Data on the expression of cellular lncRNAs in human adenovirus infected cells
2016 (English)In: Data in Brief, ISSN 1529-4188, E-ISSN 1683-1470, Vol. 8, 1263-1279 p.Article in journal (Refereed) Published
Expression of cellular long non-coding RNAs (lncRNAs) in human primary lung fibroblasts (IMR-90) during the course of adenovirus type 2 (Ad2) infection was studied by strand-specific whole transcriptome sequencing. In total, 645 cellular lncRNAs were expressed at a significant level and 398 of them were changed more than 2-fold. The changes in expression followed a distinct temporal pattern. Significantly, 80% of the changes occurred at the late phase and 80% of the de-regulated lncRNAs were up-regulated. The three largest groups of deregulated lncRNAs were 125 antisense RNAs, 111 pseudogenes and 85 long intergenic non-coding RNAs (lincRNAs). Lastly, more than 36% of lncRNAs have been shown to interact with RNA binding proteins.
Place, publisher, year, edition, pages
Elsevier, 2016. Vol. 8, 1263-1279 p.
Adenovirus;Long noncodingRNA;IncRNA; IMR90
Research subject Medical Genetics
IdentifiersURN: urn:nbn:se:uu:diva-301964DOI: 10.1016/j.dib.2016.06.053PubMedID: 27547808OAI: oai:DiVA.org:uu-301964DiVA: diva2:955780
FunderMagnus Bergvall Foundation, 2015-01200Åke Wiberg Foundation