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Anorectic effect of dehydroepiandrosterone combined with dexfenfluramine or thionisoxetine
2001 (English)In: European Journal of Pharmacology, ISSN 0014-2999, E-ISSN 1879-0712, Vol. 419, no 1Article in journal (Refereed) Published
Abstract [en]

Free feeding rats given supplementary 1 h access per day to a palatable dessert test meal were tested for the anorectic effect of dehydroepiandrosterone alone or in combination with either the serotonin releasing agent dexfenfluramine or the norepinephrine uptake inhibitor thionisoxetine (LY 368975). Isobolographic analysis showed that the effect of dehydroepiandrosterone combined with either dexfenfluramine or thionisoxetine was within the range predicted for additivity of action.

Place, publisher, year, edition, pages
2001. Vol. 419, no 1
National Category
Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-298315PubMedID: 11348631OAI: oai:DiVA.org:uu-298315DiVA: diva2:945607
Available from: 2016-07-01 Created: 2016-07-01 Last updated: 2016-08-01Bibliographically approved

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