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  • 1.
    Lightfoot, J. Timothy
    et al.
    Texas A&M Univ, Dept Hlth & Kinesiol, College Stn, TX USA;Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands.
    De Geus, Eco J. C.
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Vrije Univ Amsterdam, Dept Biol Psychol, Amsterdam, Netherlands.
    Booth, Frank W.
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Univ Missouri, Dept Nutr & Exercise Physiol, Columbia, MO USA;Univ Missouri, Dept Biomed Sci, Columbia, MO USA.
    Bray, Molly S.
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Univ Texas Austin, Dept Nutr Sci, Austin, TX USA.
    den Hoed, Marcel
    Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Medicinsk genetik och genomik. Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands.
    Kaprio, Jaakko
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Univ Helsinki, Dept Publ Hlth, Helsinki, Finland;Univ Helsinki, Inst Mol Med FIMM, Helsinki, Finland.
    Kelly, Scott A.
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Ohio Wesleyan Univ, Dept Zool, Delaware, OH 43015 USA.
    Pomp, Daniel
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Univ N Carolina, Dept Genet, Chapel Hill, NC USA.
    Saul, Michael C.
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Univ Illinois, Carl R Woese Inst Genom Biol, Urbana, IL USA.
    Thomis, Martine A.
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Katholieke Univ Leuven, Dept Movement Sci, Fac Kinesiol & Rehabil Sci, Leuven, Belgium.
    Garland, Theodore, Jr.
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Univ Calif Riverside, Dept Evolut Ecol & Organismal Biol, Riverside, CA 92521 USA.
    Bouchard, Claude
    Vrije Univ Amsterdam, Genet & Biol Determinants Phys Act Consortium Gen, Amsterdam, Netherlands;Pennington Biomed Res Ctr, Human Genom Lab, 6400 Perkins Rd, Baton Rouge, LA 70808 USA.
    Biological/Genetic Regulation of Physical Activity Level: Consensus From Genbiopac2018In: Medicine & Science in Sports & Exercise, ISSN 0195-9131, E-ISSN 1530-0315, Vol. 50, no 4, p. 863-873Article, review/survey (Refereed)
    Abstract [en]

    Purpose: Physical activity unquestionably maintains and improves health; however, physical activity levels globally are low and not rising despite all the resources devoted to this goal. Attention in both the research literature and the public policy domain has focused on social-behavioral factors; however, a growing body of literature suggests that biological determinants play a significant role in regulating physical activity levels. For instance, physical activity level, measured in various manners, has a genetic component in both humans and nonhuman animal models. This consensus article, developed as a result of an American College of Sports Medicine-sponsored round table, provides a brief review of the theoretical concepts and existing literature that supports a significant role of genetic and other biological factors in the regulation of physical activity.

    Conclusions: Future research on physical activity regulation should incorporate genetics and other biological determinants of physical activity instead of a sole reliance on social and other environmental determinants.

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