The Effect of Biocompatible Coating Layers on Magnetic Properties of Superparamagnetic Iron Oxide Nanoparticles
2004 (English)In: Hyperfine Interactions, no 156/157, 257-263 p.Article in journal (Refereed) Published
The effect of the surface coating on the magnetic properties of superparamagnetic iron oxide nanoparticles (SPION) with 8 nm in size has been studied. Four different biocompatible coating layers are considered: poly L,L-lactic acid (PLLA), poly e-caprolactone (PCL), bovine serum albumin (BSA) and gold. The presence of coating layer on the surface of SPION is confirmed by FT-IR spectroscopy. Mössbauer spectroscopy and magnetic susceptibility measurements show that for uncoated SPION and Au@SPION the superparamagnetic fraction is retained. The formation of clusters in the case of BSA@SPION and chain-like structure for PCL@SPION and PLLA@SPION increase the inter-particle interactions resulting in hyperfine magnetic structure observed in the Mössbauer spectra at ambient temperature.
Place, publisher, year, edition, pages
2004. no 156/157, 257-263 p.
magnetic nanoparticles, magnetite, superparamagnetism, Mossbauer spectroscopy, biocompatible coating
IdentifiersURN: urn:nbn:se:uu:diva-67716OAI: oai:DiVA.org:uu-67716DiVA: diva2:95627