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A bird's eye view of a deleterious recessive allele
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Evolutionary Biology.
2016 (English)In: Journal of Animal Ecology, ISSN 0021-8790, E-ISSN 1365-2656, Vol. 85, no 4, 855-856 p.Article in journal (Refereed) PublishedText
Abstract [en]

In Focus: Trask, A.E., Bignal, E.M., McCracken, D.I., Monaghan, P., Piertney, S.B. & Reid, J.M. (2016) Evidence of the phenotypic expression of a lethal recessive allele under inbreeding in a wild population of conservation concern. Journal of Animal Ecology, 85, 879-891. In this issue of Journal of Animal Ecology, Trask etal. () report on a strange, lethal, blindness that regularly affects chicks of an endangered bird population. The authors show that the inheritance mode of this blindness disease precisely matches the expectations of a recessive deleterious mutation. Intriguingly, there is also an indication that the disease-causing variant might be maintained in the population by balancing selection, due to a selective advantage for heterozygotes. Could this finding have consequences for conservation actions implemented for the population?

Place, publisher, year, edition, pages
2016. Vol. 85, no 4, 855-856 p.
National Category
URN: urn:nbn:se:uu:diva-299845DOI: 10.1111/1365-2656.12514ISI: 000378646800001PubMedID: 27279331OAI: oai:DiVA.org:uu-299845DiVA: diva2:950278
Available from: 2016-07-29 Created: 2016-07-28 Last updated: 2016-07-29Bibliographically approved

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