Reproductive Organ Impairments in Xenopus tropicalis Following Developmental Anti-androgenic Exposure
Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Exposure to endocrine disruptive compounds during critical developmental periods can cause various reproductive impairments in vertebrates. This project aims to investigate physiological reproductive effects in anti-androgen exposed Xenopus tropicalis. Metamorphosing male X. tropicalis were exposed to linuron or flutamide. Testicular histology and biometrical measurements were determined. Both linuron and flutamide caused reproductive organ impairments and decreased body weight. The outcome underscores the amphibian vulnerability to endocrine disruption during critical developmental periods.
Place, publisher, year, edition, pages
2016. , 24 p.
Pharmacology and Toxicology
IdentifiersURN: urn:nbn:se:uu:diva-301993OAI: oai:DiVA.org:uu-301993DiVA: diva2:955918
Subject / course
Master of Science Programme in Pharmacy