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Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
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2004 (English)In: J Biol Chem, ISSN 0021-9258, Vol. 279, no 41, 42355-8 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2004. Vol. 279, no 41, 42355-8 p.
Keyword [en]
Amidohydrolases/*genetics/physiology, Animals, Blastocyst/metabolism, Carbohydrate Epimerases/chemistry, Chromatography; High Pressure Liquid, Chromatography; Ion Exchange, DNA; Complementary/metabolism, Embryo/metabolism, Gene Expression Regulation; Developmental, Genotype, Glucosamine/chemistry, Glucuronic Acid/metabolism, Glycosaminoglycans, Heparitin Sulfate/*biosynthesis, Iduronic Acid/metabolism, Mice, Mice; Transgenic, Nitrous Acid/metabolism, Polysaccharides/chemistry, Research Support; Non-U.S. Gov't, Reverse Transcriptase Polymerase Chain Reaction, Stem Cells/metabolism, Sulfates/chemistry, Sulfotransferases/*genetics/physiology, Sulfur/*metabolism
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URN: urn:nbn:se:uu:diva-68035PubMedID: 15319440OAI: oai:DiVA.org:uu-68035DiVA: diva2:95946
Available from: 2005-02-10 Created: 2005-02-10 Last updated: 2011-01-12

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Holmborn, KatarinaSmeds, EmanuelEriksson, IngerKjellén, Lena

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