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Addition of a signal peptide sequence to the alpha1D-adrenoceptor gene increases the density of receptors, as determined by [3H]-prazosin binding in the membranes.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Pharmaceutical Biosciences. Pharmacology. (Wikberg)
Faculty of Medicine, Department of Neuroscience. (Schiöth)
Faculty of Medicine, Department of Neuroscience. (Schiöth)
Faculty of Medicine, Department of Neuroscience. (Schiöth)
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2005 (English)In: Br J Pharmacol, ISSN 0007-1188, Vol. 144, no 5, 651-9 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2005. Vol. 144, no 5, 651-9 p.
Keyword [en]
Adrenergic alpha-Agonists/pharmacology, Adrenergic alpha-Antagonists/*pharmacology, Amino Acid Sequence, Animals, Binding Sites, COS Cells, Cell Membrane/*drug effects/metabolism, Cercopithecus aethiops, Comparative Study, Imidazoles/pharmacology, Inositol Phosphates/metabolism, Mice, Phenylephrine/pharmacology, Prazosin/*pharmacology, Protein Conformation, Protein Sorting Signals, Receptors; Adrenergic; alpha-1/chemistry/genetics/*metabolism, Research Support; Non-U.S. Gov't, Tritium
Identifiers
URN: urn:nbn:se:uu:diva-71560PubMedID: 15678090OAI: oai:DiVA.org:uu-71560DiVA: diva2:99471
Available from: 2006-03-08 Created: 2006-03-08 Last updated: 2011-01-12

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Petrovska, RamonaKlovins, Janis

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