uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
TGF-beta and the TGF-beta Family: Context-Dependent Roles in Cell and Tissue Physiology
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Ludwig Institute for Cancer Research.
Univ Calif San Francisco, Dept Cell & Tissue Biol, San Francisco, CA 94143 USA..
Univ Tokyo, Grad Sch Med, Dept Mol Pathol, Bunkyo Ku, Tokyo 1130033, Japan..
2016 (English)In: Cold Spring Harbor Perspectives in Biology, ISSN 1943-0264, E-ISSN 1943-0264, Vol. 8, no 5, a021873Article in journal (Refereed) Published
Resource type
Text
Abstract [en]

The transforming growth factor-beta (TGF-beta) is the prototype of the TGF-beta family of growth and differentiation factors, which is encoded by 33 genes in mammals and comprises homo- and heterodimers. This review introduces the reader to the TGF-beta family with its complexity of names and biological activities. It also introduces TGF-beta as the best-studied factor among the TGF-beta family proteins, with its diversity of roles in the control of cell proliferation and differentiation, wound healing and immune system, and its key roles in pathology, for example, skeletal diseases, fibrosis, and cancer.

Place, publisher, year, edition, pages
2016. Vol. 8, no 5, a021873
National Category
Cell and Molecular Biology
Identifiers
URN: urn:nbn:se:uu:diva-298909DOI: 10.1101/cshperspect.a021873ISI: 000377084600006OAI: oai:DiVA.org:uu-298909DiVA: diva2:948479
Available from: 2016-07-12 Created: 2016-07-12 Last updated: 2016-07-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
Ludwig Institute for Cancer Research
In the same journal
Cold Spring Harbor Perspectives in Biology
Cell and Molecular Biology

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 155 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf