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Pentoxifylline inhibits neointimal formation and stimulates constrictive vascular remodeling after arterial injury
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
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1999 (English)In: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, ISSN 0160-2446, Vol. 34, no 5, 683-689 p.Article in journal (Other scientific) Published
Abstract [en]

Pentoxifylline (PTX) is a phosphodiesterase inhibitor used in the treatment of peripheral vascular disease, and this agent can suppress inflammatory vascular damage. Inflammation has been implicated in vascular lesion formation, and we examined the effect

Place, publisher, year, edition, pages
LIPPINCOTT WILLIAMS & WILKINS , 1999. Vol. 34, no 5, 683-689 p.
Keyword [en]
pentoxifylline; remodeling; neointima; vascular smooth-muscle cell; apoptosis; collagen; SMOOTH-MUSCLE CELLS; RABBIT MODEL; HUMAN ATHEROSCLEROSIS; CORONARY ANGIOPLASTY; BALLOON ANGIOPLASTY; CYCLIC-AMP; PROLIFERATION; RESTENOSIS; APOPTOSIS; COLLAGEN
Identifiers
URN: urn:nbn:se:uu:diva-66587OAI: oai:DiVA.org:uu-66587DiVA: diva2:94498
Note
Addresses: Hansen PR, Rigshosp, Ctr Heart, Dept Cardiol B2142, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. Rigshosp, Dept Med B2142, DK-2100 Copenhagen, Denmark. Rigshosp, Dept Pathol, DK-2100 Copenhagen, Denmark. Biomed Ctr, Dept Med & Phys Chem, UppsalaAvailable from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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