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The 5-HT1A receptor antagonist (S)-UH-301 augments the increase in extracellular concentrations of 5-HT in the frontal cortex produced by both acute and chronic treatment with citalopram
Uppsala University.
Uppsala University.
Uppsala University.
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1996 (English)In: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, Vol. 353, no 6, 630-640 p.Other (Other scientific)
Abstract [en]

In a recent study, utilizing single cell recording techniques, we have shown that administration of 5-HT1A receptor antagonists, e.g. (S)-UH-301, to rats concomitantly treated, acute or chronically, with the selective serotonin reuptake inhibitor (SSRI)

Place, publisher, year, pages
SPRINGER VERLAG , 1996. Vol. 353, no 6, 630-640 p.
Keyword [en]
antidepressant; citalopram; frontal cortex; microdialysis; serotonin; 5-HT1A receptor antagonist; (S)-UH-301; DORSAL RAPHE; ANTIDEPRESSANT TREATMENTS; BRAIN MICRODIALYSIS; SEROTONIN FUNCTION; UPTAKE INHIBITOR; RAT HIPPOCAMPUS; INVIVO; 5-HYDROXYTRYPTAMIN
Identifiers
URN: urn:nbn:se:uu:diva-69916OAI: oai:DiVA.org:uu-69916DiVA: diva2:97827
Note
Addresses: KAROLINSKA INST, DEPT PHYSIOL & PHARMACOL, DIV PHARMACOL, S-17177 STOCKHOLM, SWEDEN. ASTRA RES CTR AB, DEPT BEHAV & BIOCHEM PHARMACOL, S-15185 SODERTALJE, SWEDEN. UNIV UPPSALA, DEPT ORGAN PHARMACEUT CHEM, S-75123 UPPSALA, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17

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