

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Mohammadi, SoheilaEssén, BirgittaKällestål, Carina
By organisation
Department of Women's and Children's HealthInternational Maternal and Child Health (IMCH)
In the same journal
Acta Obstetricia et Gynecologica Scandinavica
Obstetrics, Gynecology and Reproductive Medicine

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 392 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf