Logotyp: till Uppsala universitets webbplats

uu.sePublikationer från Uppsala universitet
Ändra sökning
Avgränsa sökresultatet
1234567 1 - 50 av 774
RefereraExporteraLänk till träfflistan
Permanent länk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Träffar per sida
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sortering
  • Standard (Relevans)
  • Författare A-Ö
  • Författare Ö-A
  • Titel A-Ö
  • Titel Ö-A
  • Publikationstyp A-Ö
  • Publikationstyp Ö-A
  • Äldst först
  • Nyast först
  • Skapad (Äldst först)
  • Skapad (Nyast först)
  • Senast uppdaterad (Äldst först)
  • Senast uppdaterad (Nyast först)
  • Disputationsdatum (tidigaste först)
  • Disputationsdatum (senaste först)
  • Standard (Relevans)
  • Författare A-Ö
  • Författare Ö-A
  • Titel A-Ö
  • Titel Ö-A
  • Publikationstyp A-Ö
  • Publikationstyp Ö-A
  • Äldst först
  • Nyast först
  • Skapad (Äldst först)
  • Skapad (Nyast först)
  • Senast uppdaterad (Äldst först)
  • Senast uppdaterad (Nyast först)
  • Disputationsdatum (tidigaste först)
  • Disputationsdatum (senaste först)
Markera
Maxantalet träffar du kan exportera från sökgränssnittet är 250. Vid större uttag använd dig av utsökningar.
  • 1.
    Abdelmenan, Semira
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa. Addis Continental Inst Publ Hlth, Dept Epidemiol & Biostat, Addis Ababa, Ethiopia.;Univ Gondar, Inst Publ Hlth, Coll Med & Hlth Sci, Gondar, Ethiopia..
    Berhane, Hanna
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa. Addis Continental Inst Publ Hlth, Dept Nutr & Behav Sci, Addis Ababa, Ethiopia..
    Turner, Christopher
    Fac Epidemiol & Populat Hlth, Sch Hyg & Trop Med, Dept Populat Hlth, London, England..
    Worku, Alemayehu
    Addis Continental Inst Publ Hlth, Dept Epidemiol & Biostat, Addis Ababa, Ethiopia..
    Ekholm Selling, Katarina
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa.
    Ekström, Eva-Charlotte
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa.
    Berhane, Yemane
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa. Addis Continental Inst Publ Hlth, Dept Epidemiol & Biostat, Addis Ababa, Ethiopia..
    Perception of affordable diet is associated with pre-school children's diet diversity in Addis Ababa, Ethiopia: the EAT Addis survey2024Ingår i: BMC Nutrition, E-ISSN 2055-0928, Vol. 10, artikel-id 47Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Despite improvements in food access and nutrition security over the last few decades, malnutrition remains a major public health problem. One of the significant contributors to these problems is affordability of nutritious food. This study aimed to examine the association between perceived food affordability and pre-school children's diet diversity in Addis Ababa, Ethiopia.

    Methods: Cross-sectional data from 2017 to 18 were used for the analysis. A 24-hour dietary recall assessment was done to assess children's dietary diversity (DD). We used a modified operational definition of affordability indicator called perceived affordability of dietary diversity (afford-DD) to evaluate the impact of the food environment in terms of affordability at the household level. A sample (n 4,898) of children aged 6-59 months representative of households in Addis Ababa was randomly selected using a multistage sampling procedure including all districts in the city. Mixed-effects linear regression models were used to assess the association between children's DD and afford-DD.

    Results: The survey revealed that the mean (standard deviation [SD]) of children's DD was 3.9 [±1.4] while the mean [SD] of afford-DD was 4.6 [±2.1]. Overall, 59.8% of children met the minimum dietary diversity (≥ 4 food groups). White roots and tubers were the most commonly consumed food groups regardless of their affordability. Considerable variations were observed between households that reported the food item affordable and not affordable in consumption of Vitamin A rich vegetables and fruits, meat and fish, egg, and dairy. The children's DD was positively associated with afford-DD after adjusting for maternal education, household wealth status and other relevant confounding. Higher maternal education modified the association between affordability and children's diet diversity.

    Conclusions: This study suggests higher perceived food affordability was associated with better diet diversity in children. A higher level of maternal education had the potential to mitigate affordability challenges in meeting the children's dietary diversity needs. Our study emphasizes the need for inclusive food programs and nutrition interventions addressing social differences, intensifying efforts to make nutrient-rich diets affordable for the less privileged, and highlights the potential benefits of targeting maternal education in addressing child dietary diversity.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 2.
    Abdelmenan, Semira
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Internationell mödra- och barnhälsovård (IMCH), Internationell barnhälsa och nutrition. Addis Continental Institute of Public Health, 26751/1000 Addis Ababa, Ethiopia; Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, 196 Gondar, Ethiopia.
    Berhane, Hanna Y.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Internationell mödra- och barnhälsovård (IMCH), Internationell barnhälsa och nutrition. Addis Continental Institute of Public Health, 26751/1000 Addis Ababa, Ethiopia.
    Jirström, Magnus
    Trenholm, Jill
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Internationell mödra- och barnhälsovård (IMCH), Internationell kvinno- och mödrahälsovård och migration.
    Worku, Alemayehu
    Ekström, Eva-Charlotte
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Internationell mödra- och barnhälsovård (IMCH), Internationell barnhälsa och nutrition. Addis Continental Institute of Public Health, 26751/1000 Addis Ababa, Ethiopia.
    Berhane, Yemane
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Internationell mödra- och barnhälsovård (IMCH), Internationell barnhälsa och nutrition. Addis Continental Institute of Public Health, 26751/1000 Addis Ababa, Ethiopia.
    The Social Stratification of Availability, Affordability, and Consumption of Food in Families with Preschoolers in Addis Ababa: The EAT Addis Study in Ethiopia2020Ingår i: Nutrients, E-ISSN 2072-6643, Vol. 12, nr 10, artikel-id 3168Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this study was to understand the quality of diet being consumed among families in Addis Ababa, and to what extent social stratification and perceptions of availability and affordability affect healthy food consumption. Data were collected from 5467 households in a face-to-face interview with mothers/caretakers and analyzed using mixed effect logistic regression models. All family food groups, except fish were perceived to be available by more than 90% of the participants. The food groups cereals/nuts/seeds, other vegetables, and legumes were considered highly affordable (80%) and were the most consumed (>75%). Households with the least educated mothers and those in the lowest wealth quintile had the lowest perception of affordability and also consumption. Consumption of foods rich in micronutrients and animal sources were significantly higher among households with higher perceived affordability, the highest wealth quintile, and with mothers who had better education. Households in Addis Ababa were generally seen to have a monotonous diet, despite the high perceived availability of different food groups within the food environment. There is a considerable difference in consumption of nutrient-rich foods across social strata, hence the cities food policies need to account for social differences in order to improve the nutritional status of the community.

    Ladda ner fulltext (pdf)
    fulltext
  • 3.
    Abrahamsson, Lillemor
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV).
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV). Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap.
    Principles of nutritional assessment2006Ingår i: Scandinavian Journal of Food and Nutrition, ISSN 1748-2976, E-ISSN 1748-2984, Vol. 50, nr 4, s. 177-177Artikel, recension (Övrig (populärvetenskap, debatt, mm))
  • 4.
    Abrahamsson, Lillemor
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV). kost.
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV). Medicinska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap.
    Becker, Wulf
    Medicinska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap. Klinisk nutrition och metabolism.
    Nilsson, Gerd
    Näringslära för högskolan2006Bok (Övrig (populärvetenskap, debatt, mm))
  • 5. Abrahamsson, Lillemor
    et al.
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Nilsson, Gerd
    Näringslära för högskolan: Från grundläggande till avancerad nutrition2013 (uppl. 6)Bok (Övrig (populärvetenskap, debatt, mm))
  • 6.
    Abrahamsson, Lillemor
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV).
    Ekblad, Jenny
    Behov under livscykeln och varianter av kost2006Ingår i: Näringslära för högskolan, Liber AB, Stockholm , 2006, s. 356-393Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
  • 7.
    Abrahamsson, Lillemor
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV).
    Löf, Marie
    Proteiner2006Ingår i: Näringslära för högskolan, Liber AB, Stockholm , 2006, s. 131-165Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
  • 8.
    Adamsson, Viola
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Reumark, Anna
    Marklund, Matti
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Larsson, Anders
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Biokemisk struktur och funktion.
    Risérus, Ulf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Role of a prudent breakfast in improving cardiometabolic risk factors in subjects with hypercholesterolemia: A randomized controlled trial2015Ingår i: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983, Vol. 34, nr 1, s. 20-26Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND & AIMS:

    It is unclear whether advising a prudent breakfast alone is sufficient to improve blood lipids and cardiometabolic risk factors in overweight hypercholesterolemic subjects. The aim of this study was to investigate whether a prudent low-fat breakfast (PB) rich in dietary fiber lowers low-density lipoprotein cholesterol (LDL-C) and other cardiometabolic risk factors in subjects with elevated LDL-cholesterol levels.

    METHODS:

    In a parallel, controlled, 12-week study, 79 healthy overweight subjects (all regular breakfast eaters) were randomly allocated to a group that received a PB based on Nordic foods provided ad libitum or a control group that consumed their usual breakfast. The primary outcome was plasma LDL-C. Secondary outcomes were other blood lipids, body weight, sagittal abdominal diameter (SAD), glucose tolerance, insulin sensitivity and inflammation markers (C-reactive protein [CRP] and tumor necrosis factor receptor-2 [TNF-R2]), and blood pressure. The PB was in accordance with national and Nordic nutrition recommendations and included oat bran porridge with low-fat milk or yogurt, bilberry or lingonberry jam, whole grain bread, low-fat spread, poultry or fatty fish, and fruit.

    RESULTS:

    No differences were found in LDL-C, other blood lipids, body weight, or glucose metabolism, but SAD, plasma CRP, and TNF-R2 decreased more during PB compared with controls (p < 0.05). In the overall diet, PB increased dietary fiber and β-glucan compared with controls (p < 0.05).

    CONCLUSIONS:

    Advising a prudent breakfast for 3 months did not influence blood lipids, body weight, or glucose metabolism but reduced markers of visceral fat and inflammation. The trial was registered in the Current Controlled Trials database (http://www.controlled-trials.com); International Standard Randomized Controlled Trial Number (ISRCTN): 84550872.

    Ladda ner fulltext (pdf)
    fulltext
  • 9.
    Adolfsson, Päivi
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Forskning om funktionshinder och habilitering.
    Ek, Pia
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi.
    Umb-Carlsson, Õie
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Forskning om funktionshinder och habilitering.
    Dietitians’ challenges when consulting to adults with intellectual disabilities2019Ingår i: Tizard Learning Disability Review, ISSN 1359-5474, E-ISSN 2042-8782, ISSN ISSN 1359-5474,, Vol. 24, nr 4, s. 153-162Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: The purpose of this paper is to investigate registered dietitians' (RDs) experiences in consulting to adults with intellectual disabilities (ID) in Sweden.

    Design/methodology/approach: A descriptive study using a study-specific web-based questionnaire was administered, comprising both multiple-choice questions with a space for comments and open-ended questions. The open-ended answers and comments from 53 respondents were analysed with systematic text condensation.

    Findings: Four categories were identified: RDs' experiences from the first meeting; explanations for late initial contact; the actions taken by RDs; and necessary measures for more sustainable nutrition care. Ten sub-categories described the challenges that RDs experience in more detail.

    Practical implications: It is necessary to provide adults with ID and their supporting staff with individually tailored nutritional information. Individuals with ID must be actively involved in lifestyle changes that affect their everyday life. The RD must be included in the interdisciplinary team supporting adults with ID. If a new practice is to be implemented, it should be compatible with the existing values of adults with ID and their staff and must be feasible to implement in the everyday life of the individual.

    Originality/value: This paper identified several barriers that should be overcome in relation to the preparation of RDs for consultation with adults with ID about nutritional health issues. A systematic structure, knowledge about nutrition and knowledge about adults with ID and their living situations are needed. An assessment instrument may meet health promotion needs and facilitate longitudinal follow-ups of nutritional problems.

    Ladda ner fulltext (pdf)
    fulltext
  • 10.
    Adolfsson, Päivi
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Forskning om funktionshinder och habilitering.
    Ek, Pia
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi.
    Umb-Carlsson, Öie
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Forskning om funktionshinder och habilitering.
    Challenges for registered dietitians working with food related health promotion for adults with IDD in supported housing2018Konferensbidrag (Övrigt vetenskapligt)
  • 11.
    Adolfsson, Päivi
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap.
    Hysing, Jennie
    City of Stockholm, Sweden..
    Ek, Pia
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Dietitians’ endeavor to contribute to the nutritional health of children and youth with intellectual disability and autism2023Ingår i: International Journal of Developmental Disabilities, ISSN 2047-3869Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of the present study was to explore the experiences of registered dietitians (RD) who consult children and youth with intellectual disability (ID) and autism. Another aim was to investigate how knowledge and working methods were transferred to RDs working with adults with ID and autism. Twenty-six RDs completed a web-based study-specific questionnaire with multiple-choice and open-ended questions. The respondents’ comments and responses to the open-ended questions were analyzed using systematic text condensation. The analyses resulted in four categories: Reachability and accessibility of RDs, Clients do not comply with RDs’ dietary advice, RD finds individual solutions and Better collaboration for better knowledge. It was noteworthy that RDs’ undergraduate education did not prepare them for clients with ID and autism. Instead, they learned by doing and from other professionals at the clinic if they collaborate with them or were part in teams around the client. The RDs reported a lack of national routines for the transition process of nutrition support from young to adult.

    Ladda ner fulltext (pdf)
    fulltext
  • 12.
    Adolfsson, Päivi
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap. Centrum för forskning om funktionshinder, Centre for Disability research.
    Lewin, Barbro
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap.
    Mattsson Sydner, Ylva
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Fjellström, Christina
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Food habits among persons with intellectual disabilities (ID)2004Konferensbidrag (Refereegranskat)
  • 13.
    Ahmad, Shafqat
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Molekylär epidemiologi. Harvard Medical School; Harvard T.H. Chan School of Public Health.
    Demler, O. V.
    Sun, Q.
    Moorthy, M. V.
    Li, C.
    Lee, I.-M.
    Ridker, P. M.
    Manson, J. E.
    Hu, F. B.
    Fall, Tove
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Molekylär epidemiologi.
    Chasman, D. I.
    Cheng, S.
    Pradhan, A.
    Mora, S.
    Association of the Mediterranean Diet With Onset of Diabetes in the Women’s Health Study2020Ingår i: JAMA Network Open, E-ISSN 2574-3805, Vol. 3, nr 11, artikel-id e2025466Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Importance  Higher Mediterranean diet (MED) intake has been associated with reduced risk of type 2 diabetes, but underlying biological mechanisms are unclear.

    Objective  To characterize the relative contribution of conventional and novel biomarkers in MED-associated type 2 diabetes risk reduction in a US population.

    Design, Setting, and Participants  This cohort study was conducted among 25 317 apparently healthy women. The participants with missing information regarding all traditional and novel metabolic biomarkers or those with baseline diabetes were excluded. Participants were invited for baseline assessment between September 1992 and May 1995. Data were collected from November 1992 to December 2017 and analyzed from December 2018 to December 2019.

    Exposures  MED intake score (range, 0 to 9) was computed from self-reported dietary intake, representing adherence to Mediterranean diet intake.

    Main Outcomes and Measures  Incident cases of type 2 diabetes, identified through annual questionnaires; reported cases were confirmed by either telephone interview or supplemental questionnaire. Proportion of reduced risk of type 2 diabetes explained by clinical risk factors and a panel of 40 biomarkers that represent different physiological pathways was estimated.

    Results  The mean (SD) age of the 25 317 female participants was 52.9 (9.9) years, and they were followed up for a mean (SD) of 19.8 (5.8) years. Higher baseline MED intake (score ≥6 vs ≤3) was associated with as much as a 30% lower type 2 diabetes risk (age-adjusted and energy-adjusted hazard ratio, 0.70; 95% CI, 0.62-0.79; when regression models were additionally adjusted with body mass index [BMI]: hazard ratio, 0.85; 95% CI, 0.76-0.96). Biomarkers of insulin resistance made the largest contribution to lower risk (accounting for 65.5% of the MED–type 2 diabetes association), followed by BMI (55.5%), high-density lipoprotein measures (53.0%), and inflammation (52.5%), with lesser contributions from branched-chain amino acids (34.5%), very low-density lipoprotein measures (32.0%), low-density lipoprotein measures (31.0%), blood pressure (29.0%), and apolipoproteins (23.5%), and minimal contribution (≤2%) from hemoglobin A1c. In post hoc subgroup analyses, the inverse association of MED diet with type 2 diabetes was seen only among women who had BMI of at least 25 at baseline but not those who had BMI of less than 25 (eg, women with BMI <25, age- and energy-adjusted HR for MED score ≥6 vs ≤3, 1.01; 95% CI, 0.77-1.33; P for trend = .92; women with BMI ≥25: HR, 0.76; 95% CI, 0.67-0.87; P for trend < .001).

    Conclusions and Relevance  In this cohort study, higher MED intake scores were associated with a 30% relative risk reduction in type 2 diabetes during a 20-year period, which could be explained in large part by biomarkers of insulin resistance, BMI, lipoprotein metabolism, and inflammation.

    Ladda ner fulltext (pdf)
    fulltext
  • 14. Ajenikoko, Adefunke
    et al.
    Ide, Nicole
    Shivashankar, Roopa
    Ge, Zeng
    Marklund, Matti
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Anderson, Cheryl
    Atun, Amy
    Thomson, Alexander
    Henry, Megan E
    Cobb, Laura K
    Core Strategies to Increase the Uptake and Use of Potassium-Enriched Low-Sodium Salt.2021Ingår i: Nutrients, E-ISSN 2072-6643, Vol. 13, nr 9, s. 3203-, artikel-id 3203Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Excess sodium consumption and insufficient potassium intake contribute to high blood pressure and thus increase the risk of heart disease and stroke. In low-sodium salt, a portion of the sodium in salt (the amount varies, typically ranging from 10 to 50%) is replaced with minerals such as potassium chloride. Low-sodium salt may be an effective, scalable, and sustainable approach to reduce sodium and therefore reduce blood pressure and cardiovascular disease at the population level. Low-sodium salt programs have not been widely scaled up, although they have the potential to both reduce dietary sodium intake and increase dietary potassium intake. This article proposes a framework for a successful scale-up of low-sodium salt use in the home through four core strategies: availability, awareness and promotion, affordability, and advocacy. This framework identifies challenges and potential solutions within the core strategies to begin to understand the pathway to successful program implementation and evaluation of low-sodium salt use.

    Ladda ner fulltext (pdf)
    fulltext
  • 15.
    Akbaraly, Tasmine
    et al.
    PSL Res Univ, Univ Montpellier, MMDN, EPHE, INSERM, U1198, Montpellier, France; UCL, Dept Epidemiol & Publ Hlth, London, England; Hosp & Univ Res Ctr Montpellier, Dept Psychiat, Montpellier, France; Hosp & Univ Res Ctr Montpellier, Autism Resources Ctr, Montpellier, France.
    Sexton, Claire
    Univ Oxford, FMRIB Ctr, Nuffield Dept Clin Neurosci, Oxford, England.
    Zsoldos, Eniko
    Univ Oxford, Dept Psychiat, Neurobiol Ageing Grp, Oxford, England.
    Mahmood, Abda
    Univ Oxford, Dept Psychiat, Neurobiol Ageing Grp, Oxford, England.
    Filippini, Nicola
    Univ Oxford, Dept Psychiat, Neurobiol Ageing Grp, Oxford, England.
    Kerleau, Clarisse
    PSL Res Univ, Univ Montpellier, MMDN, EPHE, INSERM, U1198, Montpellier, France.
    Verdier, Jean-Michel
    PSL Res Univ, Univ Montpellier, MMDN, EPHE, INSERM, U1198, Montpellier, France.
    Virtanen, Marianna
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Folkhälsovetenskap.
    Gabelle, Audrey
    Univ Montpellier, Memory Resources & Res Ctr Alzheimers Dis & Relat, Dept Neurol, Gui de Chauliac Hosp, INSERM, U1183, Montpellier, France.
    Ebmeier, Klaus
    Univ Oxford, Dept Psychiat, Neurobiol Ageing Grp, Oxford, England.
    Kivimäki, Mika
    UCL, Dept Epidemiol & Publ Hlth, London, England.
    Association of Long-Term Diet Quality with Hippocampal Volume: Longitudinal Cohort Study2018Ingår i: American Journal of Medicine, ISSN 0002-9343, E-ISSN 1555-7162, Vol. 131, nr 11, s. 1372-1381.e4Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Diet quality is associated with brain aging outcomes. However, few studies have explored in humans the brain structures potentially affected by long-term diet quality. We examined whether cumulative average of the Alternative Healthy Eating Index 2010 (AHEI-2010) score during adult life (an 11-year exposure period) is associated with hippocampal volume.

    Methods: Analyses were based on data from 459 participants of the Whitehall II imaging sub-study (mean age [standard deviation] (SD) = 59.6 [5.3] years in 2002-2004, 19.2% women). Multimodal magnetic resonance imaging examination was performed at the end of follow-up (2015-2016). Structural images were acquired using a high-resolution 3-dimensional T1-weighted sequence and processed with Functional Magnetic Resonance Imaging of the Brain Software Library (FSL) tools. An automated model-based segmentation and registration tool was applied to extract hippocampal volumes.

    Results: Higher AHEI-2010 cumulative average score (reflecting long-term healthy diet quality) was associated with a larger total hippocampal volume. For each 1 SD (SD = 8.7 points) increment in AHEI-2010 score, an increase of 92.5 mm3 (standard error = 42.0 mm3) in total hippocampal volume was observed. This association was independent of sociodemographic factors, smoking habits, physical activity, cardiometabolic health factors, cognitive impairment, and depressive symptoms, and was more pronounced in the left hippocampus than in the right hippocampus. Of the AHEI-2010 components, no or light alcohol consumption was independently associated with larger hippocampal volume.

    Conclusions: Higher long-term AHEI-2010 scores were associated with larger hippocampal volume. Accounting for the importance of hippocampal structures in several neuropsychiatric diseases, our findings reaffirm the need to consider adherence to healthy dietary recommendation in multi-interventional programs to promote healthy brain aging.

    Ladda ner fulltext (pdf)
    fulltext
  • 16.
    Akesson, Agneta
    et al.
    Karolinska Inst, Inst Environm Med, Box 210, SE-17177 Stockholm, Sweden..
    Donat-Vargas, Carolina
    Karolinska Inst, Inst Environm Med, Box 210, SE-17177 Stockholm, Sweden..
    Berglund, Marika
    Karolinska Inst, Inst Environm Med, Box 210, SE-17177 Stockholm, Sweden..
    Glynn, Anders
    Swedish Univ Agr Sci, Dept Biomed Sci & Vet Publ Hlth, Box 7028, SE-75007 Uppsala, Sweden..
    Wolk, Alicja
    Karolinska Inst, Inst Environm Med, Box 210, SE-17177 Stockholm, Sweden..
    Kippler, Maria
    Karolinska Inst, Inst Environm Med, Box 210, SE-17177 Stockholm, Sweden..
    Dietary exposure to polychlorinated biphenyls and risk of heart failure - A population-based prospective cohort study2019Ingår i: Environment International, ISSN 0160-4120, E-ISSN 1873-6750, Vol. 126, s. 1-6Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Beneficial effects of fish consumption on heart failure (HF) may be modified by contaminants in fish. Polychlorinated biphenyls (PCBs) are of particular concern as they have been associated with well-established risk factors of HF, but current data are limited. Objectives: We aimed to assess the association between dietary PCB exposure and risk of HF, accounting for dietary intake of long-chain omega-3 fish fatty acids. Design: We used the prospective population-based research structure SIMPLER (previously the Swedish Mammography Cohort and Cohort of Swedish Men) comprising 32,952 women and 36,546 men, free from cancer, cardiovascular disease and diabetes at baseline in 1997. Validated estimates of dietary PCBs and long-chain omega-3 fish fatty acids [eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)] were obtained via a food frequency questionnaire at baseline. Incident cases of HF were ascertained through register linkage. Results: During an average of 12 years of follow-up, we ascertained 2736 and 3128 incident cases of HF in women and men, respectively. In multivariable-adjusted models, mutually adjusted for PCBs and EPA-DHA, the relative risk (RR) for dietary PCB exposure was 1.48 (95% CI 1.12-1.96) in women and 1.42 (95% CI 1.08-1.86) in men, comparing extreme quintiles. Corresponding RRs for EPA-DHA intake were 0.71 (95% CI 0.54-0.93) and 0.82 (95% CI 0.63-1.07), respectively. Conclusions: Dietary exposure to PCBs was associated with an increased risk of HF in both women and men. EPA-DHA intake was associated with a lower risk of HF in women, with a similar tendency in men.

  • 17. Akesson, Agneta
    et al.
    Weismayer, Christoph
    Newby, P. K.
    Wolk, Alicja
    Combined effect of low-risk dietary and lifestyle behaviors in primary prevention of myocardial infarction in women2007Ingår i: Archives of Internal Medicine, ISSN 0003-9926, E-ISSN 1538-3679, Vol. 167, nr 19, s. 2122-2127Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Limited data are available on the benefit of combining healthy dietary and lifestyle behaviors in the prevention of myocardial infarction (MI) in women. Methods: We used factor analysis to identify a lowrisk behavior - based dietary pattern in 24 444 postmenopausal women from the population- based prospective Swedish Mammography Cohort who were free of diagnosed cancer, cardiovascular disease, and diabetes mellitus at baseline (September 15, 1997). We also defined 3 low- risk lifestyle factors: nonsmoking, waist- hip ratio less than the 75th percentile (< 0.85), and being physically active (at least 40 minutes of daily walking or bicycling and 1 hour of weekly exercise). Results: During 6.2 years (151 434 person- years) of followup, we ascertained 308 cases of primary MI. Two major identified dietary patterns, "healthy" and "alcohol," were significantly associated with decreased risk of MI. The low- risk diet (high scores for the healthy dietary pattern) characterized by a high intake of vegetables, fruit, whole grains, fish, and legumes, in combination with moderate alcohol consumption (>= 5 g of alcohol per day), along with the 3 low-risk lifestyle behaviors, was associated with 92% decreased risk (95% confidence interval, 72%- 98%) compared with findings in women without any low-risk diet and lifestyle factors. This combination of healthy behaviors, present in 5%, may prevent 77% of MIs in the study population. Conclusion: Most MIs in women may be preventable by consuming a healthy diet and moderate amounts of alcohol, being physically active, not smoking, and maintaining a healthy weight.

  • 18.
    Akpan, Edifofon
    et al.
    Univ Melbourne, Ctr Hlth Policy, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia..
    Hossain, Sheikh Jamal
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Internationell barnhälsa och nutrition. Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh.;Uppsala Univ, Dept Womens & Childrens Hlth, Uppsala, Sweden..
    Devine, Angela
    Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia.;Charles Darwin Univ, Menzies Sch Hlth Res, Div Global & Trop Hlth, Darwin, NT, Australia..
    Braat, Sabine
    Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia.;Walter & Eliza Hall Inst Med Res, Populat Hlth & Immun Div, Parkville, Vic, Australia.;Univ Melbourne, Dept Med Peter Doherty Inst, Parkville, Vic, Australia..
    Hasan, Mohammed, I
    Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh..
    Tipu, S. M. Mulk Uddin
    Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh..
    Bhuiyan, Mohammad Saiful Alam
    Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh..
    Hamadani, Jena D.
    Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh..
    Biggs, Beverley-Ann
    Univ Melbourne, Dept Med Peter Doherty Inst, Parkville, Vic, Australia..
    Pasricha, Sant-Rayn
    Walter & Eliza Hall Inst Med Res, Populat Hlth & Immun Div, Parkville, Vic, Australia.;Royal Melbourne Hosp, Diagnost Hematol, Parkville, Vic, Australia.;Peter MacCallum Canc Ctr, Clin Hematol, Parkville, Vic, Australia.;Royal Melbourne Hosp, Parkville, Vic, Australia.;Univ Melbourne, Dept Med Biol, Parkville, Vic, Australia..
    Carvalho, Natalie
    Univ Melbourne, Ctr Hlth Policy, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia..
    Cost-effectiveness of universal iron supplementation and iron-containing micronutrient powders for anemia among young children in rural Bangladesh: analysis of a randomized, placebo-controlled trial2022Ingår i: American Journal of Clinical Nutrition, ISSN 0002-9165, E-ISSN 1938-3207, Vol. 116, nr 5, s. 1303-1313Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Universal provision of iron supplements or iron-containing multiple micronutrient powders (MNPs) is widely used to prevent anemia in young children in low- and middle-income countries. The BRISC (Benefits and Risks of Iron Interventions in Children) trial compared iron supplements and MNPs with placebo in children <2 y old in rural Bangladesh. Objectives: We aimed to assess the cost-effectiveness of iron supplements or iron-containing MNPs among young children in rural Bangladesh. Methods: We did a cost-effectiveness analysis of MNPs and iron supplements using the BRISC trial outcomes and resource use data, and programmatic data from the literature. Health care costs were assessed from a health system perspective. We calculated incremental cost-effectiveness ratios (ICERs) in terms of US$ per disability-adjusted life-year (DALY) averted. To explore uncertainty, we constructed cost-effectiveness acceptability curves using bootstrapped data over a range of cost-effectiveness thresholds. One- and 2-way sensitivity analyses tested the impact of varying key parameter values on our results. Results: Provision of MNPs was estimated to avert 0.0031 (95% CI: 0.0022, 0.0041) DALYs/child, whereas iron supplements averted 0.0039 (95% CI: 0.0030, 0.0048) DALYs/child, over 1 y compared with no intervention. Incremental mean costs were $0.75 (95% CI: 0.73, 0.77) for MNPs compared with no intervention and $0.64 ($0.62, $0.67) for iron supplements compared with no intervention. Iron supplementation dominated MNPs because it was cheaper and averted more DALYs. Iron supplementation had an ICER of $1645 ($1333, $2153) per DALY averted compared with no intervention, and had a 0% probability of being the optimal strategy at cost-effectiveness thresholds of $200 (reflecting health opportunity costs in Bangladesh) and $985 [half of gross domestic product (GDP) per capita] per DALY averted. Scenario and sensitivity analyses supported the base case findings. Conclusions: These findings do not support universal iron supplementation or micronutrient powders as a cost-effective intervention for young children in rural Bangladesh.

  • 19.
    Al-Adili, Lina
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap. uppsala university.
    The evaluation process of nutrition interventions for patients at risk of malnutrition: From a person-centred perspective2023Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    This thesis is aimed at exploring the process of evaluating nutrition interventions for patients at risk of malnutrition from a person-centred perspective. 

    An explorative cross-sectional study was conducted based on data from the International Nutrition Care Process and Terminology Implementation Survey (INIS). Associations between the reported documentation of goals and outcomes and the reported implementation of the nutrition care process and its terminology, demographic factors, and factors associated with the workplace were explored. Responses were received from 347 Scandinavian dietitians. Strong associations were found between the implementation of nutrition monitoring and evaluation terminology and the documentation of goals and outcomes. Standardisation may support the documentation of goals and outcomes, and improve nutrition monitoring and evaluation. 

    Focus group interviews were held with Swedish dietitians working in hospital and primary healthcare settings. The dietitians’ reflections on the process of nutrition monitoring and evaluation (Paper II) and the goal-setting process (Paper III) with patients at risk of malnutrition in nutrition intervention were explored. A lack of routine and structure in the process of evaluation and a lack of shared decision-making (SDM) in goal-setting was found. Dietitians described qualitative subjective outcomes as being most important to patients but that these are only implied in the nutrition intervention. They highlighted discrepancies between their clinically oriented goals and the patients’ own goals. The clarification of patients’ perspectives in the evaluation process is necessary to promote person-centredness, improve communication, and support the evidence-informed practice of nutrition intervention.

    An interview study with patients at risk of malnutrition was conducted. Patients’ experiences, perspectives and needs concerning goals in nutrition intervention were explored. Patients rarely reflected on goals in nutrition interventions, instead they described striving towards increased strength and energy. Goal-setting is part of the dietitian’s structured way of working, while the patient’s life-world is complex and unstructured. Elucidating patients’ goals may counteract the discrepancies between the dietitians’ clinically oriented goals and patients’ perspectives.

    In summary, this thesis highlights the need for tools and strategies for the improvement of the evaluation process in nutrition intervention. The person-centred practice of the evaluation process is described in this thesis as key to improving this process. This can be achieved through exploring what matters to patients in terms of perspectives, goals, and priorities, creating partnerships through involving patients in goal-setting and communicating feedback, and documenting and evaluating outcomes that are meaningful to patients.  

    Delarbeten
    1. Self‐reported documentation of goals and outcomes of nutrition care: A cross‐sectional survey study of Scandinavian dietitians
    Öppna denna publikation i ny flik eller fönster >>Self‐reported documentation of goals and outcomes of nutrition care: A cross‐sectional survey study of Scandinavian dietitians
    Visa övriga...
    2023 (Engelska)Ingår i: Scandinavian Journal of Caring Sciences, ISSN 0283-9318, E-ISSN 1471-6712, Vol. 37, nr 2, s. 472-485Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Background

    The documentation of goals and outcomes of nutrition care in Electronic Health Records is insufficient making further exploration of this of particular interest. Identifying common features in documentation practice among Scandinavian dietitians might provide information that can support improvement in this area.

    Aims

    To explore the associations between clinical dietitians' self-reported documentation of patients' goals and outcomes and demographic factors, self-reported implementation of the systematic framework the Nutrition Care Process 4th step (NCP) and its associated terminology, and factors associated with the workplace.

    Methods

    Data from a cross-sectional study based on a previously tested web-based survey (INIS) disseminated in 2017 to dietitians in Scandinavia (n = 494) was used. Respondents were recruited through e-mail lists, e-newsletters and social media groups for dietitians. Associations between countries regarding the reported documentation of goals and outcomes, implementation levels of the NCP 4th step, demographic information and factors associated with the workplace were measured through Chi-square test. Associations between dependent- and independent variables were measured through logistic regression analysis.

    Results

    Clinically practicing dietitians (n = 347) working in Scandinavia, Sweden (n = 249), Norway (n = 60), Denmark (n = 38), who had completed dietetic education participated. The reported documentation of goals and outcomes from nutrition intervention was highly associated with the reported implementation of NCP 4th step terminology (OR = 5.26; p = 0.009, OR = 3.56; p = 0.003), support from the workplace (OR = 4.0, p < 0.001, OR = 8.89, p < 0.001) and area of practice (OR = 2.02, p = 0.017). Years since completed dietetic training and educational level did not have any significant associations with documentation practice regarding goals and outcomes.

    Conclusion

    Findings highlight strong associations between the implementation of the NCP 4th step terminology and the documentation of goals and outcomes. Strategies to support dietitians in using standardized terminology and the development of tools for comprehensive documentation of evaluation of goals and outcome are required.

    Ort, förlag, år, upplaga, sidor
    John Wiley & Sons, 2023
    Nationell ämneskategori
    Näringslära
    Identifikatorer
    urn:nbn:se:uu:diva-491136 (URN)10.1111/scs.13131 (DOI)000878420100001 ()
    Forskningsfinansiär
    Uppsala universitet
    Tillgänglig från: 2022-12-19 Skapad: 2022-12-19 Senast uppdaterad: 2023-10-12Bibliografiskt granskad
    2. Discrepancy in the evaluation of explicit and implicit nutrition care outcomes for patients at risk of malnutrition: A qualitative study
    Öppna denna publikation i ny flik eller fönster >>Discrepancy in the evaluation of explicit and implicit nutrition care outcomes for patients at risk of malnutrition: A qualitative study
    Visa övriga...
    2022 (Engelska)Ingår i: Journal of human nutrition and dietetics, ISSN 0952-3871, E-ISSN 1365-277X, Vol. 35, nr 3, s. 494-503Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    BACKGROUND: Nutrition care plays a significant role in the prevention and treatment of malnutrition, although the challenge to establish the precise impact of a nutrition intervention on patient outcomes remains. Malnutrition can be associated with diverse underlying diseases and an increased risk of complications, which increases the difficulty of monitoring and evaluating the nutrition intervention. The aim is to gain an understanding of dietitians' reflections concerning nutrition care outcomes of interventions in patients at risk of malnutrition.

    METHODS: Six semi-structured audio-recorded focus group discussions with registered dietitians from primary healthcare and hospitals (n = 29) in Sweden were held at the dietitians' place of work or at the University. Focus group transcripts were analysed thematically to reveal patterns in the data and identify themes and subthemes.

    RESULTS: The dietitians described an approach to nutrition monitoring and evaluation of patients at risk of malnutrition that was categorised into three themes: (i) quantitative explicit outcomes, based on objective measures and described as rigorous; (ii) quantitative estimated outcomes, based on estimates and described as less rigorous and (iii) qualitative implicit outcomes, based on patients' subjective perceptions and experiences of their health and described as difficult to measure.

    CONCLUSIONS: Findings indicate the need for new strategies to promote systematic and comprehensive nutrition monitoring and evaluation.

    Ort, förlag, år, upplaga, sidor
    John Wiley & Sons, 2022
    Nyckelord
    at risk of malnutrition, dietitian, monitoring and evaluation, nutrition care process, patient outcome assessment, qualitative research
    Nationell ämneskategori
    Näringslära
    Identifikatorer
    urn:nbn:se:uu:diva-475489 (URN)10.1111/jhn.12931 (DOI)000693726800001 ()34231280 (PubMedID)
    Forskningsfinansiär
    Uppsala universitet
    Tillgänglig från: 2022-06-02 Skapad: 2022-06-02 Senast uppdaterad: 2023-11-20Bibliografiskt granskad
    3. Setting goals with patients at risk of malnutrition: A focus group study with clinical dietitians
    Öppna denna publikation i ny flik eller fönster >>Setting goals with patients at risk of malnutrition: A focus group study with clinical dietitians
    Visa övriga...
    2022 (Engelska)Ingår i: Patient Education and Counseling, ISSN 0738-3991, E-ISSN 1873-5134, Vol. 105, nr 7, s. 2103-2109Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Objective: Setting goals collaboratively with patients is a key aspect in shared decision-making (SDM) in malnutrition interventions. The aim, therefore, was to gain an understanding of clinical dietitians' reflections regarding the process of goal-setting with patients at risk of malnutrition.

    Methods: Six semi-structured audio-recorded focus group discussions were held with registered dietitians (n = 29) from primary healthcare and hospitals in Sweden. Focus group transcripts were analysed thematically to find patterns in the data and identify themes.

    Results: Dietitians expressed striving to explore patients' narratives, capabilities, and resources before deciding on goals. They described different strategies in counseling patients and a lack of patient participation in the goal setting. They emphasized the difficulties of setting feasible goals due to discrepancies between their clinically oriented goals and patients' personal goals.

    Conclusion: Findings highlight a gap in the process of setting goals for patients at risk of malnutrition, where patients' participation was lacking. Education in SDM, and strategies and tools to support dietitians in involving patients in goal-setting, are required to bridge the gap and promote person-centeredness. Practice implications: Findings may be further used to develop tools and strategies, and design studies on the implementation of and education in SDM and goal-setting for malnutrition interventions.

    Ort, förlag, år, upplaga, sidor
    ElsevierElsevier BV, 2022
    Nyckelord
    At risk of malnutrition, Person-centered care, Shared decision-making, Collaborative goal-setting, Qualitative research, Dietetic counseling
    Nationell ämneskategori
    Näringslära Omvårdnad
    Identifikatorer
    urn:nbn:se:uu:diva-481294 (URN)10.1016/j.pec.2022.02.015 (DOI)000815980300015 ()35241324 (PubMedID)
    Tillgänglig från: 2022-08-09 Skapad: 2022-08-09 Senast uppdaterad: 2024-01-15Bibliografiskt granskad
    4. Nutrition intervention goals from the perspectives of patients at risk of malnutrition: A qualitative study
    Öppna denna publikation i ny flik eller fönster >>Nutrition intervention goals from the perspectives of patients at risk of malnutrition: A qualitative study
    Visa övriga...
    2024 (Engelska)Ingår i: Journal of human nutrition and dietetics, ISSN 0952-3871, E-ISSN 1365-277X, Vol. 37, nr 1, s. 217-226Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Aims: Nutrition counselling is characterized by a collaborative approach whereby the patient and the dietitian establish goals that promote health and self-management.  Little is known about goal-setting in nutrition interventions of patients at risk of malnutrition. This study describes the perspectives and needs of patients at risk of malnutrition regarding goals of nutrition interventions.

    Methods: Semi-structured interviews were conducted with 15 patients from three primary care centres and one hospital in mid-Sweden. Interview transcripts were analysed using reflexive thematic analysis to identify themes and patterns in the data. 

    Results: Findings highlight that the participants rarely reflected on their personal goals of the nutrition intervention. Instead, they strived to maintain strength and energy, with the nutrition counselling being seen as supportive in managing nutrition impact symptoms. They described discrepancies between their perspectives and the dietitian’s regarding weight goals and the diet prescribed to gain weight.

    Conclusion: Elucidating patients’ goals is key to counteracting the discrepancies between the dietitians’ clinically oriented goals and patients’ perspectives. New strategies and tools that support collaborative goal-setting in nutrition interventions are needed to provide person-centred nutrition care.

    Ort, förlag, år, upplaga, sidor
    John Wiley & Sons, 2024
    Nyckelord
    Risk of malnutrition, goal-setting, shared decision-making, person-centred care, quali-tative research, nutrition intervention
    Nationell ämneskategori
    Näringslära
    Forskningsämne
    Kostvetenskap
    Identifikatorer
    urn:nbn:se:uu:diva-491137 (URN)10.1111/jhn.13246 (DOI)001075460200001 ()37794834 (PubMedID)
    Tillgänglig från: 2022-12-19 Skapad: 2022-12-19 Senast uppdaterad: 2024-05-07Bibliografiskt granskad
    Ladda ner fulltext (pdf)
    UUThesis_L-Al-Adili-2023
    Ladda ner (jpg)
    presentationsbild
  • 20.
    Al-Adili, Lina
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Boström, Anne‐Marie
    Department of Neurobiology, Care Science and Society Division of Nursing, Karolinska Institutet Huddinge Sweden;Theme Inflammation and Aging Karolinska University Hospital Huddinge Sweden;Research and Development Unit Stockholms Sjukhem Stockholm Sweden;Karolinska Institutet Huddinge Sweden.
    Orrevall, Ylva
    Department of Biosciences and Nutrition Karolinska Institute Stockholm Sweden;Medical Unit Clinical Nutrition Women's Health and Allied Health Professionals Theme, Karolinska University Hospital Stockholm Sweden.
    Lang, Nanna R.
    Department of Nutrition and Health VIA University College Denmark.
    Peersen, Charlotte
    Department of Unit for Service and Intern Control Department of Service and Quality, Trondheim Municipality Trondheim Norway.
    Persson, Inger
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Statistiska institutionen.
    Thoresen, Lene
    Cancer Clinic, St. Olavs Hospital Trondheim University Hospital Trondheim Norway.
    Lövestam, Elin
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Self‐reported documentation of goals and outcomes of nutrition care: A cross‐sectional survey study of Scandinavian dietitians2023Ingår i: Scandinavian Journal of Caring Sciences, ISSN 0283-9318, E-ISSN 1471-6712, Vol. 37, nr 2, s. 472-485Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background

    The documentation of goals and outcomes of nutrition care in Electronic Health Records is insufficient making further exploration of this of particular interest. Identifying common features in documentation practice among Scandinavian dietitians might provide information that can support improvement in this area.

    Aims

    To explore the associations between clinical dietitians' self-reported documentation of patients' goals and outcomes and demographic factors, self-reported implementation of the systematic framework the Nutrition Care Process 4th step (NCP) and its associated terminology, and factors associated with the workplace.

    Methods

    Data from a cross-sectional study based on a previously tested web-based survey (INIS) disseminated in 2017 to dietitians in Scandinavia (n = 494) was used. Respondents were recruited through e-mail lists, e-newsletters and social media groups for dietitians. Associations between countries regarding the reported documentation of goals and outcomes, implementation levels of the NCP 4th step, demographic information and factors associated with the workplace were measured through Chi-square test. Associations between dependent- and independent variables were measured through logistic regression analysis.

    Results

    Clinically practicing dietitians (n = 347) working in Scandinavia, Sweden (n = 249), Norway (n = 60), Denmark (n = 38), who had completed dietetic education participated. The reported documentation of goals and outcomes from nutrition intervention was highly associated with the reported implementation of NCP 4th step terminology (OR = 5.26; p = 0.009, OR = 3.56; p = 0.003), support from the workplace (OR = 4.0, p < 0.001, OR = 8.89, p < 0.001) and area of practice (OR = 2.02, p = 0.017). Years since completed dietetic training and educational level did not have any significant associations with documentation practice regarding goals and outcomes.

    Conclusion

    Findings highlight strong associations between the implementation of the NCP 4th step terminology and the documentation of goals and outcomes. Strategies to support dietitians in using standardized terminology and the development of tools for comprehensive documentation of evaluation of goals and outcome are required.

    Ladda ner fulltext (pdf)
    fulltext
  • 21.
    Al-Adili, Lina
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    McGreevy, Jenny
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centrum för klinisk forskning i Sörmland (CKFD). Nyköping Hosp, Dept Dietet, S-61185 Nyköping, Sweden..
    Orrevall, Ylva
    Karolinska Inst, Dept Biosci & Nutr, Stockholm, Sweden.;Karolinska Univ Hosp, Med Unit Clin Nutr, Womens Hlth & Allied Hlth Profess Theme, SE-17176 Stockholm, Sweden..
    Nydahl, Margaretha
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Bostrom, Anne-Marie
    Karolinska Inst, Div Nursing, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden.;Karolinska Univ Hosp, Theme Inflammat & Aging, Huddinge, Sweden.;Stockholms Sjukhem, Res & Dev Unit, Stockholm, Sweden..
    Lövestam, Elin
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Setting goals with patients at risk of malnutrition: A focus group study with clinical dietitians2022Ingår i: Patient Education and Counseling, ISSN 0738-3991, E-ISSN 1873-5134, Vol. 105, nr 7, s. 2103-2109Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: Setting goals collaboratively with patients is a key aspect in shared decision-making (SDM) in malnutrition interventions. The aim, therefore, was to gain an understanding of clinical dietitians' reflections regarding the process of goal-setting with patients at risk of malnutrition.

    Methods: Six semi-structured audio-recorded focus group discussions were held with registered dietitians (n = 29) from primary healthcare and hospitals in Sweden. Focus group transcripts were analysed thematically to find patterns in the data and identify themes.

    Results: Dietitians expressed striving to explore patients' narratives, capabilities, and resources before deciding on goals. They described different strategies in counseling patients and a lack of patient participation in the goal setting. They emphasized the difficulties of setting feasible goals due to discrepancies between their clinically oriented goals and patients' personal goals.

    Conclusion: Findings highlight a gap in the process of setting goals for patients at risk of malnutrition, where patients' participation was lacking. Education in SDM, and strategies and tools to support dietitians in involving patients in goal-setting, are required to bridge the gap and promote person-centeredness. Practice implications: Findings may be further used to develop tools and strategies, and design studies on the implementation of and education in SDM and goal-setting for malnutrition interventions.

    Ladda ner fulltext (pdf)
    fulltext
  • 22.
    Al-Adili, Lina
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Nordgren, Lena
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centrum för klinisk forskning i Sörmland (CKFD). Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Allmänmedicin och preventivmedicin. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Vårdvetenskap.
    Ylva, Orrevall
    McGreevy, Jenny
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centrum för klinisk forskning i Sörmland (CKFD). Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Lövestam, Elin
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Nutrition intervention goals from the perspectives of patients at risk of malnutrition: A qualitative study2024Ingår i: Journal of human nutrition and dietetics, ISSN 0952-3871, E-ISSN 1365-277X, Vol. 37, nr 1, s. 217-226Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Aims: Nutrition counselling is characterized by a collaborative approach whereby the patient and the dietitian establish goals that promote health and self-management.  Little is known about goal-setting in nutrition interventions of patients at risk of malnutrition. This study describes the perspectives and needs of patients at risk of malnutrition regarding goals of nutrition interventions.

    Methods: Semi-structured interviews were conducted with 15 patients from three primary care centres and one hospital in mid-Sweden. Interview transcripts were analysed using reflexive thematic analysis to identify themes and patterns in the data. 

    Results: Findings highlight that the participants rarely reflected on their personal goals of the nutrition intervention. Instead, they strived to maintain strength and energy, with the nutrition counselling being seen as supportive in managing nutrition impact symptoms. They described discrepancies between their perspectives and the dietitian’s regarding weight goals and the diet prescribed to gain weight.

    Conclusion: Elucidating patients’ goals is key to counteracting the discrepancies between the dietitians’ clinically oriented goals and patients’ perspectives. New strategies and tools that support collaborative goal-setting in nutrition interventions are needed to provide person-centred nutrition care.

    Ladda ner fulltext (pdf)
    fulltext
  • 23.
    Al-Adili, Lina
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Orrevall, Ylva
    McGreevy, Jenny
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centrum för klinisk forskning i Sörmland (CKFD). Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap. Department of Dietetics, Nyköping Hospital, Nyköping, Sweden.
    Nydahl, Margaretha
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Boström, Anne-Marie
    Lövestam, Elin
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Discrepancy in the evaluation of explicit and implicit nutrition care outcomes for patients at risk of malnutrition: A qualitative study2022Ingår i: Journal of human nutrition and dietetics, ISSN 0952-3871, E-ISSN 1365-277X, Vol. 35, nr 3, s. 494-503Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Nutrition care plays a significant role in the prevention and treatment of malnutrition, although the challenge to establish the precise impact of a nutrition intervention on patient outcomes remains. Malnutrition can be associated with diverse underlying diseases and an increased risk of complications, which increases the difficulty of monitoring and evaluating the nutrition intervention. The aim is to gain an understanding of dietitians' reflections concerning nutrition care outcomes of interventions in patients at risk of malnutrition.

    METHODS: Six semi-structured audio-recorded focus group discussions with registered dietitians from primary healthcare and hospitals (n = 29) in Sweden were held at the dietitians' place of work or at the University. Focus group transcripts were analysed thematically to reveal patterns in the data and identify themes and subthemes.

    RESULTS: The dietitians described an approach to nutrition monitoring and evaluation of patients at risk of malnutrition that was categorised into three themes: (i) quantitative explicit outcomes, based on objective measures and described as rigorous; (ii) quantitative estimated outcomes, based on estimates and described as less rigorous and (iii) qualitative implicit outcomes, based on patients' subjective perceptions and experiences of their health and described as difficult to measure.

    CONCLUSIONS: Findings indicate the need for new strategies to promote systematic and comprehensive nutrition monitoring and evaluation.

    Ladda ner fulltext (pdf)
    fulltext
  • 24.
    Alehagen, Urban
    et al.
    Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linköping University, 581 85, Linköping, Sweden.
    Alexander, J.
    Norwegian Institute of Public Health, 0403, Oslo, Norway.
    Aaseth, J.
    Research Department, Innlandet Hospital Trust, 2381, Brumunddal, Norway.
    Larsson, Anders
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Klinisk kemi.
    Lindahl, T. L.
    Division of Clinical Chemistry, Department of Experimental and Clinical Medicine, Linköping University, 581 85, Linköping, Sweden.
    Significant decrease of von Willebrand factor and plasminogen activator inhibitor-1 by providing supplementation with selenium and coenzyme Q10 to an elderly population with a low selenium status2020Ingår i: European Journal of Nutrition, ISSN 1436-6207, E-ISSN 1436-6215, Vol. 59, nr 8, s. 3581-3590Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    PURPOSE: Endothelial dysfunction and inflammation are conditions which fuel atherosclerosis and ischaemic heart disease. We have previously reported reduced cardiovascular (CV) mortality following supplementation with selenium and coenzyme Q10 to 443 elderly individuals with low selenium status (mean 67 μg/L) for 4 years. Here, we wanted to evaluate a possible association between the supplementation and the plasma concentrations of the von Willebrand factor (vWf), and the plasminogen activator inhibitor-1 (PAI-1), as they, besides other functions, are also strongly associated with endothelial function.

    METHODS: In this sub-study, 308 individuals (active substance: 157, placebo: 151) were included. Blood samples were drawn after 6 and 36 months and vWf and PAI-1 were determined in plasma by ELISA. Changes in concentrations of the biomarkers were evaluated by the use of T tests, repeated measures of variance, and ANCOVA analyses.

    RESULTS: The active treatment group presented a lower level of vWf after 36 months compared with the placebo group (1.08 U/mL vs. 5.10 U/mL; p = 0.0007). The results were validated through the repeated measures of variance evaluation. The PAI-1 levels showed an equally significant decrease in the active group (26.2 ng/mL vs. 49.2 ng/mL; p = 0.0002) and were also validated through repeated measures of variance evaluation.

    CONCLUSION: In this sub-study on elderly receiving selenium and coenzyme Q10, or placebo we found significantly lower levels of vWf and PAI-1 in the active treatment group as compared to the placebo group. We interpret this as a better endothelial function because of the intervention, which accords with a previous finding of reduced CV mortality.

    Ladda ner fulltext (pdf)
    fulltext
  • 25.
    Algethami, Jari S.
    et al.
    Najran Univ, Dept Chem, Coll Arts & Sci, POB 1988, Najran 11001, Saudi Arabia..
    Abd El-Wahed, Aida A.
    Agr Res Ctr, Plant Protect Res Inst, Dept Bee Res, Giza 12627, Egypt..
    Elashal, Mohamed H.
    Menoufia Univ, Dept Chem, Fac Sci, Shebin El Korn 32512, Egypt..
    Ahmed, Hanan R.
    Menoufia Univ, Dept Chem, Fac Sci, Shebin El Korn 32512, Egypt..
    Elshafiey, Esraa H.
    Menoufia Univ, Dept Chem, Fac Sci, Shebin El Korn 32512, Egypt..
    Omar, Eslam M.
    Assiut Univ, Plant Protect Dept, Fac Agr, Assiut 71526, Egypt..
    Al Naggar, Yahya
    Tanta Univ, Zool Dept, Fac Sci, Tanta 31527, Egypt.;Martin Luther Univ Halle Wittenberg, Inst Biol, Gen Zool, Hoher Weg 8, D-06120 Halle, Germany..
    Algethami, Ahmed F.
    Alnahalaljwal Fdn Saudi Arabia, POB 617, Mecca 21926, Saudi Arabia..
    Shou, Qiyang
    Zhejiang Chinese Med Univ, Clin Med Coll 2, Hangzhou 310053, Peoples R China..
    Alsharif, Sultan M.
    Taibah Univ, Biol Dept, Fac Sci, POB 887, Al Madinah, Saudi Arabia..
    Xu, Baojun
    BNU HKBU United Int Coll, Food Sci & Technol Program, Zhuhai 519087, Peoples R China..
    Shehata, Awad A.
    Univ Sadat City, Avian & Rabbit Dis Dept, Fac Vet Med, Menoufia 22857, Egypt.;PerNaturam GmbH, Trift 8, D-56290 Godenroth, Germany.;Prophy Inst Appl Prophylaxis, D-59159 Bonen, Germany..
    Guo, Zhiming
    Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Jiangsu, Peoples R China..
    Khalifa, Shaden A. M.
    Stockholm Univ, Wenner Gren Inst, Dept Mol Biosci, S-10691 Stockholm, Sweden..
    Wang, Kai
    Chinese Acad Agr Sci, Inst Apicultural Res, Beijing 100093, Peoples R China..
    El-Seedi, Hesham
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för läkemedelskemi, Farmakognosi. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för farmaceutisk biovetenskap. Menoufia Univ, Dept Chem, Fac Sci, Shebin El Korn 32512, Egypt.;Jiangsu Univ, Jiangsu Educ Dept, Int Joint Res Lab Intelligent Agr & Agri Prod Pro, Nanjing 210024, Peoples R China.;Jiangsu Univ, Int Res Ctr Food Nutr & Safety, Zhenjiang 212013, Jiangsu, Peoples R China..
    Bee Pollen: Clinical Trials and Patent Applications2022Ingår i: Nutrients, E-ISSN 2072-6643, Vol. 14, nr 14, artikel-id 2858Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Bee pollen is a natural cocktail of floral nectar, flower pollen, enzymes, and salivary secretions produced by honeybees. Bee pollen is one of the bee products most enriched in proteins, polysaccharides, polyphenols, lipids, minerals, and vitamins. It has a significant health and medicinal impact and provides protection against many diseases, including diabetes, cancer, infectious, and cardiovascular. Bee pollen is commonly promoted as a cost-effective functional food. In particular, bee pollen has been applied in clinical trials for allergies and prostate illnesses, with a few investigations on cancer and skin problems. However, it is involved in several patents and health recipes to combat chronic health problems. This review aimed to highlight the clinical trials and patents involving bee pollen for different cases and to present the role of bee pollen as a supplementary food and a potential product in cosmetic applications.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 26.
    Ali, Mohamed A.
    et al.
    Karolinska Inst, Novum, Dept Biosci & Nutr, Unit Publ Hlth Nutr, SE-14183 Huddinge, Sweden; Akershus Univ Coll, Fac Hlth Nutr & Management, Lillestrom, Norway.
    Yngve, Agneta
    Karolinska Inst, Dept Biosci & Nutr, S-10401 Stockholm, Sweden.
    Polyamines: dietary intake, database progress and food contribution to the total daily intake2009Ingår i: Annals of Nutrition and Metabolism, ISSN 0250-6807, E-ISSN 1421-9697, Vol. 55, s. 203-204Artikel i tidskrift (Övrigt vetenskapligt)
  • 27.
    Ali, Mohamed Atiya
    et al.
    Karolinska Inst, Novum, Dept Biosci & Nutr, Unit Publ Hlth Nutr, SE-14183 Huddinge, Sweden; Akershus Univ Coll, Fac Hlth Nutr & Management, Lillestrom, Norway.
    Poortvliet, Eric
    Show the Organization-Enhanced name(s).
    Stromberg, Roger
    Karolinska Inst, Novum, Dept Biosci & Nutr, SE-14183 Huddinge, Sweden.
    Yngve, Agneta
    Karolinska Inst, Dept Biosci & Nutr, S-10401 Stockholm, Sweden.
    Polyamines: total daily intake in adolescents compared to the intake estimated from the Swedish Nutrition Recommendations Objectified (SNO)2011Ingår i: Food & Nutrition Research, ISSN 1654-6628, E-ISSN 1654-661X, Vol. 55, s. 5455-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Dietary polyamines have been shown to give a significant contribution to the body pool of polyamines. Knowing the levels of polyamines (putrescine, spermidine, and spermine) in different foods and the contribution of daily food choice to polyamine intake is of interest, due to the association of these bioactive amines to health and disease. Objective: To estimate polyamine intake and food contribution to this intake in adolescents compared to a diet fulfilling the Swedish Nutrition Recommendations. Design: A cross-sectional study of dietary intake in adolescents and an 'ideal diet' (Swedish nutrition recommendations objectified [SNO]) list of foods was used to compute polyamine intake using a database of polyamine contents of foods. For polyamine intake estimation, 7-day weighed food records collected from 93 adolescents were entered into dietetic software (Dietist XP) including data on polyamine contents of foods. The content of polyamines in foods recommended according to SNO was entered in the same way. Results: The adolescents' mean daily polyamine intake was 316 +/- 170 mu mol/day, while the calculated contribution according to SNO was considerably higher with an average polyamine intake of 541 mu mol/day. In both adolescent's intake and SNO, fruits contributed to almost half of the total polyamine intake. The reason why the intake among the adolescents was lower than the one calculated from SNO was mainly due to the low vegetable consumption in the adolescents group. Conclusions: The average daily total polyamine intake was similar to that previously reported in Europe. With an 'ideal' diet according to Swedish nutrition recommendations, the intake of this bioactive non-nutrient would be higher than that reported by our adolescents and also higher than that previously reported from Europe.

  • 28.
    Ali, Mohamed Atiya
    et al.
    Karolinska Inst, Novum, Dept Biosci & Nutr, Unit Publ Hlth Nutr, SE-14183 Huddinge, Sweden; Akershus Univ Coll, Fac Hlth Nutr & Management, Lillestrom, Norway.
    Poortvliet, Eric
    Karolinska Inst, Novum, Dept Biosci & Nutr, Unit Publ Hlth Nutr, SE-14183 Huddinge, Sweden.
    Strömberg, Roger
    Karolinska Inst, Novum, Dept Biosci & Nutr, SE-14183 Huddinge, Sweden.
    Yngve, Agneta
    Karolinska Inst, Dept Biosci & Nutr, S-10401 Stockholm, Sweden.
    Polyamines in foods: development of a food database2011Ingår i: Food & Nutrition Research, ISSN 1654-6628, E-ISSN 1654-661X, Vol. 55, s. 5572-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Knowing the levels of polyamines (putrescine, spermidine, and spermine) in different foods is of interest due to the association of these bioactive nutrients to health and diseases. There is a lack of relevant information on their contents in foods. Objective: To develop a food polyamine database from published data by which polyamine intake and food contribution to this intake can be estimated, and to determine the levels of polyamines in Swedish dairy products. Design: Extensive literature search and laboratory analysis of selected Swedish dairy products. Polyamine contents in foods were collected using an extensive literature search of databases. Polyamines in different types of Swedish dairy products (milk with different fat percentages, yogurt, cheeses, and sour milk) were determined using high performance liquid chromatography (HPLC) equipped with a UV detector. Results: Fruits and cheese were the highest sources of putrescine, while vegetables and meat products were found to be rich in spermidine and spermine, respectively. The content of polyamines in cheese varied considerably between studies. In analyzed Swedish dairy products, matured cheese had the highest total polyamine contents with values of 52.3, 1.2, and 2.6 mg/kg for putrescine, spermidine, and spermine, respectively. Low fat milk had higher putrescine and spermidine, 1.2 and 1.0 mg/kg, respectively, than the other types of milk. Conclusions: The database aids other researchers in their quest for information regarding polyamine intake from foods. Connecting the polyamine contents in food with the Swedish Food Database allows for estimation of polyamine contents per portion.

  • 29.
    Alshahawy, Rasha
    et al.
    Univ Kafr Elshikh, Fac Med, Dept Physiol, Kafr Elshikh, Egypt..
    El Habachi, Nihal
    Alexandria Univ, Alexandria Clin Res Ctr, Alexandria, Egypt.;Univ Alexandria, Fac Med, Dept Physiol, Alexandria, Egypt..
    Allam, Eman
    Univ Alexandria, Fac Med, Dept Physiol, Alexandria, Egypt..
    Jernerén, Fredrik
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för farmaceutisk biovetenskap. Univ Oxford, Dept Pharmacol, Oxford, England..
    Refsum, Helga
    Univ Oxford, Dept Pharmacol, Oxford, England.;Univ Oslo, Inst Basic Med Sci, Dept Nutr, Oslo, Norway..
    Elshorbagy, Amany
    Univ Alexandria, Fac Med, Dept Physiol, Alexandria, Egypt.;Univ Oxford, Dept Pharmacol, Oxford, England..
    Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults2021Ingår i: Nutrition (Burbank, Los Angeles County, Calif.), ISSN 0899-9007, E-ISSN 1873-1244, Vol. 90, artikel-id 111306Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: The aim of this study was to examine the time scale of plasma fatty acid changes during transition to an exclusively plant- and fish-based diet in healthy individuals and determine whether there are associated alterations in arachidonic acid (ARA)-derived inflammatory mediators, estimated stearoyl coenzyme A desaturase (SCD) activity, and blood pressure. Methods: In pursuit of a religious fast, 36 adults abstained from eating poultry, meat, dairy products, and eggs, while increasing fish intake for 6 wk. Participants were assessed 1 wk before (W0) and 1 (WI) and 6 (W6) weeks after the diet change. Results: By W6, fasting plasma long-chain omega-3 polyunsaturated fatty acids (omega-3 LC-PUFAs); docosahexaenoic (DHA) and eicosapentaenoic (EPA) had increased (+67% and +73%, respectively; P <= 0.001), with early rise of DHA (+22%), but not EPA at W1.The omega-3 index (sum of DHA and EPA as a percent of total fatty acids) increased from 2.1% to 3.4%. ARA decreased progressively (W1, -9%; W6, -16%; P < 0.001). ARA precursors gamma-linolenic and dihomo-gamma-linolenic acids also decreased, without changes in the ARA-derived mediators prostaglandin-E2 and leukotriene-B4. Myristic acid decreased at W1 (-37%) and W6 (-40%). There was no consistent change in SCD indices. At W6, systolic and diastolic blood pressure had declined by 8 and 5 mm Hg, respectively (P <= 0.013). Conclusions: Shifting to a plant- and fish-based diet produces rapid and sustained increases in omega-3 LC-PUFAs and decreases the omega-6 PUFA ARA and its precursors, consistent with a cardio-protective profile. The rapid response suggests that these biomarkers may be useful for assessment of diet interventions. 

  • 30.
    Alsharari, Zayed
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Leander, Karin
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden..
    Sjögren, Per
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Carlsson, Axel
    Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Family Med & Primary Care, Stockholm, Sweden..
    Cederholm, Tommy
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    de Faire, Ulf
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden.;Karolinska Inst, Karolinska Univ Hosp, Dept Med, Cardiol Unit, Stockholm, Sweden..
    Hellenius, Mai-Lis
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden.;Karolinska Inst, Karolinska Univ Hosp, Dept Med, Cardiol Unit, Stockholm, Sweden..
    Marklund, Matti
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Risérus, Ulf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Association between carbohydrate intake and fatty acids in the de novo lipogenic pathway in serum phospholipids and adipose tissue in a population of Swedish men2020Ingår i: European Journal of Nutrition, ISSN 1436-6207, E-ISSN 1436-6215, Vol. 59, nr 5, s. 2089-2097Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose Fatty acid composition in blood and adipose tissue (AT) is a useful biomarker of dietary fat quality. However, circulating saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) have been proposed to also reflect carbohydrate-induced de novo lipogenesis (DNL) and stearoyl-CoA desaturase (SCD) activity. We aimed to test the hypothesis that high carbohydrate intake is related to SFA and MUFA in serum or AT in a Swedish population. Methods Fatty acid composition was measured in serum phospholipids (PL) and AT by gas chromatography in 63-year-old men (n = 299). Carbohydrate and alcohol intake was assessed (validated 7-day food records) in relation to total SFA, 16:0 (palmitate), 16:1 (palmitoleate), and estimated SCD activity (16:1n-7/16:0-ratio) in serum PL and in AT, respectively. Results Total carbohydrate intake was inversely associated with 16:0 in PL (P = 0.005), independently of BMI. Disaccharides were non-linearly (restricted cubic splines) and weakly associated with 16:1 and SCD activity in PL (nonlinear trend,P <= 0.02) but not AT. Carbohydrate intake and SCD expression were not associated (P >= 0.08,n = 81). Alcohol intake was, however, linearly associated with 16:0 in PL (P < 0.001), and with 16:1 (P < 0.001) and SCD activity (P <= 0.005) in both PL and AT. Conclusions Higher carbohydrate intake from sugar-rich foods or beverages was not clearly reflected by higher SFA or SCD activity in serum PL or AT. Alcohol was, however, associated with higher SFA and MUFA.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 31.
    Alsharari, Zayed
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Marklund, Matti
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Hellenius, Mai-Lis
    Karolinska Inst, Inst Environm Med, Cardiovasc Epidemiol Unit, S-10401 Stockholm, Sweden..
    Laguzzi, Federica
    Karolinska Inst, Inst Environm Med, Cardiovasc Epidemiol Unit, S-10401 Stockholm, Sweden..
    Gigante, Bruna
    Karolinska Inst, Inst Environm Med, Cardiovasc Epidemiol Unit, S-10401 Stockholm, Sweden..
    Leander, Karen
    Karolinska Inst, Inst Environm Med, Cardiovasc Epidemiol Unit, S-10401 Stockholm, Sweden..
    Sjögren, Per
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Cederholm, Tommy
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    de Faire, Ulf
    Karolinska Inst, Inst Environm Med, Cardiovasc Epidemiol Unit, S-10401 Stockholm, Sweden..
    Risérus, Ulf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Serum Biomarkers of Dietary Fatty Acids are Associated with Abdominal Obesity Measures in a Large Population-based Cohort of Men and Women2015Ingår i: The FASEB Journal, ISSN 0892-6638, E-ISSN 1530-6860, Vol. 29, nr 1 SupplementArtikel i tidskrift (Övrigt vetenskapligt)
  • 32.
    Alsharari, Zayed
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Risérus, Ulf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Leander, Karin
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden..
    Sjögren, Per
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Carlsson, Axel C.
    Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden..
    Vikstrom, Max
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden..
    Laguzzi, Federica
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden..
    Gigante, Bruna
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden.;Karolinska Inst, Danderyds Hosp, Div Cardiovasc Med, Dept Clin Sci, Stockholm, Sweden..
    Cederholm, Tommy
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    De Faire, Ulf
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Stockholm, Sweden.;Karolinska Univ Hosp, Karolinska Inst, Dept Med, Cardiol Unit, Stockholm, Sweden..
    Hellenius, Mai-Lis
    Karolinska Univ Hosp, Karolinska Inst, Dept Med, Cardiol Unit, Stockholm, Sweden..
    Marklund, Matti
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk nutrition och metabolism.
    Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women2017Ingår i: PLOS ONE, E-ISSN 1932-6203, Vol. 12, nr 1, artikel-id e0170684Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Abdominal obesity is a key contributor of metabolic disease. Recent trials suggest that dietary fat quality affects abdominal fat content, where palmitic acid and linoleic acid influence abdominal obesity differently, while effects of n-3 polyunsaturated fatty acids are less studied. Also, fatty acid desaturation may be altered in abdominal obesity. We aimed to investigate cross-sectional associations of serum fatty acids and desaturases with abdominal obesity prevalence in a population-based cohort study. Serum cholesteryl ester fatty acids composition was measured by gas chromatography in 60-year old men (n = 1883) and women (n = 2015). Cross-sectional associations of fatty acids with abdominal obesity prevalence and anthropometric measures (e.g., sagittal abdominal diameter) were evaluated in multivariable-adjusted logistic and linear regression models, respectively. Similar models were employed to investigate relations between desaturase activities (estimated by fatty acid ratios) and abdominal obesity. In logistic regression analyses, palmitic acid, stearoyl-CoA- desaturase and Delta 6-desaturase indices were associated with abdominal obesity; multivariable-adjusted odds ratios (95% confidence intervals) for highest versus lowest quartiles were 1.45 (1.19-1.76), 4.06 (3.27-5.05), and 3.07 (2.51-3.75), respectively. Linoleic acid, alpha-linolenic acid, docohexaenoic acid, and Delta 5-desaturase were inversely associated with abdominal obesity; multivariable-adjusted odds ratios (95% confidence intervals): 0.39 (0.32-0.48), 0.74 (0.61-0.89), 0.76 (0.62-0.93), and 0.40 (0.33-0.49), respectively. Eicosapentaenoic acid was not associated with abdominal obesity. Similar results were obtained from linear regression models evaluating associations with different anthropometric measures. Sex-specific and linear associations were mainly observed for n3-polyunsaturated fatty acids, while associations of the other exposures were generally non-linear and similar across sexes. In accordance with findings from short-term trials, abdominal obesity was more common among individuals with relatively high proportions of palmitic acid, whilst the contrary was true for linoleic acid. Further trials should examine the potential role of linoleic acid and its main dietary source, vegetable oils, in abdominal obesity prevention.

    Ladda ner fulltext (pdf)
    fulltext
  • 33.
    Amr, Alaa
    et al.
    Alexandria Univ, Fac Sci, Dept Zool, Alexandria 21568, Egypt..
    Abd El-Wahed, Aida
    Agr Res Ctr, Plant Protect Res Inst, Dept Bee Res, Giza 12627, Egypt..
    El-Seedi, Hesham
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för farmaceutisk biovetenskap. Jiangsu Univ, Int Res Ctr Food Nutr & Safety, Zhenjiang 212013, Peoples R China.;Jiangsu Univ, Jiangsu Educ Dept, Int Joint Res Lab Intelligent Agr & Agriprod Proc, Nanjing 210024, Peoples R China.;Menoufia Univ, Fac Sci, Dept Chem, Shibin Al Kawm 32512, Egypt..
    Khalifa, Shaden A. M.
    Stockholm Univ, Wenner Gren Inst, Dept Mol Biosci, S-10691 Stockholm, Sweden..
    Augustyniak, Maria
    Univ Siles Katowice, Inst Biol Biotechnol & Environm Protect, Fac Nat Sci, Bankowa 9, PL-40007 Katowice, Poland..
    El-Samad, Lamia M.
    Alexandria Univ, Fac Sci, Dept Zool, Alexandria 21568, Egypt..
    Abdel Karim, Ahmed E.
    Alexandria Univ, Fac Sci, Dept Zool, Alexandria 21568, Egypt..
    El Wakil, Abeer
    Alexandria Univ, Fac Educ, Dept Biol & Geol Sci, Alexandria, Egypt..
    UPLC-MS/MS Analysis of Naturally Derived Apis mellifera Products and Their Promising Effects against Cadmium-Induced Adverse Effects in Female Rats2023Ingår i: Nutrients, E-ISSN 2072-6643, Vol. 15, nr 1, artikel-id 119Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Honeybee products arouse interest in society due to their natural origin and range of important biological properties. Propolis (P) and royal jelly (RJ) attract scientists' attention because they exhibit antioxidant, anti-inflammatory, anti-bacterial, anti-tumor, and immunomodulatory abilities. In this study, we tested whether P and RJ could mitigate the adverse effects of cadmium (Cd) exposure, with particular emphasis on the reproductive function in female rats. In this line, one week of pretreatment was established. Six experimental groups were created, including (i) the control group (without any supplementation), (ii) the Cd group (receiving CdCl2 in a dose of 4.5 mg/kg/day), (iii) the P group (50 mg of P/kg/day), (iv) RJ group (200 mg of RJ/kg/day), (v) P + Cd group (rats pretreated with P and then treated with P and Cd simultaneously), (vi) RJ + Cd group (animals pretreated with RJ before receiving CdCl2 simultaneously with RJ). Cd treatment of rats adversely affected a number of measured parameters, including body weight, ovarian structure and ultrastructure, oxidative stress parameters, increased ovarian Cd content and prolonged the estrous cycle. Pretreatment and then cotreatment with P or RJ and Cd alleviated the adverse effects of Cd, transferring the clusters in the PCA analysis chart toward the control group. However, clusters for cotreated groups were still distinctly separated from the control and P, or RJ alone treated groups. Most likely, investigated honeybee products can alter Cd absorption in the gut and/or increase its excretion through the kidneys and/or mitigate oxidative stress by various components. Undoubtedly, pretreatment with P or RJ can effectively prepare the organism to overcome harmful insults. Although the chemical composition of RJ and P is relatively well known, focusing on proportion, duration, and scheme of treatment, as well as the effects of particular components, may provide interesting data in the future. In the era of returning to natural products, both P and RJ seem valuable materials for further consideration as anti-infertility agents.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 34. Anandavadivelan, Poorna
    et al.
    Wikman, Anna
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Reproduktiv hälsa.
    Malberg, Kalle
    Martin, Lena
    Rosenlund, Helen
    Rueb, Claudia
    Johar, Asif
    Lagergren, Pernilla
    Prevalence and intensity of dumping symptoms and their association with health-related quality of life following surgery for oesophageal cancer2021Ingår i: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983, Vol. 40, nr 3, s. 1233-1240Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND & AIMS: This study aimed to investigate the prevalence and intensity of symptoms of dumping syndrome (early and late) experienced by oesophageal cancer survivors one year after surgery and their association with health related quality of life (HRQL).

    METHODS: A prospective cohort study of patients who underwent surgery for oesophageal cancer in Sweden from January 2013 to April 2018, included at one year after surgery with follow-up at 1.5 years. Common symptoms of dumping syndrome were the exposure, classified as early and late onset, further divided into 'moderate' or 'severe' based on symptom intensity, and no dumping symptoms (reference group). The primary outcome was mean summary score of HRQL, and secondary outcomes were global quality of life, physical, role, emotional, cognitive and social function measured using the EORTC QLQ-C30 1.5 years after surgery. An ANCOVA model, adjusted for potential confounders was used to study the association between dumping symptoms and HRQL, presented as mean score differences (MD) with 95% confidence intervals (CI).

    RESULTS: Among 188 patients, moderate early dumping symptoms was experienced by 45% and severe early dumping by 9%. Moderate late dumping symptoms was reported by 13%, whereas 5% reported severe late dumping symptoms. Severe early dumping symptoms was associated with worse HRQL in 4 out of 7 aspects with worse global quality of life (MD -16, 95% CI: -27 to -4) and social function (MD -17, 95% CI: -32 to -3), which showed clinically large differences compared to having no such symptoms. Patients with moderate late dumping symptoms reported poorer HRQL in 6 out of 7 aspects compared to those with no dumping symptoms. Cognitive function (MD -27, 95% CI: -47 to -7) and emotional function (MD -24, 95% CI: -47 to -2) were significantly declined (clinically large relevance) in those with severe late dumping symptoms.

    CONCLUSIONS: Patients who have undergone curative treatment for oesophageal cancer experience reduced HRQL from early and late dumping symptoms at one year after surgery that indicate clear implications for clinical routine. Medical support and additional dietary counselling are required as potential ways to alleviate dumping symptoms on clinical repercussions.

    Ladda ner fulltext (pdf)
    fulltext
  • 35.
    Anandavadivelan, Poorna
    et al.
    Karolinska Inst, Karolinska Univ Hosp, Dept Mol Med & Surg, Surg Care Sci, S-17177 Stockholm, Sweden..
    Wikman, Anna
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Reproduktiv hälsa.
    Mälberg, Kalle
    Karolinska Inst, Karolinska Univ Hosp, Dept Mol Med & Surg, Surg Care Sci, S-17177 Stockholm, Sweden..
    Rosenlund, Helen
    Karolinska Inst, Karolinska Univ Hosp, Dept Mol Med & Surg, Surg Care Sci, S-17177 Stockholm, Sweden.;Danderyd Hosp, Div Clin Nutr & Dietet, Dept Orthoped, S-18288 Stockholm, Sweden..
    Johar, Asif
    Karolinska Inst, Karolinska Univ Hosp, Dept Mol Med & Surg, Surg Care Sci, S-17177 Stockholm, Sweden..
    Lagergren, Pernilla
    Karolinska Inst, Karolinska Univ Hosp, Dept Mol Med & Surg, Surg Care Sci, S-17177 Stockholm, Sweden.;Imperial Coll London, Dept Surg & Canc, London SW7 2AZ, England..
    Role of dietitian support in improving weight loss and nutrition impact symptoms after oesophageal cancer surgery2021Ingår i: European Journal of Clinical Nutrition, ISSN 0954-3007, E-ISSN 1476-5640, Vol. 75, s. 1134-1141Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Oesophageal cancer is frequently accompanied with malnutrition. We aimed to evaluate if early support from dietitians and patient's level of satisfaction with the support from dietitians are associated with better outcomes for weight loss and nutrition impact symptoms (NIS).

    Methods: A nationwide and prospective cohort study on patients operated for oesophageal cancer in Sweden from 2013 onwards, included one year after surgery. Study exposures were (1) preoperative dietitian support (yes vs no) and, (2) patient reported satisfaction with dietitian support (high vs low) and outcomes were postoperative (1) percentage weight loss and (2) NIS score (range 0-24); one year after surgery. An ANCOVA model adjusted for predefined confounders was used and presented as mean differences (MD) with 95% confidence intervals (CI).

    Results: Among 245 patients, as many as 57% had received preoperative dietitian support. Preoperative dietitian support was not associated with statistically significant differences in mean postoperative weight loss (MD 0.2 [95% CI -2.6 to 2.9]) and mean NIS score (MD 0.1 [95% CI: -0.8 to 1.0]). Likewise, satisfaction with the dietitian support was not associated with significant differences in mean postoperative weight loss (MD 1.4 [95% CI: -1.5 to 4.3]) and NIS score (MD -0.1 [95% CI: -1 to 0.8]).

    Conclusions: Long-term postoperative weight loss and NIS were not influenced based on whether dietitian support was initiated preoperatively or not and patient's satisfaction level with dietitian support. Similarity in results may reflect effective screening of malnutrition and dietitian support in centres treating oesophageal cancer in Sweden.

  • 36.
    Andersson, Agneta
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper.
    Dukat för prestation - recept och näringsguide för aktiva idrottare1996Övrigt (Övrigt vetenskapligt)
  • 37.
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Glykemiskt index: ett osäkert verktyg för idrottaren2009Ingår i: Nordisk nutrition, ISSN 1654-8337, nr 4, s. 21-23Artikel i tidskrift (Övrig (populärvetenskap, debatt, mm))
  • 38.
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Idrottsnutrition2013Ingår i: Näringslära för högskolan: Från grundläggande till avancerad nutrition, Stockholm: Liber AB , 2013, 6, s. 410-439Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
  • 39.
    Andersson, Agneta
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap. Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV).
    Idrottsnutrition2006Ingår i: Näringslära för högskolan, Liber AB, Stockholm , 2006, s. 394-423Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
  • 40.
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Kan vi räkna med fullkorn - i maten och i blodet?2009Ingår i: Dietistaktuellt, ISSN 1102-9285, nr 3, s. 15-17Artikel i tidskrift (Övrig (populärvetenskap, debatt, mm))
  • 41. Andersson, Agneta
    Kan vi räkna med fullkorn - maten och i blodet?2009Ingår i: Dietistaktuellt, Vol. XiX, nr 3, s. 15-17Artikel i tidskrift (Övrig (populärvetenskap, debatt, mm))
  • 42.
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Modedieter: till vilken nytta?2010Övrigt (Övrig (populärvetenskap, debatt, mm))
  • 43.
    Andersson, Agneta
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Näringslära som diciplin2013Ingår i: Näringslära för högskolan: Från grundläggande till avancerad nutrition, Stockholm: Liber AB , 2013, 6, , s. 11-16s. 11-16Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
  • 44.
    Andersson, Agneta
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Bakkman, Linda
    Berglund, Bo
    Reinebo, Peter
    Saltin, Bengt
    Kostrekommendationer för elitidrottare.: SOK:s kostpolicy för elitidrottare.2009Övrigt (Övrig (populärvetenskap, debatt, mm))
  • 45.
    Andersson, Agneta
    et al.
    Uppsala universitet, Medicinska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap. Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV).
    Göranzon, Helen
    Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för hushållsvetenskap (IHV).
    Energi- och metabolism2006Ingår i: Näringslära för högskolan, Liber AB, Stockholm , 2006, s. 166-193Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
  • 46.
    Andersson, Agneta
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Löf, Marie
    Karolinska Insitutet Stockholm.
    Energi och metabolism2013Ingår i: Näringslära för högskolan: Från grundläggande till avancerad nutrition., Stockholm: Liber AB , 2013, 6, s. 131-159Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
  • 47.
    Andersson, Agneta
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Marklund, Matti
    Department of Food Science; Swedish University of Argiculture Sciences, Uppsala.
    Diana, Mariana
    Department of Food Science; Swedish University of Argiculture Sciences, Uppsala.
    Landberg, Rikard
    Department of Food Science; Swedish University of Argiculture Sciences, Uppsala.
    Plasma Alkylresorcinol Concentrations Correlate with Whole Grain Wheat and Rye Intake and Show Moderate Reproducibility over a 2- to 3-Month Period in Free-Living Swedish Adults2011Ingår i: Journal of Nutrition, ISSN 0022-3166, E-ISSN 1541-6100, Vol. 141, nr 9, s. 1712-1718Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Plasma alkylresorcinols (AR) are useful as dietary biomarkers of wheat and rye whole grain (WG) during interventions but need to be validated in free-living populations. This study estimated the medium-term reproducibility and relative validity of plasma AR as biomarkers of WG and cereal fiber intake. Seventy-two Swedish adults kept 3-d weighed food records on 2 occasions 2-3 mo apart. Of these men and women, 51 provided a fasting blood sample at the end of each occasion. In addition, 18 participants provided 3 fasting and 3 nonfasting samples for 3 consecutive days on the first and second occasions, respectively. Dietary and blood variables did not differ between the 2 occasions. Nonfasting plasma total AR concentration [210 nmol/L (95% CI: 140, 314)] was higher than fasting [99 nmol/L (95% CI: 72, 137)] (P < 0.0001). Mean WG intake was 70 ± 61 g/d (41% from rye) and the intra-class correlation coefficient was 0.44 (95% CI: 0.26, 0.63) for total WG intake and 0.47 (95% CI: 0.27, 0.67) for the fasting plasma total AR concentration, suggesting moderate reproducibility. Fasting plasma total AR moderately correlated with WG rye + wheat (r(s) = 0.53; P < 0.001) and cereal fiber intake (r(s) = 0.32; P < 0.05) when using mean values from both occasions. This suggests that plasma AR concentration in fasting samples can be used as a biomarker of rye + wheat WG intake in free-living populations with a high and consistent WG intake.

  • 48.
    Andersson, Agneta
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Marklund, Matti
    Swedish Univ Agr Sci, Dept Food Sci, Uppsala, Sweden..
    Diana, Marina
    Swedish Univ Agr Sci, Dept Food Sci, Uppsala, Sweden..
    Landberg, Rikard
    Swedish Univ Agr Sci, Dept Food Sci, Uppsala, Sweden..
    Plasma Alkylresorcinol Concentrations Correlate with Whole Grain Wheat and Rye Intake and Show Moderate Reproducibility over a 2-to 3-Month Period in Free-Living Swedish Adults(1-3)2023Ingår i: Materials Science in Semiconductor Processing, ISSN 1369-8001, E-ISSN 1873-4081, Vol. 159, s. 1712-1718Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Plasma alkylresorcinols (AR) are useful as dietary biomarkers of wheat and rye whole grain (WG) during interventions but need to be validated in free-living populations. This study estimated the medium-term reproducibility and relative validity of plasma AR as biomarkers of WG and cereal fiber intake. Seventy-two Swedish adults kept 3-d weighed food records on 2 occasions 2-3 mo apart. Of these men and women, 51 provided a fasting blood sample at the end of each occasion. In addition, 18 participants provided 3 fasting and 3 nonfasting samples for 3 consecutive days on the first and second occasions, respectively. Dietary and blood variables did not differ between the 2 occasions. Nonfasting plasma total AR concentration [210 nmol/L (95% CI: 140, 314)] was higher than fasting [99 nmol/L (95% CI: 72, 137)] (P < 0.0001). Mean WG intake was 70 6 61 g/d (41% from rye) and the intra-class correlation coefficient was 0.44 (95% CI: 0.26, 0.63) for total WG intake and 0.47 (95% CI: 0.27, 0.67) for the fasting plasma total AR concentration, suggesting moderate reproducibility. Fasting plasma total AR moderately correlated with WG rye + wheat (rs = 0.53; P < 0.001) and cereal fiber intake (rs = 0.32; P < 0.05) when using mean values from both occasions. This suggests that plasma AR concentration in fasting samples can be used as a biomarker of rye + wheat WG intake in free-living populations with a high and consistent WG intake. J. Nutr. 141: 1712-1718, 2011.

    Ladda ner fulltext (pdf)
    fulltext
  • 49.
    Andersson, Agneta
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Martin, Lena
    Karolinska Institutet, Stockholm.
    Specialistkompetens - professionskvalitet och karriärsutveckling: Hur står vi oss gentemot övrig hälso- och sjukvårdspersonal?2018Ingår i: Dietistaktuellt, ISSN 1102-9285, Vol. XXVII, nr 4, s. 36-43Artikel i tidskrift (Övrig (populärvetenskap, debatt, mm))
  • 50.
    Andersson, Agneta
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för kostvetenskap.
    Nilsson, Gerd
    Kroppen, maten och generna2013Ingår i: Näringslära för högskolan: Från grundläggande till avancerad nutrition, Stockholm: Liber AB , 2013, 6, s. 17-36Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
1234567 1 - 50 av 774
RefereraExporteraLänk till träfflistan
Permanent länk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf