uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates
Show others and affiliations
2004 (English)In: Journal of Bacteriology, ISSN 0021-9193, E-ISSN 1098-5530, Vol. 186, no 16, 5538-5542 p.Article in journal (Refereed) Published
Abstract [en]

Polymorphisms in the rifampin resistance mutation frequency (f) were studied in 696 Escherichia coli strains from Spain, Sweden, and Denmark. Of the 696 strains, 23% were weakly hypermutable (4 x 10(-8) < or = f < 4 x 10(-7)), and 0.7% were strongly hypermutable (f > or = 4 x 10(-7)). Weak mutators were apparently more frequent in southern Europe and in blood isolates (38%) than in urinary tract isolates (25%) and feces of healthy volunteers (11%).

Place, publisher, year, edition, pages
2004. Vol. 186, no 16, 5538-5542 p.
Keyword [en]
Anti-Bacterial Agents/pharmacology, Blood/microbiology, Denmark, Drug Resistance; Bacterial/*genetics, Escherichia coli/drug effects/*genetics/isolation & purification, Escherichia coli Infections/microbiology, Feces/microbiology, Genes; Bacterial, Humans, Mutation, Polymorphism; Genetic, Research Support; Non-U.S. Gov't, Rifampin/*pharmacology, Spain, Sweden, Urinary Tract Infections/microbiology
URN: urn:nbn:se:uu:diva-68004DOI: 10.1128/JB.186.16.5538-5542.2004PubMedID: 15292159OAI: oai:DiVA.org:uu-68004DiVA: diva2:95915
Available from: 2005-02-09 Created: 2005-02-09 Last updated: 2011-07-01Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15292159&dopt=Citation

Search in DiVA

By author/editor
Andersson, Dan I
In the same journal
Journal of Bacteriology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 270 hits
ReferencesLink to record
Permanent link

Direct link