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Optimal timing of aortic valve replacement for aortic stenosis: are we operating late?
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Thoracic Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Cardiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Physiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Thoracic Surgery.
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2003 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, E-ISSN 1651-2006, Vol. 37, no 5, 266-269 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To evaluate the adherence to current guidelines for surgery in patients with aortic valve stenosis.

DESIGN: From 1 January 1997 to 31 May 1999, 99 patients were accepted for aortic valve surgery with preserved left ventricular function and normal coronary angiogram. On admission for operation, 20 patients were evaluated regarding symptoms, exercise capacity, and left ventricular morphology and function.

RESULTS: There were 14 men and 6 women, mean age 64.3 years. Years from symptom onset varied from 2.1 to 3.2. Dyspnoea was the most common limiting symptom. Thirty per cent of the patients were classified as NYHA IIIB. Physical capacity was reduced to 79% of the expected. Left ventricular hypertrophy was present in 14/20 patients. Left ventricular systolic function was reduced with mean ejection fraction of 0.46. Diastolic dysfunction (E/A ratio <1) was present in 12 patients.

CONCLUSION: Many patients accepted for aortic valve replacement due to aortic stenosis show advanced disease and are referred for surgery later in the disease process than is recommended in the current guidelines.

Place, publisher, year, edition, pages
2003. Vol. 37, no 5, 266-269 p.
Keyword [en]
Aged, Aortic Valve Stenosis/physiopathology/*surgery/ultrasonography, Disease Progression, Exercise Test, Female, Heart Valve Prosthesis Implantation/*methods, Humans, Male, Middle Aged, Ventricular Dysfunction; Left/complications
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-72003DOI: 10.1080/14017430310001690PubMedID: 14534067OAI: oai:DiVA.org:uu-72003DiVA: diva2:99914
Available from: 2005-05-17 Created: 2005-05-17 Last updated: 2017-11-21Bibliographically approved

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Hellgren, LailaKvidal, Per-DavidStåhle, Elisabeth

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