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  • 1. Aapro, Matti
    et al.
    Beguin, Yves
    Birgegård, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Gascon, Pere
    Hedenus, Michael
    Österborg, Anders
    Too-Low Iron Doses and Too Many Dropouts in Negative Iron Trial?2011In: Journal of Clinical Oncology, ISSN 0732-183X, E-ISSN 1527-7755, Vol. 29, no 17, p. E525-E526Article in journal (Refereed)
  • 2. Aapro, Matti S.
    et al.
    Birgegård, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Bokemeyer, Carsten
    Cornes, Paul
    Foubert, Jan
    Gascon, Pere
    Glaspy, John
    Hellström-Lindberg, Eva
    Link, Hartmut
    Ludwig, Heinz
    Österborg, Anders
    Repetto, Lazzaro
    Soubeyran, Pierre
    Erythropoietins should be used according to guidelines2008In: The Lancet Oncology, ISSN 1470-2045, E-ISSN 1474-5488, Vol. 9, no 5, p. 412-3Article in journal (Refereed)
  • 3. Aardal, S
    et al.
    Aardal, NP
    Larsen, TH
    Angeletti, RH
    Stridsberg, M
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Taupenot, L
    Aunis, D
    Helle, KB
    Human pheochromocytoma: different patterns of catecholamine and chromogranins in the intact tumour, urine and serum in clinically unsuspected cases1996In: Scand J clin Lab Invest, Vol. 56, p. 511-Article in journal (Refereed)
  • 4.
    Aare, Sudhakar
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
    Ochala, Julien
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
    Norman, Holly S
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
    Radell, Peter
    Eriksson, Lars I
    Göransson, Hanna
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Chen, Yi-Wen
    Hoffman, Eric P
    Larsson, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
    Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model2011In: Physiological Genomics, ISSN 1094-8341, E-ISSN 1531-2267, Vol. 43, no 24, p. 1334-1350Article in journal (Refereed)
    Abstract [en]

    Acute quadriplegic myopathy (AQM) is a common debilitating acquired disorder in critically ill intensive care unit (ICU) patients which is characterized by tetraplegia/generalized weakness of limb and trunk muscles. Masticatory muscles, on the other hand, are typically spared or less affected, yet the mechanisms underlying this striking muscle-specific difference remain unknown. This study aims to evaluate physiological parameters and the gene expression profiles of masticatory and limb muscles exposed to factors suggested to trigger AQM, such as mechanical ventilation, immobilization, neuromuscular blocking agents (NMBA), corticosteroids (CS) and sepsis for five days by using a unique porcine model mimicking the ICU conditions. Single muscle fiber cross-sectional area and force-generating capacity, i.e., maximum force normalized to fiber cross-sectional area (specific force), revealed maintained masseter single muscle fiber cross-sectional area and specific-force after five days exposure to all triggering factors. This is in sharp contrast to observations in limb and trunk muscles, showing a dramatic decline in specific force in response to five days exposure to the triggering factors. Significant differences in gene expression were observed between craniofacial and limb muscles, indicating a highly complex and muscle specific response involving transcription and growth factors, heat shock proteins, matrix metalloproteinase inhibitor, oxidative stress responsive elements and sarcomeric proteins underlying the relative sparing of cranial versus spinal nerve innervated muscles during exposure to the ICU intervention.

  • 5.
    Aaseth, Jan
    et al.
    Faculty of Health and Social Sciences, Inland Norway University of Applied Sciences, N-2624 Lillehammer, Norway.
    Alexander, Jan
    Norwegian Institute of Public Health, P.O. Box 222, N-0213 Oslo, Norway.
    Alehagen, Urban
    Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linköping University, SE-581 85 Linköping, Sweden.
    Tinkov, Alexey
    IM Sechenov First Moscow State Medical University (Sechenov University), Bolshaya Pirogovskaya St., 2-4, 119146 Moscow, Russia.
    Skalny, Anatoly
    IM Sechenov First Moscow State Medical University (Sechenov University), Bolshaya Pirogovskaya St., 2-4, 119146 Moscow, Russia.
    Larsson, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Chemistry.
    Crisponi, Guido
    Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy.
    Nurchi, Valeria Marina
    Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy.
    The Aging Kidney-As Influenced by Heavy Metal Exposure and Selenium Supplementation2021In: Biomolecules, E-ISSN 2218-273X, Vol. 11, no 8, article id 1078Article in journal (Refereed)
    Abstract [en]

    The aging process in the kidneys has been well studied. It is known that the glomerular filtration rate (GFR) declines with age in subjects older than 50-60 years. However, there is still insufficient knowledge regarding the response of the aged kidney to environmental toxicants such as mercury, cadmium, and lead. Here, we present a review on the functional decline and proposed mechanisms in the aging kidney as influenced by metal pollutants. Due to the prevalence of these toxicants in the environment, human exposure is nearly unavoidable. Further, it is well known that acute and chronic exposures to toxic metals may be detrimental to kidneys of normal adults, thus it may be hypothesized that exposure of individuals with reduced GFR will result in additional reductions in renal function. Individuals with compromised renal function, either from aging or from a combination of aging and disease, may be particularly susceptible to environmental toxicants. The available data appear to show an association between exposure to mercury, cadmium and/or lead and an increase in incidence and severity of renal disease in elderly individuals. Furthermore, some physiological thiols, as well as adequate selenium status, appear to exert a protective action. Further studies providing improved insight into the mechanisms by which nephrotoxic metals are handled by aging kidneys, as well as possibilities of therapeutic protection, are of utmost importance.

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  • 6.
    Abalo, Xesus
    et al.
    Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Boije: Zebrafish Neuronal Networks. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical diabetology and metabolism.
    Lagman, David
    Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. Univ Bergen, Sars Int Ctr Marine Mol Biol, Bergen, Norway.
    Heras, Gabriel
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. Uppsala University, Science for Life Laboratory, SciLifeLab. Karolinska Inst, Dept Physiol & Pharmacol, Stockholm, Sweden.
    del Pozo, Ana
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Boije: Zebrafish Neuronal Networks. Uppsala University, Science for Life Laboratory, SciLifeLab.
    Eggert, Joel
    Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. Emory Univ, Dept Med, Atlanta, GA 30322 USA.
    Larhammar, Dan
    Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Larhammar: Pharmacology.
    Circadian regulation of phosphodiesterase 6 genes in zebrafish differs between cones and rods: Implications for photopic and scotopic vision2020In: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 166, p. 43-51Article in journal (Refereed)
    Abstract [en]

    A correlation is known to exist between visual sensitivity and oscillations in red opsin and rhodopsin gene expression in zebrafish, both regulated by the clock gene. This indicates that an endogenous circadian clock regulates behavioural visual sensitivity, apart from the regulation exerted by the pineal organ. However, the specific mechanisms for cones (photopic vision) and rods (scotopic vision) are poorly understood. In this work, we performed gene expression, cosinor and immunohistochemical analyses to investigate other key genes involved in light perception, encoding the different subunits of phosphodiesterase pde6 and transducin G alpha(T), in constant lighting conditions and compared to normal light-dark conditions. We found that cones display prominent circadian oscillations in mRNA levels for the inhibitory subunit gene pde6ha that could contribute to the regulation of photopic sensitivity by preventing overstimulation in photopic conditions. In rods, the mRNA levels of the inhibitory subunit gene pde6ga oscillate under normal conditions and dampen down in constant light but continue oscillating in constant darkness. There is an increase in total relative expression for pde6gb in constant conditions. These observations, together with previous data, suggest a complex regulation of the scotopic sensitivity involving endogenous and non-endogenous components, possibly present also in other teleost species. The G alpha(T) genes do not display mRNA oscillations and therefore may not be essential for the circadian regulation of photosensitivity. In summary, our results support different regulation for the zebrafish photopic and scotopic sensitivities and suggest circadian regulation of pde6ha as a key factor regulating photopic sensitivity, while the regulatory mechanisms in rods appear to be more complex.

  • 7. Abarca-Gómez, L.
    et al.
    Lind, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Cardiovascular epidemiology.
    Lytsy, Per
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Social Medicine.
    Sundström, Johan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Cardiology.
    Yngve, Agneta
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Food, Nutrition and Dietetics.
    Ezzati, M
    Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.2017In: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 390, no 10113, p. 2627-2642Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults.

    METHODS: We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants aged 5 years and older, including 31·5 million aged 5-19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5-19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity).

    FINDINGS: Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (-0·01 kg/m(2) per decade; 95% credible interval -0·42 to 0·39, posterior probability [PP] of the observed decrease being a true decrease=0·5098) in eastern Europe to an increase of 1·00 kg/m(2) per decade (0·69-1·35, PP>0·9999) in central Latin America and an increase of 0·95 kg/m(2) per decade (0·64-1·25, PP>0·9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0·09 kg/m(2) per decade (-0·33 to 0·49, PP=0·6926) in eastern Europe to an increase of 0·77 kg/m(2) per decade (0·50-1·06, PP>0·9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0·7% (0·4-1·2) in 1975 to 5·6% (4·8-6·5) in 2016 in girls, and from 0·9% (0·5-1·3) in 1975 to 7·8% (6·7-9·1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9·2% (6·0-12·9) in 1975 to 8·4% (6·8-10·1) in 2016 in girls and from 14·8% (10·4-19·5) in 1975 to 12·4% (10·3-14·5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22·7% (16·7-29·6) among girls and 30·7% (23·5-38·0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44-117) million girls and 117 (70-178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24-89) million girls and 74 (39-125) million boys worldwide were obese.

    INTERPRETATION: The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults.

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  • 8.
    Abbafati, Cristiana
    et al.
    Univ Roma La Sapienza, Dept Jurid & Econ Studies, Rome, Italy..
    Abbas, Kaja M.
    London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, London, England..
    Abbasi, Mohammad
    Hamadan Univ Med Sci, Dept Internal Med, Hamadan, Iran..
    Abbasifard, Mitra
    Rafsanjan Univ Med Sci, Clin Res Dev Unit, Rafsanjan, Iran.;Rafsanjan Univ Med Sci, Dept Internal Med, Rafsanjan, Iran..
    Abbasi-Kangevari, Mohsen
    Shahid Beheshti Univ Med Sci, Social Determinants Hlth Res Ctr, Tehran, Iran..
    Abbastabar, Hedayat
    Univ Tehran Med Sci, Adv Diagnost & Intervent Radiol Res Ctr, Tehran, Iran..
    Abd-Allah, Foad
    Cairo Univ, Dept Neurol, Cairo, Egypt..
    Abdelalim, Ahmed
    Cairo Univ, Dept Neurol, Cairo, Egypt..
    Abdollahi, Mohammad
    Univ Tehran Med Sci, Sch Pharm, Tehran, Iran.;Univ Tehran Med Sci, Inst Pharmaceut Sci TIPS, Tehran, Iran..
    Abdollahpour, Ibrahim
    Isfahan Univ Med Sci, Neurosci Res Ctr, Esfahan, Iran..
    Abedi, Aidin
    Univ Southern Calif, Dept Orthopaed Surg, Los Angeles, CA 90007 USA..
    Abedi, Parisa
    Iran Univ Med Sci, Sch Med, Tehran, Iran.;Harvard Univ, Neuroendocrine, Boston, MA 02115 USA..
    Abegaz, Kedir Hussein
    Near East Univ, Biostat Dept, Nicosia, Cyprus.;Madda Walabu Univ, Biostat & Hlth Informat, Bale Robe, Ethiopia..
    Abolhassani, Hassan
    Univ Tehran Med Sci, Res Ctr Immunodeficiencies, Tehran, Iran.;Karolinska Univ Hosp, Huddinge, Sweden..
    Abosetugn, Akine Eshete
    Debre Berhan Univ, Dept Publ Hlth, Debre Berhan, Ethiopia..
    Aboyans, Victor
    Dupuytren Univ Hosp, Dept Cardiol, Limoges, France.;Univ Limoges, Limoges, France..
    Abrams, Elissa M.
    Univ Manitoba, Sect Allergy & Clin Immunol, Winnipeg, MB, Canada.;Univ British Columbia, Dept Pediat, Vancouver, BC, Canada..
    Abreu, Lucas Guimaraes
    Univ Fed Minas Gerais, Dept Pediat Dent, Belo Horizonte, MG, Brazil..
    Abrigo, Michael R. M.
    Philippine Inst Dev Studies, Dept Res, Quezon City, Philippines..
    Abu Haimed, Abdulaziz Khalid
    Imam Abdulrahman Bin Faisal Univ, Dept Internal Med, Dammam, Saudi Arabia..
    Abualhasan, Ahmed
    Cairo Univ, Dept Neurol, Cairo, Egypt..
    Abu-Gharbieh, Eman
    Univ Sharjah, Dept Clin Sci, Sharjah, U Arab Emirates..
    Abu-Raddad, Laith Jamal
    Weill Cornell Med Coll Qatar, Dept Healthcare Policy & Res, Doha, Qatar..
    Abushouk, Abdelrahman I.
    Harvard Univ, Harvard Med Sch, Boston, MA 02115 USA.;Ain Shams Univ, Dept Med, Cairo, Egypt..
    Acebedo, Alyssa
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Ackerman, Ilana N.
    Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia..
    Adabi, Maryam
    Hamadan Univ Med Sci, Hamadan, Iran..
    Adair, Tim
    Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia..
    Adamu, Abdu A.
    Stellenbosch Univ, Dept Global Hlth, Cape Town, South Africa.;South African Med Res Council, Cochrane South Africa, Cape Town, South Africa..
    Adebayo, Oladimeji M.
    Univ Coll Hosp, Coll Med, Ibadan, Nigeria..
    Adedeji, Isaac Akinkunmi
    Olabisi Onabanjo Univ, Dept Sociol, Ago Iwoye, Nigeria..
    Adekanmbi, Victor
    Cardiff Univ, Sch Med, Cardiff, Wales..
    Adelson, Jaimie D.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Adeoye, Abiodun Moshood
    Univ Coll Hosp, Sch Lab Med & Sci, Ibadan, Nigeria.;Univ Ibadan, Inst Cardiovasc Dis, Ibadan, Nigeria..
    Adetokunboh, Olatunji O.
    Stellenbosch Univ, Ctr Excellence Epidemiol Modelling & Anal, Cape Town, South Africa.;Stellenbosch Univ, Dept Global Hlth, Cape Town, South Africa..
    Adham, Davoud
    Ardabil Univ Med Sci, Sch Hlth, Ardebil, Iran..
    Advani, Shailesh M.
    NIH, Social Behav Res Branch, Bldg 10, Bethesda, MD 20892 USA.;Georgetown Univ, Dept Oncol, Washington, DC USA..
    Afarideh, Mohsen
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran.;Mayo Clin, Dept Dermatol, Rochester, MN USA..
    Afshari, Mahdi
    Zabol Univ Med Sci, Dept Community Med, Zabol, Iran..
    Afshin, Ashkan
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Agardh, Emilie E.
    Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden..
    Agarwal, Gina
    McMaster Univ, Dept Family Med, Hamilton, ON, Canada..
    Agasthi, Pradyumna
    Mayo Clin, Dept Cardiovasc Med, Rochester, MN USA..
    Agesa, Kareha M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Aghaali, Mohammad
    Qom Univ Med Sci, Dept Epidemiol & Biostat, Qom, Iran..
    Aghamir, Seyed Mohammad Kazem
    Univ Tehran Med Sci, Urol Res Ctr, Tehran, Iran..
    Agrawal, Anurag
    CSIR, Inst Genom & Integrat Biol, Delhi, India.;Baylor Coll Med, Internal Med, Houston, TX 77030 USA..
    Ahmad, Tauseef
    Southeast Univ, Dept Epidemiol & Hlth Stat, Nanjing, Peoples R China..
    Ahmadi, Alireza
    Karolinska Inst, Dept Publ Hlth, Stockholm, Sweden.;Kermanshah Univ Med Sci, Dept Anesthesiol, Kermanshah, Iran..
    Ahmadi, Keivan
    Univ Nottingham, Lincoln Med Sch, Nottingham, England.;Univ Lincoln, Lincoln Med Sch, Lincoln, England..
    Ahmadi, Mehdi
    Ahvaz Jundishapur Univ Med Sci, Environm Hlth Engn, Ahwaz, Iran.;Ahvaz Jundishapur Univ Med Sci, Environm Technol Res Ctr, Ahwaz, Iran..
    Ahmadieh, Hamid
    Shahid Beheshti Univ Med Sci, Dept Ophthalmol, Tehran, Iran.;Shahid Beheshti Univ Med Sci, Ophthalm Res Ctr, Tehran, Iran..
    Ahmadpour, Ehsan
    Tabriz Univ Med Sci, Infect & Trop Dis Res Ctr, Tabriz, Iran..
    Ahmed, Muktar Beshir
    Jimma Univ, Dept Epidemiol, Jimma, Ethiopia.;Univ South Australia, Australian Ctr Precis Hlth, Adelaide, SA, Australia..
    Aji, Budi
    Jenderal Soedirman Univ, Fac Med & Publ Hlth, Purwokerto, Indonesia..
    Akalu, Temesgen Yihunie
    Univ Gondar, Dept Epidemiol & Biostat, Gondar, Ethiopia..
    Akinyemi, Rufus Olusola
    Univ Ibadan, Inst Adv Med Res & Training, Ibadan, Nigeria.;Newcastle Univ, Inst Neurosci, Newcastle Upon Tyne, Tyne & Wear, England..
    Akinyemiju, Tomi
    Duke Univ, Dept Populat Hlth Sci, Durham, NC USA.;Duke Univ, Duke Global Hlth Inst, Durham, NC USA..
    Akombi, Blessing
    Univ New South Wales, Sch Publ Hlth & Community Med, Sydney, NSW, Australia..
    Akunna, Chisom Joyqueenet
    Intercountry Ctr Oral Hlth ICOH Africa, Dept Publ Hlth, Jos, Nigeria.;Fed Minist Hlth, Dept Publ Hlth, Garki, Nigeria..
    Alahdab, Fares
    Mayo Clin Fdn Med Educ & Res, Mayo Evidencebased Practice Ctr, Rochester, MN USA..
    Al-Aly, Ziyad
    Washington Univ, John T Milliken Dept Internal Med, St Louis, MO 63110 USA.;Dept Vet Affairs, Clin Epidemiol Ctr, St Louis, MO USA..
    Alam, Khurshid
    Murdoch Univ, Murdoch Business Sch, Perth, WA, Australia..
    Alam, Noore
    Queensland Hlth, Prevent Div, Brisbane, Qld, Australia.;Griffith Univ, Ctr Environm & Populat Hlth, Nathan, Qld, Australia..
    Alam, Samiah
    Dalhousie Univ, Dept Community Hlth & Epidemiol, Halifax, NS, Canada..
    Alam, Tahiya
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Alanezi, Fahad Mashhour
    Imam Abdulrahman Bin Faisal Univ, Dammam, Saudi Arabia..
    Alanzi, Turki M.
    Imam Abdulrahman Bin Faisal Univ, Hlth Informat Management & Technol Dept, Dammam, Saudi Arabia..
    Albertson, Samuel B.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Alcalde-Rabanal, Jacqueline Elizabeth
    Natl Inst Publ Hlth, Ctr Hlth Syst Res, Cuernavaca, Morelos, Mexico..
    Alema, Niguse Meles
    Adigrat Univ, Dept Pharm, Adigrat, Ethiopia..
    Alemu, Biresaw Wassihun
    Arba Minch Univ, Coll Med & Hlth Sci, Arba Minch, Ethiopia.;Arba Minch Univ, Dept Midwifery, Arba Minch, Ethiopia..
    Alemu, Yihun Mulugeta
    Bahir Dar Univ, Dept Epidemiol & Biostat, Bahir Dar, Ethiopia..
    Alhabib, Khalid F.
    King Saud Univ, Dept Cardiac Sci, Riyadh, Saudi Arabia..
    Alhassan, Robert Kaba
    Univ Hlth & Allied Sci, Inst Hlth Res, Ho, Ghana..
    Ali, Muhammad
    Quaid I Azam Univ, Dept Biotechnol, Islamabad, Pakistan..
    Ali, Saqib
    Sultan Qaboos Univ, Coll Econ & Polit Sci, Dept Informat Syst, Muscat, Oman..
    Alicandro, Gianfranco
    Italian Natl Inst Stat, Directorate Social Stat & Populat Census, Rome, Italy..
    Alijanzadeh, Mehran
    Qazvin Univ Med Sci, Social Determinants Hlth Res Ctr, Qazvin, Iran..
    Alinia, Cyrus
    Urmia Univ Med Sci, Dept Hlth Care Management & Econ, Orumiyeh, Iran..
    Alipour, Vahid
    Iran Univ Med Sci, Hlth Econ Dept, Tehran, Iran.;Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, Iran..
    Alizade, Hesam
    Hormozgan Univ Med Sci, Infect & Trop Dis Res Ctr, Bandar Abbas, Iran..
    Aljunid, Syed Mohamed
    Kuwait Univ, Dept Hlth Policy & Management, Safat, Kuwait.;Natl Univ Malaysia, Int Ctr Casemix & Clin Coding, Bandar Tun Razak, Malaysia..
    Alla, Francois
    Univ Bordeaux, Bordeaux Sch Publ Hlth, Bordeaux, France..
    Allebeck, Peter
    Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden..
    Almadi, Majid Abdulrahman Hamad
    King Saud Univ, Coll Med, Riyadh, Saudi Arabia.;McGill Univ, Div Gastroenterol & Hepatol, Montreal, PQ, Canada..
    Almasi, Ali
    Kermanshah Univ Med Sci, Dept Environm Hlth Engn, Kermanshah, Iran..
    Almasi-Hashiani, Amir
    Arak Univ Med Sci, Dept Epidemiol, Arak, Iran..
    Almasri, Nihad A.
    Univ Jordan, Physiotherapy Dept, Amman, Jordan..
    Al-Mekhlafi, Hesham M.
    Jazan Univ, Med Res Ctr, Jazan, Saudi Arabia.;Sanaa Univ, Dept Parasitol, Sanaa, Yemen..
    Almulhim, Abdulaziz M.
    Imam Abdulrahman Bin Faisal Univ, Coll Med, Dammam, Saudi Arabia..
    Alonso, Jordi
    Pompeu Fabra Univ, Res Program Epidemiol & Publ Hlth, Barcelona, Spain.;Biomed Res Networking Ctr Epidemiol & Publ Hlth C, Dept Expt & Hlth Sci, Madrid, Spain..
    Al-Raddadi, Rajaa M.
    King Abdulaziz Univ, Dept Community Med, Jeddah, Saudi Arabia..
    Altirkawi, Khalid A.
    King Saud Univ, Pediat Intens Care Unit, Riyadh, Saudi Arabia..
    Alumran, Arwa Khalid
    Imam Abdulrahman Bin Faisal Univ, Hlth Informat Management & Technol Dept, Dammam, Saudi Arabia..
    Alvis-Guzman, Nelson
    Univ Cartagena, Hlth Econ Res Grp, Cartagena, Colombia.;Univ Costa, Res Grp Hosp Management & Hlth Policies, Barranquilla, Colombia..
    Alvis-Zakzuk, Nelson J.
    Univ Costa, Dept Econ Sci, Barranquilla, Colombia.;Natl Inst Hlth, Colombian Natl Hlth Observ, Bogota, Colombia..
    Amare, Azmeraw T.
    Bahir Dar Univ, Coll Med & Hlth Sci, Bahir Dar, Ethiopia.;Univ Adelaide, Sch Med, Adelaide, SA, Australia..
    Amare, Bekalu
    Mekelle Univ, Dept Pharmacol, Mekelle, Ethiopia..
    Amini, Saeed
    Arak Univ Med Sci, Hlth Serv Management Dept, Arak, Iran..
    Amini-Rarani, Mostafa
    Isfahan Univ Med Sci, Hlth Management & Econ Reasearch Ctr, Esfahan, Iran..
    Aminorroaya, Arya
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran.;Univ Tehran Med Sci, Tehran Heart Ctr, Tehran, Iran..
    Amiri, Fatemeh
    Kermanshah Univ Med Sci, Dept Radiol & Nucl Med, Kermanshah, Iran..
    Amit, Arianna Maever L.
    Univ Philippines Manila, Dept Epidemiol & Biostat, Manila, Philippines.;Johns Hopkins Univ, Sch Publ Hlth, Baltimore, MD USA..
    Amugsi, Dickson A.
    African Populat & Hlth Res Ctr, Maternal & Child Wellbeing, Nairobi, Kenya..
    Amul, Gianna Gayle Herrera
    Natl Univ Singapore, Lee Kuan Yew Sch Publ Policy, Singapore, Singapore..
    Anbesu, Etsay Woldu
    Samara Univ, Dept Publ Hlth, Samara, Ethiopia..
    Ancuceanu, Robert
    Carol Davila Univ Med & Pharm, Dept Pharm, Bucharest, Romania..
    Anderlini, Deanna
    Univ Queensland, Ctr Sensorimotor Performance, Brisbane, Qld, Australia.;Royal Brisbane & Womens Hosp, Dept Neurol, Brisbane, Qld, Australia..
    Anderson, Jason A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Andrei, Catalina Liliana
    Carol Davila Univ Med & Pharm, Dept Cardiol, Bucharest, Romania..
    Andrei, Tudorel
    Bucharest Univ Econ Studies, Dept Stat & Econometr, Bucharest, Romania..
    Androudi, Sofia
    Univ Thessaly, Dept Med, Volos, Greece..
    Angus, Colin
    Univ Sheffield, Sch Hlth & Related Res, Sheffield, S Yorkshire, England..
    Anjomshoa, Mina
    Rafsanjan Univ Med Sci, Social Determinants Hlth Res Ctr, Rafsanjan, Iran..
    Ansari, Fereshteh
    Tabriz Univ Med Sci, Res Ctr Evidence Based Med, Tabriz, Iran.;Agr Res Educ & Extens Org AREEO, Razi Vaccine & Serum Res Inst, Tehran, Iran..
    Ansari, Iman
    Shahed Univ, Med Students Res Comm, Tehran, Iran..
    Ansari-Moghaddam, Alireza
    Zahedan Univ Med Sci, Dept Epidemiol & Biostat, Zahedan, Iran..
    Antonazzo, Ippazio Cosimo
    Univ Milano Bicocca, Res Ctr Publ Hlth, Monza, Italy..
    Antonio, Carl Abelardo T.
    Univ Philippines Manila, Dept Hlth Policy & Adm, Manila, Philippines.;Hong Kong Polytech Univ, Dept Appl Social Sci, Hong Kong, Peoples R China..
    Antony, Catherine M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Antriyandarti, Ernoiz
    Sebelas Maret Univ, Agribusiness Study Program, Surakarta, Indonesia..
    Anvari, Davood
    Mazandaran Univ Med Sci, Dept Parasitol, Sari, Iran.;Iranshahr Univ Med Sci, Dept Parasitol, Iranshahr, Iran..
    Anwer, Razique
    Imam Mohammad Ibn Saud Islamic Univ, Dept Pathol, Riyadh, Saudi Arabia..
    Appiah, Seth Christopher Yaw
    Kwame Nkrumah Univ Sci & Technol, Dept Sociol & Social Work, Kumasi, Ghana.;Ludwig Maximilians Univ Munchen, Ctr Int Hlth, Munich, Germany..
    Arabloo, Jalal
    Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, Iran..
    Arab-Zozani, Morteza
    Birjand Univ Med Sci, Social Determinants Hlth Res Ctr, Birjand, Iran..
    Aravkin, Aleksandr Y.
    Univ Washington, Dept Appl Math, Seattle, WA 98195 USA.;Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Arba, Aseb Arba Kinfe
    Wolaita Sodo Univ, Dept Nursing, Wolaita Sodo, Ethiopia..
    Aremu, Olatunde
    Birmingham City Univ, Dept Publ Hlth, Birmingham, W Midlands, England..
    Ariani, Filippo
    Local Hlth Unit Tuscany Ctr, Reg Ctr Anal Data Occupat & Workrelated Injuries, Florence, Italy..
    Aripov, Timur
    Tashkent Inst Postgrad Med Educ, Publ Hlth & Healthcare Management, Tashkent, Uzbekistan.;Boston Childrens Hosp, Boston, MA USA..
    Armoon, Bahram
    Saveh Univ Med Sci, Social Determinants Hlth Res Ctr, Saveh, Iran.;Yasuj Univ Med Sci, Social Determinants Hlth Res Ctr, Yasuj, Iran..
    Arnlov, Johan
    Karolinska Inst, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden.;Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden..
    Arowosegbe, Oluwaseyi Olalekan
    Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, Basel, Switzerland.;Univ Basel, Dept Epidemiol & Publ Hlth, Basel, Switzerland..
    Aryal, Krishna K.
    Abt Associates Nepal, Monitoring Evaluat & Operat Res Project, Lalitpur, Nepal..
    Arzani, Afsaneh
    Babol Univ Med Sci, Sch Nursing & Midwifery, Babol, Iran.;Babol Univ Med Sci, Babol, Iran..
    Asaad, Malke
    Univ Texas Houston, Dept Plast Surg, Houston, TX USA..
    Asadi-Aliabadi, Mehran
    Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran..
    Asadi-Pooya, Ali A.
    Shiraz Univ Med Sci, Epilepsy Res Ctr, Shiraz, Iran.;Thomas Jefferson Univ, Dept Neurol, Philadelphia, PA 19107 USA..
    Asgari, Samaneh
    Shahid Beheshti Univ Med Sci, Prevent Metab Disorders Res Ctr, Tehran, Iran..
    Asghari, Babak
    Hamadan Univ Med Sci, Dept Microbiol, Hamadan, Iran..
    Jafarabadi, Mohammad Asghari
    Tabriz Univ Med Sci, Dept Biostat & Epidemiol, Tabriz, Iran.;Zanjan Univ Med Sci, Dept Biostat & Epidemiol, Zanjan, Iran..
    Ashbaugh, Charlie
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Assmus, Michael
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Atafar, Zahra
    Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran..
    Athari, Seyyed Shamsadin
    Zanjan Univ Med Sci, Dept Immunol, Zanjan, Iran..
    Atnafu, Desta Debalkie
    Bahir Dar Univ, Dept Hlth Syst & Hlth Econ, Bahir Dar, Ethiopia..
    Atout, Maha Moh'd Wahbi
    Philadelphia Univ, Fac Nursing, Amman, Jordan..
    Atre, Sachin R.
    Johns Hopkins Univ, Ctr Clin Global Hlth Educ, Baltimore, MD USA.;DY Patil Vidyapeeth, DY Patil Med Coll Hosp & Res Ctr, Pune, Maharashtra, India..
    Atteraya, Madhu Sudhan
    Keimyung Univ, Dept Social Welf, Daegu, South Korea..
    Ausloos, Floriane
    Univ Liege, Dept Gastroenterol, Liege, Belgium..
    Ausloos, Marcel
    Bucharest Univ Econ Studies, Dept Stat & Econometr, Bucharest, Romania.;Univ Leicester, Sch Business, Leicester, Leics, England..
    Avila-Burgos, Leticia
    Natl Inst Publ Hlth, Ctr Hlth Syst Res, Cuernavaca, Morelos, Mexico..
    Avokpaho, Euripide Frinel Gbenato Arthur
    Benin Clin Res Inst IRCB, Epidemiol & Clin Res, Abomey Calavi, Benin.;Fdn Sci Res FORS, Epidemiol & Clin Res, Cotonou, Benin..
    Quintanilla, Beatriz Paulina Ayala
    La Trobe Univ, Judith Lumley Ctr, Melbourne, Vic, Australia..
    Ayano, Getinet
    Curtin Univ, Sch Publ Hlth, Perth, WA, Australia..
    Ayanore, Martin Amogre
    Univ Hlth & Allied Sci, Dept Hlth Policy Planning & Management, Ho, Ghana..
    Aynalem, Getie Lake
    Univ Gondar, Dept Clin Midwifery, Gondar, Ethiopia..
    Aynalem, Yared Asmare
    Debre Berhan Univ, Dept Nursing, Debre Berhan, Ethiopia..
    Ayza, Muluken Altaye
    Mekelle Univ, Dept Pharmacol & Toxicol, Mekelle, Ethiopia..
    Azari, Samad
    Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, Iran..
    Azarian, Ghasem
    Hamadan Univ Med Sci, Dept Environm Hlth Engn, Hamadan, Iran..
    Azene, Zelalem Nigussie
    Univ Gondar, Dept Reprod Hlth, Gondar, Ethiopia..
    Azhar, Gulrez
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Azzopardi, Peter S.
    Burnet Inst, Global Adolescent Hlth Grp, Melbourne, Vic, Australia.;South Australian Hlth & Med Res Inst, Wardliparingga Aboriginal Res Unit, Adelaide, SA, Australia..
    Darshan, B. B.
    Babaee, Ebrahim
    Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran..
    Badawi, Alaa
    Publ Hlth Agcy Canada, Publ Hlth Risk Sci Div, Toronto, ON, Canada.;Univ Toronto, Dept Nutr Sci, Toronto, ON, Canada..
    Badiye, Ashish D.
    Govt Inst Forens Sci, Dept Forens Sci, Nagpur, Maharashtra, India..
    Bagherzadeh, Mojtaba
    Sharif Univ Technol, Dept Chem, Tehran, Iran..
    Bagli, Eleni
    Univ Hosp Ioannina, Dept Ophthalmol, Ioannina, Greece.;Fdn Res Technol, Inst Mol Biol & Biotechnol, Ioannina, Greece..
    Bahrami, Mohammad Amin
    Shiraz Univ Med Sci, Dept Healthcare Management & Educ, Shiraz, Iran..
    Baig, Atif Amin
    Sultan Zainal Abidin Univ, Biochem Unit, Kuala Terengganu, Malaysia..
    Bairwa, Mohan
    All India Inst Med Sci, Ctr Community Med, New Delhi, India..
    Bakhshaei, Mohammad Hossein
    Hamedan Univ Med Sci, Dept Anesthesiol, Hamadan, Iran..
    Bakhtiari, Ahad
    Univ Tehran Med Sci, Dept Hlth Policy Management & Econ, Tehran, Iran..
    Bakkannavar, Shankar M.
    Manipal Acad Higher Educ, Dept Forens Med & Toxicol, Mangalore, India..
    Balachandran, Arun
    Univ Groningen, Dept Demog, Groningen, Netherlands.;Inst Social & Econ Change, Populat Res Ctr, Bengaluru, India..
    Balakrishnan, Senthilkumar
    Haramaya Univ, Dept Med Microbiol, Harar, Ethiopia..
    Balalla, Shivanthi
    Auckland Univ Technol, Dept Psychol & Neurosci, Auckland, New Zealand..
    Balassyano, Shelly
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Baldasseroni, Alberto
    Local Hlth Author Florence, Dept Epidemiol, Florence, Italy..
    Ball, Kylie
    Deakin Univ, Inst Phys Act & Nutr, Burwood, Vic, Australia..
    Ballew, Shoshana H.
    Johns Hopkins Univ, Dept Epidemiol, Baltimore, MD USA..
    Balzi, Daniela
    USL Tuscany Ctr, Dept Prevent, Florence, Italy..
    Banach, Maciej
    Med Univ Lodz, Dept Hypertens, Lodz, Poland.;Polish Mothers Mem Hosp Res Inst, Lodz, Poland..
    Banerjee, Srikanta K.
    Walden Univ, Sch Hlth Sci, Minneapolis, MN USA..
    Banik, Palash Chandra
    Bangladesh Univ Hlth Sci, Dept Noncommunicable Dis, Dhaka, Bangladesh..
    Bannick, Marlena S.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Bante, Agegnehu Bante
    Arba Minch Univ, Dept Nursing, Arba Minch, Ethiopia..
    Bante, Simachew Animen
    Bahir Dar Univ, Dept Midwifery, Bahir Dar, Ethiopia..
    Baraki, Adhanom Gebreegziabher
    Univ Gondar, Dept Epidemiol & Biostat, Gondar, Ethiopia..
    Barboza, Miguel A.
    Costa Rican Dept Social Secur, Dept Neurosci, San Jose, Costa Rica.;Univ Costa Rica, Sch Med, San Pedro, Costa Rica..
    Barker-Collo, Suzanne Lyn
    Univ Auckland, Sch Psychol, Auckland, New Zealand..
    Barnighausen, Till Winfried
    Harvard Univ, TH Chan Sch Publ Hlth, Boston, MA 02115 USA.;Heidelberg Univ, Heidelberg Inst Global Hlth HIGH, Heidelberg, Germany..
    Barrero, Lope H.
    Pontifical Javeriana Univ, Dept Ind Engn, Bogota, Colombia..
    Barthelemy, Celine M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Barua, Lingkan
    Bangladesh Univ Hlth Sci, Dept Noncommunicable Dis, Dhaka, Bangladesh..
    Barzegar, Akbar
    Kermanshah Univ Med Sci, Dept Occupat Hlth Engn, Kermanshah, Iran..
    Basaleem, Huda
    Aden Coll, Sch Publ Hlth & Community Med, Aden, Yemen.;Int Ctr Diarrhoeal Dis Res, Maternal & Child Hlth Div, Dhaka, Bangladesh..
    Bassat, Quique
    Univ Barcelona, Barcelona Inst Global Hlth, Barcelona, Spain.;Catalan Inst Res & Adv Studies ICREA, Barcelona, Spain..
    Basu, Sanjay
    Harvard Univ, Ctr Primary Care, Boston, MA 02115 USA.;Imperial Coll London, Sch Publ Hlth, London, England..
    Baune, Bernhard T.
    Univ Munster, Dept Psychiat, Munster, Germany.;Melbourne Med Sch, Dept Psychiat, Melbourne, Vic, Australia..
    Bayati, Mohsen
    Shiraz Univ Med Sci, Hlth Human Resources Res Ctr, Shiraz, Iran..
    Baye, Bayisa Abdissa
    Ambo Univ, Dept Publ Hlth, Ambo, Ethiopia..
    Bazmandegan, Gholamreza
    Rafsanjan Univ Med Sci, Clin Res Dev Unit, Rafsanjan, Iran.;Rafsanjan Univ Med Sci, Dept Internal Med, Rafsanjan, Iran..
    Becker, Jacob S.
    Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27515 USA..
    Bedi, Neeraj
    Jazan Univ, Jazan, Saudi Arabia.;Gandhi Med Coll Bhopal, Dept Community Med, Bhopal, India..
    Beghi, Ettore
    Mario Negri Inst Pharmacol Res, Dept Neurosci, Milan, Italy..
    Behzadifar, Masoud
    Lorestan Univ Med Sci, Social Determinants Hlth Res Ctr, Khorramabad, Iran..
    Bejot, Yannick
    Univ Hosp Dijon, Dept Neurol, Dijon, France.;Univ Burgundy, Dijon Stroke Registry UFR Sci Sante, Dijon, France..
    Bekuma, Tariku Tesfaye Tesfaye
    Wollega Univ, Dept Publ Hlth, Nekemte, Ethiopia..
    Bell, Michelle L.
    Yale Univ, Sch Environm, New Haven, CT USA..
    Bello, Aminu K.
    Univ Alberta, Dept Med, Edmonton, AB, Canada..
    Bender, Rose G.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Bennett, Derrick A.
    Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England..
    Bennitt, Fiona B.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Bensenor, Isabela M.
    Univ Sao Paulo, Dept Internal Med, Sao Paulo, Brazil..
    Benziger, Catherine P.
    Essentia Hlth, Heart & Vasc Ctr, Duluth, MN USA..
    Berhe, Kidanemaryam
    Mekelle Univ, Dept Nutr & Dietet, Mekelle, Ethiopia..
    Berman, Adam E.
    Augusta Univ, Med Coll Georgia, Dept Med, Augusta, GA USA..
    Bernabe, Eduardo
    Kings Coll London, Fac Dent Oral & Craniofacial Sci, London, England..
    Bernstein, Robert S.
    Emory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA..
    Bertolacci, Gregory J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Bhagavathula, Akshaya Srikanth
    United Arab Emirates Univ, Dept Internal Med, Al Ain, U Arab Emirates.;Charles Univ Prague, Dept Social & Clin Pharm, Prague, Czech Republic..
    Bhageerathy, Reshmi
    Manipal Acad Higher Educ, Dept Hlth Informat Management, Mangalore, India.;Manipal Acad Higher Educ, Mangalore, India..
    Bhala, Neeraj
    Queen Elizabeth Hosp Birmingham, Inst Appl Hlth Res, Birmingham, W Midlands, England.;Queen Elizabeth Hosp Birmingham, Inst Translat Med, Birmingham, W Midlands, England.;Univ Birmingham, Inst Appl Hlth Res, Birmingham, W Midlands, England..
    Bhandari, Dinesh
    Univ Adelaide, Sch Publ Hlth, Adelaide, SA, Australia.;Tribhuvan Univ, Publ Hlth Res Lab, Kathmandu, Nepal..
    Bhardwaj, Pankaj
    All India Inst Med Sci, Dept Community Med & Family Med, Jodhpur, Rajasthan, India..
    Bhat, Anusha Ganapati
    Univ Massachusetts, Sch Med, Div Gen Internal Med, Springfield, MA USA..
    Bhattacharyya, Krittika
    Natl Inst Biomed Genom, Dept Stat & Computat Genom, Kalyani, W Bengal, India.;Univ Calcutta, Dept Stat, Kolkata, India..
    Bhattarai, Suraj
    Global Inst Interdisciplinary Studies, Dept Global Hlth, Kathmandu, Nepal..
    Bhutta, Zulfiqar A.
    Univ Toronto, Ctr Global Child Hlth, Toronto, ON, Canada.;Aga Khan Univ, Ctr Excellence Women & Child Hlth, Karachi, Pakistan..
    Bibi, Sadia
    Univ Agr Faisalabad, Inst Soil & Environm Sci, Faisalabad, Pakistan..
    Biehl, Molly H.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Bijani, Ali
    Babol Univ Med Sci, Social Determinants Hlth Res Ctr, Babol, Iran..
    Bikbov, Boris
    Mario Negri Inst Pharmacol Res, Milan, Italy..
    Bilano, Ver
    Creativ Ceut, Hlth Econ & Outcomes Res, London, England..
    Bin Sayeed, Muhammad Shahdaat
    Australian Natl Univ, Natl Ctr Epidemiol & Populat Hlth, Canberra, ACT, Australia.;Univ Dhaka, Dept Clin Pharm & Pharmacol, Dhaka, Bangladesh..
    Biondi, Antonio
    Univ Catania, Dept Gen Surg & Med Surg Specialties, Catania, Italy..
    Birihane, Binyam Minuye
    Ethiopian Publ Hlth Inst, Adis Ababa, Ethiopia.;Debre Tabor Univ, Dept Nursing, Debretabor, Ethiopia..
    Bisanzio, Donal
    Res Triangle Inst Int, Global Hlth Div, Res Triangle Pk, NC USA.;Univ Nottingham, Sch Med, Nottingham, England..
    Bisignano, Catherine
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Biswas, Raaj Kishore
    Univ New South Wales, Transport & Rd Safety TARS Res Ctr, Sydney, NSW, Australia..
    Bitew, Helen
    Mekelle Univ, Sch Pharm, Mekelle, Ethiopia..
    Bjorge, Tone
    Univ Bergen, Dept Global Publ Hlth & Primary Care, Bergen, Norway.;Canc Registry Norway, Oslo, Norway..
    Bockarie, Moses John
    European & Developing Countries Clin Trials Partn, Cape Town, South Africa.;Univ Cape Town, Dept Med, Cape Town, South Africa..
    Bohlouli, Somayeh
    Islamic Azad Univ, Dept Vet Med, Kermanshah, Iran..
    Bohluli, Mehdi
    Inst Adv Studies Basic Sci, Dept Comp Sci & Informat Technol, Zanjan, Iran.;Petanux Res GmBH, Dept Res & Innovat, Bonn, Germany..
    Bojia, Hunduma Amensisa
    Haramaya Univ, Sch Pharm, Harar, Ethiopia..
    Bolla, Srinivasa Rao
    Nazarbayev Univ, Dept Biomed Sci, Nur Sultan City, Kazakhstan..
    Boloor, Archith
    Manipal Acad Higher Educ, Dept Internal Med, Mangalore, India..
    Boon-Dooley, Alexandra S.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Borges, Guilherme
    Ramon de la Fuente Muniz Natl Inst Psychiat, Dept Epidemiol & Psychosocial Res, Mexico City, DF, Mexico..
    Borzi, Antonio Maria
    Univ Catania, Dept Clin & Expt Med, Catania, Italy..
    Borzouei, Shiva
    Hamadan Univ Med Sci, Dept Endocrinol, Hamadan, Iran..
    Bose, Dipan
    World Bank, Transport Global Practice, 1818 H St NW, Washington, DC 20433 USA..
    Bosetti, Cristina
    Mario Negri Inst Pharmacol Res, Dept Oncol, Milan, Italy..
    Boufous, Soufiane
    Univ New South Wales, Transport & Rd Safety TARS Res Ctr, Sydney, NSW, Australia..
    Bourne, Rupert
    Anglia Ruskin Univ, Vis & Eye Res Unit, Cambridge, England..
    Brady, Oliver J.
    London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, London, England..
    Braithwaite, Dejana
    Georgetown Univ, Div Hematol & Oncol, Washington, DC USA..
    Brauer, Michael
    Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Brayne, Carol
    Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England..
    Breitborde, Nicholas J. K.
    Ohio State Univ, Dept Psychol, Columbus, OH 43210 USA.;Ohio State Univ, Psychiat & Behav Hlth Dept, Columbus, OH 43210 USA..
    Breitner, Susanne
    Ludwig Maximilian Univ Munich, Inst Med Informat Proc Biometry & Epidemiol, Munich, Germany.;German Res Ctr Environm Hlth, Inst Epidemiol, Neuherberg, Germany..
    Brenner, Hermann
    German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany..
    Breusov, Alexey V.
    RUDN Univ, Inst Med, Moscow, Russia..
    Briant, Paul Svitil
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Briggs, Andrew M.
    Curtin Univ, Sch Physiotherapy & Exercise Sci, Perth, WA, Australia..
    Briko, Andrey Nikolaevich
    Bauman Moscow State Tech Univ, Dept Biomed Technol, Moscow, Russia..
    Briko, Nikolay Ivanovich
    IM Sechenov First Moscow State Med Univ, Dept Epidemiol & Evidence Based Med, Moscow, Russia..
    Britton, Gabrielle B.
    Inst Sci Res & High Technol Serv, Neurosci Unit, Panama City, Panama.;Gorgas Mem Inst Hlth Studies, Panama City, Panama..
    Brugha, Traolach
    Univ Leicester, Dept Hlth Sci, Leicester, Leics, England..
    Bryazka, Dana
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Buchbinder, Rachelle
    Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia.;Cabrini Inst, Cabrini Hosp, Monash Dept Clin Epidemiol, Melbourne, Vic, Australia..
    Bumgarner, Blair R.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Burkart, Katrin
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Burnett, Richard Thomas
    Hlth Canada, Populat Studies Div, Ottawa, ON, Canada..
    Nagaraja, Sharath Burugina
    Employee State Insurance Post Grad Inst Med Sci &, Dept Community Med, Bengalore, India..
    Busse, Reinhard
    Tech Univ Berlin, Dept Hlth Care Management, Berlin, Germany..
    Butt, Zahid A.
    Univ Waterloo, Sch Publ Hlth & Hlth Syst, Waterloo, ON, Canada.;Al Shifa Trust Eye Hosp, Al Shifa Sch Publ Hlth, Rawalpindi, Pakistan..
    Caetano dos Santos, Florentino Luciano
    Fed Polytech Sch Lausanne, Inst Microengn, Lausanne, Switzerland..
    Cahill, Leah E.
    Harvard Univ, Dept Nutr, Boston, MA 02115 USA.;Dalhousie Univ, Dept Med, Halifax, NS, Canada..
    Cahuana-Hurtado, Lucero
    Peruvian Univ Cayetano Heredia, Sch Publ Hlth & Adm, Lima, Peru..
    Cai, Tianji
    Univ Macau, Dept Sociol, Macau, Peoples R China..
    Callender, Charlton S. K. H.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Camera, Luis Alberto
    Hosp Italiano Buenos Aires, Dept Internal Med, Buenos Aires, DF, Argentina.;Argentine Soc Med, Board Directors, Buenos Aires, DF, Argentina..
    Campos-Nonato, Ismael R.
    Natl Inst Publ Hlth, Hlth & Nutr Res Ctr, Cuernavaca, Morelos, Mexico..
    Rincon, Julio Cesar Campuzano
    Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico.;Univ Valley Cuernavaca, Sch Med, Cuernavaca, Morelos, Mexico..
    Cao, Jackie
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Car, Josip
    Imperial Coll London, Dept Primary Care & Publ Hlth, London, England.;Nanyang Technol Univ, Ctr Populat Hlth Sci, Singapore, Singapore..
    Cardenas, Rosario
    Metropolitan Autonomous Univ, Dept Hlth Care, Mexico City, DF, Mexico..
    Carreras, Giulia
    Inst Canc Res Prevent & Clin Network, Florence, Italy..
    Carrero, Juan J.
    Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden..
    Carvalho, Felix
    Univ Porto, Res Unit Appl Mol Biosci UCIBIO, Porto, Portugal..
    Castaldelli-Maia, Joao Mauricio
    Univ Sao Paulo, Dept Psychiat, Sao Paulo, Brazil..
    Castaneda-Orjuela, Carlos A.
    Natl Inst Hlth, Colombian Natl Hlth Observ, Bogota, Colombia.;Univ Nacl Colombia, Epidemiol & Publ Hlth Evaluat Grp, Bogota, Colombia..
    Castelpietra, Giulio
    Univ Udine, Dept Med, Udine, Italy.;Healthcare Agcy Friuli Occidentale, Dept Mental Hlth, Pordenone, Italy..
    Castle, Chris D.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Castro, Emma
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Castro, Franz
    Gorgas Mem Inst Hlth Studies, Panama City, Panama..
    Catala-Lopez, Ferran
    Inst Hlth Carlos III, Natl Sch Publ Hlth, Madrid, Spain.;Ottawa Hosp Res Inst, Clin Epidemiol Program, Ottawa, ON, Canada..
    Causey, Kate
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Cederroth, Christopher R.
    Karolinska Inst, Dept Physiol & Pharmacol, Stockholm, Sweden.;Univ Nottingham, Natl Inst Hlth Res Nottingham Biomed Res Ctr, Nottingham, England..
    Cercy, Kelly M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Cerin, Ester
    Australian Catholic Univ, Mary MacKillop Inst Hlth Res, Melbourne, Vic, Australia.;Univ Hong Kong, Sch Publ Hlth, Hong Kong, Peoples R China..
    Chalek, Julian
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Chandan, Joht Singh
    Univ Birmingham, Inst Appl Hlth Res, Birmingham, W Midlands, England..
    Chang, Alex R.
    Geisinger Hlth Syst, Kidney Hlth Res Inst, Danville, PA USA..
    Chang, Angela Y.
    Univ Washington, Seattle, WA 98195 USA..
    Chang, Jung-Chen
    Natl Taiwan Univ, Coll Med, Taipei, Taiwan.;Natl Taiwan Univ Hosp, Dept Nursing, Taipei, Taiwan..
    Chang, Kai-Lan
    Univ Colorado, Cooperat Inst Res Environm Sci, Boulder, CO 80309 USA.;NOAA, Div Chem Sci, Earth Syst Res Lab, Boulder, CO USA..
    Charan, Jaykaran
    All India Inst Med Sci, Dept Pharmacol, Jodhpur, Rajasthan, India..
    Charlson, Fiona J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Queensland, Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia..
    Chattu, Vijay Kumar
    Univ Toronto, Dept Med, Toronto, ON, Canada..
    Chaturvedi, Sarika
    DY Patil Univ, Res Dept, Pune, Maharashtra, India..
    Cherbuin, Nicolas
    Australian Natl Univ, Res Sch Populat Hlth, Canberra, ACT, Australia..
    Chimed-Ochir, Odgerel
    Univ Occupat & Environm Hlth, Inst Ind Ecol Sci, Kitakyushu, Fukuoka, Japan..
    Chin, Ken Lee
    Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia.;Univ Melbourne, Melbourne Med Sch, Melbourne, Vic, Australia..
    Chirinos-Caceres, Jesus Lorenzo
    Cayetano Heredia Univ, Dept Publ Hlth Adm & Social Sci, Lima, Peru..
    Cho, Daniel Youngwhan
    Univ Washington, Div Plast Surg, Seattle, WA 98195 USA..
    Choi, Jee-Young Jasmine
    Seoul Natl Univ Hosp, Biomed Informat, Seoul, South Korea..
    Christensen, Hanne
    Univ Copenhagen, Bispebjerg Hosp, Copenhagen, Denmark..
    Chu, Dinh-Toi
    Hanoi Natl Univ Educ, Fac Biol, Hanoi, Vietnam..
    Chung, Michael T.
    Wayne State Univ, Dept Otolaryngol, Detroit, MI 48201 USA..
    Chung, Sheng-Chia
    UCL, Dept Hlth Informat, London, England.;Hlth Data Res UK, London, England..
    Cicuttini, Flavia M.
    Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia..
    Ciobanu, Liliana G.
    Univ South Australia, Sch Pharm & Med Sci, Adelaide, SA, Australia.;Univ Adelaide, Adelaide Med Sch, Adelaide, SA, Australia..
    Cirillo, Massimo
    Univ Naples Federico II, Dept Publ Hlth, Naples, Italy..
    Cislaghi, Beniamino
    London Sch Hyg & Trop Med, Dept Global Hlth & Dev, London, England..
    Classen, Thomas Khaled Dwayne
    North Rhine Westphalia NRW Ctr Hlth, Dept Key Quest & Int Cooperat, Bochum, Germany.;Bielefeld Univ, Bielefeld Sch Publ Hlth, Bielefeld, Germany..
    Cohen, Aaron J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Hlth Effects Inst, Boston, MA USA..
    Collins, Emma L.
    Univ Oxford, Nuffield Dept Med, Oxford, England..
    Comfort, Haley
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Compton, Kelly
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Conti, Sara
    Univ Milano Bicocca, Sch Med & Surg, Monza, Italy..
    Cooper, Owen R.
    Univ Colorado, Cooperat Inst Res Environm Sci, Boulder, CO 80309 USA.;NOAA, Chem Sci Lab, Boulder, CO USA..
    Corso, Barbara
    CNR, Inst Neurosci, Padua, Italy..
    Cortesi, Paolo Angelo
    Univ Milano Bicocca, Sch Med & Surg, Monza, Italy..
    Costa, Vera Marisa
    Univ Porto, Res Unit Appl Mol Biosci UCIBIO, Porto, Portugal..
    Cousin, Ewerton
    Univ Fed Rio Grande do Sul, Postgrad Program Epidemiol, Porto Alegre, RS, Brazil..
    Cowden, Richard G.
    Univ Free State, Dept Psychol, Park West, South Africa..
    Cowie, Benjamin C.
    Univ Melbourne, Dept Med, Melbourne, Vic, Australia.;Peter Doherty Inst Infect & Immun, WHO Collaborating Ctr Viral Hepatitis, Melbourne, Vic, Australia..
    Cromwell, Elizabeth A.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Croneberger, Andrew J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Cross, Di H.
    NIH, Off Director, Bldg 10, Bethesda, MD 20892 USA..
    Cross, Marita
    Univ Sydney, Fac Med & Hlth, Sydney, NSW, Australia..
    Crowe, Christopher Stephen
    Univ Washington, Div Plast & Reconstruct Surg, Seattle, WA 98195 USA..
    Cruz, Jessica A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Cummins, Steven
    London Sch Hyg & Trop Med, Dept Publ Hlth Environm & Soc, London, England..
    Cunningham, Matthew
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Dahlawi, Saad M. A.
    Imam Abdulrahman Bin Faisal Univ, Dept Environm Hlth, Dammam, Saudi Arabia..
    Dai, Haijiang
    Cent South Univ, Dept Cardiol, Changsha, Peoples R China.;York Univ, Dept Math & Stat, Toronto, ON, Canada..
    Dai, Hancheng
    Peking Univ, Coll Environm Sci & Engn, Beijing, Peoples R China..
    Damasceno, Albertino Antonio Moura
    Eduardo Mondlane Univ, Fac Med, Maputo, Mozambique..
    Damiani, Giovanni
    Univ Milan, IRCCS Ist Ortoped Galeazzi, Dermatol Clin, Milan, Italy.;Case Western Reserve Univ, Dept Dermatol, Cleveland, OH 44106 USA..
    D'Amico, Emanuele
    Univ Catania, Dept GF Ingrassia, Catania, Italy..
    Dandona, Lalit
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Publ Hlth Fdn India, Gurugram, India..
    Dandona, Rakhi
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Publ Hlth Fdn India, Gurugram, India..
    Daneshpajouhnejad, Parnaz
    Johns Hopkins Univ, Dept Pathol, Baltimore, MD USA..
    Dangel, William James
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Danielsson, Anna-Karin
    Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden..
    Gela, Jiregna Darega
    Ambo Univ, Dept Publ Hlth, Ambo, Ethiopia..
    Dargan, Paul I.
    Kings Coll London, Fac Life Sci & Med, London, England.;Guys & St Thomas NHS Fdn Trust, Dept Clin Toxicol, London, England..
    Darwesh, Aso Mohammad
    Univ Human Dev, Dept Informat Technol, Sulaymaniyah, Iraq..
    Daryani, Ahmad
    Mazandaran Univ Med Sci, Toxoplasmosis Res Ctr, Sari, Iran..
    Das, Jai K.
    Aga Khan Univ, Div Women & Child Hlth, Karachi, Pakistan..
    Das Gupta, Rajat
    Univ South Carolina, Dept Epidemiol & Biostat, Columbia, SC 29208 USA.;BRAC Univ, James P Grant Sch Publ Hlth, Dhaka, Bangladesh..
    Das Neves, Jose
    Univ Porto, Inst Res & Innovat Hlth, Porto, Portugal.;Univ Porto, Inst Biomed Engn INEB, Porto, Portugal..
    Dash, Aditya Prasad
    Cent Univ Tami Nadu, Thiruvarur, India..
    Davey, Gail
    Brighton & Sussex Med Sch, Dept Global Hlth & Infect, Brighton, E Sussex, England.;Addis Ababa Univ, Sch Publ Hlth, Addis Ababa, Ethiopia..
    Davila-Cervantes, Claudio Alberto
    Latin Amer Fac Social Sci Mexico, Dept Populat & Dev, Mexico City, DF, Mexico..
    Davis, Adrian C.
    Imperial Coll London, Dept Surg & Canc, London, England.;UCL, Ear Inst, London, England..
    Davitoiu, Dragos Virgil
    Carol Davila Univ Med & Pharm, Dept Gen Surg, Bucharest, Romania.;Clin Emergency Hosp Sf Pantelimon, Dept Surg, Bucharest, Romania..
    Davletov, Kairat
    Al Farabi Kazakh Natl Univ, Hlth Res Inst, Alma Ata, Kazakhstan..
    De Leo, Diego
    Griffith Univ, Australian Inst Suicide Res & Prevent, Nathan, Qld, Australia..
    De Neve, Jan-Walter
    Heidelberg Univ, Heidelberg Inst Global Hlth HIGH, Heidelberg, Germany..
    Dean, Frances E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    DeCleene, Nicole K.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Deen, Amanda
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Degenhardt, Louisa
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ New South Wales, Natl Drug & Alcohol Res Ctr, Sydney, NSW, Australia..
    DeLang, Marissa
    Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27515 USA..
    Dellavalle, Robert Paul
    Dept Vet Affairs, Dermatol Serv, St Louis, MO USA.;Univ Colorado Denver, Dept Dermatol, Aurora, CO USA..
    Demeke, Feleke Mekonnen
    Bahir Dar Univ, Dept Med Lab Sci, Bahir Dar, Ethiopia..
    Demoz, Gebre Teklemariam
    Aksum Univ, Sch Pharm, Aksum, Ethiopia..
    Demsie, Desalegn Getnet
    Adigrat Univ, Dept Pharm, Adigrat, Ethiopia..
    Denova-Gutierrez, Edgar
    Natl Inst Publ Hlth, Ctr Nutr & Hlth Res, Cuernavaca, Morelos, Mexico..
    Dereje, Nebiyu Dereje
    Addis Ababa Univ, Sch Publ Hlth, Addis Ababa, Ethiopia.;Wachemo Univ, Dept Publ Hlth, Hossana, Ethiopia..
    Deribe, Kebede
    Brighton & Sussex Med Sch, Wellcome Trust Brighton & Sussex Ctr Global Hlth, Brighton, E Sussex, England.;Addis Ababa Univ, Sch Publ Hlth, Addis Ababa, Ethiopia..
    Dervenis, Nikolaos
    Royal Liverpool Univ Hosp, St Pauls Eye Unit, Liverpool, Merseyside, England.;Aristotle Univ Thessaloniki, Dept Ophthalmol, Thessaloniki, Greece..
    Desai, Rupak
    Atlanta Vet Affairs Med Ctr, Div Cardiol, Decatur, GA USA..
    Desalew, Assefa
    Haramaya Univ, Sch Nursing & Midwifery, Harar, Ethiopia..
    Dessie, Getenet Ayalew
    Bahir Dar Univ, Dept Nursing, Bahir Dar, Ethiopia..
    Deuba, Keshab
    Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden.;Save Children, Natl Ctr AIDS & STD Control, Kathmandu, Nepal..
    Dharmaratne, Samath Dhamminda
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Peradeniya, Dept Community Med, Peradeniya, Sri Lanka..
    Dhungana, Govinda Prasad
    Far Western Univ, Dept Microbiol, Mahendranagar, Nepal..
    Dianatinasab, Mostafa
    Shiraz Univ Med Sci, Dept Epidemiol, Shiraz, Iran.;Shahroud Univ Med Sci, Dept Epidemiol & Biostat, Shahroud, Iran..
    da Silva, Diana Dias
    Univ Porto, Toxicol Lab, Porto, Portugal..
    Diaz, Daniel
    Univ Nacl Autonoma Mexico, Ctr Complex Sci, Mexico City, DF, Mexico.;Autonomous Univ Sinaloa, Fac Vet Med & Zootechn, Culiacan, Sinaloa, Mexico..
    Forooshani, Zahra Sadat Dibaji
    Univ Tehran Med Sci, Tehran, Iran..
    Dichgans, Martin
    Ludwig Maximilians Univ Munchen, Inst Stroke & Dementia Res, Munich, Germany..
    Didarloo, Alireza
    Urmia Univ Med Sci, Dept Publ Hlth, Orumiyeh, Iran..
    Dingels, Zachary V.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Dippenaar, Ilse N.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Dirac, M. Ashworth
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Swedish Family Med First Hill, Seattle, WA USA..
    Djalalinia, Shirin
    Minist Hlth & Med Educ, Dev Res & Technol Ctr, Tehran, Iran..
    Do, Hoa Thi
    Nguyen Tat Thanh Univ, Ctr Excellence Publ Hlth Nutr, Ho Chi Minh City, Vietnam..
    Dokova, Klara
    Med Univ Varna, Dept Social Med & Hlth Care Org, Varna, Bulgaria..
    Doku, David Teye
    Univ Cape Coast, Dept Populat & Hlth, Cape Coast, Ghana..
    Dolecek, Christiane
    Univ Oxford, Ctr Trop Med & Global Hlth, Oxford, England.;Mahidol Oxford Trop Med Res Unit, Bangkok, Thailand..
    Dolgert, Andrew J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Dorostkar, Fariba
    Iran Univ Med Sci, Fac Allied Med, Tehran, Iran..
    Doshi, Chirag P.
    Univ Southern Calif, Keck Sch Med, Los Angeles, CA 90007 USA..
    Doshi, Pratik P.
    Duke Univ, Sch Med, Durham, NC USA..
    Doshmangir, Leila
    Tabriz Univ Med Sci, Dept Hlth Policy & Management, Tabriz, Iran..
    Douiri, Abdel
    Kings Coll London, Sch Populat Hlth & Environm Sci, London, England..
    Doxey, Matthew C.
    Seattle Indian Hlth Board, Urban Indian Hlth Inst, Seattle, WA USA..
    Doyle, Kerrie E.
    Western Sydney Univ, Sch Med, Sydney, Vic, Australia.;RMIT Univ, Hlth Sci, Melbourne, Vic, Australia..
    Driscoll, Tim Robert
    Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW, Australia..
    Dubljanin, Eleonora
    Univ Belgrade, Inst Microbiol & Immunol, Belgrade, Serbia..
    Dunachie, Susanna J.
    Univ Oxford, Ctr Trop Med & Global Hlth, Oxford, England.;Mahidol Oxford Trop Med Res Unit, Bangkok, Thailand..
    Duncan, Bruce B.
    Univ Fed Rio Grande do Sul, Postgrad Program Epidemiol, Porto Alegre, RS, Brazil..
    Duraes, Andre Rodrigues
    Univ Fed Bahia, Sch Med, Salvador, BA, Brazil.;Escola Bahiana Med & Saude Publ, Dept Internal Med, Salvador, BA, Brazil..
    Eagan, Arielle Wilder
    Harvard Univ, Dept Global Hlth & Social Med, Boston, MA 02115 USA.;Tufts Med Ctr, Dept Social Serv, Boston, MA 02111 USA..
    Ebrahimi, Hedyeh
    Univ Tehran Med Sci, Liver & Pancreaticobilliary Dis Res Ctr, Tehran, Iran.;Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran..
    Kalan, Mohammad Ebrahimi
    Florida Int Univ, Dept Epidemiol, Miami, FL 33199 USA..
    Edvardsson, David
    La Trobe Univ, Sch Nursing & Midwifery, Melbourne, Vic, Australia.;Umeå Univ, Dept Nursing, Umeå, Sweden..
    Effiong, Andem
    Univ Newcastle, Ctr Clin Epidemiol & Biostat, Newcastle, NSW, Australia..
    Ehrlich, Joshua R.
    Univ Michigan, Dept Ophthalmol & Visual Sci, Ann Arbor, MI 48109 USA.;Univ Michigan, Inst Hlth Care Policy & Innovat, Ann Arbor, MI 48109 USA..
    El Nahas, Nevine
    Ain Shams Univ, Dept Neurol, Cairo, Egypt..
    El Sayed, Iman
    Alexandria Univ, Biomed Informat & Med Stat Dept, Alexandria, Egypt..
    Zaki, Maysaa El Sayed
    Mansoura Univ, Dept Clin Pathol, Mansoura, Egypt..
    El Tantawi, Maha
    Alexandria Univ, Pediat Dent & Dent Publ Hlth Dept, Alexandria, Egypt..
    Elbarazi, Iffat
    Abu Dhabi Univ, Dept Publ Hlth, Khalifa City, U Arab Emirates..
    Elgendy, Islam Y.
    Harvard Univ, Dept Cardiol, Boston, MA 02115 USA.;Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02114 USA..
    Elhabashy, Hala Rashad
    Cairo Univ, Dept Neurophysiol, Cairo, Egypt..
    El-Jaafary, Shaimaa I.
    Cairo Univ, Dept Neurol, Cairo, Egypt..
    Elsharkawy, Aisha
    Cairo Univ, Endem Med & Hepatogastroentrol Dept, Cairo, Egypt..
    Elyazar, Iqbal R. F.
    Eijkman Inst Mol Biol, Eijkman Oxford Clin Res Unit, Jakarta, Indonesia..
    Emamian, Mohammad Hassan
    Shahroud Univ Med Sci, Ophthalm Epidemiol Res Ctr, Shahroud, Iran..
    Emmons-Bell, Sophia
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Erskine, Holly E.
    Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia.;Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia..
    Eshrati, Babak
    Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran..
    Eskandari, Khalil
    Kerman Univ Med Sci, Dept Med Chem, Kerman, Iran.;Kerman Univ Med Sci, Pharmaceut Res Ctr, Kerman, Iran..
    Eskandarieh, Sharareh
    Univ Tehran Med Sci, Multiple Sclerosis Res Ctr, Tehran, Iran..
    Esmaeilnejad, Saman
    Islamic Azad Univ, Tehran Med Sci Branch, Kermanshah, Iran.;Tarbiat Modares Univ, Dept Physiol, Tehran, Iran..
    Esmaeilzadeh, Firooz
    Maragheh Univ Med Sci, Dept Publ Hlth, Maragheh, Iran..
    Esteghamati, Alireza
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran..
    Esteghamati, Sadaf
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran..
    Estep, Kara
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Etemadi, Arash
    NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA..
    Etisso, Atkilt Esaiyas
    Hawassa Univ, Unit Med Physiol, Hawassa, Ethiopia..
    Ezekannagha, Oluchi
    Int Inst Trop Agr, Ibadan, Nigeria..
    Fanzo, Jessica
    Johns Hopkins Univ, Sch Adv Int Studies, Baltimore, MD USA..
    Farag, Tamer
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Farahmand, Mohammad
    Univ Tehran Med Sci, Sch Publ Hlth, Tehran, Iran..
    Faraj, Anwar
    Univ Human Dev, Dept Polit Sci, Sulaymaniyah, Iraq..
    Faraon, Emerito Jose A.
    Univ Philippines Manila, Dept Hlth Policy & Adm, Manila, Philippines..
    Fareed, Mohammad
    Imam Mohammad Ibn Saud Islamic Univ, Coll Med, Riyadh, Saudi Arabia..
    Faridnia, Roghiyeh
    Mazandaran Univ Med Sci, Dept Med Parasitol, Sari, Iran..
    Farinha, Carla Sofia e Sa
    Natl Inst Stat, Disseminat Div, Lisbon, Portugal.;Directorate Gen Hlth DGS, Activ Planning & Control Unit, Lisbon, Portugal..
    Farioli, Andrea
    Univ Bologna, Dept Med & Surg Sci, Bologna, Italy..
    Faris, Pawan Sirwan
    Univ Pavia, Dept Biol & Biotechnol Lazzaro Spallanzani, Pavia, Italy.;Salahaddin Univ Erbil, Dept Biol, Erbil, Iraq..
    Faro, Andre
    Univ Fed Sergipe, Dept Psychol, Sao Cristovao, Brazil..
    Faruque, Mithila
    Bangladesh Univ Hlth Sci, Dept Noncommunicable Dis, Dhaka, Bangladesh..
    Farzadfar, Farshad
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran..
    Fattahi, Nazir
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Fazaeli, Ali Akbar
    Univ Tehran Med Sci, Dept Hlth Policy Management & Econ, Tehran, Iran..
    Fazlzadeh, Mehdi
    Univ Tehran Med Sci, Dept Environm Hlth Engn, Tehran, Iran.;Ardabil Univ Med Sci, Dept Environm Hlth Engn, Ardebil, Iran..
    Feigin, Valery L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Auckland Univ Technol, Natl Inst Stroke & Appl Neurosci, Auckland, New Zealand..
    Feldman, Rachel
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Fereshtehnejad, Seyed-Mohammad
    Karolinska Inst, Dept Neurobiol, Stockholm, Sweden.;Univ Ottawa, Div Neurol, Ottawa, ON, Canada..
    Fernandes, Eduarda
    Univ Porto, Associated Lab Green Chem LAQV, Porto, Portugal..
    Ferrara, Giannina
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Ferrara, Pietro
    Univ Milano Bicocca, Res Ctr Publ Hlth, Monza, Italy..
    Ferrari, Alize J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia..
    Ferreira, Manuela L.
    Univ Sydney, Inst Bone & Joint Res, Sydney, NSW, Australia..
    Feyissa, Garumma Tolu
    Jimma Univ, Dept Hlth Educ & Behav Sci, Jimma, Ethiopia..
    Filip, Irina
    Kaiser Permanente, Dept Psychiat, Fontana, CA USA.;AT Still Univ, Sch Hlth Sci, Mesa, AZ USA..
    Fischer, Florian
    Ravensburg Weingarten Univ Appl Sci, Inst Gerontol Hlth Serv & Nursing Res, Weingarten, Germany..
    Fisher, James L.
    Ohio State Univ, James Canc Hosp, Columbus, OH 43210 USA..
    Fitzgerald, Ryan
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Flohr, Carsten
    Kings Coll London, Unit Populat Based Dermatol Res, London, England..
    Flor, Luisa Sorio
    Sergio Arouca Natl Sch Publ Hlth, Rio De Janeiro, Brazil.;Univ Fed Espirito Santo, Vitoria, ES, Brazil..
    Foigt, Nataliya A.
    Natl Acad Med Sci Ukraine, Inst Gerontol, Kiev, Ukraine..
    Folayan, Morenike Oluwatoyin
    Obafemi Awolowo Univ, Dept Child Dent Hlth, Ife, Nigeria..
    Fomenkov, Artem Alekseevich
    Timiryazev Inst Plant Physiol, Dept Cell Biol & Biotechnol, Moscow, Russia..
    Force, Lisa M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;St Jude Childrens Res Hosp, Dept Global Pediat Med, 332 N Lauderdale St, Memphis, TN 38105 USA..
    Fornari, Carla
    Univ Milano Bicocca, Sch Med & Surg, Monza, Italy..
    Foroutan, Masoud
    Abadan Sch Med Sci, Abadan Fac Med Sci, Abadan, Iran..
    Fox, Jack T.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Francis, Joel Msafiri
    Univ Witwatersrand, Dept Family Med & Primary Care, Johannesburg, South Africa..
    Frank, Tahvi D.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Franklin, Richard Charles
    James Cook Univ, Coll Publ Hlth Med & Vet Sci, Douglas, Qld, Australia..
    Freitas, Marisa
    Univ Porto, Associated Lab Green Chem LAQV, Porto, Portugal..
    Fu, Weijia
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Fukumoto, Takeshi
    Kobe Univ, Dept Dermatol, Kobe, Hyogo, Japan..
    Fukutaki, Kai
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Fuller, John E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Fullman, Nancy
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Furtado, Joao M.
    Univ Sao Paulo, Div Ophthalmol, Sao Paulo, Brazil..
    Gad, Mohamed M.
    Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27515 USA.;Cleveland Clin, Dept Cardiovasc Med, Cleveland, OH 44106 USA..
    Gaidhane, Abhay Motiramji
    Datta Meghe Inst Med Sci, Dept Community Med, Wardha, India..
    Gakidou, Emmanuela
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Galles, Natalie C.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Gallus, Silvano
    Mario Negri Inst Pharmacol Res, Dept Environm Hlth Sci, Milan, Italy..
    Gamkrelidze, Amiran
    Natl Ctr Dis Control & Publ Hlth, Tbilisi, Georgia..
    Garcia-Basteiro, Alberto L.
    Manh Hlth Res Ctr CISM, Dept TB, Manhica, Mozambique.;Barcelona Inst Global Hlth, Viral & Bacterial Infect Res Program, Barcelona, Spain..
    Gardner, William M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Geberemariyam, Biniyam Sahiledengle
    Madda Walabu Univ, Dept Publ Hlth, Bale Robe, Ethiopia..
    Gebrehiwot, Abiyu Mekonnen
    Haramaya Univ, Dept Med Lab Sci, Harar, Ethiopia..
    Gebremedhin, Ketema Bizuwork
    Addis Ababa Univ, Dept Nursing & Midwifery, Addis Ababa, Ethiopia..
    Gebremeskel, Gebreamlak Gebremedhn
    Mekelle Univ, Dept Nursing, Mekelle, Ethiopia.;Aksum Univ, Dept Nursing, Aksum, Ethiopia..
    Gebremeskel, Leake G.
    Mekelle Univ, Dept Pharm, Mekelle, Ethiopia.;Aksum Univ, Sch Pharm, Aksum, Ethiopia..
    Gebresillassie, Begashaw Melaku
    Univ Gondar, Dept Clin Pharm, Gondar, Ethiopia.;Newcastle Univ, Sch Med & Publ Hlth, Newcastle Upon Tyne, Tyne & Wear, England..
    Gebreslassie, Assefa Ayalew Ayalew Ayalew
    Mekelle Univ, Dept Reprod Hlth, Mekelle, Ethiopia..
    Geramo, Yilma Chisha Dea
    Arba Minch Univ, Dept Publ Hlth, Arba Minch, Ethiopia..
    Geremew, Abraham
    Haramaya Univ, Dept Environm Hlth, Harar, Ethiopia..
    Hayoon, Anna Gershberg
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Gesesew, Hailay Abrha
    Mekelle Univ, Dept Epidemiol, Mekelle, Ethiopia.;Flinders Univ S Australia, Coll Med & Publ Hlth, Adelaide, SA, Australia..
    Gething, Peter W.
    Curtin Univ, Dept Publ Hlth, Perth, WA, Australia.;Telethon Kids Inst, Perth, WA, Australia..
    Gezae, Kebede Embaye
    Mekelle Univ, Dept Biostat, Mekelle, Ethiopia..
    Ghadimi, Maryam
    Johns Hopkins Univ, Dept Radiol & Radiol Sci, Baltimore, MD USA..
    Ghadiri, Keyghobad
    Kermanshah Univ Med Sci, Infect Dis Res Ctr, Kermanshah, Iran.;Kermanshah Univ Med Sci, Dept Pediat, Kermanshah, Iran..
    Ghaffarifar, Fatemeh
    Tarbiat Modares Univ, Dept Parasitol & Entomol, Tehran, Iran..
    Ghafourifard, Mansour
    Tabriz Univ Med Sci, Dept Med Surg Nursing, Tabriz, Iran..
    Ghajar, Alireza
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran..
    Ghamari, Farhad
    Arak Univ Med Sci, Dept Occupat Hlth, Arak, Iran..
    Ghashghaee, Ahmad
    Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, Iran.;Iran Univ Med Sci, Student Res Comm, Tehran, Iran..
    Ghiasvand, Hesam
    Univ Exeter, Inst Hlth Res, Exeter, Devon, England..
    Ghith, Nermin
    Tech Univ Denmark, Res Grp Genom Epidemiol, Copenhagen, Denmark..
    Gholamian, Asadollah
    Islamic Azad Univ, Dept Biol, Kermanshah, Iran.;Islamic Azad Univ, Young Researchers & Elite Club, Kermanshah, Iran..
    Ghosh, Rakesh
    Univ Calif San Francisco, Inst Global Hlth Sci, San Francisco, CA 94143 USA..
    Giampaoli, Simona
    Italian Natl Inst Hlth, Dept Cardiovasc Endocrine Metab Dis & Aging, Rome, Italy..
    Gilani, Syed Amir
    Univ Lahore, Fac Allied Hlth Sci, Lahore, Pakistan.;Afro Asian Inst, Lahore, Pakistan..
    Gill, Paramjit Singh
    Univ Warwick, Sch Med, Coventry, W Midlands, England..
    Gill, Tiffany K.
    Univ Adelaide, Adelaide Med Sch, Adelaide, SA, Australia..
    Gillum, Richard F.
    Howard Univ, Dept Community & Family Med, Washington, DC 20059 USA.;Howard Univ, Div Gen Internal Med, Washington, DC 20059 USA..
    Ginawi, Ibrahim Abdelmageed
    Minist Hlth, Family Med Res Ctr, Hail, Saudi Arabia..
    Ginindza, Themba G.
    Univ KwaZulu Natal, Discipline Publ Hlth Med, Durban, South Africa..
    Gitimoghaddam, Mojgan
    Univ British Columbia, Dept Pediat, Vancouver, BC, Canada..
    Giussani, Giorgia
    Mario Negri Inst Pharmacol Res, Lab Neurol Disorders, Milan, Italy..
    Glagn, Mustefa
    Arba Minch Univ, Dept Publ Hlth, Arba Minch, Ethiopia..
    Glushkova, Ekaterina Vladimirovna
    IM Sechenov First Moscow State Med Univ, Dept Epidemiol & Evidence Based Med, Moscow, Russia..
    Gnedovskaya, Elena V.
    Res Ctr Neurol, Dept Neurol 3, Moscow, Russia..
    Godinho, Myron Anthony
    Univ New South Wales, Sch Publ Hlth & Community Med, Sydney, NSW, Australia..
    Goharinezhad, Salime
    Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran..
    Golechha, Mahaveer
    Indian Inst Publ Hlth Gandhinagar, Hlth Syst & Policy Res, Gandhinagar, India..
    Goli, Srinivas
    Jawahar Lal Nehru Univ, Ctr Studies Reg Dev CSRD, New Delhi, India.;Univ Western Australia, Publ Policy Inst, Perth, WA, Australia..
    Gomez, Ricardo Santiago
    Univ Fed Minas Gerais, Dept Oral Surg & Pathol, Belo Horizonte, MG, Brazil..
    Gona, Philimon N.
    Univ Massachusetts Boston, Dept Exercise & Hlth Sci, Boston, MA USA..
    Gopalani, Sameer Vali
    Univ Oklahoma, Hlth Sci Ctr, Hudson Coll Publ Hlth, Oklahoma City, OK USA.;Govt Federated States Micronesia, Dept Hlth & Social Affairs, Palikir, Micronesia..
    Goren, Emily
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Gorini, Giuseppe
    Inst Canc Res Prevent & Clin Network, Oncol Network Prevent & Res Inst, Florence, Italy..
    Gorman, Taren M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Gottlich, Harrison Chase
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Goudarzi, Houman
    Hokkaido Univ, Ctr Environm & Hlth Sci, Sapporo, Hokkaido, Japan.;Hokkaido Univ, Dept Resp Med, Sapporo, Hokkaido, Japan..
    Goudarzian, Amir Hossein
    Mazandaran Univ Med Sci, Fac Nursing & Midwifery, Sari, Iran..
    Goulart, Alessandra C.
    Univ Sao Paulo, Ctr Clin & Epidemiol Res, Sao Paulo, Brazil.;Univ Sao Paulo, Dept Internal Med, Sao Paulo, Brazil..
    Goulart, Barbara Niegia Garcia
    Univ Fed Rio Grande do Sul, Postgrad Program Epidemiol, Porto Alegre, RS, Brazil..
    Grada, Ayman
    Boston Univ, Dept Dermatol, Boston, MA 02215 USA..
    Greaves, Felix
    Imperial Coll London, Dept Primary Care & Publ Hlth, London, England.;Publ Hlth England, Hlth Improvement Directorate, London, England..
    Grivna, Michal
    United Arab Emirates Univ, Inst Publ Hlth, Coll Med & Hlth Sci, Al Ain, U Arab Emirates.;Charles Univ Prague, Dept Publ Hlth & Prevent Med, Prague, Czech Republic..
    Grosso, Giuseppe
    Univ Catania, Dept Biomed & Biotechnol Sci, Catania, Italy..
    Gubari, Mohammed Ibrahim Mohialdeen
    Univ Sulaimani, Dept Family & Community Med, Sulaimani, Iraq..
    Gudi, Nachiket
    Manipal Acad Higher Educ, Dept Hlth Policy, Mangalore, India..
    Gugnani, Harish Chander
    St James Sch Med, Dept Epidemiol, The Valley, Anguilla.;St James Sch Med, Dept Microbiol, The Valley, Anguilla..
    Guimaraes, Andre Luiz Sena
    Univ Estadual Montes Claros, Sch Dent, Montes Claros, MG, Brazil..
    Guimaraes, Rafael Alves
    Univ Fed Goias, Inst Trop Pathol & Publ Hlth IPTSP, Goiania, Go, Brazil..
    Guled, Rashid Abdi
    Jigjiga Univ, Coll Med & Hlth Sci, Jijiga, Ethiopia..
    Gultie, Teklemariam
    Arba Minch Univ, Dept Midwifery, Arba Minch, Ethiopia..
    Guo, Gaorui
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Guo, Yuming
    Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia.;Binzhou Med Univ, Dept Epidemiol, Yantai, Peoples R China. Mahatma Gandhi Inst Med Sci, Dept Community Med, Sevagram, India..
    Gupta, Rahul
    Eternal Heart Care Ctr & Res Inst, Dept Prevent Cardiol, Jaipur, Rajasthan, India.;March Dimes, Med Resources, Arlington, VA USA..
    Gupta, Rajeev
    Mahatma Gandhi Univ Med Sci, Dept Med, Jaipur, Rajasthan, India.;West Virginia Univ, Sch Publ Hlth, Hlth Policy Management & Leadership, Morgantown, WV 26506 USA..
    Sharan, Subodh
    Gupta, Tarun
    Indian Inst Technol Kanpur, Dept Civil Engn, Kanpur, Uttar Pradesh, India..
    Haagsma, Juanita A.
    Erasmus MC, Dept Publ Hlth, Rotterdam, Netherlands..
    Hachinski, Vladimir
    Univ Western Ontario, Clin Neurol Sci, London, ON, Canada.;Lawson Hlth Res Inst, London, ON, Canada..
    Haddock, Beatrix
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Hafezi-Nejad, Nima
    Univ Tehran Med Sci, Sch Med, Tehran, Iran.;Johns Hopkins Univ, Dept Radiol & Radiol Sci, Baltimore, MD USA..
    Hafiz, Abdul
    London Sch Hyg & Trop Med, Epidemiol Programme, London, England.;Umm AL Qura Univ, Coll Med, Mecca, Saudi Arabia..
    Hagins, Hailey
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Haile, Lydia M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Haile, Teklehaimanot Gereziher
    Aksum Univ, Dept Nursing, Aksum, Ethiopia..
    Haj-Mirzaian, Arvin
    Shahid Beheshti Univ Med Sci, Obes Res Ctr, Tehran, Iran.;Univ Tehran Med Sci, Dept Pharmacol, Tehran, Iran.;Johns Hopkins Univ, Dept Radiol & Radiol Sci, Baltimore, MD USA..
    Haj-Mirzaian, Arya
    Hall, Brian J.
    Univ Macau, Dept Psychol, Macau, Peoples R China..
    Halvaei, Iman
    Tarbiat Modares Univ, Dept Anat Sci, Tehran, Iran..
    Hamadeh, Randah R.
    Arabian Gulf Univ, Dept Family & Community Med, Manama, Bahrain..
    Abdullah, Kanaan Hamagharib
    Univ Human Dev, Coll Law & Polit Sci, Sulaymaniyah, Iraq..
    Hameed, Sajid
    Univ Lahore, Univ Inst Publ Hlth, Lahore, Pakistan..
    Hamidi, Samer
    Hamdan Bin Mohammed Smart Univ, Sch Hlth & Environm Studies, Dubai, U Arab Emirates..
    Hamilton, Erin B.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Hammer, Melanie S.
    Washington Univ, Dept Energy Environm & Chem Engn, St Louis, MO 63110 USA.;Dalhousie Univ, Dept Phys & Atmospher Sci, Halifax, NS, Canada..
    Han, Chieh
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Han, Hannah
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Handiso, Demelash Woldeyohannes
    Wachemo Univ, Dept Publ Hlth, Hossana, Ethiopia..
    Hanif, Asif
    Univ Lahore, Univ Inst Publ Hlth, Lahore, Pakistan..
    Hankey, Graeme J.
    Univ Western Australia, Sch Med, Perth, WA, Australia.;Sir Charles Gairdner Hosp, Dept Neurol, Perth, WA, Australia..
    Haririan, Hamidreza
    Tabriz Univ Med Sci, Tabriz, Iran..
    Haro, Josep Maria
    Univ Barcelona, Res Unit, Barcelona, Spain.;Biomed Res Networking Ctr Mental Hlth Network Cib, Barcelona, Spain..
    Harvey, James D.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Hasaballah, Ahmed I.
    Al Azhar Univ, Dept Zool & Entomol, Cairo, Egypt..
    Hasan, Md Mehedi
    Univ Queensland, ARC Ctr Excellence Children & Families Life Cours, Brisbane, Qld, Australia.;Univ Queensland, Social Sci Res Inst, Brisbane, Qld, Australia..
    Hasanpoor, Edris
    Maragheh Univ Med Sci, Dept Healthcare Management, Maragheh, Iran..
    Hasanzadeh, Amir
    Univ Tehran Med Sci, Dept Microbiol, Tehran, Iran.;Maragheh Univ Med Sci, Dept Microbiol, Maragheh, Iran..
    Hashemian, Maryam
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran.;Utica Coll, Dept Biol, Utica, NY 13502 USA..
    Hashi, Abdiwahab
    Jigjiga Univ, Dept Publ Hlth, Jijiga, Ethiopia..
    Hassan, Amr
    Cairo Univ, Dept Neurol, Cairo, Egypt..
    Hassan, Shoaib
    Univ Bergen, Ctr Int Hlth CIH, Bergen, Norway.;Univ Bergen, Bergen Ctr Eth & Prior Setting BCEPS, Bergen, Norway..
    Hassanipour, Soheil
    Guilan Univ Med Sci, Caspian Digest Dis Res Ctr, Rasht, Iran.;Guilan Univ Med Sci, Gastrointestinal & Liver Dis Res Ctr, Rasht, Iran..
    Hassankhani, Hadi
    Tabriz Univ Med Sci, Sch Nursing & Midwifery, Tabriz, Iran..
    Havmoeller, Rasmus J.
    Skaane Cty Council, Skaane Univ Hosp, Malmö, Sweden..
    Hay, Roderick J.
    Kings Coll London, St Johns Inst Dermatol, London, England.;Int Fdn Dermatol, London, England..
    Hay, Simon I.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Hayat, Khezar
    Univ Vet & Anim Sci, Inst Pharmaceut Sci, Lahore, Pakistan.;Xi An Jiao Tong Univ, Dept Pharm Adm & Clin Pharm, Xian, Peoples R China..
    Heibati, Behzad
    Univ Oulu, Ctr Environm & Resp Hlth Res, Oulu, Finland..
    Heidari, Behnam
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran..
    Heidari, Golnaz
    Heidari-Soureshjani, Reza
    Univ Tehran Med Sci, Sch Nursing & Midwifery, Tehran, Iran..
    Hendrie, Delia
    Curtin Univ, Sch Publ Hlth, Perth, WA, Australia..
    Henny, Kiana
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Henok, Andualem
    Mizan Tepi Univ, Dept Publ Hlth, Mizan Teferi, Ethiopia..
    Henrikson, Hannah J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Henry, Nathaniel J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Herbert, Molly E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Herteliu, Claudiu
    Bucharest Univ Econ Studies, Dept Stat & Econometr, Bucharest, Romania.;London South Bank Univ, Sch Business, London, England..
    Heydarpour, Fatemeh
    Kermanshah Univ Med Sci, Med Biol Res Ctr, Kermanshah, Iran..
    Hird, Thomas R.
    Univ Bath, Dept Hlth, Bath, Avon, England..
    Ho, Hung Chak
    Univ Hong Kong, Dept Urban Planning & Design, Hong Kong, Peoples R China..
    Hoek, Hans W.
    Univ Groningen, Dept Psychiat, Groningen, Netherlands.;Columbia Univ, Dept Epidemiol, New York, NY USA..
    Hole, Michael K.
    Univ Texas Austin, Dept Pediat, Austin, TX 78712 USA..
    Holla, Ramesh
    Manipal Acad Higher Educ, Kasturba Med Coll, Mangalore, India..
    Hollingsworth, Bruce
    Univ Lancaster, Dept Hlth Econ, Lancaster, Lancs, England..
    Hoogar, Praveen
    Manipal Acad Higher Educ, Ctr Bio Cultural Studies CBiCS, Mangalore, India..
    Hopf, Kathleen Pillsbury
    Operat Smile, Metr & Evaluat, Virginia Beach, VA USA..
    Horita, Nobuyuki
    NHGRI, NIH, Bethesda, MD 20892 USA.;Yokohama City Univ, Dept Pulmonol, Yokohama, Kanagawa, Japan..
    Hosgood, H. Dean
    Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA..
    Hossain, Naznin
    Bangladesh Ind Gases Ltd, Dept Pharmacol, Tangail, Bangladesh..
    Hosseini, Mostafa
    Univ Tehran Med Sci, Dept Epidemiol & Biostat, Tehran, Iran.;Univ Tehran Med Sci, Pediat Chron Kidney Dis Res Ctr, Tehran, Iran..
    Hosseinzadeh, Mehdi
    Univ Human Dev, Dept Comp Sci, Sulaymaniyah, Iraq..
    Hostiuc, Mihaela
    Carol Davila Univ Med & Pharm, Dept Internal Med, Bucharest, Romania..
    Hostiuc, Sorin
    Carol Davila Univ Med & Pharm, Dept Legal Med & Bioeth, Bucharest, Romania.;Natl Inst Legal Med Mina Minovici, Clin Legal Med Dept, Bucharest, Romania..
    Househ, Mowafa
    Hamad Bin Khalifa Univ, Div Informat & Comp Technol, Doha, Qatar..
    Hoy, Damian G.
    Univ Sydney, Sydney, NSW, Australia..
    Hsairi, Mohamed
    Univ Tunis El Manar, Fac Med Tunis, Tunis, Tunisia..
    Hsiao, Thomas
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Hsieh, Vivian Chia-Rong
    China Med Univ, Dept Hlth Serv Adm, Taichung, Taiwan..
    Hu, Guoqing
    Cent South Univ, Dept Epidemiol & Hlth Stat, Changsha, Peoples R China..
    Hu, Kejia
    Zhejiang Univ, Sch Publ Hlth, Hangzhou, Peoples R China..
    Huda, Tanvir M.
    Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW, Australia..
    Hugo, Fernando N.
    Univ Fed Rio Grande do Sul, Dept Prevent & Social Dent, Porto Alegre, RS, Brazil..
    Humayun, Ayesha
    Shaikh Khalifa Bin Zayed Al Nahyan Med Coll, Dept Publ Hlth & Community Med, Lahore, Pakistan..
    Hussain, Rabia
    Univ Sci Malaysia, Sch Pharmaceut Sci, George Town, Malaysia..
    Huynh, Chantal K.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Hwang, Bing-Fang
    Kings Coll London, Sch Populat Hlth & Environm Sci, London, England.;China Med Univ, Dept Occupat Safety & Hlth, Taichung, Taiwan..
    Iannucci, Vincent C.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Iavicoli, Ivo
    Univ Naples Federico II, Dept Publ Hlth, Naples, Italy..
    Ibeneme, Charles Ugochukwu
    African Field Epidemiol Network, Nigerian Field Epidemiol & Lab Training Program, Abuja, Nigeria.;Minist Hlth, Dept Publ Hlth & Dis Control, Umuahia, Nigeria.;Duke Kunshan Univ, Global Hlth Res Ctr, Kunshan, Peoples R China..
    Ibitoye, Segun Emmanuel
    Univ Ibadan, Dept Hlth Promot & Educ, Ibadan, Nigeria..
    Ikeda, Nayu
    Natl Inst Biomed Innovat Hlth & Nutr, Int Ctr Nutr & Informat, Tokyo, Japan..
    Ikuta, Kevin S.
    Univ Washington, Div Allergy & Infect Dis, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Ilesanmi, Olayinka Stephen
    Univ Coll Hosp, Dept Community Med, Ibadan, Nigeria.;Univ Ibadan, Dept Community Med, Ibadan, Nigeria..
    Ilic, Irena M.
    Univ Belgrade, Fac Med, Belgrade, Serbia..
    Ilic, Milena D.
    Univ Kragujevac, Dept Epidemiol, Kragujevac, Serbia..
    Imani-Nasab, Mohammad Hasan
    Lorestan Univ Med Sci, Dept Publ Hlth, Khorramabad, Iran..
    Inbaraj, Leeberk Raja
    Bangalore Baptist Hosp, Div Community Hlth & Family Med, Bangalore, Karnataka, India..
    Ippolito, Helen
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Iqbal, Usman
    Taipei Med Univ, Coll Publ Hlth, Taipei, Taiwan..
    Irvani, Seyed Sina Naghibi
    Shahid Beheshti Univ Med Sci, Res Inst Endocrine Sci, Tehran, Iran..
    Irvine, Caleb Mackay Salpeter
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Islam, M. Mofizul
    Taipei Med Univ, Grad Inst Biomed Informat, Taipei, Taiwan..
    Islam, MdMohaimenul
    La Trobe Univ, Dept Publ Hlth, Melbourne, Vic, Australia..
    Islam, Sheikh Mohammed Shariful
    Deakin Univ, Inst Phys Act & Nutr, Burwood, Vic, Australia.;Univ Sydney, Sydney Med Sch, Sydney, NSW, Australia..
    Islami, Farhad
    Amer Canc Soc, Surveillance & Hlth Serv Res, Atlanta, GA 30329 USA..
    Iso, Hiroyasu
    Osaka Univ, Dept Social Med, Suita, Osaka, Japan..
    Ivers, Rebecca Q.
    Univ New South Wales, Sch Publ Hlth & Community Med, Sydney, NSW, Australia..
    Iwu, Chidozie C. D.
    Univ Ft Hare, Dept Biochem & Microbiol, Alice, South Africa..
    Iwu, Chinwe Juliana
    Stellenbosch Univ, Dept Global Hlth, Cape Town, South Africa.;South African Med Res Council, Cape Town, South Africa..
    Iyamu, Ihoghosa Osamuyi
    Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada.;Ctr Hlth Evaluat & Outcome Sci, Knowledge Translat, Vancouver, BC, Canada..
    Jaafari, Jalil
    Guilan Univ Med Sci, Dept Environm Hlth Engn, Rasht, Iran..
    Jacobsen, Kathryn H.
    George Mason Univ, Dept Global & Community Hlth, Fairfax, VA 22030 USA..
    Jadidi-Niaragh, Farhad
    Tabriz Univ Med Sci, Dept Immunol, Tabriz, Iran..
    Jafari, Hussain
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Jafarinia, Morteza
    Isfahan Univ Med Sci, Dept Immunol, Esfahan, Iran..
    Jahagirdar, Deepa
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Jahani, Mohammad Ali
    Babol Univ Med Sci, Social Determinants Hlth Res Ctr, Babol, Iran..
    Jahanmehr, Nader
    Shahid Beheshti Univ Med Sci, Safety Promot & Injury Prevent Res Ctr, Tehran, Iran.;Shahid Beheshti Univ Med Sci, Sch Management & Med Educ, Tehran, Iran..
    Jakovljevic, Mihajlo
    IM Sechenov First Moscow State Med Univ, NA Semashko Dept Publ Hlth & Healthcare, Moscow, Russia.;Univ Kragujevac, Dept Global Hlth Econ & Policy, Kragujevac, Serbia..
    Jalali, Amir
    Kermanshah Univ Med Sci, Hlth Inst, Kermanshah, Iran.;Kermanshah Univ Med Sci, Subst Abuse Prevent Res Ctr, Kermanshah, Iran..
    Jalilian, Farzad
    Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran..
    James, Spencer L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Janjani, Hosna
    Univ Tehran Med Sci, Dept Environm Hlth Engn, Tehran, Iran.;Kermanshah Univ Med Sci, Kermanshah, Iran..
    Janodia, Manthan Dilipkumar
    Javaheri, Tahereh
    Boston Univ, Hlth Informat Lab, Boston, MA 02215 USA..
    Javidnia, Javad
    Mazandaran Univ Med Sci, Dept Med Mycol, Sari, Iran..
    Jayatilleke, Achala Upendra
    Univ Colombo, Postgrad Inst Med, Colombo, Sri Lanka.;Inst Violence & Injury Prevent, Fac Grad Studies, Colombo, Sri Lanka..
    Jeemon, Panniyammakal
    Sree Chitra Tirunal Inst Med Sci & Technol, Achutha Menon Ctr Hlth Sci Studies, Trivandrum, Kerala, India..
    Jenabi, Ensiyeh
    Hamadan Univ Med Sci, Autism Spectrum Disorders Res Ctr, Hamadan, Iran..
    Jha, Ravi Prakash
    Baba Saheb Ambedkar Med Coll & Hosp, Dept Community Med, Delhi, India.;Banaras Hindu Univ, Dept Community Med, Varanasi, Uttar Pradesh, India..
    Jha, Vivekanand
    Univ New South Wales, George Inst Global Hlth, Sydney, NSW, Australia.;Manipal Acad Higher Educ, Mangalore, India..
    Ji, John S.
    Duke Univ, Nicholas Sch Environm, Durham, NC USA.;Duke Kunshan Univ, Environm Res Ctr, Kunshan, Peoples R China..
    Jia, Peng
    Univ Twente, Dept Earth Observat Sci, Enschede, Netherlands..
    Johansson, Lars
    John, Oommen
    Univ New South Wales, Dept Med, Sydney, NSW, Australia.;Univ New South Wales, Renal & Cardiovasc Div, Sydney, NSW, Australia..
    John-Akinola, Yetunde O.
    Univ Ibadan, Dept Hlth Promot & Educ, Ibadan, Nigeria..
    Johnson, Catherine Owens
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Johnson, Sarah Charlotte
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Jonas, Jost B.
    Heidelberg Univ, Dept Ophthalmol, Heidelberg, Germany.;Beijing Tongren Hosp, Beijing Inst Ophthalmol, Beijing, Peoples R China..
    Joo, Tamas
    Semmelweis Univ, Hlth Serv Management Training Ctr, Budapest, Hungary..
    Joshi, Ankur
    All India Inst Med Sci, Dept Community Med & Family Med, Bhopal, India..
    Joukar, Farahnaz
    Guilan Univ Med Sci, Caspian Digest Dis Res Ctr, Rasht, Iran.;Guilan Univ Med Sci, Gastrointestinal & Liver Dis Res Ctr, Rasht, Iran..
    Jozwiak, Jacek Jerzy
    Univ Opole, Dept Family Med & Publ Hlth, Opole, Poland..
    Jurisson, Mikk
    Univ Tartu, Inst Family Med & Publ Hlth, Tartu, Estonia..
    Kabir, Ali
    Iran Univ Med Sci, Minimally Invas Surg Res Ctr, Tehran, Iran..
    Kabir, Zubair
    Univ Coll Cork, Sch Publ Hlth, Cork, Ireland..
    Kalani, Hamed
    Univ Washington, Dept Neurol, Seattle, WA 98195 USA.;Golestan Univ Med Sci, Infect Dis Res Ctr, Gorgan, Golestan, Iran..
    Kalani, Rizwan
    Kalankesh, Leila R.
    Tabriz Univ Med Sci, Hlth Serv Management Res Ctr, Tabriz, Iran..
    Kalhor, Rohollah
    Qazvin Univ Med Sci, Hlth Serv Management Dept, Qazvin, Iran.;Qazvin Univ Med Sci, Inst Prevent Noncommunicable Dis, Qazvin, Iran..
    Kamath, Aruna M.
    Univ Washington, Dept Anesthesiol & Pain Med, Seattle, WA 98195 USA..
    Kamiab, Zahra
    Rafsanjan Univ Med Sci, Clin Res Dev Unit, Rafsanjan, Iran.;Rafsanjan Univ Med Sci, Dept Family Med, Rafsanjan, Iran..
    Kanchan, Tanuj
    All India Inst Med Sci, Dept Forens Med & Toxicol, Jodhpur, Rajasthan, India..
    Kapoor, Neeti
    Govt Inst Forens Sci, Dept Forens Sci, Nagpur, Maharashtra, India..
    Matin, Behzad Karami
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Karanikolos, Marina
    London Sch Hyg & Trop Med, Dept Hlth Serv Res & Policy, London, England.;London Sch Hyg & Trop Med, European Observ Hlth Syst & Policies, London, England..
    Karch, Andre
    Univ Munster, Inst Epidemiol & Social Med, Munster, Germany..
    Karim, Mohd Anisul
    Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England.;Ctr Therapeut Target Validat, Cambridge, England..
    Karimi, Salah Eddin
    Karimi, Seyed Asaad
    Karimi, Seyed M.
    Tabriz Univ Med Sci, Social Determinants Hlth Res Ctr, Tabriz, Iran.;Hamedan Univ Med Sci, Dept Neurosci, Hamadan, Iran.;Hamedan Univ Med Sci, Dept Physiol, Hamadan, Iran.;Univ Louisville, Dept Hlth Management & Syst Sci, Louisville, KY 40292 USA.;Louisville Metro Dept Publ Hlth & Wellness, Ctr Hlth Equ, Louisville, KY USA..
    Kasa, Ayele Semachew
    Bahir Dar Univ, Dept Adult Hlth Nursing, Bahir Dar, Ethiopia..
    Kassa, Getachew Mullu
    Debre Markos Univ, Coll Hlth Sci, Debre Markos, Ethiopia..
    Kassebaum, Nicholas J.
    Univ Washington, Dept Anesthesiol & Pain Med, Seattle, WA 98195 USA.;Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Katikireddi, Srinivasa Vittal
    Univ Glasgow, MRC CSO Social & Publ Hlth Sci Unit, Glasgow, Lanark, Scotland..
    Kawakami, Norito
    Univ Tokyo, Dept Mental Hlth, Tokyo, Japan..
    Kayode, Gbenga A.
    Inst Human Virol Nigeria, Int Res Ctr Excellence, Abuja, Nigeria.;Univ Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands..
    Karyani, Ali Kazemi
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Keddie, Suzanne H.
    Univ Oxford, Big Data Inst, Oxford, England..
    Keiyoro, Peter Njenga
    Univ Nairobi, Open Distance & eLearning Campus, Nairobi, Kenya..
    Keller, Cathleen
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Kemmer, Laura
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Kendrick, Parkes J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Kereselidze, Maia
    Natl Ctr Dis Control & Publ Hlth, Tbilisi, Georgia..
    Khader, Yousef Saleh
    Jordan Univ Sci & Technol, Dept Publ Hlth, Irbid, Jordan..
    Khafaie, Morteza Abdullatif
    Ahvaz Jundishapur Univ Med Sci, Social Determinants Hlth Res Ctr, Ahwaz, Iran..
    Khalid, Nauman
    Univ Management & Technol, Sch Food & Agr Sci, Lahore, Pakistan..
    Khammarnia, Mohammad
    Zahedan Univ Med Sci, Hlth Promot Res Ctr, Zahedan, Iran..
    Khan, Ejaz Ahmad
    Hlth Serv Acad, Dept Epidemiol & Biostat, Islamabad, Pakistan..
    Khan, Gulfaraz
    United Arab Emirates Univ, Dept Med Microbiol & Immunol, Al Ain, U Arab Emirates..
    Khan, Maseer
    Jazan Univ, Dept Epidemiol, Jazan, Saudi Arabia..
    Khang, Young-Ho
    Seoul Natl Univ, Dept Hlth Policy & Management, Seoul, South Korea.;Seoul Natl Univ, Inst Hlth Policy & Management, Seoul, South Korea..
    Khatab, Khaled
    Sheffield Hallam Univ, Fac Hlth & Wellbeing, Sheffield, S Yorkshire, England.;Ohio Univ, Coll Arts & Sci, Zanesville, OH USA..
    Khater, Amir M.
    Cairo Univ, Natl Hepatol & Trop Med Res Inst, Cairo, Egypt..
    Khater, Mona M.
    Cairo Univ, Dept Med Parasitol, Cairo, Egypt..
    Khatib, Mahalaqua Nazli
    Datta Meghe Inst Med Sci, Global Evidence Synth Initiat, Wardha, India..
    Khayamzadeh, Maryam
    Shahid Beheshti Univ Med Sci, Tehran, Iran.;Iranian Acad Med Sci, Tehran, Iran..
    Khazaei, Salman
    Hamadan Univ Med Sci, Dept Epidemiol, Hamadan, Iran..
    Khazaie, Habibolah
    Kermanshah Univ Med Sci, Dept Psychiat, Kermanshah, Iran..
    Khodayari, Mohammad Taghi
    Tabriz Univ Med Sci, Dept Publ Hlth, Tabriz, Iran.;Maragheh Univ Med Sci, Dept Publ Hlth, Maragheh, Iran..
    Khoja, Abdullah T.
    Johns Hopkins Univ, Dept Hlth Policy & Management, Baltimore, MD 21218 USA.;Imam Mohammad Ibn Saud Islamic Univ, Dept Publ Hlth, Riyadh, Saudi Arabia..
    Khubchandani, Jagdish
    Ball State Univ, Dept Nutr & Hlth Sci, Muncie, IN 47306 USA..
    Khundkar, Roba
    Univ Oxford, Nuffield Dept Surg Sci, Oxford, England..
    Kianipour, Neda
    Kermanshah Univ Med Sci, Dept Publ Hlth, Kermanshah, Iran..
    Kieling, Christian
    Univ Fed Rio Grande do Sul, Dept Psychiat, Porto Alegre, RS, Brazil.;Clin Hosp, Div Child & Adolescent Psychiat, Porto Alegre, RS, Brazil..
    Kim, Cho-Il
    Korea Hlth Ind Dev Inst, Cheongju, South Korea..
    Kim, Daniel
    Northeastern Univ, Dept Hlth Sci, Boston, MA 02115 USA..
    Kim, Young-Eun
    Korea Univ, Dept Prevent Med, Seoul, South Korea..
    Kim, Yun Jin
    Xiamen Univ Malaysia, Sch Tradit Chinese Med, Sepang, Malaysia..
    Kimokoti, Ruth W.
    Simmons Univ, Dept Nutr, Boston, MA USA..
    Kinfu, Yohannes
    Univ Canberra, Fac Hlth, Canberra, ACT, Australia.;Qatar Univ, Coll Med, Doha, Qatar..
    Kisa, Adnan
    Kristiania Univ Coll, Sch Hlth Sci, Oslo, Norway.;Tulane Univ, Global Community Hlth & Behav Sci, New Orleans, LA 70118 USA..
    Kisa, Sezer
    Oslo Metropolitan Univ, Dept Nursing & Hlth Promot, Oslo, Norway..
    Kissimova-Skarbek, Katarzyna
    Jagiellonian Univ, Coll Med, Dept Hlth Econ & Social Secur, Krakow, Poland..
    Kissoon, Niranjan
    Univ British Columbia, Dept Pediat, Vancouver, BC, Canada..
    Kivimaki, Mika
    UCL, Dept Epidemiol & Publ Hlth, London, England.;Univ Helsinki, Dept Publ Hlth, Helsinki, Finland..
    Kneib, Cameron J.
    Univ Washington, Div Plast Surg, Seattle, WA 98195 USA..
    Knibbs, Luke D.
    Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia..
    Knight, Megan
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Knudsen, Ann Kristin Skrindo
    Norwegian Inst Publ Hlth, Ctr Dis Burden, Bergen, Norway..
    Kocarnik, Jonathan M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1124 Columbia St, Seattle, WA 98104 USA..
    Kochhar, Sonali
    Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA.;Global Healthcare Consulting, New Delhi, India..
    Koh, David S. Q.
    Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Inst Hlth Sci, Gadong, Brunei..
    Kohler, Stefan
    Heidelberg Univ, Heidelberg Inst Global Hlth HIGH, Heidelberg, Germany..
    Kolola, Tufa
    Ambo Univ, Dept Publ Hlth, Ambo, Ethiopia..
    Komaki, Hamidreza
    Hamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran.;Inst Res Fundamental Sci, Brain Engn Res Ctr, Tehran, Iran..
    Kopec, Jacek A.
    Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada.;Arthrit Res Canada, Richmond, BC, Canada..
    Korotkova, Anna V.
    Minist Hlth FRIHOI, Fed Res Inst Hlth Org & Informat, Moscow, Russia..
    Korshunov, Vladimir Andreevich
    IM Sechenov First Moscow State Med Univ, Dept Epidemiol & Evidence Based Med, Moscow, Russia..
    Kosen, Soewarta
    Kotlo, Anirudh
    Vancouver Virol Ctr, Dept Global Hlth, Vancouver, BC, Canada..
    Koul, Parvaiz A.
    Sheri Kashmir Inst Med Sci, Dept Internal & Pulm Med, Srinagar, India..
    Koyanagi, Ai
    Catalan Inst Res & Adv Studies ICREA, Barcelona, Spain.;Biomed Res Networking Ctr Mental Hlth Network CIB, San Juan Dios Sanitary Pk, St Boi De Llobregat, Spain..
    Kraemer, Moritz U. G.
    Harvard Univ, Harvard Med Sch, Boston, MA 02115 USA.;Univ Oxford, Dept Zool, Oxford, England..
    Kravchenko, Michael A.
    Res Ctr Neurol, Moscow, Russia..
    Krishan, Kewal
    Panjab Univ, Dept Anthropol, Chandigarh, India. Govt Med Coll Thrissur, Dept Psychiat, Trichur, India. Kerala Univ Hlth Scinces, Trichur, India..
    Krohn, Kris J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Kromhout, Hans
    Univ Utrecht, Inst Risk Assessment Sci IRAS, Utrecht, Netherlands..
    Shaji, K. S.
    Defo, Barthelemy Kuate
    Univ Montreal, Dept Demog, Montreal, PQ, Canada.;Univ Montreal, Dept Social & Prevent Med, Montreal, PQ, Canada..
    Bicer, Burcu Kucuk
    Gazi Univ, Dept Med Educ & Informat, Ankara, Turkey..
    Kugbey, Nuworza
    Univ Hlth & Allied Sci, Dept Family & Community Hlth, Ho, Ghana..
    Kulkarni, Vaman
    Manipal Acad Higher Educ, Dept Community Med, Mangalore, India..
    Kumar, G. Anil
    Kumar, Manasi
    UCL, Div Psychol & Language Sci, London, England.;Univ Nairobi, Dept Psychiat, Nairobi, Kenya..
    Kumar, Nithin
    Manipal Acad Higher Educ, Dept Community Med, Mangalore, India..
    Kumar, Pushpendra
    Kumar, Vivek
    Harvard Univ, Brigham & Womens Hosp, Boston, MA 02115 USA..
    Kumaresh, Girikumar
    Indian Inst Technol, Mech & Ind Engn, Roorkee, Uttar Pradesh, India..
    Kurmi, Om P.
    McMaster Univ, Dept Med, Hamilton, ON, Canada.;Univ Birmingham, Inst Occupat & Environm Med, Birmingham, W Midlands, England..
    Kusuma, Dian
    Imperial Coll London, Imperial Coll Business Sch, London, England.;Univ Indonesia, Fac Publ Hlth, Depok, Indonesia..
    Kyu, Hmwe Hmwe
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    La Vecchia, Carlo
    Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy..
    Lacey, Ben
    Lal, Dharmesh Kumar
    Publ Hlth Fdn India, Gurugram, India..
    Lalloo, Ratilal
    Univ Queensland, Sch Dent, Brisbane, Qld, Australia..
    Lallukka, Tea
    Univ Helsinki, Dept Publ Hlth, Helsinki, Finland..
    Lam, Jennifer O.
    Kaiser Permanente, Div Res, Fontana, CA USA..
    Lami, Faris Hasan
    Univ Baghdad, Dept Community & Family Med, Baghdad, Iraq..
    Lan, Qing
    NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA..
    Landires, Ivan
    Inst Med Sci, Unit Genet & Publ Hlth, Las Tablas, Panama.;Minist Hlth, Herrera, Panama..
    Lang, Justin J.
    Publ Hlth Agcy Canada, Ctr Surveillance & Appl Res, Toronto, ON, Canada..
    Langan, Sinead M.
    London Sch Hyg & Trop Med, Fac Epidemiol & Populat Hlth, London, England.;Guys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, London, England..
    Lansingh, Van Charles
    HelpMeSee, New York, NY USA.;Mexican Inst Ophthalmol, Queretaro, Mexico..
    Lansky, Sonia
    Municipal Hlth Dept Belo Horizonte, Belo Horizonte City Hall, Belo Horizonte, MG, Brazil..
    Larson, Heidi Jane
    London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, London, England.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Larson, Samantha Leigh
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Larsson, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Chemistry. Uppsala Univ Hosp, Dept Clin Chem & Pharmacol, Uppsala, Sweden..
    Lasrado, Savita
    Father Muller Med Coll, Dept Otorhinolaryngol, Mangalore, India..
    Lassi, Zohra S.
    Univ Adelaide, Robinson Res Inst, Adelaide, SA, Australia..
    Lau, Kathryn Mei-Ming
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Lauriola, Paolo
    CNR, Inst Clin Physiol, Padua, Italy..
    Lavados, Pablo M.
    German Clin Santiago, Dept Neurol & Psychiat, Santiago, Chile.;Univ Dev, Fac Med, Santiago, Chile..
    Lazarus, Jeffrey V.
    Leal, Lisiane F.
    McGill Univ, Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada.;Jewish Gen Hosp, Ctr Clin Epidemiol, Montreal, PQ, Canada..
    Leasher, Janet L.
    Nova Southeastern Univ, Coll Optometry, Ft Lauderdale, FL 33314 USA..
    Ledesma, Jorge R.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Lee, Paul H.
    Hong Kong Polytech Univ, Sch Nursing, Hong Kong, Peoples R China..
    Lee, Shaun Wen Huey
    Monash Univ, Sch Pharm, Melbourne, Vic, Australia.;Taylors Univ Lakeside Campus, Sch Pharm, Subang Jaya, Malaysia..
    Leever, Andrew T.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    LeGrand, Kate E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Leigh, James
    Univ Sydney, Asbestos Dis Res Inst, Sydney, NSW, Australia..
    Leonardi, Matilde
    Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy..
    Lescinsky, Haley
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Leung, Janni
    Univ Queensland, Ctr Youth Subst Abuse Res, Brisbane, Qld, Australia..
    Levi, Miriam
    USL Tuscany Ctr, Dept Prevent, Florence, Italy..
    Lewington, Sarah
    Univ Oxford, Med Res Council Populat Hlth Res Unit, Oxford, England.;Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England..
    Li, Bingyu
    Shenzhen Univ, Dept Sociol, Shenzhen, Peoples R China..
    Li, Shanshan
    Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia..
    Lim, Lee-Ling
    Univ Malaya, Dept Med, Kuala Lumpur, Malaysia.;Chinese Univ Hong Kong, Dept Med & Therapeut, Shatin, Peoples R China..
    Lin, Christine
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Lin, Ro-Ting
    China Med Univ, Coll Publ Hlth, Taichung, Taiwan.;Asbestos Dis Res Inst, Concord, NSW, Australia..
    Linehan, Christine
    Univ Coll Dublin, UCD Ctr Disabil Studies, Dublin, Ireland..
    Linn, Shai
    Univ Haifa, Sch Publ Hlth, Haifa, Israel..
    Listl, Stefan
    Radboud Univ Nijmegen, Dept Dentistry Qual & Safety Oral Hlth Care, Nijmegen, Netherlands.;Heidelberg Univ Hosp, Dept Translat Hlth Econ, Heidelberg, Germany..
    Liu, Hung-Chun
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Liu, Shiwei
    Brown Univ, Dept Epidemiol, Providence, RI 02912 USA..
    Liu, Simin
    Liu, Xuefeng
    Univ Michigan, Dept Syst Populat & Leadership, Ann Arbor, MI 48109 USA..
    Liu, Yang
    Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA..
    Liu, Zichen
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Lo, Justin
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Lodha, Rakesh
    All India Inst Med Sci, Dept Paediat, New Delhi, India..
    Logroscino, Giancarlo
    Univ Bari Aldo Moro, Dept Basic Med Sci Neurosci & Sense Organs, Bari, Italy.;Fdn Cardinale Giovanni Panico Hosp, Dept Clin Res Neurol, Tricase, Italy..
    Looker, Katharine J.
    Univ Bristol, Populat Hlth Sci, Bristol, Avon, England..
    Lopez, Alan D.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia..
    Lopez, Jaifred Christian F.
    Univ Philippines Manila, Dept Nutr, Manila, Philippines.;Alliance Improving Hlth Outcomes Inc, Quezon City, Philippines..
    Lopukhov, Platon D.
    IM Sechenov First Moscow State Med Univ, Dept Epidemiol & Evidence Based Med, Moscow, Russia..
    Lorkowski, Stefan
    Friedrich Schiller Univ Jena, Inst Nutr Sci, Jena, Germany.;Competence Cluster Nutr & Cardiovasc Hlth nutriCA, Jena, Germany..
    Lotufo, Paulo A.
    Univ Sao Paulo, Dept Med, Sao Paulo, Brazil..
    Lozano, Rafael
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Lu, Alton
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Lucas, Tim C. D.
    Univ Oxford, Big Data Inst, Oxford, England..
    Lugo, Alessandra
    Mario Negri Inst Pharmacol Res, Dept Environm Hlth Sci, Milan, Italy..
    Lunevicius, Raimundas
    Liverpool Univ Hosp NHS Fdn Trust, Dept Gen Surg, Liverpool, Merseyside, England.;Univ Liverpool, Dept Surg, Liverpool, Merseyside, England..
    Lyons, Ronan A.
    Swansea Univ, Sch Med, Swansea, W Glam, Wales..
    Ma, Jianing
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Machado, Daiane Borges
    London Sch Hyg & Trop Med, Ctr Global Mental Hlth CGMH, London, England.;Oswald Cruz Fdn FIOCRUZ, Ctr Integrat Data & Hlth Knowledge, Salvador, BA, Brazil..
    MacLachlan, Jennifer H.
    Peter Doherty Inst Infect & Immun, Epidemiol, Melbourne, Vic, Australia..
    Madadin, Mohammed
    Imam Abdulrahman Bin Faisal Univ, Dept Pathol, Dammam, Saudi Arabia..
    Maddison, Emilie R.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Maddison, Ralph
    Deakin Univ, Inst Phys Act & Nutr, Burwood, Vic, Australia..
    Madotto, Fabiana
    IRCCS MultiMed, Value Based Healthcare, Sesto San Giovanni, Italy..
    Abd El Razek, Hassan Magdy
    Mansoura Fac Med, Dept Radiol, Mansoura, Egypt..
    Abd El Razek, Muhammed Magdy
    Minist Hlth Populat, Dept Ophthalmol, Aswan, Egypt..
    Mahasha, Phetole Walter
    South African Med Res Council, Grants Innovat & Product Dev Unit, Cape Town, South Africa..
    Mahdavi, Mokhtar Mahdavi
    Saveh Univ Med Sci, Social Determinants Hlth Res Ctr, Saveh, Iran.;Michigan State Univ, Acad Med Sci, E Lansing, MI 48824 USA..
    Mahmoudi, Morteza
    Michigan State Univ, Radiol & Precis Hlth Program, E Lansing, MI 48824 USA..
    Mai, Hue Thi
    Duy Tan Univ, Inst Global Hlth Innovat, Da Nang, Vietnam..
    Majeed, Azeem
    Imperial Coll London, Dept Primary Care & Publ Hlth, London, England..
    Malagon-Rojas, Jeadran N.
    Natl Inst Hlth, Dept Publ Hlth Res, Bogota, Colombia.;El Bosque Univ, Fac Med, Bogota, Colombia..
    Maled, Venkatesh
    Rajiv Gandhi Univ Hlth Sci, Dept Forens Med, Dharwad, Karnataka, India.;Shri Dharmasthala Manjunatheshwara Univ, Dept Forens Med, Dharwad, Karnataka, India..
    Maleki, Afshin
    Kurdistan Univ Med Sci, Environm Hlth Res Ctr, Sanandaj, Iran..
    Maleki, Shokofeh
    Kermanshah Univ Med Sci, Clin Res Dev Ctr, Kermanshah, Iran..
    Malekzadeh, Reza
    Univ Tehran Med Sci, Digest Dis Res Ctr, Tehran, Iran.;Shiraz Univ Med Sci, Noncommunicable Dis Res Ctr, Shiraz, Iran..
    Malta, Deborah Carvalho
    Univ Fed Minas Gerais, Dept Maternal & Child Nursing & Publ Hlth, Belo Horizonte, MG, Brazil..
    Mamun, Abdullah A.
    Univ Queensland, Social Sci Res Inst, Brisbane, Qld, Australia..
    Manafi, Amir
    Univ Virginia, Dept Surg, Charlottesville, VA USA..
    Manafi, Navid
    Iran Univ Med Sci, Dept Ophthalmol, Tehran, Iran.;Univ Manitoba, Dept Ophthalmol, Winnipeg, MB, Canada..
    Manda, Ana Laura
    Carol Davila Univ Med & Pharm, Dept Gen Surg, Bucharest, Romania.;Emergency Univ Hosp Bucharest, Dept Gen Surg 1, Bucharest, Romania..
    Manguerra, Helena
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Mansour-Ghanaei, Fariborz
    Guilan Univ Med Sci, Caspian Digest Dis Res Ctr, Rasht, Iran.;Guilan Univ Med Sci, Gastrointestinal & Liver Dis Res Ctr, Rasht, Iran..
    Mansouri, Borhan
    Kermanshah Univ Med Sci, Subst Abuse Prevent Res Ctr, Kermanshah, Iran..
    Mansournia, Mohammad Ali
    Univ Tehran Med Sci, Dept Epidemiol & Biostat, Tehran, Iran..
    Herrera, Ana M. Mantilla
    Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia.;Queensland Ctr Mental Hlth Res, Psychiat Epidemiol & Burden Dis Res, Brisbane, Qld, Australia..
    Mapoma, Chabila Christopher
    Univ Zambia, Dept Populat Studies, Lusaka, Zambia..
    Maravilla, Joemer C.
    Univ Queensland, Social Sci Res Inst, Brisbane, Qld, Australia..
    Marks, Ashley
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Martin, Randall V.
    Dalhousie Univ, Dept Phys & Atmospher Sci, Halifax, NS, Canada.;Washington Univ, Dept Energy Environm & Chem Engn, St Louis, MO USA..
    Martini, Santi
    Airlangga Univ, Fac Publ Hlth, Surabaya, Indonesia.;Indonesian Publ Hlth Assoc, Surabaya, Indonesia..
    Martins-Melo, Francisco Rogerlandio
    Fed Inst Educ Sci & Technol, Campus Caucaia, Caucaia, Brazil..
    Martopullo, Ira
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Masaka, Anthony
    Botho Univ Botswana, Fac Hlth & Educ, Gaborone, Botswana..
    Masoumi, Seyedeh Zahra
    Hamadan Univ Med Sci, Dept Midwifery, Hamadan, Iran..
    Massano, Joao
    Univ Porto, Dept Clin Neurosci & Mental Hlth, Porto, Portugal.;Univ Hosp Ctr Sao Joao, Dept Neurol, Porto, Portugal..
    Massenburg, Benjamin Ballard
    Univ Washington, Div Plast & Reconstruct Surg, Seattle, WA 98195 USA..
    Mastrogiacomo, Claudia I.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Mathur, Manu Raj
    Publ Hlth Fdn India, Hlth Policy Res, Gurugram, India.;Univ Liverpool, Inst Populat Hlth Sci, Liverpool, Merseyside, England..
    Matsushita, Kunihiro
    Johns Hopkins Univ, Dept Epidemiol, Baltimore, MD USA..
    Maulik, Pallab K.
    Univ New South Wales, Sch Med, Sydney, NSW, Australia.;Univ New South Wales, Div Res, Sydney, NSW, Australia..
    May, Erin A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Mazidi, Mohsen
    Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England..
    McAlinden, Colm
    Singleton Hosp, Dept Ophthalmol, Swansea, W Glam, Wales..
    McGrath, John J.
    Univ Queensland, Queensland Brain Inst, Brisbane, Qld, Australia.;Aarhus Univ, Natl Ctr Register Based Res, Aarhus, Denmark..
    Mckee, Martin
    London Sch Hyg & Trop Med, Dept Hlth Serv Res & Policy, London, England..
    Medina-Solis, Carlo Eduardo
    Autonomous Univ Hidalgo State, Acad Area Dent, Pachuca, Hidalgo, Mexico..
    Meharie, Birhanu Geta
    Wollo Univ, Dept Pharm, Dessie, Ethiopia..
    Mehndiratta, Man Mohan
    Janakpuri Super Specialty Hosp Soc, Dept Neurol, New Delhi, India.;Govind Ballabh Inst Med Educ & Res, Dept Neurol, New Delhi, India..
    Nasab, Entezar Mehrabi
    Univ Tehran Med Sci, Tehran Heart Ctr, Tehran, Iran..
    Mehri, Fereshteh
    Iran Univ Med Sci, Nutr Hlth Res Ctr, Tehran, Iran..
    Mehrotra, Ravi
    Indian Council Med Res, India Canc Res Consortium, New Delhi, India..
    Mehta, Kala M.
    Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA..
    Meitei, Wahengbam Bigyananda
    Int Inst Populat Sci, Dept Publ Hlth & Mortal Studies, Mumbai, Maharashtra, India..
    Mekonnen, Teferi
    Univ Oslo, Dept Nutr, Oslo, Norway..
    Melese, Addisu
    Bahir Dar Univ, Dept Med Lab Sci, Bahir Dar, Ethiopia..
    Memiah, Peter T. N.
    Univ Maryland, Inst Human Virol, Baltimore, MD 21201 USA..
    Memish, Ziad A.
    Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia.;Minist Hlth, Res & Innovat Ctr, Riyadh, Saudi Arabia..
    Mendoza, Walter
    United Nations Populat Fund UNFPA, Peru Country Off, Lima, Peru..
    Menezes, Ritesh G.
    Imam Abdulrahman Bin Faisal Univ, Forens Med Div, Dammam, Saudi Arabia..
    Mengesha, Endalkachew Worku
    Bahir Dar Univ, Dept Reprod Hlth & Populat Studies, Bahir Dar, Ethiopia..
    Mengesha, Meresa Berwo
    Adigrat Univ, Dept Midwifery, Adigrat, Ethiopia..
    Mensah, George A.
    Univ Cape Town, Dept Med, Cape Town, South Africa.;NIH, Ctr Translat Res & Implementat Sci, Bldg 10, Bethesda, MD 20892 USA..
    Mereke, Alibek
    Asfendiyarov Kazakh Natl Med Univ, Dept Cardiovasc Surg, Alma Ata, Kazakhstan..
    Mereta, Seid Tiku
    Jimma Univ, Dept Environm Hlth Sci & Technol, Jimma, Ethiopia..
    Meretoja, Atte
    Univ Melbourne, Sch Hlth Sci, Melbourne, Vic, Australia.;Helsinki Univ Hosp, Neurol Unit, Helsinki, Finland..
    Meretoja, Tuomo J.
    Univ Helsinki, Helsinki, Finland.;Helsinki Univ Hosp, Breast Surg Unit, Helsinki, Finland..
    Mestrovic, Tomislav
    Zora Profoz Polyclin, Clin Microbiol & Parasitol Unit, Zagreb, Croatia.;Univ North, Univ Ctr Varazdin, Varazhdin, Croatia..
    Miazgowski, Bartosz
    Pomeranian Med Univ, Ctr Innovat Med Educ, Szczecin, Poland.;Pomeranian Med Univ, Szczecin, Poland..
    Miazgowski, Tomasz
    Pomeranian Med Univ, Dept Propedeut Internal Dis & Arterial Hypertens, Szczecin, Poland..
    Michalek, Irmina Maria
    Vaud Univ Hosp Ctr, Dept Women Mother Child, Lausanne, Switzerland..
    Mihretie, Kebadnew Mulatu
    Bahir Dar Univ, Dept Epidemiol & Biostat, Bahir Dar, Ethiopia..
    Miller, Ted R.
    Curtin Univ, Sch Publ Hlth, Perth, WA, Australia.;Pacific Inst Res & Evaluat, Calverton, MD USA..
    Mills, Edward J.
    McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada..
    Milne, George J.
    Univ Western Australia, Dept Comp Sci & Software Engn, Perth, WA, Australia..
    Mini, G. K.
    Ananthapuri Hosp & Res Inst, Global Inst Publ Hlth, Trivandrum, Kerala, India.;Womens Inst Social & Hlth Studies, Trivandrum, Kerala, India.;Sabzevar Univ Med Sci, Dept Environm Hlth, Sabzevar, Iran..
    Miri, Mohammad
    Sabzevar Univ Med Sci, Noncommunicable Dis Res Ctr, Sabzevar, Iran..
    Mirica, Andreea
    Bucharest Univ Econ Studies, Dept Stat & Econometr, Bucharest, Romania..
    Mirrakhimov, Erkin M.
    Kyrgyz State Med Acad, Internal Med Programme, Bishkek, Kyrgyzstan.;Natl Ctr Cardiol & Internal Dis, Dept Atherosclerosis & Coronary Heart Dis, Bishkek, Kyrgyzstan..
    Mirzaei, Hamed
    Kashan Univ Med Sci, Res Ctr Biochem & Nutr Metab Dis, Kashan, Iran..
    Mirzaei, Maryam
    Kermanshah Univ Med Sci, Dept Rehabil & Sports Med, Kermanshah, Iran..
    Mirzaei, Roya
    Univ Tehran Med Sci, Water Qual Res Ctr, Tehran, Iran.;Iran Univ Med Sci, Comprehens Res Lab, Tehran, Iran..
    Mirzaei-Alavijeh, Mehdi
    Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran..
    Misganaw, Awoke Temesgen
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Mitchell, Philip B.
    Univ New South Wales, Sch Psychiat, Sydney, NSW, Australia..
    Mithra, Prasanna
    Manipal Acad Higher Educ, Dept Community Med, Mangalore, India..
    Moazen, Babak
    Heidelberg Univ, Heidelberg Inst Global Hlth HIGH, Heidelberg, Germany.;Frankfurt Univ Appl Sci, Inst Addict Res ISFF, Frankfurt, Germany..
    Moghadaszadeh, Masoud
    Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz, Iran.;Tabriz Univ Med Sci, Mol Med Res Ctr, Tabriz, Iran..
    Mohajer, Bahram
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran..
    Mohamad, Osama
    Univ Calif San Francisco, Dept Radiat Oncol, San Francisco, CA USA..
    Mohamadi, Efat
    Univ Tehran Med Sci, Hlth Equ Res Ctr, Tehran, Iran..
    Mohammad, Dara K.
    Karolinska Inst, Dept Med, Stockholm, Sweden.;Salahaddin Univ Erbil, Dept Forestry, Erbil, Iraq..
    Mohammad, Yousef
    King Saud Univ, Dept Internal Med, Riyadh, Saudi Arabia..
    Mezerji, Naser Mohammad Gholi
    Hamadan Univ Med Sci, Dept Biostat, Hamadan, Iran..
    Mohammadbeigi, Abolfazl
    Qom Univ Med Sci, Dept Epidemiol & Biostat, Qom, Iran.;Qom Univ Med Sci, Neurosci Res Ctr, Qom, Iran..
    Mohammadian-Hafshejani, Abdollah
    Shahrekord Univ Med Sci, Dept Epidemiol & Biostat, Shahrekord, Iran..
    Mohammadifard, Noushin
    Isfahan Univ Med Sci, Isfahan Cardiovasc Res Inst, Esfahan, Iran..
    Mohammadpourhodki, Reza
    Mashhad Univ Med Sci, Kashmar Ctr Higher Hlth Educ, Mashhad, Razavi Khorasan, Iran..
    Mohammed, Ammas Siraj
    Haramaya Univ, Sch Pharm, Harar, Ethiopia..
    Mohammed, Hussen
    Dire Dawa Univ, Dept Publ Hlth, Dire Dawa, Ethiopia..
    Mohammed, Jemal Abdu
    Samara Univ, Dept Publ Hlth, Samara, Ethiopia..
    Mohammed, Shafiu
    Heidelberg Univ, Heidelberg Inst Global Hlth HIGH, Heidelberg, Germany.;Ahmadu Bello Univ, Hlth Syst & Policy Res Unit, Zaria, Nigeria..
    Mohebi, Farnam
    Univ Tehran Med Sci, Natl Inst Hlth Res NIHR, Tehran, Iran.;Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran..
    Bandpei, Mohammad A. Mohseni
    Univ Social Welf & Rehabil Sci, Pediat Neurorehabilitat Res Ctr, Tehran, Iran..
    Mokari, Amin
    Shahid Beheshti Univ Med Sci, Dept Community Nutr, Tehran, Iran..
    Mokdad, Ali H.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Molokhia, Mariam
    Kings Coll London, Fac Life Sci & Med, London, England..
    Momen, Natalie C.
    Aarhus Univ, Natl Ctr Register Based Res, Aarhus, Denmark..
    Monasta, Lorenzo
    Burlo Garofolo Inst Maternal & Child Hlth, Clin Epidemiol & Publ Hlth Res Unit, Trieste, Italy..
    Mondello, Stefania
    Messina Univ, Dept Biomed & Dent Sci & Morphofunct Imaging, Messina, Italy..
    Mooney, Meghan D.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Moosazadeh, Mahmood
    Mazandaran Univ Med Sci, Hlth Sci Res Ctr, Sari, Iran..
    Moradi, Ghobad
    Kurdistan Univ Med Sci, Dept Epidemiol & Biostat, Sanandaj, Iran.;Kurdistan Univ Med Sci, Social Determinants Hlth Res Ctr, Sanandaj, Iran..
    Moradi, Masoud
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Moradi-Joo, Mohammad
    Iran Hlth Insurance Org, Natl Ctr Hlth Insurance Res, Tehran, Iran..
    Moradi-Lakeh, Maziar
    Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran..
    Moradzadeh, Rahmatollah
    Arak Univ Med Sci, Dept Epidemiol, Arak, Iran..
    Moraga, Paula
    Univ Bath, Dept Math Sci, Bath, Avon, England..
    Morales, Linda
    Natl Inst Publ Hlth, Ctr Poplulat Hlth Res, Cuernavaca, Morelos, Mexico..
    Morawska, Lidia
    Queensland Univ Technol, Int Lab Air Qual & Hlth, Brisbane, Qld, Australia..
    Velasquez, Ilais Moreno
    Gorgas Mem Inst Hlth Studies, Panama City, Panama..
    Morgado-da-Costa, Joana
    Univ Porto, Hosp Ctr Porto, Porto, Portugal..
    Morrison, Shane Douglas
    Univ Washington, Div Plast & Reconstruct Surg, Seattle, WA 98195 USA..
    Mosapour, Abbas
    Babol Univ Med Sci, Dept Clin Biochem, Babol, Iran.;Tarbiat Modares Univ, Dept Clin Biochem, Tehran, Iran..
    Mosser, Jonathan F.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Mouodi, Simin
    Babol Univ Med Sci, Social Determinants Hlth Res Ctr, Babol, Iran..
    Mousavi, Seyyed Meysam
    Univ Tehran Med Sci, Dept Hlth Policy Management & Econ, Tehran, Iran..
    Khaneghah, Amin Mousavi
    Univ Campinas Unicamp, Dept Food Sci, Campinas, Brazil..
    Mueller, Ulrich Otto
    Ctr Populat & Hlth, Wiesbaden, Germany..
    Mukhopadhyay, Satinath
    Seth Sukhlal Karnani Mem Hosp, Dept Endocrinol & Metab, Kolkata, India..
    Mullany, Erin C.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Mumford, John Everett
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Munro, Sandra B.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Muriithi, Moses K.
    Univ Nairobi, Sch Econ, Nairobi, Kenya..
    Musa, Kamarul Imran
    Sci Univ Malaysia, Sch Med Sci, Kubang Kerian, Malaysia..
    Mustafa, Ghulam
    Childrens Hosp & Inst Child Hlth, Dept Pediat Med, Multan, Pakistan.;Inst Mother & Child Care, Dept Pediat & Pediat Pulmonol, Multan, Pakistan..
    Muthupandian, Saravanan
    Mekelle Univ, Dept Microbiol & Immunol, Mekelle, Ethiopia..
    Nabavizadeh, Behnam
    Univ Tehran Med Sci, Dept Urol, Tehran, Iran..
    Nabhan, Ashraf F.
    Ain Shams Univ, Dept Obstet & Gynecol, Cairo, Egypt.;Egyptian Ctr Evidence Based Med, Knowledge Translat & Utilizat Unit, Mansoura, Egypt..
    Naderi, Mehdi
    Kermanshah Univ Med Sci, Clin Res Dev Ctr, Kermanshah, Iran..
    Nagarajan, Ahamarshan Jayaraman
    Initiat Financing Hlth & Human Dev, Res & Analyt Dept, Chennai, Tamil Nadu, India.;Bioinsilico Technol, Dept Res & Analyt, Chennai, Tamil Nadu, India..
    Nagel, Gabriele
    Ulm Univ, Inst Epidemiol & Med Biometry, Ulm, Germany..
    Naghavi, Mohsen
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Naghshtabrizi, Behshad
    Hamedan Univ Med Sci, Dept Cardiol, Hamadan, Iran..
    Naik, Gurudatta
    Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL 35294 USA..
    Naimzada, Mukhammad David
    Moscow Inst Phys & Technol, Lab Publ Hlth Indicators Anal & Hlth Digitalizat, Dolgoprudnyi, Russia.;Kursk State Med Univ, Expt Surg & Oncol Lab, Kursk, Russia..
    Nair, Sanjeev
    Govt Med Coll Trivandrum, Dept Pulm Med, Trivandrum, Kerala, India.;Hlth Act People, Trivandrum, Kerala, India..
    Najafi, Farid
    Kermanshah Univ Med Sci, Epidemiol & Biostat Dept, Kermanshah, Iran.;Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Naldi, Luigi
    San Bortolo Hosp, Dept Dermatol, Vicenza, Italy.;Italian Grp Epidemiol Res Dermatol GISED Study Ct, Study Ctr, Bergamo, Italy..
    Nandakumar, Vishnu
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Nandi, Anita K.
    Univ Oxford, Nuffield Dept Med, Oxford, England..
    Nangia, Vinay
    Suraj Eye Inst, Nagpur, Maharashtra, India..
    Nansseu, Jobert Richie
    Minist Publ Hlth, Dept Control Dis Epidem & Pandem, Yaounde, Cameroon.;Univ Yaounde I, Dept Publ Hlth, Yaounde, Cameroon..
    Naserbakht, Morteza
    Iran Univ Med Sci, Mental Hlth Res Ctr, Tehran, Iran.;Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran..
    Nayak, Vinod C.
    Manipal Acad Higher Educ, Dept Forens Med & Toxicol, Mangalore, India..
    Nazari, Javad
    Arak Univ Med Sci, Dept Pediat, Arak, Iran..
    Ndejjo, Rawlance
    Makerere Univ, Dis Control & Environm Hlth, Kampala, Uganda..
    Ndwandwe, Duduzile Edith
    South African Med Res Council, Cochrane South Africa, Cape Town, South Africa..
    Negoi, Ionut
    Carol Davila Univ Med & Pharm, Dept Gen Surg, Bucharest, Romania.;Emergency Hosp Bucharest, Dept Gen Surg, Bucharest, Romania..
    Negoi, Ruxandra Irina
    Carol Davila Univ Med & Pharm, Dept Anat & Embryol, Bucharest, Romania.;Cardio Aid, Bucharest, Romania..
    Netsere, Henok Biresaw
    Univ Gondar, Sch Nursing, Gondar, Ethiopia.;Bahir Dar Univ, Sch Hlth Sci, Dept Surg Nursing, Bahir Dar, Ethiopia..
    Neupane, Subas
    Univ Tampere, Dept Hlth Sci, Tampere, Finland..
    Ngari, Kiirithio N.
    Synotech Consultants, Res & Stat Unit, Nairobi, Kenya..
    Nguefack-Tsague, Georges
    Univ Yaounde I, Dept Publ Hlth, Yaounde, Cameroon..
    Ngunjiri, Josephine W.
    Univ Embu, Dept Biol Sci, Embu, Kenya..
    Nguyen, Cuong Tat
    Duy Tan Univ, Inst Global Hlth Innovat, Da Nang, Vietnam..
    Nguyen, Diep Ngoc
    Duy Tan Univ, Inst Global Hlth Innovat, Da Nang, Vietnam.;Duy Tan Univ, Fac Pharm, Da Nang, Vietnam..
    Nguyen, Huong Lan Thi
    Duy Tan Univ, Inst Global Hlth Innovat, Da Nang, Vietnam..
    Nguyen, Jason
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Nguyen, Michele
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Oxford, Malaria Atlas Project, Oxford, England..
    Nguyen, Ming
    Nguyen, Trang Huyen
    Nguyen Tat Thanh Univ, Ctr Excellence Behav Med, Ho Chi Minh City, Vietnam..
    Nichols, Emma
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Nigatu, Dabere
    Nigatu, Yeshambel T.
    Bahir Dar Univ, Dept Reprod Hlth & Populat Studies, Bahir Dar, Ethiopia.;Ctr Addict & Mental Hlth, Inst Mental Hlth Policy Res, Toronto, ON, Canada.;Inst Clin Evaluat Sci, Dept Clin Epidemiol, Ottawa, ON, Canada..
    Nikbakhsh, Rajan
    Shahid Beheshti Univ Med Sci, Obes Res Ctr, Tehran, Iran..
    Nikpoor, Amin Reza
    Hormozgan Univ Med Sci, Bandar Abbas, Iran..
    Nixon, Molly R.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Nnaji, Chukwudi A.
    South African Med Res Council, Cape Town, South Africa.;Univ Cape Town, Sch Publ Hlth & Family Med, Cape Town, South Africa..
    Nomura, Shuhei
    Univ Tokyo, Dept Global Hlth Policy, Tokyo, Japan.;Keio Univ, Dept Hlth Policy & Management, Tokyo, Japan..
    Norheim, Ole F.
    Harvard Univ, Dept Global Hlth & Populat, Boston, MA 02115 USA.;Univ Bergen, Dept Global Publ Hlth & Primary Care, Bergen, Norway..
    Norrving, Bo
    Lund Univ, Dept Clin Sci, Malmö, Sweden..
    Noubiap, Jean Jacques
    Univ Adelaide, Ctr Heart Rhythm Disorders, Adelaide, SA, Australia..
    Motlagh, Soraya Nouraei
    Lorestan Univ Med Sci, Dept Publ Hlth, Khorramabad, Iran..
    Nowak, Christoph
    Karolinska Inst, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden..
    Nsoesie, Elaine Okanyene
    Boston Univ, Sch Publ Hlth, Dept Global Hlth, Boston, MA 02215 USA..
    Nunez-Samudio, Virginia
    Inst Med Sci, Unit Microbiol & Publ Hlth, Las Tablas, Panama.;Minist Hlth, Dept Publ Hlth, Herrera, Panama..
    Oancea, Bogdan
    Univ Bucharest, Adm & Econ Sci Dept, Bucharest, Romania..
    Odell, Christopher M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Ogbo, Felix Akpojene
    Western Sydney Univ, Translat Hlth Res Inst, Sydney, NSW, Australia..
    Oghenetega, Onome Bright
    Univ Ibadan, Dept Obstet & Gynecol, Ibadan, Nigeria..
    Oh, In-Hwan
    Kyung Hee Univ, Dept Prevent Med, Seoul, South Korea..
    Okunga, Emmanuel Wandera
    Minist Hlth, Dis Surveillance & Epidem Response, Nairobi, Kenya..
    Oladnabi, Morteza
    Golestan Univ Med Sci, Gorgan Congenital Malformat Res Ctr, Gorgan, Golestan, Iran..
    Olagunju, Andrew T.
    McMaster Univ, Dept Psychiat & Behav Neurosci, Hamilton, ON, Canada.;Univ Lagos, Dept Psychiat, Lagos, Nigeria..
    Olusanya, Bolajoko Olubukunola
    Ctr Healthy Start Initiat, Lagos, Nigeria..
    Olusanya, Jacob Olusegun
    Ctr Healthy Start Initiat, Lagos, Nigeria..
    Oluwasanu, Mojisola Morenike
    Univ Ibadan, Dept Hlth Promot & Educ, Ibadan, Nigeria..
    Bali, Ahmed Omar
    Univ Human Dev, Diplomacy & Publ Relat Dept, Sulaymaniyah, Iraq..
    Omer, Muktar Omer
    Jigjiga Univ, Dept Publ Hlth, Jijiga, Ethiopia..
    Ong, Kanyin L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Ong, Sokking
    Pantai Jerudong Specialist Ctr, Early Detect & Canc Prevent Serv, Bandar Seri Begawan, Brunei.;Pantai Jerudong Specialist Ctr, Bandar Seri Begawan, Brunei.;Minist Hlth, Noncommunicable Dis Prevent Unit, Bandar Seri Begawan, Brunei..
    Onwujekwe, Obinna E.
    Univ Nigeria Nsukka, Dept Pharmacol & Therapeut, Enugu, Nigeria..
    Oren, Eyal
    Univ Washington, Seattle, WA 98195 USA.;San Diego State Univ, Grad Sch Publ Hlth, San Diego, CA 92182 USA..
    Orji, Aislyn U.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Orpana, Heather M.
    Publ Hlth Agcy Canada, Subst Related Harms Div, Toronto, ON, Canada.;Univ Ottawa, Sch Epidemiol & Publ Hlth, Ottawa, ON, Canada..
    Ortega-Altamirano, Doris V.
    Natl Publ Hlth Inst, Hlth Syst Res Ctr, Cuernavaca, Morelos, Mexico..
    Ortiz, Alberto
    Autonomous Univ Madrid, Dept Med, Madrid, Spain.;Fdn Jimenez Diaz Univ Hosp, Inst Hlth Res, Dept Hypertens & Nephrol, Madrid, Spain..
    Osarenotor, Osayomwanbo
    Univ Benin, Dept Environm Management & Toxicol, Benin, Nigeria..
    Osei, Frank B.
    Univ Twente, Fac Geoinformat Sci & Earth Observat, Enschede, Netherlands.;Univ Energy & Nat Resources, Dept Math & Stat, Sunyani, Ghana..
    Ostojic, Sergej M.
    Univ Novi Sad, Biomed Sci, Novi Sad, Serbia..
    Ostroff, Samuel M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Oiu, Adrian O.
    Otstavnov, Nikita
    Moscow Inst Phys & Technol, Lab Publ Hlth Indicators Anal & Hlth Digitalizat, Dolgoprudnyi, Russia..
    Otstavnov, Stanislav S.
    Moscow Inst Phys & Technol, Lab Publ Hlth Indicators Anal & Hlth Digitalizat, Dolgoprudnyi, Russia.;Natl Res Univ Higher Sch Econ, Dept Project Management, Moscow, Russia. Jagadguru Sri Shivarathreeswara Acad Hlth Educ &, Dept Resp Med, Mysore, Karnataka, India..
    Overland, Simon
    Univ Bergen, Dept Psychosocial Sci, Bergen, Norway.;Norwegian Inst Publ Hlth, Div Mental & Phys Hlth, Bergen, Norway..
    Owolabi, Mayowa O.
    Univ Coll Hosp, Dept Med, Ibadan, Nigeria.;Univ Ibadan, Dept Med, Ibadan, Nigeria..
    Section, Mahesh P. A.
    Padubidri, Jagadish Rao
    Manipal Acad Higher Educ, Dept Forens Med, Mangalore, India..
    Pakhale, Smita
    Ottawa Hosp Res Inst, Dept Med, Ottawa, ON, Canada..
    Pakhare, Abhijit P.
    All India Inst Med Sci, Dept Community Med & Family Med, Bhopal, India..
    Pakshir, Keyvan
    Shiraz Univ Med Sci, Dept Parasitol & Mycol, Shiraz, Iran..
    Palladino, Raffaele
    Imperial Coll London, Dept Primary Care & Publ Hlth, London, England.;Univ Naples Federico II, Dept Publ Hlth, Naples, Italy..
    Pana, Adrian
    Bucharest Univ Econ Studies, Dept Stat & Econometr, Bucharest, Romania.;Ctr Hlth Outcomes & Evaluat, Dept Hlth Metr, Bucharest, Romania..
    Panda-Jonas, Songhomitra
    Heidelberg Univ, Dept Ophthalmol, Heidelberg, Germany..
    Pandey, Anamika
    Publ Hlth Fdn India, Dept Res, Gurugram, India..
    Pangaribuan, Helena Ullyartha
    Minist Hlth, Natl Inst Hlth Res & Dev, Jakarta, Indonesia..
    Park, Eun-Kee
    Kosin Univ, Dept Med Humanities & Social Med, Busan, South Korea..
    Park, James
    Harvard Univ, Dept Biostat, Boston, MA 02115 USA..
    Parmar, Priya G. Kumari
    Auckland Univ Technol, Dept Biostat & Epidemiol, Auckland, New Zealand.;Auckland Univ Technol, Natl Inst Stroke & Appl Neurosci, Auckland, New Zealand..
    Parry, Charles D. H.
    Stellenbosch Univ, Dept Psychiat, Cape Town, South Africa.;South African Med Res Council, Alcohol Tobacco & Other Drug Res Unit, Cape Town, South Africa..
    Pasovic, Maja
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Pasupula, Deepak Kumar
    Univ Pittsburgh, Med Ctr, Div Gen Internal Med, Pittsburgh, PA USA..
    Patel, Jenil R.
    Univ Arkansas Med Sci, Dept Epidemiol, Little Rock, AR 72205 USA..
    Patel, Sangram Kishor
    Populat Council, Dept Poverty Gender & Youth, New Delhi, India..
    Paternina-Caicedo, Angel J.
    Univ Sinu, Sch Med, Cartagena, Colombia..
    Pathak, Ashish
    Karolinska Inst, Dept Global Publ Hlth Hlth Syst & Policy HSP Med, Stockholm, Sweden.;RD Gardi Med Coll, Dept Pediat, Ujjain, Madhya Pradesh, India..
    Pathak, Mona
    Kalinga Inst Med Sci, Dept Res & Dev, Bhubaneswar, India..
    Patten, Scott B.
    Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada..
    Patton, George C.
    Univ Melbourne, Dept Paediat, Melbourne, Vic, Australia.;Murdoch Childrens Res Inst, Populat Hlth Theme, Melbourne, Vic, Australia..
    Paudel, Deepak
    Ludwig Maximilians Univ Munchen, Ctr Int Hlth, Munich, Germany.;Save Children, Hlth Nutr & HIV AIDS Program, Kathmandu, Nepal..
    Paudel, Sagun
    Publ Hlth Youth Soc Nepal, Pokhara, Nepal.;Publ Hlth Update, Pokhara, Nepal..
    Paulson, Katherine R.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Toroudi, Hamidreza Pazoki
    Iran Univ Med Sci, Dept Physiol, Tehran, Iran.;Iran Univ Med Sci, Physiol Res Ctr, Tehran, Iran..
    Pease, Spencer A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Peden, Amy E.
    Univ New South Wales, Sch Publ Hlth & Community Med, Sydney, NSW, Australia.;James Cook Univ, Coll Publ Hlth Med & Vet Sci, Douglas, Qld, Australia..
    Pennini, Alyssa
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Pepito, Veincent Christian Filipino
    Ateneo Manila Univ, Ctr Res & Innovat, Pasig, Philippines..
    Peprah, Emmanuel K.
    NYU, Sch Global Publ Hlth, New York, NY USA..
    Pereira, Alexandre
    Harvard Univ, Dept Genet, Boston, MA 02115 USA.;Univ Sao Paulo, Lab Genet & Mol Cardiol, Sao Paulo, Brazil..
    Pereira, David M.
    Univ Porto, Associated Lab Green Chem LAQV, Porto, Portugal..
    Pereira, Jeevan
    Yenepoya Med Coll, Dept Orthoped, Mangalore, India..
    Perico, Norberto
    Mario Negri Inst Pharmacol Res, Milan, Italy..
    Pescarini, Julia Moreira
    Fundacao Oswaldo Cruz, Ctr Integrat Data & Hlth Knowledge, Salvador, BA, Brazil..
    Pesudovs, Konrad
    Univ New South Wales, Sch Optometry & Vis Sci, Sydney, NSW, Australia..
    Pham, Hai Quang
    Duy Tan Univ, Inst Global Hlth Innovat, Da Nang, Vietnam..
    Phillips, Michael R.
    Columbia Univ, Dept Psychiat, New York, NY USA.;Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Shanghai, Peoples R China..
    Piccinelli, Cristiano
    City Hlth & Sci Univ Hosp Turin, SSD Epidemiol Screening, Turin, Italy..
    Pierce, Maxwell
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Pigott, David M.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Pilgrim, Thomas
    Univ Bern, Dept Cardiol, Bern, Switzerland..
    Pilz, Tessa M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Pinheiro, Marina
    Univ Porto, Dept Chem, Porto, Portugal..
    Piradov, Michael A.
    Res Ctr Neurol, Moscow, Russia..
    Pirsaheb, Meghdad
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Pishgar, Farhad
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran.;Univ Tehran Med Sci, Urooncol Res Ctr, Tehran, Iran..
    Plana-Ripoll, Oleguer
    Aarhus Univ, Natl Ctr Register Based Res, Aarhus, Denmark..
    Plass, Dietrich
    German Environm Agcy, Dept Environm Hyg, Dessau Rosslau, Germany..
    Pletcher, Martin
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Pokhrel, Khem Narayan
    Integrated Dev Fdn Nepal, HIV & Mental Hlth Dept, Kathmandu, Nepal..
    Polibin, Roman V.
    IM Sechenov First Moscow State Med Univ, Dept Epidemiol & Evidence Based Med, Moscow, Russia..
    Polinder, Suzanne
    Erasmus MC, Dept Publ Hlth, Rotterdam, Netherlands..
    Polkinghorne, Kevan R.
    Monash Univ, Dept Med, Melbourne, Vic, Australia..
    Pond, Constance Dimity
    Univ Newcastle, Discipline Gen Practice, Newcastle, NSW, Australia..
    Postma, Maarten J.
    Univ Groningen, Sch Business & Econ, Groningen, Netherlands.;Univ Groningen, Univ Med Ctr Groningen, Groningen, Netherlands..
    Pottoo, Faheem Hyder
    Imam Abdulrahman Bin Faisal Univ, Dept Pharmacol, Dammam, Saudi Arabia..
    Pourjafar, Hadi
    Alborz Univ Med Sci, Dietary Supplements & Probiot Res Ctr, Karaj, Iran.;Maragheh Univ Med Sci, Dept Nutr & Food Sci, Maragheh, Iran..
    Pourmalek, Farshad
    Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada..
    Kalhori, Reza Pourmirza
    Kermanshah Univ Med Sci, Dept Emergency Med, Kermanshah, Iran..
    Pourshams, Akram
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran..
    Poznanska, Anna
    Natl Inst Publ Hlth, Dept Populat Hlth Monitoring & Anal, Warsaw, Poland..
    Prada, Sergio I.
    ICESI Univ, Clin Res Ctr, Valle Lili Fdn, Cali, Colombia.;ICESI Univ, Ctr Studies Social Protect & Hlth Econ, Cali, Colombia..
    Prakash, Sanjay
    Smt BKS Med Inst & Res Ctr, Dept Neurol, Vadodara, India..
    Prakash, V.
    Charotar Univ Sci & Technol, Rita Patel Inst Physiotherapy, Anand, Gujarat, India..
    Prasad, Narayan
    Sanjay Gandhi Postgrad Inst Med Sci, Dept Nephrol, Lucknow, Uttar Pradesh, India..
    Preotescu, Liliana
    Carol Davila Univ Med & Pharm, Dept Infect Dis, Bucharest, Romania.;Natl Inst Infect Dis, Bucharest, Romania..
    Pribadi, Dimas Ria Angga
    Muhammadiyah Univ Surakarta, Dept Hlth Sci, Sukoharjo, Indonesia..
    Pupillo, Elisabetta
    Mario Negri Inst Pharmacol Res, Dept Neurosci, Milan, Italy..
    Quazi Syed, Zahiruddin
    Datta Meghe Inst Med Sci, Dept Community Med, Wardha, India..
    Rabiee, Mohammad
    Amirkabir Univ Technol, Dept Biomed Engn, Tehran, Iran..
    Rabiee, Navid
    Sharif Univ Technol, Dept Chem, Tehran, Iran..
    Radfar, Amir
    Univ Cent Florida, Coll Med, Orlando, FL 32816 USA..
    Rafiee, Ata
    Univ Alberta, Dept Med, Edmonton, AB, Canada..
    Rafiei, Alireza
    Mazandaran Univ Med Sci, Dept Immunol, Sari, Iran.;Mazandaran Univ Med Sci, Mol & Cell Biol Res Ctr, Sari, Iran..
    Raggi, Alberto
    Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy..
    Rahim, Fakher
    Univ Tehran Med Sci, Metabol & Genom Res Ctr, Tehran, Iran.;Ahvaz Jundishapur Univ Med Sci, Thalassemia & Hemoglobinopathy Res Ctr, Ahwaz, Iran..
    Rahimi-Movaghar, Afarin
    Univ Tehran Med Sci, Iranian Natl Ctr Addict Studies INCAS, Tehran, Iran..
    Rahman, Mohammad Hifz Ur
    La Trobe Univ, Sch Nursing & Midwifery, Melbourne, Vic, Australia.;Maharishi Markandeshwar Inst Med Sci & Res, Dept Community Med, Ambala, India..
    Rahman, Muhammad Aziz
    Federat Univ Australia, Sch Nursing & Healthcare Profess, Berwick, Vic, Australia..
    Rajabpour-Sanati, Ali
    Birjand Univ Med Sci, Fac Med, Birjand, Iran..
    Rajati, Fatemeh
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Rakovac, Ivo
    World Hlth Org WHO, European Off Prevent & Control Noncommunicable Di, Geneva, Switzerland..
    Ram, Pradhum
    Emory Univ, Div Cardiol, Atlanta, GA 30322 USA..
    Ramezanzadeh, Kiana
    Shahid Beheshti Univ Med Sci, Sch Pharm, Tehran, Iran..
    Rana, Saleem Muhammad
    Univ Lahore, Univ Inst Publ Hlth, Lahore, Pakistan.;Univ Hlth Sci, Dept Publ Hlth, Lahore, Pakistan..
    Ranabhat, Chhabi Lal
    Policy Res Inst, Res Dept, Kathmandu, Nepal.;Global Ctr Res & Dev, Hlth & Publ Policy Dept, Kathmandu, Nepal..
    Ranta, Annemarei
    Univ Otago, Dept Med, Wellington, New Zealand.;Capital & Coast Dist Hlth Board, Dept Neurol, Wellington, New Zealand..
    Rao, Puja C.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Rao, Sowmya J.
    Srinivas Inst Dent Sci, Dept Oral Pathol, Mangalore, India..
    Rasella, Davide
    Univ Fed Bahia, Inst Collect Hlth, Salvador, BA, Brazil..
    Rashedi, Vahid
    Iran Univ Med Sci, Tehran Inst Psychiat, Tehran, Iran..
    Rastogi, Prateek
    Manipal Acad Higher Educ, Dept Forens Med & Toxicol, Mangalore, India..
    Rath, Goura Kishor
    All India Inst Med Sci, Dept Radiat Oncol, New Delhi, India.;All India Inst Med Sci, Dept Radiat Oncol, New Delhi, India..
    Rathi, Priya
    Manipal Acad Higher Educ, Kasturba Med Coll, Mangalore, India..
    Rawaf, David Laith
    Imperial Coll London, WHO Collaborating Ctr Publ Hlth Educ & Training, London, England.;Univ Coll London Hosp, London, England..
    Rawaf, Salman
    Imperial Coll London, Dept Primary Care & Publ Hlth, London, England.;Publ Hlth England, Acad Publ Hlth England, London, England.;Publ Hlth England, Acad Publ Hlth England, London, England..
    Rawal, Lal
    CQ Univ, Sch Hlth Med & Appl Sci, Sydney, NSW, Australia..
    Rawassizadeh, Reza
    Boston Univ, Dept Comp Sci, Boston, MA 02215 USA..
    Rawat, Ramu
    Int Inst Populat Sci, Dept Math Demog & Stat, Mumbai, Maharashtra, India..
    Razo, Christian
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Boston, Sofia
    Regassa, Lemma Demissie
    Haramaya Univ, Sch Publ Hlth, Harar, Ethiopia..
    Reiner, Robert C., Jr.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Reinig, Nickolas
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Reitsma, Marissa Bettay
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Remuzzi, Giuseppe
    Mario Negri Inst Pharmacol Res, Milan, Italy..
    Renjith, Vishnu
    Royal Coll Surg Ireland Bahrain, Sch Nursing & Midwifery, Muharraq Governorate, Bahrain..
    Renzaho, Andre M. N.
    Western Sydney Univ, Sch Social Sci & Psychol, Sydney, Vic, Australia.;Western Sydney Univ, Translat Hlth Res Inst, Sydney, NSW, Australia..
    Resnikoff, Serge
    Univ New South Wales, Sch Optometry & Vis Sci, Sydney, NSW, Australia.;Brien Holden Vis Inst, Sydney, NSW, Australia..
    Rezaei, Negar
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran.;Univ Tehran Med Sci, Res Ctr Immunodeficiencies, Tehran, Iran.;Univ Sci Educ & Res Network USERN, Network Immun Infect Malignancy & Autoimmun NIIMA, Tehran, Iran..
    Rezaei, Nima
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran..
    Rezai, Mohammad Sadegh
    Mazandaran Univ Med Sci, Pediat Infect Dis Res Ctr, Sari, Iran..
    Rezapour, Aziz
    Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, Iran..
    Rhinehart, Phoebe-Anne
    Riahi, Seyed Mohammad
    Birjand Univ Med Sci, Cardiovasc Dis Res Ctr, Birjand, Iran..
    Ribeiro, Antonio Luiz P.
    Univ Fed Minas Gerais, Ctr Telehlth, Belo Horizonte, MG, Brazil.;Univ Fed Minas Gerais, Dept Internal Med, Belo Horizonte, MG, Brazil..
    Ribeiro, Daniel Cury
    Univ Otago, Sch Physiotherapy, Wellington, New Zealand..
    Ribeiro, Daniela
    Univ Porto, Dept Chem Sci, Porto, Portugal..
    Rickard, Jennifer
    Univ Minnesota, Dept Surg, Box 242 UMHC, Minneapolis, MN 55455 USA.;Univ Teaching Hosp Kigali, Dept Surg, Kigali, Rwanda..
    Rivera, Juan A.
    Natl Inst Publ Hlth, Hlth & Nutr Res Ctr, Cuernavaca, Morelos, Mexico..
    Robalik, Toshana
    Roberts, Nicholas L. S.
    Roberts, Shaun
    Auckland Univ Technol, Natl Inst Stroke & Appl Neurosci, Auckland, New Zealand..
    Robinson, Stephen R.
    RMIT Univ, Dept Psychol, Melbourne, Vic, Australia..
    Rodriguez-Ramirez, Sonia
    Natl Inst Publ Hlth, Ctr Nutr & Hlth Res, Cuernavaca, Morelos, Mexico..
    Roever, Leonardo
    Univ Fed Uberlandia, Dept Clin Res, Uberlandia, MG, Brazil..
    Rolfe, Sam
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Romoli, Michele
    Univ Perugia, Dept Neurosci, Perugia, Italy.;Rimini Infermi Hosp AUSL Romagna, Dept Neurol, Rimini, Italy..
    Ronfani, Luca
    Burlo Garofolo Inst Maternal & Child Hlth, Clin Epidemiol & Publ Hlth Res Unit, Trieste, Italy..
    Room, Robin
    La Trobe Univ, Ctr Alcohol Policy Res CAPR, Melbourne, Vic, Australia.;Stockholm Univ, Ctr Social Res Alcohol & Drugs, Stockholm, Sweden..
    Roshandel, Gholamreza
    Golestan Univ Med Sci, Golestan Res Ctr Gastroenterol & Hepatol GRCGH, Gorgan, Golestan, Iran..
    Rostamian, Morteza
    Gonabad Univ Med Sci, Sch Med, Gonabad, Iran..
    Roth, Gregory A.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Div Cardiol, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Rothenbacher, Dietrich
    Ulm Univ, Inst Epidemiol & Med Biometry, Ulm, Germany..
    Rubagotti, Enrico
    Agrosavia, Palmira, Colombia..
    Rumisha, Susan Fred
    Univ Oxford, Malaria Atlas Project, Oxford, England.;Natl Inst Med Res, Dept Hlth Stat, Dar Es Salaam, Tanzania..
    Rwegerera, Godfrey M.
    Univ Botswana, Dept Internal Med, Gaborone, Botswana..
    Saadatagah, Seyedmohammad
    Mayo Clin, Dept Cardiovasc Med, Rochester, MN USA..
    Sabour, Siamak
    Shahid Beheshti Univ Med Sci, Dept Epidemiol, Tehran, Iran..
    Sachdev, Perminder S.
    Univ New South Wales, Sch Psychiat, Sydney, NSW, Australia.;Prince Wales Hosp, Neuropsychiat Inst, Randwick, NSW, Australia..
    Saddik, Basema
    Univ Sharjah, Dept Family & Community Med, Sharjah, U Arab Emirates..
    Sadeghi, Ehsan
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Sadeghi, Masoumeh
    Isfahan Univ Med Sci, Cardiac Rehabil Res Ctr, Esfahan, Iran..
    Saeedi, Reza
    Shahid Beheshti Univ Med Sci, Dept Hlth Safety & Environm HSE, Tehran, Iran..
    Moghaddam, Sahar Saeedi
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran..
    Saeidi, Shahram
    Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran..
    Safari, Yahya
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Safi, Sare
    Shahid Beheshti Univ Med Sci, Ophthalm Epidemiol Res Ctr, Tehran, Iran.;Shahid Beheshti Univ Med Sci, Ophthalm Res Ctr, Tehran, Iran..
    Safiri, Saeid
    Tabriz Univ Med Sci, Aging Res Inst, Tabriz, Iran.;Tabriz Univ Med Sci, Dept Community Med, Tabriz, Iran..
    Sagar, Rajesh
    All India Inst Med Sci, Dept Psychiat, New Delhi, India..
    Sahebkar, Amirhossein
    Mashhad Univ Med Sci, Neurogen Inflammat Res Ctr, Mashhad, Razavi Khorasan, Iran.;Food & Drug Adm Islamic Republ Iran, Halal Res Ctr IRI, Tehran, Iran..
    Sahraian, Mohammad Ali
    Univ Tehran Med Sci, Multiple Sclerosis Res Ctr, Tehran, Iran..
    Sajadi, S. Mohammad
    Soran Univ, Dept Phytochem, Soran, Iraq.;Cihan Univ Erbil, Dept Nutr, Kurdistan Region, Iraq..
    Salahshoor, Mohammad Reza
    Kermanshah Univ Med Sci, Dept Anat Sci, Kermanshah, Iran..
    Salam, Nasir
    Cent Univ Punjab, Dept Microbiol, Bathinda, India..
    Salama, Joseph S.
    Univ Calif San Francisco, Hlth Hub, San Francisco, CA 94143 USA..
    Salamati, Payman
    Univ Tehran Med Sci, Sina Trauma & Surg Res Ctr, Tehran, Iran..
    Zahabi, Saleh Salehi
    Kermanshah Univ Med Sci, Dept Radiol & Nucl Med, Kermanshah, Iran.;Taleghani Hosp, Res Dept, Kermanshah, Iran..
    Salem, Hosni
    Cairo Univ, Dept Urol, Cairo, Egypt..
    Salem, Marwa R.
    Cairo Univ, Publ Hlth & Community Med Dept, Cairo, Egypt..
    Salimi, Yahya
    Kermanshah Univ Med Sci, Dept Epidemiol & Biostat, Kermanshah, Iran.;Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran..
    Salimzadeh, Hamideh
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran..
    Salman, Omar Mukhtar
    London Sch Hyg & Trop Med, Dept Global Hlth & Dev, London, England.;Amer Univ Beirut, Global Hlth Inst, Beirut, Lebanon..
    Salomon, Joshua A.
    Stanford Univ, Ctr Hlth Policy, Stanford, CA 94305 USA.;Stanford Univ, Ctr Primary Care & Outcomes Res, Stanford, CA 94305 USA..
    Salz, Inbal
    Minist Hlth, Hlth & Disabil Intelligence Grp, Wellington, New Zealand..
    Samad, Zainab
    Duke Univ, Dept Med, Durham, NC USA..
    Kafil, Hossein Samadi
    Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran..
    Sambala, Evanson Zondani
    South African Med Res Council, Cape Town, South Africa..
    Samy, Abdallah M.
    Ain Shams Univ, Dept Entomol, Cairo, Egypt..
    Sanabria, Juan
    Case Western Reserve Univ, Dept Nutr & Prevent Med, Cleveland, OH 44106 USA.;Marshall Univ, Dept Surg, Huntington, WV USA..
    Sanchez-Pimienta, Tania G.
    Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico..
    Santomauro, Damian Francesco
    Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia.;Queensland Ctr Mental Hlth Res, West Moreton Hosp Hlth Serv, Brisbane, Qld, Australia..
    Santos, Itamar S.
    Univ Sao Paulo, Ctr Clin & Epidemiol Res, Sao Paulo, Brazil.;Univ Sao Paulo, Dept Internal Med, Sao Paulo, Brazil..
    Santos, Joao Vasco
    Univ Porto, Ctr Hlth Technol & Serv Res, Porto, Portugal.;Northern Reg Hlth Adm, ACES Grande Porto VIII Espinho Gaia, Publ Hlth Unit, Vila Nova De Gaia, Portugal..
    Santric-Milicevic, Milena M.
    Univ Belgrade, Fac Med, Belgrade, Serbia.;Univ Belgrade, Sch Publ Hlth & Hlth Management, Belgrade, Serbia..
    Saraswathy, Sivan Yegnanarayana Iyer
    PSG Inst Med Sci & Res, Dept Community Med, Coimbatore, Tamil Nadu, India.;PSG FAIMER South Asia Reg Inst, Coimbatore, Tamil Nadu, India..
    Sarmiento-Suarez, Rodrigo
    Univ Appl & Environm Sci, Fac Med, Bogota, Colombia.;Carlos III Hlth Inst, Natl Sch Publ Hlth, Madrid, Spain..
    Sarrafzadegan, Nizal
    Isfahan Univ Med Sci, Isfahan Cardiovasc Res Inst, Esfahan, Iran.;Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada..
    Sartorius, Benn
    London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England.;Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA..
    Sarveazad, Arash
    Iran Univ Med Sci, Colorectal Res Ctr, Tehran, Iran..
    Sathian, Brijesh
    Hamad Med Corp, Dept Geriatr & Long Term Care, Doha, Qatar.;Bournemouth Univ, Fac Hlth & Social Sci, Bournemouth, Dorset, England..
    Sathish, Thirunavukkarasu
    McMaster Univ, Populat Hlth Res Inst, Hamilton, ON, Canada..
    Sattin, Davide
    Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy..
    Savic, Miloje
    GSK Biol, Wavre, Belgium..
    Sawyer, Susan M.
    Univ Melbourne, Dept Paediat, Melbourne, Vic, Australia.;Murdoch Childrens Res Inst, Ctr Adolescent Hlth, Melbourne, Vic, Australia..
    Saxena, Deepak
    Datta Meghe Inst Med Sci, Dept Community Med, Wardha, India.;Indian Inst Publ Hlth, Dept Epidemiol, Gandhinagar, India..
    Saxena, Sonia
    Imperial Coll London, Sch Publ Hlth, London, England..
    Saylan, Mete
    Bayer, Market Access, Istanbul, Turkey..
    Sbarra, Alyssa N.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Schaeffer, Lauren E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Schiavolin, Silvia
    Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy..
    Schlaich, Markus P.
    Univ Western Australia, Dobney Hypertens Ctr, Perth, WA, Australia.;Baker Heart & Diabet Inst, Hypertens & Kidney Dis Lab, Melbourne, Vic, Australia..
    Schmidt, Maria Ines
    Univ Fed Rio Grande do Sul, Postgrad Program Epidemiol, Porto Alegre, RS, Brazil..
    Schutte, Aletta Elisabeth
    Univ New South Wales, Sydney, NSW, Australia. George Inst Global Hlth, Sydney, NSW, Australia.;North West Univ, Unit Hypertens & Cardiovasc Dis, Potchefstroom, South Africa..
    Schwebel, David C.
    Univ Alabama Birmingham, Dept Psychol, Birmingham, AL 35294 USA..
    Schwendicke, Falk
    Charite Univ Med Ctr Berlin, Oral Diag Digital Hlth & Hlth Serv Res, Berlin, Germany..
    Seedat, Soraya
    Stellenbosch Univ, Dept Psychiat, Cape Town, South Africa..
    Sekerija, Mario
    Univ Zagreb, Dept Med Stat Epidemiol & Med Informat, Zagreb, Croatia.;Croatian Inst Publ Hlth, Dept Epidemiol & Prevent Chron Noncommunicable Di, Zagreb, Croatia..
    Senbeta, Anbissa Muleta
    Jigjiga Univ, Dept Food Sci & Nutr, Jijiga, Ethiopia..
    Senthilkumaran, Subramanian
    Manian Med Ctr, Emergency Dept, Erode, India..
    Sepanlou, Sadaf G.
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran.;Shiraz Univ Med Sci, Noncommunicable Dis Res Ctr, Shiraz, Iran..
    Serdar, Berrin
    Univ Colorado Denver, Sch Publ Hlth, Aurora, CO USA.;Environm Hlth Associates LLC, Englewood, CO USA..
    Serre, Marc L.
    Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27515 USA..
    Servan-Mori, Edson
    Natl Inst Publ Hlth, Ctr Hlth Syst Res, Cuernavaca, Morelos, Mexico..
    Sha, Feng
    Shenzhen Inst Adv Technol, Ctr Biomed Informat Technol, Shenzhen, Peoples R China..
    Shabani, Mahsima
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran.;Johns Hopkins Univ, Dept Cardiol, Baltimore, MD USA..
    Shackelford, Katya Anne
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Shadid, Jamileh
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia..
    Shafaat, Omid
    Johns Hopkins Univ, Dept Radiol & Radiol Sci, Baltimore, MD USA..
    Shahabi, Saeed
    Shiraz Univ Med Sci, Ctr Hlth Policy Res, Shiraz, Iran..
    Shahbaz, Mohammad
    Shahid Beheshti Univ Med Sci, Dept Epidemiol, Tehran, Iran..
    Shaheen, Amira A.
    An Najah Natl Univ, Publ Hlth Div, Nablus, Palestine..
    Shaikh, Masood Ali
    Shalash, Ali S.
    Ain Shams Univ, Dept Neurol, Cairo, Egypt..
    Shams-Beyranvand, Mehran
    Alborz Univ Med Sci, Sch Med, Karaj, Iran..
    Shamsi, MohammadBagher
    Kermanshah Univ Med Sci, Dept Rehabil & Sports Med, Kermanshah, Iran..
    Shamsizadeh, Morteza
    Univ Borås, Fac Caring Sci Work Life & Social Welf, Borås, Sweden..
    Shannawaz, Mohammed
    BLDE Univ, Dept Community Med, Vijayapur, India..
    Sharafi, Kiomars
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Sharafi, Zeinab
    Lorestan Univ Med Sci, Razi Herbal Med Res Ctr, Khorramabad, Iran..
    Sharara, Fablina
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Sharifi, Hamid
    Kerman Univ Med Sci, HIV STI Surveillance Res Ctr & WHO Collaborating, Kerman, Iran..
    Sharma, Rajesh
    Delhi Technol Univ, Univ Sch Management & Entrepreneurship, Delhi, India..
    Shaw, David H.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Sheena, Brittney S.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Sheikh, Aziz
    Harvard Univ, Div Gen Internal Med, Boston, MA 02115 USA.;Univ Edinburgh, Med Informat Ctr, Edinburgh, Midlothian, Scotland..
    Sheikhtaheri, Abbas
    Iran Univ Med Sci, Hlth Informat Management, Tehran, Iran..
    Shetty, B. Suresh Kumar
    Publ Hlth Fdn India, Gurugram, India..
    Shetty, Ranjitha S.
    Manipal Acad Higher Educ, Dept Community Med, Mangalore, India.;Manipal Acad Higher Educ, Dept Forens Med & Toxicol, Mangalore, India..
    Shibuya, Kenji
    Kings Coll London, Inst Populat Hlth, London, England..
    Shield, Kevin David
    Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada.;Ctr Addict & Mental Hlth, Inst Mental Hlth Policy Res, Toronto, ON, Canada..
    Shiferaw, Wondimeneh Shibabaw
    Debre Berhan Univ, Dept Nursing, Debre Berhan, Ethiopia..
    Shigematsu, Mika
    Natl Inst Infect Dis, Bucharest, Romania..
    Il Shin, Jae
    Yonsei Univ, Coll Med, Seoul, South Korea..
    Shin, Min-Jeong
    Korea Univ, Seoul, South Korea..
    Shiri, Rahman
    Finnish Inst Occupat Hlth, Helsinki, Finland..
    Shirkoohi, Reza
    Univ Tehran Med Sci, Canc Biol Res Ctr, Tehran, Iran.;Univ Tehran Med Sci, Canc Res Inst, Tehran, Iran..
    Shivakumar, K. M.
    Krishna Inst Med Sci, Fac Dent Sci, Karad, India..
    Shrime, Mark G.
    Harvard Univ, Boston, MA 02115 USA..
    Shuval, Kerem
    Univ Haifa, Sch Publ Hlth, Haifa, Israel..
    Siabani, Soraya
    Kermanshah Univ Med Sci, Dept Hlth Educ & Hlth Promot, Kermanshah, Iran.;Univ Technol Sydney, Sch Hlth, Sydney, NSW, Australia..
    Sierpinski, Radoslaw
    Med Res Agcy, Warsaw, Poland.;Cardinal Wyszynski Univ, Sch Med, Warsaw, Poland..
    Sigfusdottir, Inga Dora
    Columbia Univ, Dept Hlth & Behav Studies, New York, NY USA.;Reykjavik Univ, Dept Psychol, Reykjavik, Iceland..
    Sigurvinsdottir, Rannveig
    Reykjavik Univ, Dept Psychol, Reykjavik, Iceland..
    Silva, Diego Augusto Santos
    Univ Fed Santa Catarina, Dept Phys Educ, Florianopolis, SC, Brazil..
    Silva, Joao Pedro
    Univ Porto, Res Unit Appl Mol Biosci UCIBIO, Porto, Portugal..
    Simonetti, Biagio
    Univ Sannio, Dept Law Econ Management & Quantitat Methods, Benevento, Italy.;WSB Univ, Gdansk, Poland..
    Simpson, Kyle E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Singh, Ambrish
    Univ Tasmania, Menzies Inst Med Res, Hobart, Tas, Australia.;Eli Lilly & Co, Global Patient Outcome & Real World Evidence, Indianapolis, IN 46285 USA..
    Singh, Jasvinder A.
    Univ Alabama Birmingham, Sch Med, Birmingham, AL USA.;US Dept Vet Affairs VA, Med Serv, Birmingham, AL USA..
    Singh, Pushpendra
    Indian Inst Technol, Dept Humanities & Social Sci, Roorkee, Uttar Pradesh, India..
    Sinha, Dhirendra Narain
    Sch Prevent Oncol, Dept Epidemiol, Patna, Bihar, India.;Healis Sekhsaria Inst Publ Hlth, Dept Epidemiol, Mumbai, Maharashtra, India..
    Skiadaresi, Eirini
    Hywel Dda Univ Hlth Board, Dept Ophthalmol, Llanelli, Wales..
    Skou, Soren T.
    Univ Southern Denmark, Dept Sports Sci & Clin Biomech, Odense, Denmark.;Naestved Slagelse Ringsted Hosp, Dept Physiotherapy & Occupat Therapy, Slagelse, Denmark..
    Skryabin, Valentin Yurievich
    Moscow Res & Pract Ctr Addict, Dept 16, Moscow, Russia..
    Sliwa, Karen
    Univ Cape Town, Hatter Inst Dept Med, Cape Town, South Africa..
    Smith, Amanda
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Smith, Emma U. R.
    Univ Sydney, Inst Bone & Joint Res, Sydney, NSW, Australia.;Univ Sydney, Pain Management Res Inst PMRI, Sydney, NSW, Australia..
    Sobngwi, Eugene
    Univ Yaounde I, Dept Internal Med & Specialties, Yaounde, Cameroon.;Yaounde Cent Hosp, Dept Endocrinol & Diabet, Yaounde, Cameroon..
    Soheili, Amin
    Semnan Univ Med Sci, Nursing Care Res Ctr, Semnan, Iran..
    Sokhan, Anton
    Kharkiv Natl Med Univ, Dept Infect Dis, Kharkiv, Ukraine..
    Soltani, Shahin
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Somefun, Oluwaseyi Dolapo
    Univ Witwatersrand, Demog & Populat Studies Dept, Johannesburg, South Africa..
    Soofi, Moslem
    Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran..
    Sorensen, Reed J. D.
    Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Soriano, Joan B.
    Autonomous Univ Madrid, Princess Univ Hosp, Madrid, Spain.;Ctr Invest Biomed Red Enfermedades Resp CIBERES, Madrid, Spain..
    Sorrie, Muluken Bekele
    Arba Minch Univ, Dept Publ Hlth, Arba Minch, Ethiopia..
    Soshnikov, Sergey
    Moscow Inst Phys & Technol, Lab Publ Hlth Indicators Anal & Hlth Digitalizat, Dolgoprudnyi, Russia.;Minist Hlth FRIHOI, Fed Res Inst Hlth Org & Informat, Res Dev Dept, Moscow, Russia..
    Soyiri, Ireneous N.
    Univ Hull, Hull York Med Sch, Kingston Upon Hull, N Humberside, England..
    Spencer, Cory N.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Spotin, Adel
    Tabriz Univ Med Sci, Dept Parasitol & Mycol, Tabriz, Iran..
    Spurlock, Emma Elizabeth
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Sreeramareddy, Chandrashekhar T.
    Int Med Univ, Div Community Med, Kuala Lumpur, Malaysia..
    Srinivasan, Vinay
    Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA..
    Sripada, Kam
    Norwegian Univ Sci & Technol, Ctr Global Hlth Inequal Res CHAIN, Trondheim, Norway..
    Stanaway, Jeffrey D.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Stark, Benjamin A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Steel, Nicholas
    Publ Hlth England, London, England.;Univ East Anglia, Dept Primary Care & Publ Hlth, Norwich, Norfolk, England..
    Stefan, Simona Catalina
    Bucharest Univ Econ Studies, Dept Management, Bucharest, Romania..
    Stein, Caroline
    Univ Fed Rio Grande do Sul, Postgrad Program Epidemiol, Porto Alegre, RS, Brazil..
    Stein, Dan J.
    South African Med Res Council, Risk & Resilience Mental Disorders Res Unit, Cape Town, South Africa..
    Steiner, Caitlyn
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Steiner, Timothy J.
    Imperial Coll London, Div Brain Sci, London, England.;Norwegian Univ Sci & Technol, Dept Neuromed & Movement Sci, Trondheim, Norway..
    Steuben, Krista M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Stockfelt, Leo
    Univ Gothenburg, Occupat & Environm Med Dept, Gothenburg, Sweden..
    Stokes, Mark A.
    Deakin Univ, Dept Psychol, Burwood, Vic, Australia..
    Stovner, Lars Jacob
    Norwegian Univ Sci & Technol, Dept Neuromed & Movement Sci, Trondheim, Norway.;St Olavs Hosp, Dept Neurol & Clin Neurophysiol, Trondheim, Norway..
    Straif, Kurt
    Boston Coll, Schiller Inst, Boston, MA USA..
    Stranges, Saverio
    Univ Western Ontario, Dept Epidemiol & Biostat, London, ON, Canada.;Luxembourg Inst Hlth, Dept Populat Hlth, Strassen, Luxembourg..
    Stubbs, Jacob L.
    Univ British Columbia, Dept Psychiat, Vancouver, BC, Canada..
    Suchdev, Parminder S.
    Emory Univ, Dept Pediat, Atlanta, GA 30322 USA..
    Sudaryanto, Agus
    Muhammadiyah Univ Surakarta, Dept Nursing, Sukoharjo, Indonesia..
    Sufiyan, Mu'awiyyah Babale
    Ahmadu Bello Univ, Dept Community Med, Zaria, Nigeria..
    Suleria, Hafiz Ansar Rasul
    Univ Melbourne, Dept Agr & Food Syst, Melbourne, Vic, Australia..
    Abdulkader, Rizwan Suliankatchi
    Indian Council Med Res, Natl Inst Epidemiol, New Delhi, India.;Manonmaniam Sundaranar Univ, Dept Stat, Tirunelveli, India..
    Sulo, Gerhard
    Norwegian Inst Publ Hlth, Bergen, Norway..
    Sultan, Iyad
    King Hussein Canc Ctr, Serv Pediat, Amman, Jordan.;Univ Jordan, Dept Pediat, Amman, Jordan..
    Swope, Carolyn B.
    Delos Living, Delos Labs, New York, NY USA..
    Sykes, Bryan L.
    Univ Calif Irvine, Dept Criminol Law & Soc, Irvine, CA USA..
    Sylte, Dillon O.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Szocska, Miklos
    Semmelweis Univ, Fac Hlth & Publ Adm, Budapest, Hungary..
    Szumowski, Lukasz
    Inst Cardiol Poland, Minister Hlth, Warsaw, Poland..
    Tabares-Seisdedos, Rafael
    Biomed Res Networking Ctr Mental Hlth Network Cib, Carlos III Hlth Inst, Barcelona, Spain.;Univ Valencia, Dept Med, Valencia, Spain..
    Tabb, Karen M.
    Univ Illinois, Sch Social Work, Urbana, IL 61801 USA..
    Tabuchi, Takahiro
    Osaka Int Canc Inst, Canc Control Ctr, Osaka, Japan..
    Tadakamadla, Santosh Kumar
    Griffith Univ, Sch Dent & Oral Hlth, Nathan, Qld, Australia..
    Taddele, Biruk Wogayehu
    Arbaminch Coll Hlth Sci, Dept Pharm, Arbaminch, Ethiopia..
    Tadesse, Degena Bahrey
    Aksum Univ, Dept Nursing, Aksum, Ethiopia..
    Taherkhani, Amir
    Hamadan Univ Med Sci, Res Ctr Mol Med, Hamadan, Iran..
    Tahir, Zarfishan
    Inst Publ Hlth, Lahore, Pakistan..
    Tajdini, Masih
    Univ Tehran Med Sci, Tehran Heart Ctr, Tehran, Iran..
    Takahashi, Ken
    Asbestos Dis Res Inst, Concord, NSW, Australia..
    Takala, Jukka S.
    Univ Tampere, Dept Hlth Sci, Tampere, Finland.;Monteporzio Catone, Int Comion Occupat Hlth, Rome, Italy..
    Tamiru, Animut Tagele
    Univ Gondar, Dept Midwifery, Gondar, Ethiopia..
    Tang, Muming
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Tanser, Frank C.
    Africa Hlth Res Inst, Berea, South Africa..
    Tareque, Md Ismail
    Univ Rajshahi, Dept Populat Sci & Human Resource Dev, Rajshahi, Bangladesh..
    Tarigan, Ingan Ukur
    Natl Inst Hlth Res Dev, Res & Dev Ctr Humanities & Hlth Management, Jakarta, Indonesia..
    Taveira, Nuno
    Univ Inst Egas Moniz, Monte De Caparica, Portugal.;Univ Lisbon, Res Inst Med, Lisbon, Portugal..
    Taylor, Heather Jean
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Teagle, Whitney L.
    NIH, NEI, Bldg 10, Bethesda, MD 20892 USA..
    Teame, Hirut
    Adigrat Univ, Dept Publ Hlth, Adigrat, Ethiopia..
    Tediosi, Fabrizio
    Univ Basel, Basel, Switzerland..
    Tefera, Yonas Getaye
    Univ Gondar, Dept Clin Pharm, Gondar, Ethiopia..
    Tehrani-Banihashemi, Arash
    Iran Univ Med Sci, Dept Community & Family Med, Tehran, Iran.;Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran..
    Teklehaimanot, Berhane Fseha
    Adigrat Univ, Dept Publ Hlth, Adigrat, Ethiopia..
    Tela, Freweini Gebrearegay
    Mekelle Univ, Sch Publ Hlth, Mekelle, Ethiopia..
    Temsah, Mohamad-Hani
    King Saud Univ, Pediat Intens Care Unit, Riyadh, Saudi Arabia..
    Terrason, Sonyah
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Tesema, Getayeneh Antehunegn
    Univ Gondar, Dept Epidemiol & Biostat, Gondar, Ethiopia..
    Tessema, Zemenu Tadesse
    Univ Gondar, Dept Epidemiol & Biostat, Gondar, Ethiopia..
    Thakur, Bhaskar
    Harvard Univ, Massachusetts Vet Epidemiol Res & Informat Ctr MA, Boston, MA 02115 USA.;Texas Tech Univ, Div Biostat & Epidemiol, El Paso, TX USA..
    Thankappan, Kavumpurathu Raman
    Cent Univ Kerala, Dept Publ Hlth & Community Med, Kasaragod, India..
    Thapar, Rekha
    Manipal Acad Higher Educ, Dept Community Med, Mangalore, India..
    Thomas, Nihal
    Christian Med Coll & Hosp CMC, Dept Endocrinol Diabet & Metab, Vellore, India..
    Thomson, Azalea M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Thrift, Amanda G.
    Monash Univ, Dept Med, Melbourne, Vic, Australia..
    Thurston, George D.
    NYU, Dept Environm Med, 550 1St Ave, New York, NY 10016 USA..
    Titova, Mariya Vladimirovna
    Moscow Inst Phys & Technol, Lab Publ Hlth Indicators Anal & Hlth Digitalizat, Dolgoprudnyi, Russia.;Russian Acad Sci, Timiryazev Inst Plant Physiol, Moscow, Russia..
    Tlou, Boikhutso
    Univ KwaZulu Natal, Discipline Publ Hlth Med, Durban, South Africa..
    Tohidinik, Hamid Reza
    Univ Tehran Med Sci, Dept Epidemiol & Biostat, Tehran, Iran.;Kerman Univ Med Sci, HIV STI Surveillance Res Ctr & WHO Collaborating, Kerman, Iran..
    Tonelli, Marcello
    Univ Calgary, Dept Med, Calgary, AB, Canada..
    Topor-Madry, Roman
    Jagiellonian Univ, Coll Med, Inst Publ Hlth, Krakow, Poland.;Agcy Hlth Technol Assessment & Tariff Syst, Warsaw, Poland..
    Topouzis, Fotis
    Aristotle Univ Thessaloniki, Dept Ophthalmol 1, Thessaloniki, Greece..
    Torre, Anna E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Touvier, Mathilde
    Natl Inst Hlth & Med Res INSERM, Nutrit Epidemiol Res Team EREN, Paris, France.;Sorbonne Paris Nord Univ, Hlth Med & Human Biol, Bobigny, France..
    Tovani-Palone, Marcos Roberto
    Univ Sao Paulo, Dept Pathol & Legal Med, Sao Paulo, Brazil.;Modestum LTD, London, England..
    Traini, Eugenio
    Univ Utrecht, Inst Risk Assessment Sci IRAS, Utrecht, Netherlands..
    Tran, Bach Xuan
    Hanoi Med Univ, Dept Hlth Econ, Hanoi, Vietnam..
    Travillian, Ravensara
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Trias-Llimos, Sergi
    London Sch Hyg & Trop Med, Dept Noncommunicable Dis Epidemiol, London, England..
    Troeger, Christopher E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Truelsen, Thomas Clement
    Univ Copenhagen, Rigshosp, Copenhagen, Denmark..
    Tsai, Alexander C.
    Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA.;Mbarara Univ Sci & Technol, Mbarara, Uganda..
    Tsatsakis, Aristidis
    Univ Crete, Dept Med, Iraklion, Greece..
    Car, Lorainne Tudor
    Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore, Singapore..
    Tyrovolas, Stefanos
    Biomed Res Networking Ctr Mental Hlth Network Cib, Barcelona, Spain.;St John God Hlth Pk, San Juan Dios Sanitary Pk, St Boi De Llobregat, Spain..
    Uddin, Riaz
    Univ Queensland, Sch Hlth & Rehabil Sci, Brisbane, Qld, Australia.;Deakin Univ, Inst Phys Act & Nutr, Burwood, Vic, Australia..
    Ullah, Irfan
    Iqra Natl Univ, Dept Microbiol, Peshawar, Pakistan.;Mufti Mehmood Mem Teaching Hosp, TB Culture Lab, Dera Ismail Khan, Pakistan..
    Ullah, Saif
    Univ Agr Faisalabad, Inst Soil & Environm Sci, Faisalabad, Pakistan..
    Umeokonkwo, Chukwuma David
    Alex Ekwueme Fed Univ Teaching Hosp Abakaliki, Dept Community Med, Abakaliki, Nigeria..
    Undurraga, Eduardo A.
    Pontificia Univ Catolica Chile, Sch Govt, Santiago, Chile.;Brandeis Univ, Schneider Inst Hlth Policy, Waltham, MA USA..
    Unnikrishnan, Bhaskaran
    Manipal Acad Higher Educ, Kasturba Med Coll, Mangalore, India..
    Upadhyay, Era
    Amity Univ Rajasthan, Amity Inst Biotechnol, Jaipur, Rajasthan, India..
    Uthman, Olalekan A.
    Univ Warwick, Div Hlth Sci, Coventry, W Midlands, England..
    Vacante, Marco
    Univ Catania, Dept Gen Surg & Med Surg Specialties, Catania, Italy..
    Vaicekonyte, Regina
    Delos Living, Delos Labs, New York, NY USA..
    Vakilian, Alireza
    Rafsanjan Univ Med Sci, Dept Neurol, Rafsanjan, Iran.;Rafsanjan Univ Med Sci, Noncommunicable Dis Res Ctr, Rafsanjan, Iran..
    Valdez, Pascual R.
    Argentine Soc Med, Board Directos, Buenos Aires, DF, Argentina.;Velez Sarsfield Hosp, Buenos Aires, DF, Argentina..
    Valli, Alessandro
    Univ Catania, Dept Gen Surg & Med Surg Specialties, Catania, Italy..
    Van Donkelaar, Aaron
    Washington Univ, Dept Energy Environm & Chem Engn, St Louis, MO 63110 USA.;Dalhousie Univ, Dept Phys & Atmospher Sci, Halifax, NS, Canada..
    Vardavas, Constantine
    Univ Crete, Toxicol Lab, Iraklion, Greece..
    Varughese, Santosh
    Christian Med Coll & Hosp CMC, Dept Nephrol, Vellore, Tamil Nadu, India..
    Vasankari, Tommi Juhani
    UKK Inst, Tampere, Finland..
    Vasconcelos, Ana Maria Nogales
    Univ Brasilia, Dept Stat, Brasilia, DF, Brazil..
    Vasseghian, Yasser
    Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran..
    Veisani, Yousef
    Ilam Univ Med Sci, Psychosocial Injuries Res Ctr, Ilam, Iran..
    Venketasubramanian, Narayanaswamy
    Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore.;Raffles Hosp, Raffles Neurosci Ctr, Singapore, Singapore..
    Vidale, Simone
    Infermi Hosp, Dept Neurol, Rimini, Italy.;St Anna Hosp, Dept Neurol, Como, Italy.;St Anna Hosp, Stroke Unit, Como, Italy..
    Violante, Francesco S.
    Univ Bologna, Dept Med & Surg Sci, Bologna, Italy.;St Orsola Malpighi Hosp, Occupat Hlth Unit, Bologna, Italy..
    Vlassov, Vasily
    Natl Res Univ Higher Sch Econ, Dept Hlth Care Adm & Econ, Moscow, Russia..
    Vollset, Stein Emil
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Vongpradith, Avina
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Vos, Theo
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Vu, Giang Thu
    Nguyen Tat Thanh Univ, Ctr Excellence Behav Med, Ho Chi Minh City, Vietnam..
    Vujcic, Isidora S.
    Univ Belgrade, Fac Med, Inst Epidemiol, Belgrade, Serbia..
    Vukovic, Ana
    Univ Belgrade, Dept Pediat & Prevent Dent, Belgrade, Serbia..
    Vukovic, Rade
    Univ Belgrade, Sch Med, Belgrade, Serbia.;Mother & Child Healthcare Inst Serbia Dr Vukan Cu, Dept Pediat Endocrinol, Belgrade, Serbia..
    Hawariat, Feleke Gebremeskel W.
    Arba Minch Univ, Dept Publ Hlth, Arba Minch, Ethiopia..
    Waheed, Yasir
    Fdn Univ Islamabad, Fdn Univ Med Coll, Islamabad, Pakistan..
    Wallin, Mitchell Taylor
    Univ Maryland, Sch Med, Baltimore, MD 21201 USA.;George Washington Univ, Dept Neurol, Washington, DC USA..
    Walters, Magdalene K.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wamai, Richard G.
    Univ Nairobi, Sch Publ Hlth, Nairobi, Kenya.;Northeastern Univ, Cultures Soc & Global Studies & Integrated Initia, Boston, MA 02115 USA..
    Wang, Fang
    Wuhan Univ, Sch Hlth Sci, Wuhan, Peoples R China..
    Wang, Haidong
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Hong Kong Univ Sci & Technol, Div Social Sci, Hong Kong, Peoples R China..
    Wang, Hongbo
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wang, Jiayu
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wang, Yafeng
    Univ Sao Paulo, Dept Psychiat, Sao Paulo, Brazil.;Wuhan Univ, Dept Epidemiol & Biostat, Wuhan, Peoples R China..
    Wang, Yanzhong
    Wang, Yuan-Pang
    Ward, Joseph L.
    UCL, Great Ormond St Inst Child Hlth, London, England..
    Watson, Alexandrea
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Watson, Stefanie
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wei, Jingkai
    George Washington Univ, Dept Epidemiol & Biostat, Washington, DC USA..
    Wei, Melissa Y. Wei
    Univ Michigan, Sch Med, Ann Arbor, MI USA..
    Weintraub, Robert G.
    Murdoch Childrens Res Inst, Crit Care & Neurosci Dept, Melbourne, Vic, Australia.;Royal Childrens Hosp, Dept Cardiol, Melbourne, Vic, Australia..
    Weiss, Daniel J.
    Univ Oxford, Malaria Atlas Project, Oxford, England..
    Weiss, Jordan
    Univ Penn, Leonard Davis Inst Hlth Econ, Philadelphia, PA 19104 USA.;Univ Penn, Ctr Populat Studies, Philadelphia, PA 19104 USA..
    Welay, Fissaha Tekulu
    Adigrat Univ, Dept Midwifery, Adigrat, Ethiopia..
    Weldesamuel, Girmay Teklay
    Aksum Univ, Dept Nursing, Aksum, Ethiopia..
    Werdecker, Andrea
    Fed Inst Populat Res, Demog Change & Aging Res Area, Wiesbaden, Germany..
    West, J. Jason
    Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27515 USA..
    Westerman, Ronny
    Fed Inst Populat Res, Competence Ctr Mortal Follow Up German Natl Cohor, Wiesbaden, Germany..
    Whisnant, Joanna L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Whiteford, Harvey A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia..
    Wiangkham, Taweewat
    Naresuan Univ, Dept Phys Therapy, Phitsanulok, Thailand..
    Wickramasinghe, Nuwan Darshana
    Rajarata Univ Sri Lanka, Dept Community Med, Anuradhapura, Sri Lanka..
    Wiens, Kirsten E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wijeratne, Tissa
    Univ Melbourne, Dept Neurol, Melbourne, Vic, Australia.;Univ Rajarata, Dept Med, Saliyapura Anuradhapuray, Sri Lanka..
    Wilner, Lauren B.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wilson, Shadrach
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wiysonge, Charles Shey
    South African Med Res Council, Cape Town, South Africa.;Univ Cape Town, Sch Publ Hlth & Family Med, Cape Town, South Africa..
    Wojtyniak, Bogdan
    Natl Inst Publ Hlth, Dept Populat Hlth Monitoring & Anal, Warsaw, Poland..
    Woldu, Gebremariam
    Aksum Univ, Sch Pharm, Aksum, Ethiopia..
    Wolfe, Charles D. A.
    Kings Coll London, Sch Populat Hlth & Environm Sci, London, England.;Guys & St Thomas Hosp, NIHR Biomed Res Ctr, London, England.;Kings Coll London, London, England..
    Wondmeneh, Temesgen Gebeyehu
    Samara Univ, Dept Publ Hlth, Samara, Ethiopia..
    Wondmieneh, Adam Belay
    Addis Ababa Univ, Sch Nursing & Midwifery, Addis Ababa, Ethiopia.;Wollo Univ, Dept Nursing, Dessie, Ethiopia..
    Wool, Eve E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wozniak, Sarah S.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wu, Ai-Min
    Wenzhou Med Univ, Dept Orthopaed, Wenzhou, Peoples R China..
    Wu, Chenkai
    Duke Univ, Duke Global Hlth Inst, Durham, NC USA..
    Wu, Junjie
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Hanson, Sarah Wulf
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Wunrow, Han Yong
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Xie, Yang
    Beijing Adv Innovat Ctr Big Data Based Precis Med, Dept Behav & Operat Management, Beijing, Peoples R China..
    Xu, Gelin
    Nanjing Univ, Sch Med, Nanjing, Peoples R China..
    Xu, Rixing
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Yadgir, Simon
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Jabbari, Seyed Hossein Yahyazadeh
    Milad Gen Hosp, Clin Canc Res Ctr, Tehran, Iran..
    Yamada, Tomohide
    Univ Tokyo, Dept Diabet & Metab Dis, Tokyo, Japan..
    Yamagishi, Kazumasa
    Osaka Univ, Grad Sch Med, Suita, Osaka, Japan.;Univ Tsukuba, Res & Dev Ctr Hlth Serv, Tsukuba, Ibaraki, Japan..
    Yaminfirooz, Mousa
    Babol Univ Med Sci, Gen Educ Dept, Babol, Iran.;Babol Univ Med Sci, Social Determinants Hlth Res Ctr, Babol, Iran..
    Yano, Yuichiro
    Duke Univ, Dept Family Med & Community Hlth, Durham, NC USA..
    Yaya, Sanni
    Univ Oxford, George Inst Global Hlth, Oxford, England.;Univ Ottawa, Sch Int Dev & Global Studies, Ottawa, ON, Canada..
    Yazdi-Feyzabadi, Vahid
    Kerman Univ Med Sci, Dept Hlth Management Policy & Econ, Kerman, Iran.;Kerman Univ Med Sci, Hlth Serv Management Res Ctr, Kerman, Iran..
    Yearwood, Jamal A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Yeheyis, Tomas Y.
    Hawassa Univ, Sch Nursing, Hawassa, Ethiopia..
    Yeshitila, Yordanos Gizachew
    Arba Minch Univ, Dept Nursing, Arba Minch, Ethiopia..
    Yilgwan, Christopher Sabo
    Univ Jos, Dept Pediat, Jos, Nigeria.;Jos Univ Teaching Hosp, Dept Pediat, Jos, Nigeria..
    Yilma, Mekdes Tigistu
    Wollega Univ, Dept Publ Hlth, Nekemte, Ethiopia..
    Yip, Paul
    Univ Hong Kong, Ctr Suicide Res & Prevent, Hong Kong, Peoples R China.;Univ Hong Kong, Dept Social Work & Social Adm, Hong Kong, Peoples R China..
    Yonemoto, Naohiro
    Natl Ctr Neurol & Psychiat, Dept Neuropsychopharmaol, Kodaira, Tokyo, Japan.;Juntendo Univ, Dept Publ Hlth, Tokyo, Japan..
    Yoon, Seok-Jun
    Korea Univ, Dept Prevent Med, Seoul, South Korea..
    Lebni, Javad Yoosefi
    Iran Univ Med Sci, Dept Hlth Educ & Promot, Tehran, Iran..
    York, Hunter W.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Younis, Mustafa Z.
    Jackson State Univ, Dept Hlth Policy & Management, Jackson, MS USA.;Tsinghua Univ, Sch Med, Beijing, Peoples R China..
    Younker, Theodore Patrick
    Univ Pittsburgh, Dept Immunol, Pittsburgh, PA USA..
    Yousefi, Bahman
    Tabriz Univ Med Sci, Mol Med Res Ctr, Tabriz, Iran..
    Yousefi, Zabihollah
    Mazandaran Univ Med Sci, Dept Environm Hlth, Sari, Iran..
    Yousefifard, Mahmoud
    Iran Univ Med Sci, Physiol Res Ctr, Tehran, Iran..
    Yousefinezhadi, Taraneh
    Shahid Beheshti Univ Med Sci, Injury Prevent & Safety Promot Res Ctr, Tehran, Iran..
    Yousuf, Abdilahi Yousuf
    Jigjiga Univ, Dept Publ Hlth, Jijiga, Ethiopia..
    Yu, Chuanhua
    Wuhan Univ, Dept Epidemiol & Biostat, Wuhan, Peoples R China.;Wuhan Univ, Global Hlth Inst, Wuhan, Peoples R China..
    Yu, Yong
    Hubei Univ Med, Sch Publ Hlth & Management, Shiyan, Peoples R China..
    Yuan, Chun-Wei
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Yuce, Deniz
    Hacettepe Univ, Inst Canc, Ankara, Turkey..
    Yusefzadeh, Hasan
    Urmia Univ Med Sci, Dept Hlth Care Management & Econ, Orumiyeh, Iran..
    Zadey, Siddhesh
    Duke Univ, Duke Global Hlth Inst, Durham, NC USA..
    Moghadam, Telma Zahirian
    Ardabil Univ Med Sci, Social Determinants Hlth Res Ctr, Ardebil, Iran..
    Zaidi, Syed Saoud
    Dow Univ Hlth Sci, Dept Pharmaceut, Karachi, Pakistan..
    Zaki, Leila
    Tarbiat Modares Univ, Dept Parasitol & Entomol, Tehran, Iran..
    Zakzuk, Josefina
    Univ Cartagena, Immunol Res Inst, Cartagena, Colombia..
    Bin Zaman, Sojib
    Monash Univ, Monash Hlth, Sch Clin Sci, Melbourne, Vic, Australia.;Int Ctr Diarrhoeal Dis Res, Maternal & Child Hlth Div, Dhaka, Bangladesh..
    Zamani, Mohammad
    Arak Univ Med Sci, Dept Epidemiol, Arak, Iran.;Babol Univ Med Sci, Student Res Comm, Babol, Iran..
    Zamanian, Maryam
    Zandian, Hamed
    Ardabil Univ Med Sci, Dept Community Med, Ardebil, Iran.;Ardabil Univ Med Sci, Social Determinants Hlth Res Ctr, Ardebil, Iran..
    Zangeneh, Alireza
    Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran..
    Zarafshan, Hadi
    Univ Tehran Med Sci, Psychiat & Psychol Res Ctr, Tehran, Iran..
    Zastrozhin, Mikhail Sergeevich
    Moscow Res & Pract Ctr Addict, Lab Genet & Genom, Moscow, Russia.;Russian Med Acad Continuous Profess Educ, Addictol Dept, Moscow, Russia..
    Zewdie, Kaleab Alemayehu
    Mekelle Univ, Sch Pharm, Mekelle, Ethiopia..
    Zhang, Jianrong
    Univ Melbourne, Dept Gen Practice, Melbourne, Vic, Australia.;Victorian Comprehens Canc Ctr, Melbourne, Vic, Australia..
    Zhang, Yunquan
    Wuhan Univ Sci & Technol, Hubei Prov Key Lab Occupat Hazard Identificat & C, Wuhan, Peoples R China.;Wuhan Univ Sci & Technol, Sch Publ Hlth, Wuhan, Peoples R China..
    Zhang, Zhi-Jiang
    Wuhan Univ, Sch Med, Wuhan, Peoples R China..
    Zhao, Jeff T.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Zhao, Xiu-Ju George
    Wuhan Univ, Sch Hlth Sci, Wuhan, Peoples R China.;Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan, Peoples R China..
    Zhao, Yingxi
    Univ Oxford, Nuffield Dept Med, Oxford, England..
    Zheleva, Bistra
    Childrens HeartLink, Global Strategy & Advocacy Unit, Minneapolis, MN USA..
    Zheng, Peng
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Zhou, Maigeng
    Chinese Ctr Dis Control & Prevent, Natl Ctr Chron & Noncommunicable Dis Control & Pr, Beijing, Peoples R China..
    Zhu, Cong
    Univ Texas Hlth Sci Ctr Houston, Dept Epidemiol Human Genet & Environm Sci, Houston, TX 77030 USA..
    Ziapour, Arash
    Kermanshah Univ Med Sci, Dept Hlth Educ & Hlth Promot, Kermanshah, Iran..
    Zimsen, Stephanie R. M.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Zlavog, Bianca S.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Zodpey, Sanjay
    Publ Hlth Fdn India, Indian Inst Publ Hlth, Gurugram, India..
    Lim, Stephen S.
    Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Murray, Christopher J. L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.;Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.;Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA..
    Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 20192020In: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 396, no 10258, p. 1204-1222Article in journal (Refereed)
    Abstract [en]

    In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990-2010 time period, with the greatest annualised rate of decline occurring in the 0-9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10-24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10-24 years were also in the top ten in the 25-49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50-74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and development investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.

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  • 9.
    Abbafati, Cristiana
    et al.
    Univ Roma La Sapienza, Dept Jurid & Econ Studies, Rome, Italy.
    Larsson, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Chemistry.
    Murray, Christopher J. L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA; Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA; Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA 98195 USA.
    Five insights from the Global Burden of Disease Study 20192020In: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 396, no 10258, p. 1135-1159Article in journal (Other academic)
    Abstract [en]

    The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.

  • 10.
    Abdalla Omer, Hemn
    et al.
    University of Sulaimani.
    Amin, Kawa
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    TGFβ1, SMAD2, CTNNβ1, and Wnt3a gene mutational status and serum concentrations in individuals with non-small cell lung cancer2023In: Cellular and Molecular Biology, ISSN 0145-5680, E-ISSN 1165-158X, Vol. 69, no 11, p. 81-91Article in journal (Refereed)
    Abstract [en]

    The objective of the current investigation was to investigate the diagnostic utility of the serum concentrations and mutational status of TGFβ1, SMAD2, CTNNβ1, and Wnt3a. and the expression levels of human-rela-ted genes in patients with non-small cell lung cancer (NSCLC). The serum concentrations were determined using the ELISA technique, and PCR for genotype variations of TGFβ1, SMAD2, CTNNβ1, and Wnt3a were examined using Sanger sequencing in tissue samples obtained from 93 patients with NSCLC and 84 healthy individuals for blood, and 20 Formalin Fixed Paraffin Embedded (FFPE) from normal samples dissected adja-cent to the tumour. The findings of the current investigation indicate that individuals diagnosed with NSCLC exhibited significant elevation in the serum levels of CEA and CYFRA21-1, as well as TGFβ1, SMAD2, CTNNβ1, and Wnt3a. In total, 325 mutations in four trialled genes (243 mutations in TGFβ1, 24 mutations in SMAD2,47 mutation Wnt3a and 11 mutations in CTNNβ1) were identified in patients with NSCLC. Fur-thermore, all mutations were recorded in adenocarcinoma, not squamous and normal adjacent tumour cells. CYFRA21-1 and CEA are more significant between NSCLC and HC, gender, and NSCLC types (p<0.001). In detail, TGFβ1 exhibited the highest rate of mutations among other genes and three types of genomic mutations. Elevated levels and genetic polymorphisms of TGFβ1, SMAD2, CTNNβ1, and Wnt3a may play crucial func-tions in the pathogenesis and angiogenesis of non-small cell lung cancer (NSCLC). These biomarkers might play a role in future immunologic response and pharmacologically targeted NSCLC therapy.

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  • 11.
    Abdalla Omer, Hemn
    et al.
    Department of Microbiology/Immunology, College of Medicine, University of Suleimani, Sulaymaniyah, Iraq.
    Janson, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Amin, Kawa
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research. Department of Microbiology/Immunology, College of Medicine, University of Suleimani, Sulaymaniyah, Iraq.
    The role of inflammatory and remodelling biomarkers in patients with non-small cell lung cancer2023In: Central European Journal of Immunology, ISSN 1426-3912, E-ISSN 1644-4124, Vol. 48, no 4, p. 1-8Article in journal (Refereed)
    Abstract [en]

    Introduction:

    Biomarkers play a crucial role in evaluating the prognosis, diagnosis, and monitoringof non-small cell lung cancer (NSCLC). The aim of this study was to compare the levels of inflammatoryand remodelling biomarkers among patients with NSCLC and healthy controls (HCs) and to investigatethe correlation between these biomarkers.

    Material and methods:

    Blood samples were taken from 93 NSCLC and 84 HCs. Each sample wasanalysed for the inflammatory biomarkers transforming growth factor β1 (TGF-β1), mothers againstdecapentaplegic homolog 2 (SMAD2) and the remodelling biomarkers Wingless-related integration site(Wnt3a) and β-catenin (CTNN-β1).

    Results:

    The patients with NSCLC had significantly higher levels of all the measured biomarkers.In the NSCLC patients, TGF-β1 correlated significantly with SMAD2 (r = 0.34, p = 0.0008), Wnt3a(r = 0.328, p = 0.0013), and CTNN-β1 levels (r = 0.30, p = 0.004). SMAD2 correlated significantlywith CTNN-β1 (r = 0.546, p = 0.0001) and Wnt3a (r = 0.598, p = 0.0001). CTNN-β1 level also correlated with the level of Wnt3a (r = 0.61, p = 0.0001). No correlation was found between biomarkersand symptom scores.

    Discussion:

    In this study, patients with NSCLC had higher inflammatory and remodelling biomarker levels than HCs. In the NSCLC, there were significant associations between inflammatory andremodelling biomarkers. This indicates that measuring biomarkers could be valuable in the workupof NSCLC patients.

    Conclusions:

    Our investigation showed that inflammatory and remodelling biomarkers might playa role in future immunologic response and pharmacologically targeted NSCLC therapy.

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    Lung Cancer
  • 12.
    Abdeldaim, Guma
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Korsgaard, J.
    Köpenhamns Universitet.
    Olcén, P.
    Örebro Universitet, klinisk mikrobiologi.
    Blomberg, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Virology.
    Strålin, Kristoffer
    Örebro Universitet, klinisk mikrobiologi.
    Is quantitative PCR for the pneumolysin (ply) gene useful for detection of pneumococcal lower respiratory tract infection?2009In: Clinical Microbiology and Infection, ISSN 1198-743X, E-ISSN 1469-0691, Vol. 15, no 6, p. 565-570Article in journal (Refereed)
    Abstract [en]

    The pneumolysin (ply) gene is widely used as a target in PCR assays for Streptococcus pneumoniae in respiratory secretions. However, false-positive results with conventional ply-based PCR have been reported. The aim here was to study the performance of a quantitative ply-based PCR for the identification of pneumococcal lower respiratory tract infection (LRTI). In a prospective study, fibreoptic bronchoscopy was performed in 156 hospitalized adult patients with LRTI and 31 controls who underwent bronchoscopy because of suspicion of malignancy. Among the LRTI patients and controls, the quantitative ply-based PCR applied to bronchoalveolar lavage (BAL) fluid was positive at >/=10(3) genome copies/mL in 61% and 71% of the subjects, at >/=10(5) genome copies/mL in 40% and 58% of the subjects, and at >/=10(7) genome copies/mL in 15% and 3.2% of the subjects, respectively. Using BAL fluid culture, blood culture, and/or a urinary antigen test, S. pneumoniae was identified in 19 LRTI patients. As compared with these diagnostic methods used in combination, quantitative ply-based PCR showed sensitivities and specificities of 89% and 43% at a cut-off of 10(3) genome copies/mL, of 84% and 66% at a cut-off of 10(5) genome copies/mL, and of 53% and 90% at a cut-off of 10(7) genome copies/mL, respectively. In conclusion, a high cut-off with the quantitative ply-based PCR was required to reach acceptable specificity. However, as a high cut-off resulted in low sensitivity, quantitative ply-based PCR does not appear to be clinically useful. Quantitative PCR methods for S. pneumoniae using alternative gene targets should be evaluated.

  • 13.
    Abdeldaim, Guma
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Mölling, Paula
    Holmberg, Hans
    Blomberg, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Virology.
    Olcén, Per
    Strålin, Kristoffer
    Usefulness of real-time PCR for lytA, ply, and Spn9802 on plasma samples for the diagnosis of pneumococcal pneumonia2010In: Clinical Microbiology and Infection, ISSN 1198-743X, E-ISSN 1469-0691, Vol. 16, no 8, p. 1135-1141Article in journal (Refereed)
    Abstract [en]

    In the present study, we evaluated rapid real-time PCR assays for ply, Spn9802, and lytA applied to plasma samples for the detection of Streptococcus pneumoniae in patients with community-acquired pneumonia (CAP). In a prospective study of CAP aetiology, an EDTA plasma sample was collected together with blood culture in 92 adult CAP patients and 91 adult controls. Among the 92 CAP patients, lytA PCR was positive in eight (9%), Spn9802 PCR was positive in 11 (12%) and ply PCR was positive in 19 (21%) cases. Of 91 controls, the ply PCR was positive in eight cases (9%), but no positive cases were noted by Spn9802 or lytA PCRs. Ten CAP patients had pneumococcal bacteraemia. Compared to blood culture, PCR for lytA, Spn9802 and ply had sensitivities of 70% (7/10), 60% (6/10) and 70% (7/10), and specificities of 96% (79/82), 94% (77/82) and 85% (70/82) respectively. With blood culture and/or culture of representative sputum, and/or urinary antigen detection, S. pneumoniae was identified in 31 CAP patients. Compared to these tests in combination, PCR for lytA, Spn9802 and ply showed sensitivities of 26% (8/31), 32% (10/31) and 42% (13/31), and specificities of 100% (61/61), 98% (60/61) and 90% (55/61) respectively. We conclude that Spn9802 and lytA PCRs may be useful for the rapid detection of bacteraemic pneumococcal pneumonia, whereas ply PCR is not specific enough for routine use and blood PCR with small plasma volumes is not useful for the detection of nonbacteraemic pneumococcal pneumonia.

  • 14.
    Abdeldaim, Guma M. K.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    PCR detection of Streptococcus pneumoniae and Haemophilus influenzae in pneumonia patients2009Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    PCR is a rapid, reproducible method for nucleic acid detection. However, this technology displays significant deficiencies when applied in clinical microbiology. This work’s aim was to improve current diagnostics and provide sensitive and quantitative real-time PCRs.

    Paper I describes the development of a sensitive and specific quantitative real-time PCR for the detection of Streptococcus pneumoniae, based on the Spn9802 DNA fragment. Applied to nasopharyngeal aspirates from 166 pneumonia patients, Spn9802 PCR had a sensitivity of 94% and a specificity of 98%.

    In Paper II the performance of a ply gene PCR for identification of pneumococcal lower respiratory tract infection (LRTI) was evaluated on bronchoalveloar lavage fluids. At the detection limit 103 genome copies/mL, 89% sensitivity but only 43% specificity was achieved.

    Paper III shows that S. pneumoniae DNA is detectable in plasma from acutely febrile patients. Sensitivities were low (26-42%) for detection of pneumococcal pneumonia, for bacteraemic pneumococcal pneumonia they were 60-70%.

    Paper IV describes evaluation of four PCR targets for Haemophilus influenzae detection. A real-time PCR based on the P6 gene was developed and applied to 166 CAP patients, using cut-off of 104 genome copies/mL the assay had a sensitivity of 97% and a specificity of 96%.

    In paper V, the two real-time PCRs presented in papers I and IV were combined with a PCR for detection of Neisseriae meningitidis. The analytical sensitivity of this multiplex real-time PCR was not affected by using a mixture of reagents and a combined DNA standard (S. pneumoniae/H. influenzae) in single tubes. Applied to 156 LRTI patients, this PCR had sensitivities over 90% for S. pneumoniae and H. influenzae, and specificities of 89% and 96%, respectively.

    In conclusion, real-time PCR assays are useful for the diagnosis of S. pneumoniae and H. influenzae. They enable detection after antibiotic installation, and quantification increases the etiological specificity of pneumonia.

    List of papers
    1. Toward a quantitative DNA-based definition of pneumococcal pneumonia: a comparison of Streptococcus pneumoniae target genes, with special reference to the Spn9802 fragment
    Open this publication in new window or tab >>Toward a quantitative DNA-based definition of pneumococcal pneumonia: a comparison of Streptococcus pneumoniae target genes, with special reference to the Spn9802 fragment
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    2008 (English)In: Diagnostic microbiology and infectious disease, ISSN 0732-8893, E-ISSN 1879-0070, Vol. 60, no 2, p. 143-150Article in journal (Refereed) Published
    Abstract [en]

    The current shift from phenotypically toward genotypically based microbial diagnosis is not unproblematic. A novel quantitative real-time polymerase chain reaction (PCR) assay based on the Spn9802 DNA fragment was therefore developed for detection of Streptococcus pneumoniae. Out of 44 bacterial species, only S. pneumoniae and Streptococcus pseudopneumoniae were positive in Spn9802 PCR. In an evaluation on nasopharyngeal aspirates from 166 patients with community-acquired pneumonia, the assay was positive in 49 of 50 culture-positive cases. Of 19 culture-negative but Spn9802 PCR-positive cases, 12 were confirmed as S. pneumoniae by rnpB sequence analysis. With an expanded reference standard, including culture and rnpB sequencing, Spn9802 had a sensitivity of 94% and a specificity of 98%. A cutoff for clinically significant positivity was 10(4) DNA copies/mL, giving 71% sensitivity and 100% specificity. In conclusion, Spn9802 real-time PCR is highly sensitive and specific. The quantification it provides enables differentiation between pneumococcal pathogenicity and commensalism.

    Keywords
    S. pneumoniae, Pneumonia, Real-time PCR, Spn9802
    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:uu:diva-11875 (URN)10.1016/j.diagmicrobio.2007.08.010 (DOI)000252915100002 ()17916422 (PubMedID)
    Available from: 2008-12-02 Created: 2008-12-02 Last updated: 2017-12-11Bibliographically approved
    2. Is quantitative PCR for the pneumolysin (ply) gene useful for detection of pneumococcal lower respiratory tract infection?
    Open this publication in new window or tab >>Is quantitative PCR for the pneumolysin (ply) gene useful for detection of pneumococcal lower respiratory tract infection?
    Show others...
    2009 (English)In: Clinical Microbiology and Infection, ISSN 1198-743X, E-ISSN 1469-0691, Vol. 15, no 6, p. 565-570Article in journal (Refereed) Published
    Abstract [en]

    The pneumolysin (ply) gene is widely used as a target in PCR assays for Streptococcus pneumoniae in respiratory secretions. However, false-positive results with conventional ply-based PCR have been reported. The aim here was to study the performance of a quantitative ply-based PCR for the identification of pneumococcal lower respiratory tract infection (LRTI). In a prospective study, fibreoptic bronchoscopy was performed in 156 hospitalized adult patients with LRTI and 31 controls who underwent bronchoscopy because of suspicion of malignancy. Among the LRTI patients and controls, the quantitative ply-based PCR applied to bronchoalveolar lavage (BAL) fluid was positive at >/=10(3) genome copies/mL in 61% and 71% of the subjects, at >/=10(5) genome copies/mL in 40% and 58% of the subjects, and at >/=10(7) genome copies/mL in 15% and 3.2% of the subjects, respectively. Using BAL fluid culture, blood culture, and/or a urinary antigen test, S. pneumoniae was identified in 19 LRTI patients. As compared with these diagnostic methods used in combination, quantitative ply-based PCR showed sensitivities and specificities of 89% and 43% at a cut-off of 10(3) genome copies/mL, of 84% and 66% at a cut-off of 10(5) genome copies/mL, and of 53% and 90% at a cut-off of 10(7) genome copies/mL, respectively. In conclusion, a high cut-off with the quantitative ply-based PCR was required to reach acceptable specificity. However, as a high cut-off resulted in low sensitivity, quantitative ply-based PCR does not appear to be clinically useful. Quantitative PCR methods for S. pneumoniae using alternative gene targets should be evaluated.

    Keywords
    Bronchoalveolar lavage, PCR, pneumolysin, pneumonia, Streptococcus pneumoniae
    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:uu:diva-102538 (URN)10.1111/j.1469-0691.2009.02714.x (DOI)000268261300011 ()19416297 (PubMedID)
    Available from: 2009-05-07 Created: 2009-05-07 Last updated: 2022-01-28Bibliographically approved
    3. Usefulness of real-time PCR for lytA, ply, and Spn9802 on plasma samples for the diagnosis of pneumococcal pneumonia
    Open this publication in new window or tab >>Usefulness of real-time PCR for lytA, ply, and Spn9802 on plasma samples for the diagnosis of pneumococcal pneumonia
    Show others...
    2010 (English)In: Clinical Microbiology and Infection, ISSN 1198-743X, E-ISSN 1469-0691, Vol. 16, no 8, p. 1135-1141Article in journal (Refereed) Published
    Abstract [en]

    In the present study, we evaluated rapid real-time PCR assays for ply, Spn9802, and lytA applied to plasma samples for the detection of Streptococcus pneumoniae in patients with community-acquired pneumonia (CAP). In a prospective study of CAP aetiology, an EDTA plasma sample was collected together with blood culture in 92 adult CAP patients and 91 adult controls. Among the 92 CAP patients, lytA PCR was positive in eight (9%), Spn9802 PCR was positive in 11 (12%) and ply PCR was positive in 19 (21%) cases. Of 91 controls, the ply PCR was positive in eight cases (9%), but no positive cases were noted by Spn9802 or lytA PCRs. Ten CAP patients had pneumococcal bacteraemia. Compared to blood culture, PCR for lytA, Spn9802 and ply had sensitivities of 70% (7/10), 60% (6/10) and 70% (7/10), and specificities of 96% (79/82), 94% (77/82) and 85% (70/82) respectively. With blood culture and/or culture of representative sputum, and/or urinary antigen detection, S. pneumoniae was identified in 31 CAP patients. Compared to these tests in combination, PCR for lytA, Spn9802 and ply showed sensitivities of 26% (8/31), 32% (10/31) and 42% (13/31), and specificities of 100% (61/61), 98% (60/61) and 90% (55/61) respectively. We conclude that Spn9802 and lytA PCRs may be useful for the rapid detection of bacteraemic pneumococcal pneumonia, whereas ply PCR is not specific enough for routine use and blood PCR with small plasma volumes is not useful for the detection of nonbacteraemic pneumococcal pneumonia.

    Keywords
    lytA gene, plasma, ply gene, pneumococcal pneumonia, real-time PCR, Spn9802 fragment, Streptococcus pneumoniae
    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:uu:diva-125332 (URN)10.1111/j.1469-0691.2009.03069.x (DOI)000280359900015 ()19832718 (PubMedID)
    Available from: 2010-05-17 Created: 2010-05-17 Last updated: 2022-01-28Bibliographically approved
    4. Detection of Haemophilus influenzae in respiratory secretions from pneumonia patients by quantitative real-time polymerase chain reaction
    Open this publication in new window or tab >>Detection of Haemophilus influenzae in respiratory secretions from pneumonia patients by quantitative real-time polymerase chain reaction
    Show others...
    2009 (English)In: Diagnostic microbiology and infectious disease, ISSN 0732-8893, E-ISSN 1879-0070, Vol. 64, no 4, p. 366-373Article in journal (Refereed) Published
    Abstract [en]

    A quantitative real-time polymerase chain reaction (PCR) based on the omp P6 gene was developed to detect Haemophilus influenzae. Its specificity was determined by analysis of 29 strains of 11 different Haemophilus spp. and was compared with PCR assays having other target genes: rnpB, 16S rRNA, and bexA. The method was evaluated on nasopharyngeal aspirates from 166 adult patients with community-acquired pneumonia. When 104 DNA copies/mL was used as cutoff limit for the method, P6 PCR had a sensitivity of 97.5% and a specificity of 96.0% compared with the culture. Of 20 culture-negative but P6 PCR-positive cases, 18 were confirmed by fucK PCR as H. influenzae. Five (5.9%) of 84 nasopharyngeal aspirates from adult controls tested PCR positive. We conclude that the P6 real-time PCR is both sensitive and specific for identification of H. influenzae in respiratory secretions. Quantification facilitates discrimination between disease-causing H. influenzae strains and commensal colonization.

    Place, publisher, year, edition, pages
    Elsevier, 2009
    Keywords
    H. influenzae, Pneumonia, Real-time PCR, Outer membrane protein P6, fucK, rnpB
    National Category
    Microbiology in the medical area
    Research subject
    Microbiology
    Identifiers
    urn:nbn:se:uu:diva-106189 (URN)10.1016/j.diagmicrobio.2009.03.030 (DOI)000269337900002 ()19446978 (PubMedID)
    Available from: 2009-06-17 Created: 2009-06-17 Last updated: 2022-01-28Bibliographically approved
    5. Multiplex quantitative PCR for detection of lower respiratory tract infection and meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis
    Open this publication in new window or tab >>Multiplex quantitative PCR for detection of lower respiratory tract infection and meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis
    Show others...
    2010 (English)In: BMC Microbiology, E-ISSN 1471-2180, Vol. 10, p. 310-Article in journal (Refereed) Published
    Abstract [en]

    Background. Streptococcus pneumoniae and Haemophilus influenzae cause pneumonia and as Neisseria meningitidis they are important agents of meningitis. Although several PCR methods have been described for these bacteria the specificity is an underestimated problem. Here we present a quantitative multiplex real-time PCR (qmPCR) for detection of S. pneumoniae (9802 gene fragment), H. influenzae (omp P6 gene) and N. meningitidis (ctrA gene). The method was evaluated on bronchoalveolar lavage (BAL) samples from 156 adults with lower respiratory tract infection (LRTI) and 31 controls, and on 87 cerebrospinal fluid (CSF) samples from meningitis patients.

    Results. The analytical sensitivity was not affected by using a combined mixture of reagents and a combined DNA standard (S. pneumoniae/H. influenzae/N. meningitidis) in single tubes. By blood- and BAL-culture and S. pneumoniae urinary antigen test, S. pneumoniae and H. influenzae were aetiological agents in 21 and 31 of the LTRI patients, respectively. These pathogens were identified by qmPCR in 52 and 72 of the cases, respectively, yielding sensitivities and specificities of 95% and 75% for S. pneumoniae, and 90% and 65% for H. influenzae, respectively. When using a cut-off of 105 genome copies/mL for clinical positivity the sensitivities and specificities were 90% and 80% for S. pneumoniae, and 81% and 85% for H. influenzae, respectively. Of 44 culture negative but qmPCR positive for H. influenzae, 41 were confirmed by fucK PCR as H. influenzae. Of the 103 patients who had taken antibiotics prior to sampling, S. pneumoniae and H. influenzae were identified by culture in 6% and 20% of the cases, respectively, and by the qmPCR in 36% and 53% of the cases, respectively. In 87 CSF samples S. pneumoniae and N. meningitidis were identified by culture and/or 16 S rRNA in 14 and 10 samples and by qmPCR in 14 and 10 samples, respectively, giving a sensitivity of 100% and a specificity of 100% for both bacteria.

    Conclusions. The PCR provides increased sensitivity and the multiplex format facilitates diagnosis of S. pneumoniae, H. influenzae and N. meningitidis and the assay enable detection after antibiotic treatment has been installed. Quantification increases the specificity of the etiology for pneumonia.

    Keywords
    S. pneumoniae, H. influenzae, N. meningitidis, quantitative multiplex PCR, lower respiratory tract infection
    National Category
    Medical and Health Sciences
    Research subject
    Clinical Bacteriology
    Identifiers
    urn:nbn:se:uu:diva-107967 (URN)10.1186/1471-2180-10-310 (DOI)000285888900001 ()21129171 (PubMedID)
    Available from: 2009-09-02 Created: 2009-09-02 Last updated: 2024-01-17Bibliographically approved
    Download full text (pdf)
    FULLTEXT01
  • 15.
    Abdeldaim, Guma M. K.
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Bacteriology.
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Bacteriology.
    PCR detection of haemophilus influenzae from respiratory specimens2013In: PCR Detection of Microbial Pathogens / [ed] Mark Wilks, Humana Press, 2013, 2, p. 115-123Chapter in book (Refereed)
    Abstract [en]

    The detection of Haemophilus influenzae by conventional methods like culture is time-consuming and may give false-negative results, especially during ongoing antibiotic treatment. Therefore, non-culture based methods that are sensitive, specific, and rapid are valuable for early diagnosis and effective therapy. Here we describe a quantitative real-time PCR assay based on the outer membrane P6 gene omp6, to detect H. influenzae and its application on respiratory tract specimens.

  • 16.
    Abdeldaim, Guma M. K.
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Bacteriology.
    Stralin, Kristoffer
    Olcen, Per
    Blomberg, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Virology.
    Molling, Paula
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Bacteriology.
    Quantitative fucK gene polymerase chain reaction on sputum and nasopharyngeal secretions to detect Haemophilus influenzae pneumonia2013In: Diagnostic microbiology and infectious disease, ISSN 0732-8893, E-ISSN 1879-0070, Vol. 76, no 2, p. 141-146Article in journal (Refereed)
    Abstract [en]

    A quantitative polymerase chain reaction (PCR) for the fucK gene was developed for specific detection of Haemophilus influenzae. The method was tested on sputum and nasopharyngeal aspirate (NPA) from 78 patients with community-acquired pneumonia (CAP). With a reference standard of sputum culture and/or serology against the patient's own nasopharyngeal isolate, H. influenzae etiology was detected in 20 patients. Compared with the reference standard, fucK PCR (using the detection limit 10(5) DNA copies/mL) on sputum and NPA showed a sensitivity of 95.0% (19/20) in both cases, and specificities of 87.9% (51/58) and 89.5% (52/58), respectively. In a receiver operating characteristic curve analysis, sputum fucK PCR was found to be significantly superior to sputum P6 PCR for detection of H. influenzae CAP. NPA fucK PCR was positive in 3 of 54 adult controls without respiratory symptoms. In conclusion, quantitative fucK real-time PCR provides a sensitive and specific identification of H. influenzae in respiratory secretions.

  • 17.
    Abdeldaim, Guma M. K.
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Strålin, Kristoffer
    Department of Infectious Diseases, Örebro University Hospital.
    Kirsebom, Leif A.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology, Microbiology.
    Olcén, Per
    Department of Clinical Microbiology, Örebro University Hospital.
    Blomberg, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Virology.
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Detection of Haemophilus influenzae in respiratory secretions from pneumonia patients by quantitative real-time polymerase chain reaction2009In: Diagnostic microbiology and infectious disease, ISSN 0732-8893, E-ISSN 1879-0070, Vol. 64, no 4, p. 366-373Article in journal (Refereed)
    Abstract [en]

    A quantitative real-time polymerase chain reaction (PCR) based on the omp P6 gene was developed to detect Haemophilus influenzae. Its specificity was determined by analysis of 29 strains of 11 different Haemophilus spp. and was compared with PCR assays having other target genes: rnpB, 16S rRNA, and bexA. The method was evaluated on nasopharyngeal aspirates from 166 adult patients with community-acquired pneumonia. When 104 DNA copies/mL was used as cutoff limit for the method, P6 PCR had a sensitivity of 97.5% and a specificity of 96.0% compared with the culture. Of 20 culture-negative but P6 PCR-positive cases, 18 were confirmed by fucK PCR as H. influenzae. Five (5.9%) of 84 nasopharyngeal aspirates from adult controls tested PCR positive. We conclude that the P6 real-time PCR is both sensitive and specific for identification of H. influenzae in respiratory secretions. Quantification facilitates discrimination between disease-causing H. influenzae strains and commensal colonization.

  • 18.
    Abdeldaim, Guma M. K.
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Strålin, Kristoffer
    Olcén, Per
    Blomberg, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Virology.
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Toward a quantitative DNA-based definition of pneumococcal pneumonia: a comparison of Streptococcus pneumoniae target genes, with special reference to the Spn9802 fragment2008In: Diagnostic microbiology and infectious disease, ISSN 0732-8893, E-ISSN 1879-0070, Vol. 60, no 2, p. 143-150Article in journal (Refereed)
    Abstract [en]

    The current shift from phenotypically toward genotypically based microbial diagnosis is not unproblematic. A novel quantitative real-time polymerase chain reaction (PCR) assay based on the Spn9802 DNA fragment was therefore developed for detection of Streptococcus pneumoniae. Out of 44 bacterial species, only S. pneumoniae and Streptococcus pseudopneumoniae were positive in Spn9802 PCR. In an evaluation on nasopharyngeal aspirates from 166 patients with community-acquired pneumonia, the assay was positive in 49 of 50 culture-positive cases. Of 19 culture-negative but Spn9802 PCR-positive cases, 12 were confirmed as S. pneumoniae by rnpB sequence analysis. With an expanded reference standard, including culture and rnpB sequencing, Spn9802 had a sensitivity of 94% and a specificity of 98%. A cutoff for clinically significant positivity was 10(4) DNA copies/mL, giving 71% sensitivity and 100% specificity. In conclusion, Spn9802 real-time PCR is highly sensitive and specific. The quantification it provides enables differentiation between pneumococcal pathogenicity and commensalism.

  • 19.
    Abdeldaim, Guma
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Strålin, Kristoffer
    Department of Infectious Diseases, Örebro University Hospital, Örebro.
    Korsgaard, Jens
    Department of Chest Diseases, Aarhus University Hospital, Aalborg, Denmark.
    Blomberg, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Virology.
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
    Multiplex quantitative PCR for detection of lower respiratory tract infection and meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis2010In: BMC Microbiology, E-ISSN 1471-2180, Vol. 10, p. 310-Article in journal (Refereed)
    Abstract [en]

    Background. Streptococcus pneumoniae and Haemophilus influenzae cause pneumonia and as Neisseria meningitidis they are important agents of meningitis. Although several PCR methods have been described for these bacteria the specificity is an underestimated problem. Here we present a quantitative multiplex real-time PCR (qmPCR) for detection of S. pneumoniae (9802 gene fragment), H. influenzae (omp P6 gene) and N. meningitidis (ctrA gene). The method was evaluated on bronchoalveolar lavage (BAL) samples from 156 adults with lower respiratory tract infection (LRTI) and 31 controls, and on 87 cerebrospinal fluid (CSF) samples from meningitis patients.

    Results. The analytical sensitivity was not affected by using a combined mixture of reagents and a combined DNA standard (S. pneumoniae/H. influenzae/N. meningitidis) in single tubes. By blood- and BAL-culture and S. pneumoniae urinary antigen test, S. pneumoniae and H. influenzae were aetiological agents in 21 and 31 of the LTRI patients, respectively. These pathogens were identified by qmPCR in 52 and 72 of the cases, respectively, yielding sensitivities and specificities of 95% and 75% for S. pneumoniae, and 90% and 65% for H. influenzae, respectively. When using a cut-off of 105 genome copies/mL for clinical positivity the sensitivities and specificities were 90% and 80% for S. pneumoniae, and 81% and 85% for H. influenzae, respectively. Of 44 culture negative but qmPCR positive for H. influenzae, 41 were confirmed by fucK PCR as H. influenzae. Of the 103 patients who had taken antibiotics prior to sampling, S. pneumoniae and H. influenzae were identified by culture in 6% and 20% of the cases, respectively, and by the qmPCR in 36% and 53% of the cases, respectively. In 87 CSF samples S. pneumoniae and N. meningitidis were identified by culture and/or 16 S rRNA in 14 and 10 samples and by qmPCR in 14 and 10 samples, respectively, giving a sensitivity of 100% and a specificity of 100% for both bacteria.

    Conclusions. The PCR provides increased sensitivity and the multiplex format facilitates diagnosis of S. pneumoniae, H. influenzae and N. meningitidis and the assay enable detection after antibiotic treatment has been installed. Quantification increases the specificity of the etiology for pneumonia.

  • 20.
    Abdeldaim, Guma
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Bacteriology. Benghazi Univ, Fac Med, Dept Med Microbiol & Parasitol, Benghazi, Libya..
    Svensson, Erik
    Statens Serum Inst, Int Reference Lab Mycobacteriol, Copenhagen, Denmark..
    Blomberg, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Virology.
    Herrmann, Björn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine, Clinical Bacteriology.
    Duplex detection of the Mycobacterium tuberculosis complex and medically important non-tuberculosis mycobacteria by real-time PCR based on the rnpB gene2016In: Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), ISSN 0903-4641, E-ISSN 1600-0463, Vol. 124, no 11, p. 991-995Article in journal (Refereed)
    Abstract [en]

    A duplex real-time PCR based on the rnpB gene was developed for Mycobacterium spp. The assay was specific for the Mycobacterium tuberculosis complex (MTB) and also detected all 19 tested species of non-tuberculous mycobacteria (NTM). The assay was evaluated on 404 clinical samples: 290 respiratory samples and 114 from tissue and other nonrespiratory body sites. M. tuberculosis was detected by culture in 40 samples and in 30 samples by the assay. The MTB assay showed a sensitivity similar to Roche Cobas Amplicor MTB-PCR (Roche Molecular Systems, Pleasanton, CA, USA). There were only nine samples with non-tuberculous mycobacteria detected by culture. Six of them were detected by the PCR assay.

  • 21.
    Abdelgadir, M
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Elbagir, M
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Eltom, A
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Eltom, M
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Berne, C
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Factors affecting perinatal morbidity and mortality in pregnanciescomplicated by diabetes mellitus in Sudan.2003In: Diabetes Res Clin Pract, Vol. 60, p. 41-Article in journal (Refereed)
  • 22.
    Abdelgadir, M
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Elbagir, M
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Eltom, M
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Berne, C
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Ahren, B
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Reduced leptin concentrations in subjects with type 2 diabetes mellitus in Sudan.2002In: Metabolism, Vol. 51, p. 304-Article in journal (Refereed)
  • 23.
    Abdelgadir, Moawia
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Clinical and Biochemical Features of Adult Diabetes Mellitus in Sudan2006Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The high prevalence of diabetes mellitus among the Sudanese population is linked to obesity, poor glycaemic control and a high rate of complications. This study investigated 1/ Leptin hormone and its correlations with different biochemical characteristics in Sudanese diabetic subjects, 2/ The impact of glycaemic control on pregnancy outcome in pregnancies with diabetes, 3/ The glycaemic response to Sudanese traditional carbohydrate foods, 4/ The influence of glucose self-monitoring on the glycaemic control among this population, 5/ The health related quality of life in Sudanese subjects with diabetes-related lower limb amputation.

    Leptin was significantly lower in diabetic subjects compared with controls of same BMI in both females (P =0.0001) and males (P =0.019). In diabetic subjects, serum leptin correlated positively with the homeostatic assessment (HOMA) of both beta-cell function (P =0.018) and insulin resistance (P =.038). In controls, leptin correlated only with insulin resistance. Pregnancy complications were higher among diabetic compared with control women (P<0.0001) and varied with the type of diabetes. Infants of diabetic mothers had a higher incidence of neonatal complications than those of non-diabetic women (P<0.0001). In six Sudanese traditional carbohydrate meals over all differences in incremental AUCs were significant for both plasma glucose (P = 0.0092) and insulin (P = 0.0001). Millet porridge and wheat pancakes displayed significantly lower post-prandial glucose and insulin responses, whereas maize porridge induced a higher post-prandial glucose and insulin response. In type 2 diabetic subjects SMBG or SMUG was not related to glycaemic control. In type 1 diabetic subjects, SMBG was significantly associated with better glycaemic control, as assessed by HbA1c (P=0.02) and blood glucose at clinic visits (P=<0.0001), similar associations were found for SMUG respectively. Neither glycaemic control nor glucose self-monitoring was associated with education level. Diabetic subjects with LLA had significantly poorer HRQL compared to a reference diabetic group (P=<0.0001). Duration of diabetes and amputation had negative impact on HRQL in subjects with LLA (P=<0.0001) respectively. Diabetic subjects with LLA had decreased sense of coherence and high presence of symptoms. Improving health services at the primary level is important to reduce the complications and burden of disease in the Sudanese population.

    List of papers
    1. leptin concentrations in subjects with type 2 diabetes mellitus in Sudan
    Open this publication in new window or tab >>leptin concentrations in subjects with type 2 diabetes mellitus in Sudan
    Show others...
    2002 In: Metabolism, Vol. 51, no 3, p. 304-6Article in journal (Refereed) Published
    Identifiers
    urn:nbn:se:uu:diva-94368 (URN)
    Available from: 2006-05-04 Created: 2006-05-04Bibliographically approved
    2. Factors affecting perinatal morbidity and mortality in pregnancies complicated by diabetes mellitus in Sudan
    Open this publication in new window or tab >>Factors affecting perinatal morbidity and mortality in pregnancies complicated by diabetes mellitus in Sudan
    Show others...
    2003 In: Diabetes Res Clin Pract, Vol. 60, no 1, p. 41-7Article in journal (Refereed) Published
    Identifiers
    urn:nbn:se:uu:diva-94369 (URN)
    Available from: 2006-05-04 Created: 2006-05-04Bibliographically approved
    3. Glycaemic and insulin responses of six traditional Sudanese carbohydrate-rich meals in subjects with Type 2 diabetes mellitus
    Open this publication in new window or tab >>Glycaemic and insulin responses of six traditional Sudanese carbohydrate-rich meals in subjects with Type 2 diabetes mellitus
    Show others...
    Article in journal (Refereed) Published
    Identifiers
    urn:nbn:se:uu:diva-94370 (URN)
    Available from: 2006-05-04 Created: 2006-05-04Bibliographically approved
    4. The influence of glucose self-monitoring on glycaemic control in patients with diabetes mellitus in Sudan
    Open this publication in new window or tab >>The influence of glucose self-monitoring on glycaemic control in patients with diabetes mellitus in Sudan
    2006 (English)In: Diabetes Research and Clinical Practice, ISSN 0168-8227, E-ISSN 1872-8227, Vol. 74, no 1, p. 90-94Article in journal (Refereed) Published
    Abstract [en]

    Objective: To investigate the influence of self-monitoring of glucose on the glycaemic control in Sudanese diabetic subjects.

    Subjects and methods: A group of 193 consecutive type 2 and type I diabetic subjects (95 men, 98 women) were studied. In 104 subjects with type 2 diabetes fasting blood glucose was measured using a glucose meter and blood was obtained for serum glucose measurement in the laboratory. In the remaining 89 diabetic subjects random blood glucose was measured using the same glucose meter and a whole blood sample was drawn for laboratory assessment of HbA1c. Data on self-monitoring and other clinical and personal characteristics were recorded.

    Results: More than 75% of either type I and type 2 diabetic patients never self-monitored blood or urine glucose. In type 2 diabetic subjects self-monitoring of blood or urine glucose was not related to glycaemic control. In type I diabetic subjects, however, self-monitoring of blood glucose was significantly associated with better glycaemic control, as assessed by HbA1c (P = 0.02) and blood glucose at clinic visits (P < 0.0001), and similar associations were found for urine glucose self-monitoring (P = 0.04 and 0.02) respectively. Neither glycaemic control nor glucose self-monitoring was associated with education level.

    Conclusions: Self-monitoring of blood glucose was not found to be associated to better glycaemic control in Sudanese subjects with type 2 diabetes. In contrast, self-monitoring of both blood and urine glucose was significantly associated with glycaemic control in subjects with type I diabetes. Self-monitoring of urine glucose could be useful where measurement of blood glucose is not available or affordable.

    Keywords
    diabetes mellitus, self-monitoring, Sudan
    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:uu:diva-94371 (URN)10.1016/j.diabres.2006.03.003 (DOI)000240801400013 ()16621118 (PubMedID)
    Available from: 2006-05-04 Created: 2006-05-04 Last updated: 2017-12-14Bibliographically approved
    5. Health related quality of life and sense of coherence in Sudanese diabetic subjects with lower limb amputation
    Open this publication in new window or tab >>Health related quality of life and sense of coherence in Sudanese diabetic subjects with lower limb amputation
    Show others...
    2009 (English)In: Tohoku journal of experimental medicine, ISSN 0040-8727, E-ISSN 1349-3329, Vol. 217, no 1, p. 45-50Article in journal (Refereed) Published
    Abstract [en]

    Quality of life is an important outcome measure in diabetic patients with lower limb amputation (LLA). The aim of this study was to investigate the influence of lower limb amputation on health-related quality of life (HRQOL) in Sudanese diabetic subjects. Additionally the Sense of Coherence scale (SOC-13) and a symptom check list was used in subjects with LLA. A total of 60 (M/F; 40/20) diabetic subjects with LLA and 60 (M/F; 23/37) diabetic reference subjects without LLA, were studied. For both groups HRQOL was measured using The Medical Outcomes Study questionnaire (MOS). Subjects with LLA had significantly poorer HRQOL compared to the reference group in most HRQOL domains (p < 0.0001). Duration of diabetes had the greatest negative impact on HRQOL in both groups, those with LLA (p < 0.0001), and in those without LLA (p < 0.0001), although subjects who were amputated earlier had poorer HRQOL than recently amputated (p < 0.0001). Higher SOC scores were recorded in LLA patients who have greater ratings of positive feelings, family satisfaction and sleep in the HRQOL examination (p < 0.0001). In conclusion, Sudanese diabetic subjects with LLA have a poor quality of life. The triad of diabetes duration, symptoms and amputations, has turned to be important risk factor for poorer HRQOL. Functional and mobility status were suggested to be an important determinant of HRQOL among this population. As the Sudanese population has coherent social relationships, this poor performance of the diabetic subjects will certainly increase the burden on the whole family, in both integrity and economical status. Nevertheless, these deep-rooted social interrelations together with increasing diabetes awareness have substantially improved the family satisfaction among our patients.

    Keywords
    Diabetes mellitus, Lower limb amputation, Quality of life, Sense of coherence, Sudan
    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:uu:diva-94372 (URN)10.1620/tjem.217.45 (DOI)000262897800007 ()19155607 (PubMedID)
    Available from: 2006-05-04 Created: 2006-05-04 Last updated: 2022-01-28Bibliographically approved
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  • 24.
    Abdelgadir, Moawia
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences. Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Abbas, M
    Jarvi, A
    Elbagir, M
    Eltom, M
    Berne, Christian
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences. Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Glycaemic and insulin responses of six traditional Sudanese carbohydrate-rich meals in subjects with Type 2 diabetes mellitus.2005In: Diabet Med, ISSN 0742-3071, Vol. 22, no 2, p. 213-217Article in journal (Refereed)
  • 25.
    Abdelgadir, Moawia
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Abbas, Mazahir
    Järvi, Anette
    Elbagir, Murtada
    Eltom, Mohamed
    Berne, Christian
    Glycaemic and insulin responses of six traditional Sudanese carbohydrate-rich meals in subjects with Type 2 diabetes mellitusArticle in journal (Refereed)
  • 26.
    Abdelgadir, Moawia
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Elbagir, Murtada
    Eltom, Aboud
    Eltom, Mohamed
    Berne, Christian
    Factors affecting perinatal morbidity and mortality in pregnancies complicated by diabetes mellitus in Sudan2003In: Diabetes Res Clin Pract, Vol. 60, no 1, p. 41-7Article in journal (Refereed)
  • 27.
    Abdelgadir, Moawia
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Elbagir, Murtada
    Eltom, Mohamed
    Berne, Christian
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    The influence of glucose self-monitoring on glycaemic control in patients with diabetes mellitus in Sudan2006In: Diabetes Research and Clinical Practice, ISSN 0168-8227, E-ISSN 1872-8227, Vol. 74, no 1, p. 90-94Article in journal (Refereed)
    Abstract [en]

    Objective: To investigate the influence of self-monitoring of glucose on the glycaemic control in Sudanese diabetic subjects.

    Subjects and methods: A group of 193 consecutive type 2 and type I diabetic subjects (95 men, 98 women) were studied. In 104 subjects with type 2 diabetes fasting blood glucose was measured using a glucose meter and blood was obtained for serum glucose measurement in the laboratory. In the remaining 89 diabetic subjects random blood glucose was measured using the same glucose meter and a whole blood sample was drawn for laboratory assessment of HbA1c. Data on self-monitoring and other clinical and personal characteristics were recorded.

    Results: More than 75% of either type I and type 2 diabetic patients never self-monitored blood or urine glucose. In type 2 diabetic subjects self-monitoring of blood or urine glucose was not related to glycaemic control. In type I diabetic subjects, however, self-monitoring of blood glucose was significantly associated with better glycaemic control, as assessed by HbA1c (P = 0.02) and blood glucose at clinic visits (P < 0.0001), and similar associations were found for urine glucose self-monitoring (P = 0.04 and 0.02) respectively. Neither glycaemic control nor glucose self-monitoring was associated with education level.

    Conclusions: Self-monitoring of blood glucose was not found to be associated to better glycaemic control in Sudanese subjects with type 2 diabetes. In contrast, self-monitoring of both blood and urine glucose was significantly associated with glycaemic control in subjects with type I diabetes. Self-monitoring of urine glucose could be useful where measurement of blood glucose is not available or affordable.

  • 28.
    Abdelgadir, Moawia
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Elbagir, Murtada
    Eltom, Mohamed
    Berne, Christian
    Ahren, Bo
    leptin concentrations in subjects with type 2 diabetes mellitus in Sudan2002In: Metabolism, Vol. 51, no 3, p. 304-6Article in journal (Refereed)
  • 29.
    Abdelgadir, Moawia
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Endocrinology, Diabetes and Metabolism.
    Karlsson, Anders F.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Endocrinology, Diabetes and Metabolism.
    Berglund, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Disciplinary Domain of Medicine and Pharmacy, research centers etc., Uppsala Clinical Research Center (UCR).
    Berne, Christian
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Endocrinology, Diabetes and Metabolism.
    Low serum adiponectin concentrations are associated with insulin sensitivity independent of obesity in Sudanese subjects with type 2 diabetes mellitus2013In: Diabetology & Metabolic Syndrome, E-ISSN 1758-5996, Vol. 5, p. 15-Article in journal (Refereed)
    Abstract [en]

    Aims: Prevalence of Type 2 diabetes mellitus among Sudanese population was found to be 3.4% and associated with high rates of complications and obesity. Different adipocytokines are secreted from adipose tissues, among them adiponectin, which was shown to have insulins ensitizing properties and anti-inflammatory, anti-atherogenic effect. The aim of this study was to characterize type 2 diabetes in Sudanese diabetic subjects and controls in respect to hormones influencing or influenced by glucose metabolism. Methods: 104 type 2 diabetic patients (45 men and 59 women), and 75 matched control subjects (34 men and 41 women) were studied. Fasting serum samples were used to measure adiponectin, leptin, insulin, proinsulin, ghrelin and glucose. Body mass index, insulin/proinsulin ratio and (HOMA) insulin resistance and beta cell function were also calculated. Results: Adiponectin serum concentrations were significantly lower in subjects with type 2 diabetes compared with controls subjects (P = 0.002), comparison between males and females did not reach significant levels in both diabetic (P = 0.06) or controls (P = 0.16) groups. In the diabetic group adiponectin correlated positively with serum glucose, negatively with serum proinsulin and HOMA beta cell function (P = 0.03) respectively and serum ghrelin (P = 0.003), but not with BMI, HOMA insulin resistance, insulin or leptin. In controls serum adiponectin correlated negatively with BMI (P = 0.002) but not with other variables. Conclusions: The findings of this study suggest that, adiponectin concentrations independent on BMI as a measure of adiposity, were mostly linked to insulin sensitivity and not to insulin resistance in Sudanese type 2 diabetic subjects, where race specific regulation mechanisms or different type 2 diabetes phenotype suggested being a major contributory factor in clarification the findings of this study.

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    fulltext
  • 30.
    Abdelgadir, Moawia
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Shebeika, Wafaa
    Eltom, Mohamed
    Berne, Christian
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Wikblad, Karin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Health related quality of life and sense of coherence in Sudanese diabetic subjects with lower limb amputation2009In: Tohoku journal of experimental medicine, ISSN 0040-8727, E-ISSN 1349-3329, Vol. 217, no 1, p. 45-50Article in journal (Refereed)
    Abstract [en]

    Quality of life is an important outcome measure in diabetic patients with lower limb amputation (LLA). The aim of this study was to investigate the influence of lower limb amputation on health-related quality of life (HRQOL) in Sudanese diabetic subjects. Additionally the Sense of Coherence scale (SOC-13) and a symptom check list was used in subjects with LLA. A total of 60 (M/F; 40/20) diabetic subjects with LLA and 60 (M/F; 23/37) diabetic reference subjects without LLA, were studied. For both groups HRQOL was measured using The Medical Outcomes Study questionnaire (MOS). Subjects with LLA had significantly poorer HRQOL compared to the reference group in most HRQOL domains (p < 0.0001). Duration of diabetes had the greatest negative impact on HRQOL in both groups, those with LLA (p < 0.0001), and in those without LLA (p < 0.0001), although subjects who were amputated earlier had poorer HRQOL than recently amputated (p < 0.0001). Higher SOC scores were recorded in LLA patients who have greater ratings of positive feelings, family satisfaction and sleep in the HRQOL examination (p < 0.0001). In conclusion, Sudanese diabetic subjects with LLA have a poor quality of life. The triad of diabetes duration, symptoms and amputations, has turned to be important risk factor for poorer HRQOL. Functional and mobility status were suggested to be an important determinant of HRQOL among this population. As the Sudanese population has coherent social relationships, this poor performance of the diabetic subjects will certainly increase the burden on the whole family, in both integrity and economical status. Nevertheless, these deep-rooted social interrelations together with increasing diabetes awareness have substantially improved the family satisfaction among our patients.

  • 31. Abdelhak, Ahmed
    et al.
    Barba, Lorenzo
    Romoli, Michele
    Benkert, Pascal
    Conversi, Francesco
    D'Anna, Lucio
    Masvekar, Ruturaj R
    Bielekova, Bibiana
    Prudencio, Mercedes
    Petrucelli, Leonard
    Meschia, James F
    Erben, Young
    Furlan, Roberto
    De Lorenzo, Rebecca
    Mandelli, Alessandra
    Sutter, Raoul
    Hert, Lisa
    Epple, Varenka
    Marastoni, Damiano
    Sellner, Johann
    Steinacker, Petra
    Aamodt, Anne Hege
    Heggelund, Lars
    Dyrhol-Riise, Anne Margarita
    Virhammar, Johan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Neurology.
    Fällmar, David
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Radiology.
    Rostami, Elham
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Neurosurgery. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Acquired brain injury.
    Kumlien, Eva
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Neurology.
    Blennow, Kaj
    Zetterberg, Henrik
    Tumani, Hayrettin
    Sacco, Simona
    Green, Ari J
    Otto, Markus
    Kuhle, Jens
    Ornello, Raffaele
    Foschi, Matteo
    Abu-Rumeileh, Samir
    Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis.2023In: Journal of Neurology, ISSN 0340-5354, E-ISSN 1432-1459, Vol. 270, no 7, p. 3315-3328Article in journal (Refereed)
    Abstract [en]

    BACKGROUND AND AIMS: To investigate the prognostic value of blood neurofilament light chain protein (NfL) levels in the acute phase of coronavirus disease 2019 (COVID-19).

    METHODS: We conducted an individual participant data (IPD) meta-analysis after screening on MEDLINE and Scopus to May 23rd 2022. We included studies with hospitalized adult COVID-19 patients without major COVID-19-associated central nervous system (CNS) manifestations and with a measurement of blood NfL in the acute phase as well as data regarding at least one clinical outcome including intensive care unit (ICU) admission, need of mechanical ventilation (MV) and death. We derived the age-adjusted measures NfL Z scores and conducted mixed-effects modelling to test associations between NfL Z scores and other variables, encompassing clinical outcomes. Summary receiver operating characteristic curves (SROCs) were used to calculate the area under the curve (AUC) for blood NfL.

    RESULTS: We identified 382 records, of which 7 studies were included with a total of 669 hospitalized COVID-19 cases (mean age 66.2 ± 15.0 years, 68.1% males). Median NfL Z score at admission was elevated compared to the age-corrected reference population (2.37, IQR: 1.13-3.06, referring to 99th percentile in healthy controls). NfL Z scores were significantly associated with disease duration and severity. Higher NfL Z scores were associated with a higher likelihood of ICU admission, need of MV, and death. SROCs revealed AUCs of 0.74, 0.80 and 0.71 for mortality, need of MV and ICU admission, respectively.

    CONCLUSIONS: Blood NfL levels were elevated in the acute phase of COVID-19 patients without major CNS manifestations and associated with clinical severity and poor outcome. The marker might ameliorate the performance of prognostic multivariable algorithms in COVID-19.

  • 32.
    Abdsaleh, Shahin
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
    Astrom, Gunnar
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
    Brenning, Gunilla
    Department of Medical Sciences.
    Ahlstrom, Håkan
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
    MR Imaging in Diagnosis of Primary Lymphedema.1996In: 1996 Scientific Program RSNA, p. 419-Article, book review (Other scientific)
  • 33.
    Abdul Qadhr, Göran
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Radiology.
    Molin, Daniel
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Oncology.
    Åström, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Radiology. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Oncology.
    Suurküla, Madis
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Johansson, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Radiology.
    Hagberg, Hans
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Oncology.
    Ahlström, Håkan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Radiology.
    Whole-body diffusion-weighted imaging compared with FDG-PET/CT in staging of lymphoma patients2011In: Acta Radiologica, ISSN 0284-1851, E-ISSN 1600-0455, Vol. 52, no 2, p. 173-180Article in journal (Refereed)
    Abstract [en]

    Background:

    Diffusion-weighted imaging (DWI) has become increasingly valuable in lymph node imaging, yet the clinical utility of this technique in the staging of lymphoma has not been established.

    Purpose:

    To compare whole-body DWI with FDG-PET/CT in the staging of lymphoma patients.

    Material and Methods:

    Thirty-one patients, eight with Hodgkin lymphoma (HL) and 23 with non-Hodgkin's lymphoma (18 aggressive and five indolent) underwent both whole-body DWI, whole-body MRI (T1W and T2W-STIR) and FDG-PET/CT. Lesions on whole-body DWI were only considered positive if they correlated with lesions on T1W and T2W-STIR images. The staging given by each technique was compared, according to the Ann Arbor staging system. Differences in staging were solved using biopsy results, and clinical and CT follow-ups as standard of reference.

    Results:

    The staging was the same for DWI and FDG-PET/CT in 28 (90.3%) patients and different in three (9.7%). Of the 28 patients with the same staging, 11 had stage IV in both techniques and 17 had stages 0-III. No HL or aggressive non-Hodgkin's lymphoma patients had different staging. Three indolent small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) lymphoma had higher staging with DWI when compared with FDG-PET/CT. One small subcutaneous breast lymphoma was not seen but all other extranodal sites were detected by both techniques.

    Conclusion:

    Whole-body DWI is a promising technique for staging of both (aggressive and indolent) non-Hodgkin's lymphoma and HL.

  • 34. Abedini, Sadollah
    et al.
    Holme, Ingar
    Fellström, Bengt
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Jardine, Alan
    Cole, Ed
    Maes, Bart
    Holdaas, Hallvard
    Cerebrovascular events in renal transplant recipients2009In: Transplantation, ISSN 0041-1337, E-ISSN 1534-6080, Vol. 87, no 1, p. 112-7Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: The incidence of stroke and risk factors for different subtypes of cerebrovascular (CBV) events in renal transplant recipients have not been examined in any large prospective controlled trial. METHODS: The Assessment of Lescol in Renal Transplantation was a randomized, double-blind, placebo-controlled study of the effect of fluvastatin (40-80 mg) daily on cardiovascular, and renal outcomes in renal transplant recipients. Patients initially randomized to fluvastatin or placebo in the 5 to 6 year trial was offered open-label fluvastatin in a 2-year extension to the original study. We investigated the incidence of stroke and risk factors for ischemic and hemorrhagic CBV events in 2102 renal graft recipients participating in the Assessment of Lescol in Renal Transplantation core and extension trial with a mean follow-up of 6.7 years. RESULTS: The incidence and type of CBV events did not differ between the lipid lowering arm and the placebo arm. A total of 184 (8.8%, 95% confidence interval 4.6-12.9) of 2102 patients experienced a CBV event during follow-up, corresponding to an incidence of 1.3% CBV event per year. The mortality for patients experiencing a hemorrhagic stroke was 48% (13 of 27), whereas the mortality for ischemic strokes was 6.0% (8 of 133). Diabetes mellitus, previous CBV event, age, and serum creatinine were independent risk factors for cerebral ischemic events. The risk of a hemorrhagic cerebral event was increased by diabetes mellitus, polycystic kidney disease, left ventricular hypertrophy, and systolic blood pressure. INTERPRETATION: Risk factors for CBV events in renal transplant recipients differ according to subtype.

  • 35. Abedini, Sadollah
    et al.
    Holme, Ingar
    März, Winfried
    Weihrauch, Gisela
    Fellström, Bengt
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Jardine, Alan
    Cole, Edward
    Maes, Bart
    Neumayer, Hans-Hellmut
    Grönhagen-Riska, Carola
    Ambühl, Patrice
    Holdaas, Halvard
    Inflammation in renal transplantation2009In: Journal of the American Society of Nephrology, ISSN 1046-6673, E-ISSN 1533-3450, Vol. 4, no 7, p. 1246-1254Article in journal (Refereed)
    Abstract [en]

    BACKGROUND AND OBJECTIVES: Renal transplant recipients experience premature cardiovascular disease and death. The association of inflammation, all-cause mortality, and cardiovascular events in renal transplant recipients has not been examined in a large prospective controlled trial. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: ALERT was a randomized, double-blind, placebo-controlled study of the effect of fluvastatin on cardiovascular and renal outcomes in 2102 renal transplant recipients. Patients initially randomized to fluvastatin or placebo in the 5- to 6-yr trial were offered open-label fluvastatin in a 2-yr extension to the original study. The association between inflammation markers, high-sensitivity C-reactive protein (hsCRP), and IL-6 on cardiovascular events and all-cause mortality was investigated. RESULTS: The baseline IL-6 value was 2.9 +/- 1.9 pg/ml (n = 1751) and that of hsCRP was 3.8 +/- 6.7 mg/L (n = 1910). After adjustment for baseline values for established risk factors, the hazard ratios for a major cardiac event and all-cause mortality for IL-6 were 1.08 [95% confidence interval (CI), 1.01 to 1.15, P = 0.018] and 1.11 (95% CI, 1.05 to 1.18, P < 0.001), respectively. The adjusted hazard ratio for hsCRP for a cardiovascular event was 1.10 (95% CI, 1.01 to 1.20, P = 0.027) and for all-cause mortality was 1.15 (95% CI, 1.06 to 1.1.25, P = 0.049). CONCLUSIONS: The inflammation markers IL-6 and hsCRP are independently associated with major cardiovascular events and all-cause mortality in renal transplant recipients.

  • 36. Abedini, Sadollah
    et al.
    Meinitzer, Andreas
    Holme, Ingar
    März, Winfried
    Weihrauch, Gisela
    Fellström, Bengt
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Jardine, Alan
    Holdaas, Halvard
    Asymmetrical dimethylarginine is associated with renal and cardiovascular outcomes and all-cause mortality in renal transplant recipients2010In: Kidney International, ISSN 0085-2538, E-ISSN 1523-1755, Vol. 77, no 1, p. 44-50Article in journal (Refereed)
    Abstract [en]

    Increased plasma levels of asymmetric dimethylarginine (ADMA) are associated with endothelial dysfunction and predict the progression to dialysis and death in patients with chronic kidney disease. The effects of these increased ADMA levels in renal transplant recipients, however, are unknown. We used the data from ALERT, a randomized, double-blind, placebo-controlled study of the effect of fluvastatin on cardiovascular and renal outcomes in 2102 renal transplant recipients with stable graft function on enrollment. Patients who were initially randomized to fluvastatin or placebo in the 5- to 6-year trial were offered open-label fluvastatin in a 2-year extension of the original study. After adjustment for baseline values for established factors in this post hoc analysis, ADMA was found to be a significant risk factor for graft failure or doubling of serum creatinine (hazard ratio 2.78), major cardiac events (hazard ratio 2.61), cerebrovascular events (hazard ratio 6.63), and all-cause mortality (hazard ratio 4.87). In this trial extension, the number of end points increased with increasing quartiles of plasma ADMA levels. All end points were significantly increased in the fourth compared to the first quartile. Our study shows that elevated plasma levels of ADMA are associated with increased morbidity, mortality, and the deterioration of graft function in renal transplant recipients.

  • 37. Abelsson, J
    et al.
    Merup, M
    Birgegård, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Haematology.
    WeisBjerrum, O
    Brinch, L
    Brune, M
    Johansson, P
    Kauppila, M
    Lenhoff, S
    Liljeholm, M
    Malm, C
    Remes, K
    Vindelöv, L
    Andréasson, B
    The outcome of allo-HSCT for 92 patients with myelofibrosis in the Nordic countries2012In: Bone Marrow Transplantation, ISSN 0268-3369, E-ISSN 1476-5365, Vol. 47, no 3, p. 380-386Article in journal (Refereed)
    Abstract [en]

    Between 1982 and 2009 a total of 92 patients with myelofibrosis (MF) in chronic phase underwent allo-SCT in nine Nordic transplant centers. Myeloablative conditioning (MAC) was given to 40 patients, and reduced intensity conditioning (RIC) was used in 52 patients. The mean age in the two groups at transplantation was 46±12 and 55±8 years, respectively (P<0.001). When adjustment for age differences was made, the survival of the patients treated with RIC was significantly better (P=0.003). Among the RIC patients, the survival was significantly (P=0.003) better for the patients with age <60 years (a 10-year survival close to 80%) than for the older patients. The type of stem cell donor did not significantly affect the survival. No significant difference was found in TRM at 100 days between the MAC- and the RIC-treated patients. The probability of survival at 5 years was 49% for the MAC-treated patients and 59% in the RIC group (P=0.125). Patients treated with RIC experienced significantly less aGVHD compared with patients treated with MAC (P<0.001). The OS at 5 years was 70, 59 and 41% for patients with Lille score 0, 1 and 2, respectively (P=0.038, when age adjustment was made). Twenty-one percent of the patients in the RIC group were given donor lymphocyte infusion because of incomplete donor chimerism, compared with none of the MAC-treated patients (P<0.002). Nine percent of the patients needed a second transplant because of graft failure, progressive disease or transformation to AML, with no significant difference between the groups. Our conclusions are (1) allo-SCT performed with RIC gives a better survival compared with MAC. (2) age over 60 years is strongly related to a worse outcome and (3) patients with higher Lille score had a shorter survival.

  • 38. Abelsson, Johanna
    et al.
    Andreasson, Bjorn
    Samuelsson, Jan
    Hultcrantz, Malin
    Ejerblad, Elisabeth
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Haematology.
    Johansson, Berit
    Emanuel, Robyn
    Mesa, Ruben
    Johansson, Peter
    Patients with polycythemia vera have worst impairment of quality of life among patients with newly diagnosed myeloproliferative neoplasms2013In: Leukemia and Lymphoma, ISSN 1042-8194, E-ISSN 1029-2403, Vol. 54, no 10, p. 2226-2230Article in journal (Refereed)
    Abstract [en]

    The quality of life (QoL) at the time of diagnosis of myeloproliferative neoplasm (MPN) has, to date, not been studied. One hundred and seventy-nine patients with MPN: 80 with essential thrombocythemia (ET), 73 with polycythemia vera (PV), 22 with primary myelofibrosis (PMF) and four with MPN undifferentiated, were included in this study. European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC-QLQC30) and the MPN-Symptom Assessment Form (MPN-SAF) were used to evaluate QoL. Fatigue was the most reported symptom in these patients. Patients with PV reported significantly higher mean scores for inactivity, dizziness, cough, itching, depression and lower total QoL compared to patients with ET. Patients with PV had significantly more headache and itching compared to patients with PMF. When the newly diagnosed patients with MPN were compared with a cohort of patients with MPN with mean disease duration of 7.8 years, the differences were most striking for patients with PMF, with significantly more fatigue, abdominal discomfort, concentration problems, insomnia, fever, weight loss and lower overall QoL developed over time.

  • 39. Aberg, H
    et al.
    Morlin, C
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Lithell, Hans
    Department of Public Health and Caring Sciences.
    Different long-term metabolic effects of enalapril and atenolol in patients with mild hypertension. EGTA Group1995In: J Hum Hypertens, Vol. 9, p. 149-Article in journal (Refereed)
  • 40.
    Aberg, Mikael
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Coagulation and inflammation science.
    Eriksson, Oskar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Coagulation and inflammation science.
    Siegbahn, Agneta
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Coagulation and inflammation science.
    Tissue Factor Noncoagulant Signaling: Mechanisms and Implications for Cell Migration and Apoptosis2015In: Seminars in Thrombosis and Hemostasis, ISSN 0094-6176, E-ISSN 1098-9064, Vol. 41, no 7, p. 691-699Article in journal (Refereed)
    Abstract [en]

    Tissue factor (TF) is a 47-kDa transmembrane glycoprotein and the main initiator of the blood coagulation cascade. Binding to its ligand factor VIIa (FVIIa) also initiates noncoagulant signaling with broad biological implications. In this review, we discuss how TF interacts with other cell-surface proteins, which affect biological functions such as cell migration and cell survival. A vast number of publications have demonstrated the importance of TF-induced activation of protease-activated receptors, but recently published research has indicated a more complicated picture. As it has been discovered that TF interacts with integrins and receptor tyrosine kinases, novel signaling mechanisms for the TF/FVIIa complex have been presented. The knowledge of these new aspects of TF signaling may, for instance, facilitate the development of new treatment strategies for cancer and acute coronary syndromes, two examples of diseases characterized by aberrant TF expression and signaling.

  • 41.
    Ablikim, M.
    et al.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Achasov, M. N.
    GI Budker Inst Nucl Phys SB RAS BINP, Novosibirsk 630090, Russia..
    Ahmed, S.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Ai, X. C.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Albayrak, O.
    Carnegie Mellon Univ, Pittsburgh, PA 15213 USA..
    Albrecht, M.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Ambrose, D. J.
    Univ Rochester, Rochester, NY 14627 USA..
    Amoroso, A.
    GI Budker Inst Nucl Phys SB RAS BINP, Novosibirsk 630090, Russia.;Helmholtz Inst Mainz, D-55099 Mainz, Germany.;Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany.;Chinese Acad Sci, Beijing 100049, Peoples R China.;Univ Hawaii, Honolulu, HI 96822 USA.;Univ Punjab, Lahore 54590, Pakistan.;Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    An, F. F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    An, Q.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Bai, J. Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ferroli, R. Baldini
    INFN Lab Nazl Frascati, I-00044 I- Frascati, Italy..
    Ban, Y.
    Peking Univ, Beijing 100871, Peoples R China..
    Bennett, D. W.
    Indiana Univ, Bloomington, IN 47405 USA..
    Bennett, J. V.
    Carnegie Mellon Univ, Pittsburgh, PA 15213 USA..
    Berger, N. B.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Bertani, M.
    INFN Lab Nazl Frascati, I-00044 I- Frascati, Italy..
    Bettoni, D.
    INFN, Sez Ferrara, I-44122 Ferrara, Italy..
    Bian, J. M.
    Univ Minnesota, Minneapolis, MN 55455 USA..
    Bianchi, F.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Boger, E.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Boyko, I.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Briere, R. A.
    Carnegie Mellon Univ, Pittsburgh, PA 15213 USA..
    Cai, H.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Cai, X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Cakir, O.
    Ankara Univ, TR-06100 Ankara, Turkey..
    Calcaterra, A.
    INFN Lab Nazl Frascati, I-00044 I- Frascati, Italy.;Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany.;Chinese Acad Sci, Beijing 100049, Peoples R China.;Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Cao, G. F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Cetin, S. A.
    Istanbul Bilgi Univ, TR-34060 Istanbul, Turkey..
    Chang, J. F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Chelkov, G.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Chen, G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Chen, H. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Chen, H. Y.
    Beihang Univ, Beijing 100191, Peoples R China..
    Chen, J. C.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Chen, M. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Chen, S.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Chen, S. J.
    Nanjing Univ, Nanjing 210093, Peoples R China..
    Chen, X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Chen, X. R.
    Lanzhou Univ, Lanzhou 730000, Peoples R China..
    Chen, Y. B.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Cheng, H. P.
    Huangshan Coll, Huangshan 245000, Peoples R China..
    Chu, X. K.
    Peking Univ, Beijing 100871, Peoples R China..
    Cibinetto, G.
    INFN, Sez Ferrara, I-44122 Ferrara, Italy..
    Dai, H. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Dai, J. P.
    Shanghai Jiao Tong Univ, Shanghai 200240, Peoples R China..
    Dbeyssi, A.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Dedovich, D.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Deng, Z. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Denig, A.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Denysenko, I.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Destefanis, M.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    De Mori, F.
    Liaoning Univ, Shenyang 110036, Peoples R China..
    Ding, Y.
    Liaoning Univ, Shenyang 110036, Peoples R China..
    Dong, C.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Dong, J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Dong, L. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Dong, M. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Dou, Z. L.
    Nanjing Univ, Nanjing 210093, Peoples R China..
    Du, S. X.
    Zhengzhou Univ, Zhengzhou 450001, Peoples R China..
    Duan, P. F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Fan, J. Z.
    Tsinghua Univ, Beijing 100084, Peoples R China..
    Fang, J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Fang, S. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Fang, X.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Fang, Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Farinelli, R.
    INFN, Sez Ferrara, I-44122 Ferrara, Italy.;Univ Ferrara, I-44122 Ferrara, Italy..
    Fava, L.
    Univ Piemonte Orientale, I-15121 Alessandria, Italy.;INFN, I-10125 Turin, Italy..
    Fedorov, O.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Feldbauer, F.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Felici, G.
    INFN Lab Nazl Frascati, I-00044 I- Frascati, Italy..
    Feng, C. Q.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Fioravanti, E.
    INFN, Sez Ferrara, I-44122 Ferrara, Italy..
    Fritsch, M.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany.;Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Fu, C. D.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Gao, Q.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Gao, X. L.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Gao, X. Y.
    Beihang Univ, Beijing 100191, Peoples R China..
    Gao, Y.
    Tsinghua Univ, Beijing 100084, Peoples R China..
    Gao, Z.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Garzia, I.
    INFN, Sez Ferrara, I-44122 Ferrara, Italy..
    Goetzen, K.
    GSI Helmholtzcentre Heavy Ion Res GmbH, D-64291 Darmstadt, Germany..
    Gong, L.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Gong, W. X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Gradl, W.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Greco, M.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Gu, M. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Gu, Y. T.
    Guangxi Univ, Nanning 530004, Peoples R China..
    Guan, Y. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Guo, A. Q.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Guo, L. B.
    Nanjing Normal Univ, Nanjing 210023, Peoples R China..
    Guo, R. P.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Guo, Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Guo, Y. P.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Haddadi, Z.
    Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands..
    Hafner, A.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Han, S.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Hao, X. Q.
    Henan Normal Univ, Xinxiang 453007, Peoples R China..
    Harris, F. A.
    Univ Hawaii, Honolulu, HI 96822 USA..
    He, K. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Heinsius, F. H.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Held, T.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Heng, Y. K.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Holtmann, T.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Hou, Z. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Hu, C.
    Nanjing Normal Univ, Nanjing 210023, Peoples R China..
    Hu, H. M.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Hu, J. F.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Hu, T.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Hu, Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Huang, G. S.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Huang, J. S.
    Henan Normal Univ, Xinxiang 453007, Peoples R China..
    Huang, X. T.
    Shandong Univ, Jinan 250100, Peoples R China..
    Huang, X. Z.
    Nanjing Univ, Nanjing 210093, Peoples R China..
    Huang, Y.
    Nanjing Univ, Nanjing 210093, Peoples R China..
    Huang, Z. L.
    Liaoning Univ, Shenyang 110036, Peoples R China..
    Hussain, T.
    Univ Punjab, Lahore 54590, Pakistan..
    Ji, Q.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ji, Q. P.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Ji, X. B.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ji, X. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Jiang, L. W.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Jiang, X. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Jiang, X. Y.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Jiao, J. B.
    Shandong Univ, Jinan 250100, Peoples R China..
    Jiao, Z.
    Huangshan Coll, Huangshan 245000, Peoples R China..
    Jin, D. P.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Jin, S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Johansson, Tord
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Julin, A.
    Univ Minnesota, Minneapolis, MN 55455 USA..
    Kalantar-Nayestanaki, N.
    Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands..
    Kang, X. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Kang, X. S.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Kavatsyuk, M.
    Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands..
    Ke, B. C.
    Carnegie Mellon Univ, Pittsburgh, PA 15213 USA..
    Kiese, P.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Kliemt, R.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Kloss, B.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Kolcu, O. B.
    Istanbul Bilgi Univ, TR-34060 Istanbul, Turkey..
    Kopf, B.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Kornicer, M.
    Univ Hawaii, Honolulu, HI 96822 USA..
    Kupsc, Andrzej
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, The Svedberg Laboratory. Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Khn, W.
    Justus Liebig Univ Giessen, Phys Inst 2, D-35392 Giessen, Germany..
    Lange, J. S.
    Justus Liebig Univ Giessen, Phys Inst 2, D-35392 Giessen, Germany..
    Lara, M.
    Indiana Univ, Bloomington, IN 47405 USA..
    Larin, P.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Leithoff, H.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Leng, C.
    INFN, I-10125 Turin, Italy..
    Li, Cui
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Li, Cheng
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Li, D. M.
    Zhengzhou Univ, Zhengzhou 450001, Peoples R China..
    Li, F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, F. Y.
    Peking Univ, Beijing 100871, Peoples R China..
    Li, G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, H. B.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, H. J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, J. C.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, Jin
    Seoul Natl Univ, Seoul 151747, South Korea..
    Li, K.
    Hangzhou Normal Univ, Hangzhou 310036, Peoples R China.;Shandong Univ, Jinan 250100, Peoples R China..
    Li, Lei
    Beijing Inst Petrochem Technol, Beijing 102617, Peoples R China..
    Li, P. R.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Li, Q. Y.
    Shandong Univ, Jinan 250100, Peoples R China..
    Li, T.
    Shandong Univ, Jinan 250100, Peoples R China..
    Li, W. D.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, W. G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, X. L.
    Shandong Univ, Jinan 250100, Peoples R China..
    Li, X. M.
    Guangxi Univ, Nanning 530004, Peoples R China..
    Li, X. N.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Li, X. Q.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Li, Y. B.
    Beihang Univ, Beijing 100191, Peoples R China..
    Li, Z. B.
    Sun Yat Sen Univ, Guangzhou 510275, Guangdong, Peoples R China..
    Liang, H.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Liang, J. J.
    Guangxi Univ, Nanning 530004, Peoples R China..
    Liang, Y. F.
    Sichuan Univ, Chengdu 610064, Peoples R China..
    Liang, Y. T.
    Justus Liebig Univ Giessen, Phys Inst 2, D-35392 Giessen, Germany..
    Liao, G. R.
    Guangxi Normal Univ, Guilin 541004, Peoples R China..
    Lin, D. X.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Liu, B.
    Shanghai Jiao Tong Univ, Shanghai 200240, Peoples R China..
    Liu, B. J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, C. X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, D.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Liu, F. H.
    Shanxi Univ, Taiyuan 030006, Peoples R China..
    Liu, Fang
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, Feng
    Cent China Normal Univ, Wuhan 430079, Peoples R China..
    Liu, H. B.
    Guangxi Univ, Nanning 530004, Peoples R China..
    Liu, H. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China.;Henan Univ Sci & Technol, Luoyang 471003, Peoples R China..
    Liu, H. M.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, J. B.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Liu, J. P.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Liu, J. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, K.
    Tsinghua Univ, Beijing 100084, Peoples R China..
    Liu, K. Y.
    Liaoning Univ, Shenyang 110036, Peoples R China..
    Liu, L. D.
    Peking Univ, Beijing 100871, Peoples R China..
    Liu, P. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, Q.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Liu, S. B.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Liu, X.
    Lanzhou Univ, Lanzhou 730000, Peoples R China..
    Liu, Y. B.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Liu, Y. Y.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Liu, Z. A.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Liu, Zhiqing
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Loehner, H.
    Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands..
    Lou, X. C.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Lu, H. J.
    Huangshan Coll, Huangshan 245000, Peoples R China..
    Lu, J. G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Lu, Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Lu, Y. P.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Luo, C. L.
    Nanjing Normal Univ, Nanjing 210023, Peoples R China..
    Luo, M. X.
    Zhejiang Univ, Hangzhou 310027, Zhejiang, Peoples R China..
    Luo, T.
    Univ Hawaii, Honolulu, HI 96822 USA..
    Luo, X. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Lyu, X. R.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Ma, F. C.
    Liaoning Univ, Shenyang 110036, Peoples R China..
    Ma, H. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ma, L. L.
    Shandong Univ, Jinan 250100, Peoples R China..
    Ma, M. M.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ma, Q. M.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ma, T.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ma, X. N.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Ma, X. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ma, Y. M.
    Shandong Univ, Jinan 250100, Peoples R China..
    Maas, F. E.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Maggiora, M.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Malik, Q. A.
    Univ Punjab, Lahore 54590, Pakistan..
    Mao, Y. J.
    Peking Univ, Beijing 100871, Peoples R China..
    Mao, Z. P.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Marcello, S.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Messchendorp, J. G.
    Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands..
    Mezzadri, G.
    Univ Ferrara, I-44122 Ferrara, Italy..
    Min, J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Mitchell, R. E.
    Indiana Univ, Bloomington, IN 47405 USA..
    Mo, X. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Mo, Y. J.
    Cent China Normal Univ, Wuhan 430079, Peoples R China..
    Morales, C. Morales
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Muchnoi, N. Yu.
    GI Budker Inst Nucl Phys SB RAS BINP, Novosibirsk 630090, Russia..
    Muramatsu, H.
    Univ Minnesota, Minneapolis, MN 55455 USA..
    Musiol, P.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Nefedov, Y.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Nerling, F.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Nikolaev, I. B.
    GI Budker Inst Nucl Phys SB RAS BINP, Novosibirsk 630090, Russia..
    Ning, Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Nisar, S.
    COMSATS Inst Informat Technol, Lahore 54000, Pakistan..
    Niu, S. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Niu, X. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Olsen, S. L.
    Seoul Natl Univ, Seoul 151747, South Korea..
    Ouyang, Q.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Pacetti, S.
    INFN, I-06100 Perugia, Italy.;Univ Perugia, I-06100 Perugia, Italy..
    Pan, Y.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Patteri, P.
    INFN Lab Nazl Frascati, I-00044 I- Frascati, Italy..
    Pelizaeus, M.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Peng, H. P.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Peters, K.
    GSI Helmholtzcentre Heavy Ion Res GmbH, D-64291 Darmstadt, Germany..
    Pettersson, Joachim
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Ping, J. L.
    Nanjing Normal Univ, Nanjing 210023, Peoples R China..
    Ping, R. G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Poling, R.
    Univ Minnesota, Minneapolis, MN 55455 USA..
    Prasad, V.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Qi, H. R.
    Beihang Univ, Beijing 100191, Peoples R China..
    Qi, M.
    Nanjing Univ, Nanjing 210093, Peoples R China..
    Qian, S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Qiao, C. F.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Qin, L. Q.
    Shandong Univ, Jinan 250100, Peoples R China..
    Qin, N.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Qin, X. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Qin, Z. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Qiu, J. F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Rashid, K. H.
    Univ Punjab, Lahore 54590, Pakistan..
    Redmer, C. F.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Ripka, M.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Rong, G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Rosner, Ch.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Ruan, X. D.
    Guangxi Univ, Nanning 530004, Peoples R China..
    Sarantsev, A.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Savrie, M.
    Univ Ferrara, I-44122 Ferrara, Italy..
    Schnier, C.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Schönning, Karin
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics. Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, The Svedberg Laboratory.
    Schumann, S.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Shan, W.
    Peking Univ, Beijing 100871, Peoples R China..
    Shao, M.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Shen, C. P.
    Beihang Univ, Beijing 100191, Peoples R China..
    Shen, P. X.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Shen, X. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Sheng, H. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Shi, M.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Song, W. M.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Song, X. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Sosio, S.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Spataro, S.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Sun, G. X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Sun, J. F.
    Henan Normal Univ, Xinxiang 453007, Peoples R China..
    Sun, S. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Sun, X. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Sun, Y. J.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Sun, Y. Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Sun, Z. J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Sun, Z. T.
    Indiana Univ, Bloomington, IN 47405 USA..
    Tang, C. J.
    Sichuan Univ, Chengdu 610064, Peoples R China..
    Tang, X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Tapan, I.
    Uludag Univ, TR-16059 Bursa, Turkey..
    Thorndike, E. H.
    Univ Rochester, Rochester, NY 14627 USA..
    Tiemens, M.
    Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands..
    Uman, I.
    Near East Univ, Nicosia 10, Turkey..
    Varner, G. S.
    Univ Hawaii, Honolulu, HI 96822 USA..
    Wang, B.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Wang, B. L.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Wang, D.
    Peking Univ, Beijing 100871, Peoples R China..
    Wang, D. Y.
    Peking Univ, Beijing 100871, Peoples R China..
    Wang, K.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, L. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, L. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, M.
    Shandong Univ, Jinan 250100, Peoples R China..
    Wang, P.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, P. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, S. G.
    Peking Univ, Beijing 100871, Peoples R China..
    Wang, W.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, W. P.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Wang, X. F.
    Tsinghua Univ, Beijing 100084, Peoples R China..
    Wang, Y.
    Soochow Univ, Suzhou 215006, Peoples R China..
    Wang, Y. D.
    Helmholtz Inst Mainz, D-55099 Mainz, Germany..
    Wang, Y. F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, Y. Q.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Wang, Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, Z. G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wang, Z. H.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Wang, Z. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Weber, T.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Wei, D. H.
    Guangxi Normal Univ, Guilin 541004, Peoples R China..
    Wei, J. B.
    Peking Univ, Beijing 100871, Peoples R China..
    Weidenkaff, P.
    Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany..
    Wen, S. P.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wiedner, U.
    Ruhr Univ Bochum, D-44780 Bochum, Germany..
    Wolke, Magnus
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Wu, L. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wu, L. J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Wu, Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Xia, L.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Xia, L. G.
    Tsinghua Univ, Beijing 100084, Peoples R China..
    Xia, Y.
    Hunan Univ, Changsha 410082, Peoples R China..
    Xiao, D.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Xiao, H.
    Univ South China, Hengyang 421001, Peoples R China..
    Xiao, Z. J.
    Nanjing Normal Univ, Nanjing 210023, Peoples R China..
    Xie, Y. G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Xiu, Q. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Xu, G. F.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Xu, J. J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Xu, L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Xu, Q. J.
    Hangzhou Normal Univ, Hangzhou 310036, Peoples R China..
    Xu, Q. N.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Xu, X. P.
    Soochow Univ, Suzhou 215006, Peoples R China..
    Yan, L.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Yan, W. B.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Yan, W. C.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Yan, Y. H.
    Hunan Univ, Changsha 410082, Peoples R China..
    Yang, H. J.
    Shanghai Jiao Tong Univ, Shanghai 200240, Peoples R China..
    Yang, H. X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Yang, L.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Yang, Y. X.
    Guangxi Normal Univ, Guilin 541004, Peoples R China..
    Ye, M.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Ye, M. H.
    China Ctr Adv Sci & Technol, Beijing 100190, Peoples R China..
    Yin, J. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Yu, B. X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Yu, C. X.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Yu, J. S.
    Lanzhou Univ, Lanzhou 730000, Peoples R China..
    Yuan, C. Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Yuan, W. L.
    Nanjing Univ, Nanjing 210093, Peoples R China..
    Yuan, Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Yuncu, A.
    Istanbul Bilgi Univ, TR-34060 Istanbul, Turkey..
    Zafar, A. A.
    Univ Punjab, Lahore 54590, Pakistan..
    Zallo, A.
    INFN Lab Nazl Frascati, I-00044 I- Frascati, Italy..
    Zeng, Y.
    Hunan Univ, Changsha 410082, Peoples R China..
    Zeng, Z.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhang, B. X.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, B. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, C.
    Nanjing Univ, Nanjing 210093, Peoples R China..
    Zhang, C. C.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, D. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, H. H.
    Sun Yat Sen Univ, Guangzhou 510275, Guangdong, Peoples R China..
    Zhang, H. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, J. J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, J. L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, J. Q.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, J. W.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, J. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, J. Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, K.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, S. Q.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Zhang, X. Y.
    Shandong Univ, Jinan 250100, Peoples R China..
    Zhang, Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, Y. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhang, Y. N.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Zhang, Y. T.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhang, Yu
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Zhang, Z. H.
    Cent China Normal Univ, Wuhan 430079, Peoples R China..
    Zhang, Z. P.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhang, Z. Y.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Zhao, G.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, J. W.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, J. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, J. Z.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, Lei
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhao, Ling
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, M. G.
    Nankai Univ, Tianjin 300071, Peoples R China..
    Zhao, Q.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, Q. W.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, S. J.
    Zhengzhou Univ, Zhengzhou 450001, Peoples R China..
    Zhao, T. C.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, Y. B.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhao, Z. G.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhemchugov, A.
    Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia..
    Zheng, B.
    Univ South China, Hengyang 421001, Peoples R China..
    Zheng, J. P.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zheng, W. J.
    Shandong Univ, Jinan 250100, Peoples R China..
    Zheng, Y. H.
    Chinese Acad Sci, Beijing 100049, Peoples R China..
    Zhong, B.
    Nanjing Normal Univ, Nanjing 210023, Peoples R China..
    Zhou, L.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhou, X.
    Wuhan Univ, Wuhan 430072, Peoples R China..
    Zhou, X. K.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhou, X. R.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhou, X. Y.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhu, K.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhu, K. J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhu, S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhu, S. H.
    Univ Sci & Technol Liaoning, Anshan 114051, Peoples R China..
    Zhu, X. L.
    Tsinghua Univ, Beijing 100084, Peoples R China..
    Zhu, Y. C.
    Univ Sci & Technol China, Hefei 230026, Peoples R China..
    Zhu, Y. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhu, Z. A.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zhuang, J.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zotti, L.
    Univ Turin, I-10125 Turin, Italy.;INFN, I-10125 Turin, Italy..
    Zou, B. S.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Zou, J. H.
    Inst High Energy Phys, Beijing 100049, Peoples R China..
    Amplitude analysis of D0 → K -π+π+π-2017In: Physical Review D: covering particles, fields, gravitation, and cosmology, ISSN 2470-0010, E-ISSN 2470-0029, Vol. 95, no 7, article id 072010Article in journal (Refereed)
    Abstract [en]

    We present an amplitude analysis of the decay D0 → K -π+π+π- based on a data sample of 2.93  fb−1 acquired by the BESIII detector at the ψ(3770) resonance. With a nearly background free sample of about 16000 events, we investigate the substructure of the decay and determine the relative fractions and the phases among the different intermediate processes. Our amplitude model includes the two-body decays D0 → ¯K*0ρ0, D0 → Ka+1(1260) and D0 → K1(1270)π+, the three-body decays D0 →¯K*0π+π and D0 → Kπ+ρ0, as well as the four-body nonresonant decay D0 → Kπ+π+π. The dominant intermediate process is D0 → Ka+1(1260), accounting for a fit fraction of 54.6%.

  • 42.
    Abolhassani, Hassan
    et al.
    Karolinska Inst, Dept Biosci & Nutr, S-14183 Huddinge, Sweden.;Univ Tehran Med Sci, Res Ctr Immunodeficiencies, Pediat Ctr Excellence, Childrens Med Ctr, Tehran, Iran.
    Vosughimotlagh, Ahmad
    North Khorasan Univ Med Sci, Dept Pediat, Bojnurd, Iran.
    Asano, Takaki
    Rockefeller Univ, Rockefeller Branch, St Giles Lab Human Genet Infect Dis, 1230 York Ave, New York, NY 10021 USA.
    Landegren, Nils
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Autoimmunity. Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical diabetology and metabolism. Karolinska Inst, Ctr Mol Med, Dept Med Solna, Stockholm, Sweden.
    Boisson, Bertrand
    Rockefeller Univ, Rockefeller Branch, St Giles Lab Human Genet Infect Dis, 1230 York Ave, New York, NY 10021 USA.;Necker Hosp Sick Children, Necker Branch, Lab Human Genet Infect Dis, INSERM U1163, Paris, France.;Univ Paris, Imagine Inst, Paris, France.
    Delavari, Samaneh
    Univ Tehran Med Sci, Res Ctr Immunodeficiencies, Pediat Ctr Excellence, Childrens Med Ctr, Tehran, Iran.
    Bastard, Paul
    Necker Hosp Sick Children, Necker Branch, Lab Human Genet Infect Dis, INSERM U1163, Paris, France.;Univ Paris, Imagine Inst, Paris, France.
    Aranda-Guillen, Maribel
    Karolinska Inst, Ctr Mol Med, Dept Med Solna, Stockholm, Sweden.
    Wang, Yating
    Karolinska Inst, Dept Biosci & Nutr, S-14183 Huddinge, Sweden.
    Zuo, Fanglei
    Karolinska Inst, Dept Biosci & Nutr, S-14183 Huddinge, Sweden.
    Sardh, Fabian
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology. Karolinska Inst, Ctr Mol Med, Dept Med Solna, Stockholm, Sweden..
    Marcotte, Harold
    Karolinska Inst, Dept Lab Med, Stockholm, Sweden.;Karolinska Univ, Hosp Huddinge, Stockholm, Sweden.
    Du, Likun
    Karolinska Inst, Dept Biosci & Nutr, S-14183 Huddinge, Sweden.
    Zhang, Shen-Ying
    Rockefeller Univ, Rockefeller Branch, St Giles Lab Human Genet Infect Dis, 1230 York Ave, New York, NY 10021 USA.
    Zhang, Qian
    Rockefeller Univ, Rockefeller Branch, St Giles Lab Human Genet Infect Dis, 1230 York Ave, New York, NY 10021 USA.
    Rezaei, Nima
    Univ Tehran Med Sci, Res Ctr Immunodeficiencies, Pediat Ctr Excellence, Childrens Med Ctr, Tehran, Iran.
    Kampe, Olle
    Karolinska Inst, Ctr Mol Med, Dept Med Solna, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Endocrinol Metab & Diabet, Stockholm, Sweden.
    Casanova, Jean-Laurent
    Rockefeller Univ, Rockefeller Branch, St Giles Lab Human Genet Infect Dis, 1230 York Ave, New York, NY 10021 USA.;Necker Hosp Sick Children, Necker Branch, Lab Human Genet Infect Dis, INSERM U1163, Paris, France.;Univ Paris, Imagine Inst, Paris, France.;Howard Hughes Med Inst, New York, NY USA.
    Hammarstrom, Lennart
    Karolinska Inst, Dept Biosci & Nutr, S-14183 Huddinge, Sweden.
    Pan-Hammarstrom, Qiang
    Karolinska Inst, Dept Biosci & Nutr, S-14183 Huddinge, Sweden.
    X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia2022In: Journal of Clinical Immunology, ISSN 0271-9142, E-ISSN 1573-2592, Vol. 42, no 1, p. 1-9Article in journal (Refereed)
    Abstract [en]

    Background Coronavirus disease 2019 (COVID-19) exhibits a wide spectrum of clinical manifestations, ranging from asymptomatic to critical conditions. Understanding the mechanism underlying life-threatening COVID-19 is instrumental for disease prevention and treatment in individuals with a high risk.

    Objectives We aimed to identify the genetic cause for critical COVID-19 pneumonia in a patient with a preexisting inborn error of immunity (IEI).

    Methods Serum levels of specific antibodies against the virus and autoantibodies against type I interferons (IFNs) were measured. Whole exome sequencing was performed, and the impacts of candidate gene variants were investigated. We also evaluated 247 ataxia-telangiectasia (A-T) patients in the Iranian IEI registry.

    Results We report a 7-year-old Iranian boy with a preexisting hyper IgM syndrome who developed critical COVID-19 pneumonia. IgM only specific COVID-19 immune response was detected but no autoantibodies against type I IFN were observed. A homozygous deleterious mutation in the ATM gene was identified, which together with his antibody deficiency, radiosensitivity, and neurological signs, established a diagnosis of A-T. Among the 247 A-T patients evaluated, 36 had SARS-CoV-2 infection, but all had mild symptoms or were asymptomatic except the index patient. A hemizygous deleterious mutation in the TLR7 gene was subsequently identified in the patient.

    Conclusions We report a unique IEI patient with combined ATM and TLR7 deficiencies. The two genetic defects underlie A-T and critical COVID-19 in this patient, respectively.

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  • 43.
    Abou-Soultan, Nariman
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Sandström, Robert
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Patienters erfarenheter av smärtbehandling på en akutmottagning med fokus på patientens grundläggande vårdbehov: En deskriptiv litteraturstudie med induktiv ansats2022Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Den mest förekommande orsaken till att patienter besöker akutmottagningen ärsmärta och i Sverige besöker cirka 1,6 miljoner människor akutmottagningar varje år. Underbehandling av smärta har varit och är fortfarande ett stort problem på akutmottagningenoch patienter är inte tillfredsställda med smärtbehandlingen de får. Fel eller fördröjdbehandling av akuta smärttillstånd ökar risken för långvarig smärta.

    Syfte: Att beskriva patienters erfarenheter av smärtbehandling på en akutmottagning med fokus på deras grundläggande vårdbehov.

    Metod: En deskriptiv litteraturstudie med induktiv design tillämpades. Sökningarnagenomfördes i PubMed, CINAHL och Google Scholar vilket resulterade i 23 vetenskapligastudier med kvantitativ och kvalitativ ansats samt en med mixad-metod. Insamlade dataanalyserades med hjälp av integrerad innehållsanalys.

    Resultat: De faktorer som sågs påverka patienter erfarenheter av smärtbehandling och derastillfredsställelse var fysiska behov, vårdrelationen och psykosociala behov. De fysiskabehoven gällde smärtbedömning, tiden till smärtlindring samt adekvat smärtlindring ochvårdrelationen gällde interaktionen mellan patient och vårdpersonal samt visad empati hospersonalen. Psykosociala behov i form av information och kommunikation samt emotionelltvälbefinnande hade också betydelse.

    Slutsats: Huvudresultatet i denna litteraturstudie visar på att patienters vårdrelation med vårdpersonal och patienters fysiska samt psykosociala behov var av stor vikt för patienters erfarenheter av smärtbehandling, dock var behoven inte alltid tillgodosedda. En nationell behandlingsriktlinje kring smärtbehandling och betydelsen av personcentrerad vård på akutmottagningen kan vara patienter till gagn. Med ramverket Fundamentals of Care går det att identifiera patientens grundläggande vårdbehov som kan vägleda sjuksköterskor att ge enholistisk och personcentrerad vård samt en god omvårdnad vid smärtbehandling. 

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  • 44. Abraham-Nordling, Mirna
    et al.
    Byström, Kristina
    Törring, Ove
    Lantz, Mikael
    Berg, Gertrud
    Calissendorff, Jan
    Nyström, Helena Filipsson
    Jansson, Svante
    Jörneskog, Gun
    Karlsson, F Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Nyström, Ernst
    Ohrling, Hans
    Orn, Thomas
    Hallengren, Bengt
    Wallin, Göran
    Incidence of hyperthyroidism in Sweden2011In: European Journal of Endocrinology, ISSN 0804-4643, E-ISSN 1479-683X, Vol. 165, no 6, p. 899-905Article in journal (Refereed)
    Abstract [en]

    Introduction The incidence of hyperthyroidism has been reported in various countries to be 23-93/100 000 inhabitants per year. This extended study has evaluated the incidence for ∼40% of the Swedish population of 9 million inhabitants. Sweden is considered to be iodine sufficient country. Methods All patients including children, who were newly diagnosed with overt hyperthyroidism in the years 2003-2005, were prospectively registered in a multicenter study. The inclusion criteria are as follows: clinical symptoms and/or signs of hyperthyroidism with plasma TSH concentration below 0.2 mIE/l and increased plasma levels of free/total triiodothyronine and/or free/total thyroxine. Patients with relapse of hyperthyroidism or thyroiditis were not included. The diagnosis of Graves' disease (GD), toxic multinodular goiter (TMNG) and solitary toxic adenoma (STA), smoking, initial treatment, occurrence of thyroid-associated eye symptoms/signs, and demographic data were registered. Results A total of 2916 patients were diagnosed with de novo hyperthyroidism showing the total incidence of 27.6/100 000 inhabitants per year. The incidence of GD was 21.0/100 000 and toxic nodular goiter (TNG=STA+TMNG) occurred in 692 patients, corresponding to an annual incidence of 6.5/100 000. The incidence was higher in women compared with men (4.2:1). Seventy-five percent of the patients were diagnosed with GD, in whom thyroid-associated eye symptoms/signs occurred during diagnosis in every fifth patient. Geographical differences were observed. Conclusion The incidence of hyperthyroidism in Sweden is in a lower range compared with international reports. Seventy-five percent of patients with hyperthyroidism had GD and 20% of them had thyroid-associated eye symptoms/signs during diagnosis. The observed geographical differences require further studies.

  • 45. Abrahamsson, Christina
    et al.
    Ahlund, Catherine
    Nordlander, Margareta
    Lind, Lars
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    A method for heart rate-corrected estimation of baroreflex sensitivity.2003In: J Hypertens, ISSN 0263-6352, Vol. 21, no 11, p. 2133-40Article in journal (Refereed)
  • 46.
    Abrahamsson, Niclas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    On the Impact of Bariatric Surgery on Glucose Homeostasis2016Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Obesity has grown to epidemic proportions, and in lack of efficient life-style and medical treatments, the bariatric surgeries are performed in rising numbers. The most common surgery is the Gastric Bypass (GBP) surgery, with the Biliopancreatic diversion with duodenal switch (DS) as an option for the most extreme cases with a BMI>50 kg/m2.

    In paper I 20 GBP-patients were examined during the first post-operative year regarding the natriuretic peptide, NT-ProBNP, which is secreted from the cardiac ventricles. Levels of NT-ProBNP quickly increased during the first post-surgery week, and later established itself on a higher level than pre-surgery.

    In paper II we report of 5 patient-cases after GBP-surgery with severe problems with postprandial hypoglycaemia that were successfully treated with GLP-1-analogs. The effect of treatment could be observed both symptomatically and in some cases using continuous glucose measuring systems (CGMS).

    In paper III three groups of subjects; 15 post-GBP patients, 15 post-DS, and 15 obese controls were examined for three days using CGMS during everyday life. The post-GBP group had high glucose variability as measured by MAGE and CONGA, whereas the post-DS group had low variability. Both post-operative groups exhibited significant time in hypoglycaemia, about 40 and 80 minutes per day <3.3mmol/l and 20 and 40 minutes < 2.8mmol/l, respectively, longer time for DS-group. Remarkably, only about 20% of these hypoglycaemic episodes were accompanied with symptoms.

    In Paper IV the hypoglycaemia counter regulatory system was investigated; 12 patients were examined before and after GBP-surgery with a stepped hypoglycaemic hyperinsulinemic clamp. The results show a downregulation of symptoms, counter regulatory hormones (glucagon, cortisol, epinephrine, norepinephrine, growth hormone), incretin hormones (GLP-1 and GIP), and sympathetic nervous response.

    In conclusion patients post bariatric surgery exhibit a downregulated counter regulatory response to hypoglycaemia, accompanied by frequent asymptomatic hypoglycaemic episodes in everyday life. Patients suffering from severe hypoglycaemic episodes can often be treated successfully with GLP-1-analogues.

    List of papers
    1. Gastric Bypass Surgery Elevates NT-ProBNP Levels
    Open this publication in new window or tab >>Gastric Bypass Surgery Elevates NT-ProBNP Levels
    2013 (English)In: Obesity Surgery, ISSN 0960-8923, E-ISSN 1708-0428, Vol. 23, no 9, p. 1421-1426Article in journal (Refereed) Published
    Abstract [en]

    Background

    Brain natriuretic peptide (BNP) is produced in the heart in response to stretching of the myocardium. BNP levels are negatively correlated to obesity, and in obese subjects, a reduced BNP responsiveness has been described. Diet-induced weight loss has been found to lower or to have no effect on BNP levels, whereas gastric banding and gastric bypass have reported divergent results. We studied obese patients undergoing gastric bypass (GBP) surgery during follow-up of 1 year.

    Methods

    Twenty patients, 18 women, mean 41 (SD 9.5) years old, with a mean preoperative BMI of 44.6 (SD 5.5) kg/m2 were examined. N-terminal pro-brain natriuretic peptide (NT-ProBNP), glucose and insulin were measured preoperatively, at day 6 and months 1, 6 and 12. In 14 of the patients, samples were also taken at days 1, 2 and 4.

    Results

    The NT-ProBNP levels showed a marked increase during the postoperative week (from 54 pg/mL preop to 359 pg/mL on day 2 and fell to 155 on day 6). At 1 year, NT-ProBNP was 122 pg/mL (125 % increase, p = 0.01). Glucose, insulin and HOMA indices decreased shortly after surgery without correlation to NT-ProBNP change. Mean BMI was reduced from 44.6 to 30.5 kg/m2 at 1 year and was not related to NT-ProBNP change.

    Conclusions

    The data indicate that GBP surgery rapidly alters the tone of BNP release, by a mechanism not related to weight loss or to changes in glucometabolic parameters. The GBP-induced conversion of obese subjects, from low to high NT-ProBNP responders, is likely to influence the evaluation of cardiac function in GBP operated individuals.

    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:uu:diva-199870 (URN)10.1007/s11695-013-0889-z (DOI)000322494800011 ()23456799 (PubMedID)
    Available from: 2013-05-17 Created: 2013-05-17 Last updated: 2017-12-06Bibliographically approved
    2. GLP1 analogs as treatment of postprandial hypoglycemia following gastric bypass surgery: a potential new indication?
    Open this publication in new window or tab >>GLP1 analogs as treatment of postprandial hypoglycemia following gastric bypass surgery: a potential new indication?
    2013 (English)In: European Journal of Endocrinology, ISSN 0804-4643, E-ISSN 1479-683X, Vol. 169, no 6, p. 885-889Article in journal (Refereed) Published
    Abstract [en]

    Objective: The number of morbidly obese subjects submitted to bariatric surgery is rising worldwide. In a fraction of patients undergoing gastric bypass (GBP), episodes with late postprandial hypoglycemia (PPHG) develop 1-3 years after surgery. The pathogenesis of this phenomenon is not fully understood; meal-induced rapid and exaggerated increases of circulating incretins and insulin appear to be at least partially responsible. Current treatments include low-carbohydrate diets, inhibition of glucose intestinal uptake, reduction of insulin secretion with calcium channel blockers, somatostatin analogs, or diazoxide, a KATP channel opener. Even partial pancreatectomy has been advocated. In type 2 diabetes, GLP1 analogs have a well-documented effect of stabilizing glucose levels without causing hypoglycemia. Design: We explored GLP1 analogs as open treatment in five consecutive GBP cases seeking medical attention because of late postprandial hypoglycemic symptoms. Results: Glucose measured in connection with the episodes in four of the cases had been 2.7, 2.5, 1.8, and 1.6 mmol/l respectively. The patients consistently described that the analogs eliminated their symptoms, which relapsed in four of the five patients when treatment was reduced/discontinued. The drug effect was further documented in one case by repeated 24-h continuous glucose measurements. Conclusion: These open, uncontrolled observations suggest that GLP1 analogs might provide a new treatment option in patients with problems of late PPHG.

    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:uu:diva-213465 (URN)10.1530/EJE-13-0504 (DOI)000327539100021 ()
    Available from: 2014-01-02 Created: 2013-12-23 Last updated: 2017-12-06Bibliographically approved
    3. Hypoglycemia in everyday life after gastric bypass and duodenal switch
    Open this publication in new window or tab >>Hypoglycemia in everyday life after gastric bypass and duodenal switch
    2015 (English)In: European Journal of Endocrinology, ISSN 0804-4643, E-ISSN 1479-683X, Vol. 173, no 1, p. 91-100Article in journal (Refereed) Published
    Abstract [en]

    Design: Gastric bypass (GBP) and duodenal switch (DS) in morbid obesity are accompanied by marked metabolic improvements, particularly in glucose control. In recent years, episodes of severe late postprandial hypoglycemia have been increasingly described in GBP patients; data in DS patients are scarce. We recruited three groups of subjects; 15 GBP, 15 DS, and 15 non-operated overweight controls to examine to what extent hypoglycemia occurs in daily life. Methods: Continuous glucose monitoring (CGM) was used during 3 days of normal activity. The glycemic variability was measured by mean amplitude of glycemic excursion and continuous overall net glycemic action. Fasting blood samples were drawn, and the patients kept a food and symptom log throughout the study. Results: The GBP group displayed highly variable CGM curves, and 2.9% of their time was spent in hypoglycemia (< 3.3 mmol/l, or 60 mg/dl). The DS group had twice as much time in hypoglycemia (5.9%) and displayed CGM curves with little variation as well as lower HbA1c levels (29.3 vs 35.9 mmol/mol, P < 0.05). Out of a total of 72 hypoglycemic episodes registered over the 3-day period, 70 (97%) occurred in the postprandial state and only about one-fifth of the hypoglycemic episodes in the GBP and DS groups were accompanied by symptoms. No hypoglycemias were seen in controls during the 3-day period. Conclusion: Both types of bariatric surgery induce marked, but different, changes in glucose balance accompanied by frequent, but mainly unnoticed, hypoglycemic episodes. The impact and mechanism of hypoglycemic unawareness after weight-reduction surgery deserves to be clarified.

    National Category
    Endocrinology and Diabetes
    Identifiers
    urn:nbn:se:uu:diva-261313 (URN)10.1530/EJE-14-0821 (DOI)000358947700018 ()25899582 (PubMedID)
    Available from: 2015-09-03 Created: 2015-09-01 Last updated: 2017-12-04Bibliographically approved
    4. Gastric bypass reduces symptoms and hormonal responses to hypoglycemia
    Open this publication in new window or tab >>Gastric bypass reduces symptoms and hormonal responses to hypoglycemia
    Show others...
    2016 (English)In: Diabetes, ISSN 0012-1797, E-ISSN 1939-327X, Vol. 65, no 9, p. 2667-2675Article in journal (Refereed) Published
    Abstract [en]

    Gastric bypass (GBP) surgery, one of the most common bariatric procedures, induces weight loss and metabolic effects. The mechanisms are not fully understood, but reduced food intake and effects on gastrointestinal hormones are thought to contribute. We recently observed that GBP patients have lowered glucose levels and frequent asymptomatic hypoglycemic episodes. Here, we subjected patients before and after undergoing GBP surgery to hypoglycemia and examined symptoms and hormonal and autonomic nerve responses. Twelve obese patients without diabetes (8 women, mean age 43.1 years [SD 10.8] and BMI 40.6 kg/m(2) [SD 3.1]) were examined before and 23 weeks (range 19-25) after GBP surgery with hyperinsulinemic-hypoglycemic clamp (stepwise to plasma glucose 2.7 mmol/L). The mean change in Edinburgh Hypoglycemia Score during clamp was attenuated from 10.7 (6.4) before surgery to 5.2 (4.9) after surgery. There were also marked postsurgery reductions in levels of glucagon, cortisol, and catecholamine and the sympathetic nerve responses to hypoglycemia. In addition, growth hormone displayed a delayed response but to a higher peak level. Levels of glucagon-like peptide 1 and gastric inhibitory polypeptide rose during hypoglycemia but rose less postsurgery compared with presurgery. Thus, GBP surgery causes a resetting of glucose homeostasis, which reduces symptoms and neurohormonal responses to hypoglycemia. Further studies should address the underlying mechanisms as well as their impact on the overall metabolic effects of GBP surgery.

    Keywords
    Gastric bypass, hypoglycemia
    National Category
    Endocrinology and Diabetes
    Identifiers
    urn:nbn:se:uu:diva-276380 (URN)10.2337/db16-0341 (DOI)000382099800021 ()27313315 (PubMedID)
    Funder
    Swedish Diabetes Association
    Available from: 2016-02-12 Created: 2016-02-12 Last updated: 2017-11-30Bibliographically approved
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  • 47.
    Abrahamsson, Niclas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical diabetology and metabolism.
    Postprandial Normoglycemic Hypokalemia-an Overlooked Complication to Gastric Bypass Surgery?2021In: Obesity Surgery, ISSN 0960-8923, E-ISSN 1708-0428, Vol. 31, no 7, p. 3369-3371Article in journal (Refereed)
    Abstract [en]

    Obesity is one of the major health problems of the world, and one of the most common surgical treatments is the Roux-en-Y gastric bypass surgery. This can however lead to problems with postprandial hypoglycemia, but sometimes, the meal test does not render any signs of hypoglycemia. Here, 3 cases are presented with postprandial normoglycemic hypokalemia.

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  • 48.
    Abrahamsson, Niclas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical diabetology and metabolism.
    Response to Postprandial Hyperinsulinemic Normoglycemic Hypokalemic Response After Roux-en-Y Gastric Bypass Surgery2022In: Obesity Surgery, ISSN 0960-8923, E-ISSN 1708-0428, Vol. 32, no 7, p. 2468-2468Article in journal (Other academic)
  • 49.
    Abrahamsson, Niclas
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Ahlund, Lovisa
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Psychology.
    Ahrin, Elsa
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Psychology.
    Alfonsson, Sven
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Research group (Dept. of women´s and children´s health), Clinical Psychology in Healthcare.
    Video-based CBT-E improves eating patterns in obese patients with eating disorder: A single case multiple baseline study2018In: Journal of Behavior Therapy and Experimental Psychiatry, ISSN 0005-7916, E-ISSN 1873-7943, Vol. 61, p. 104-112Article in journal (Refereed)
    Abstract [en]

    BACKGROUND AND OBJECTIVES:

    Cognitive Behavioral Therapy (CBT) is effective for treating eating disorders but it may be difficult to reach patients living far from urban centers. Mobile video-based psychotherapy may potentially improve service reach but has not yet been evaluated. The purpose of this study was to investigate the effects of mobile video-based CBT for eating disorder and to explore the feasibility to use this technology in clinical care.

    METHODS:

    A controlled single case multiple baseline design was used which allowed for statistical analyses with randomization tests and non-overlap of all pairs (NAP). Five patients in the first stage of eating disorder treatment were included and the main outcome variable was daily meal frequency. Secondary outcome variables included eating disorder symptoms, psychological distress and treatment satisfaction.

    RESULTS:

    The treatment resulted in a significant (p < .01) increase in daily meal frequency with medium to large effect sizes (combined NAP = .89). Four participants reported reliable improvements in eating disorder symptoms and three reported improvements in mood. The participants reported high satisfaction with the treatment and with the mobile video-application despite some technical problems.

    LIMITATIONS:

    Self-reported data on eating behavior is prone to be biased and the results of single case studies may have limited generalizability.

    CONCLUSION:

    CBT can be delivered effectively via a mobile video application and, despite some technological issues, can be well received by patients. All participants in this study had previous low access to mental health services and reported high satisfaction with the treatment format.

  • 50.
    Abrahamsson, Niclas
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Endocrinology, Diabetes and Metabolism.
    Engström, Britt Edén
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Endocrinology, Diabetes and Metabolism.
    Sundbom, Magnus
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Upper Abdominal Surgery.
    Karlsson, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Endocrinology, Diabetes and Metabolism.
    Gastric Bypass Surgery Elevates NT-ProBNP Levels2013In: Obesity Surgery, ISSN 0960-8923, E-ISSN 1708-0428, Vol. 23, no 9, p. 1421-1426Article in journal (Refereed)
    Abstract [en]

    Background

    Brain natriuretic peptide (BNP) is produced in the heart in response to stretching of the myocardium. BNP levels are negatively correlated to obesity, and in obese subjects, a reduced BNP responsiveness has been described. Diet-induced weight loss has been found to lower or to have no effect on BNP levels, whereas gastric banding and gastric bypass have reported divergent results. We studied obese patients undergoing gastric bypass (GBP) surgery during follow-up of 1 year.

    Methods

    Twenty patients, 18 women, mean 41 (SD 9.5) years old, with a mean preoperative BMI of 44.6 (SD 5.5) kg/m2 were examined. N-terminal pro-brain natriuretic peptide (NT-ProBNP), glucose and insulin were measured preoperatively, at day 6 and months 1, 6 and 12. In 14 of the patients, samples were also taken at days 1, 2 and 4.

    Results

    The NT-ProBNP levels showed a marked increase during the postoperative week (from 54 pg/mL preop to 359 pg/mL on day 2 and fell to 155 on day 6). At 1 year, NT-ProBNP was 122 pg/mL (125 % increase, p = 0.01). Glucose, insulin and HOMA indices decreased shortly after surgery without correlation to NT-ProBNP change. Mean BMI was reduced from 44.6 to 30.5 kg/m2 at 1 year and was not related to NT-ProBNP change.

    Conclusions

    The data indicate that GBP surgery rapidly alters the tone of BNP release, by a mechanism not related to weight loss or to changes in glucometabolic parameters. The GBP-induced conversion of obese subjects, from low to high NT-ProBNP responders, is likely to influence the evaluation of cardiac function in GBP operated individuals.

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