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  • 1.
    Anniko, Matti
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences.
    Arnold, W.
    Cytoskeletal proteins in human hair cells1995In: Acta oto-laryngologica. Supplementum, ISSN 0365-5237, E-ISSN 1651-2464, Vol. 519, p. 8-12Article in journal (Refereed)
    Abstract [en]

    Human cochlear and vestibular hair cells (HCs) were analysed for the three major cytoskeletal types of structures: microfilaments, microtubules, and intermediate filaments and several of their associated proteins. Specific immunomorphological features were identified: the apical surface, the infracuticular rod of F-actin, the cytoplasm and the HC bases and their interactions with adjacent supporting cells. There is morphological evidence for at least three functionally interacting units: the OHC as a cytoskeletal string interacting with the Deiter's cell, being a part of the rigid pancellular protein shell of the organ of Corti; compartmentalization of HCs (surrounded by rigid intermediate filament proteins in the supporting cells); and a calcium-guided short-loop feed-back control of type I HCs. The cytoskeletal composition of all four types of human HCs and their adjacent structures is similar to, although not identical with, corresponding compositions in other mammalian species.

  • 2. Nylén, CO
    et al.
    Erikson, L
    Herberts, G
    Södergren, V
    Tove, PA
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Solid State Electronics.
    An oto-micromanipulator1960In: Acta oto-laryngologica. Supplementum, ISSN 0365-5237, E-ISSN 1651-2464, Vol. 158, p. 304-Article in journal (Refereed)
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