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AT2-selective angiotensin II analogues containing tyrosine-functionalized 5,5-bicyclic thiazabicycloalkane dipeptide mimetics.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Medicinal Chemistry.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Medicinal Chemistry.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Medicinal Chemistry.
Department of Pharmaceutical Biosciences. Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Medicinal Chemistry.
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2004 (English)In: J Med Chem, ISSN 0022-2623, Vol. 47, no 24, 6009-19 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2004. Vol. 47, no 24, 6009-19 p.
Keyword [en]
Angiotensin II/*analogs & derivatives/*chemical synthesis/chemistry/pharmacology, Animals, Bicyclo Compounds; Heterocyclic/*chemical synthesis/chemistry/pharmacology, Crown Compounds/*chemical synthesis/chemistry/pharmacology, Dimethyl Sulfoxide, Dipeptides/*chemistry, Female, In Vitro, Liver/metabolism, Magnetic Resonance Spectroscopy, Models; Molecular, Molecular Conformation, Molecular Mimicry, Radioligand Assay, Rats, Receptor; Angiotensin; Type 1/metabolism, Receptor; Angiotensin; Type 2/*metabolism, Research Support; Non-U.S. Gov't, Solutions, Structure-Activity Relationship, Swine, Tyrosine/*chemistry, Uterus/metabolism
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URN: urn:nbn:se:uu:diva-68467PubMedID: 15537355OAI: oai:DiVA.org:uu-68467DiVA: diva2:96378
Available from: 2005-09-26 Created: 2005-09-26 Last updated: 2011-01-12

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Lindeberg, GunnarNyberg, FredKarlen, AndersHallberg, Anders

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