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  • 1. Bergström, Sten-Erik
    et al.
    Boman, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Respiratory Medicine and Allergology.
    Eriksson, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Forensic Medicine.
    Formgren, Hans
    Foucard, Tony
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Pediatrics.
    Hörte, Lars-Gunnar
    Janson, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Respiratory Medicine and Allergology.
    Spetz-Nyström, Ulrike
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Respiratory Medicine and Allergology.
    Hedlin, Gunilla
    Asthma mortality among Swedish children and young adults, a 10-year study2008In: Respiratory Medicine, ISSN 0954-6111, E-ISSN 1532-3064, Vol. 102, no 9, p. 1335-1341Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Previous reports indicate that morbidity and mortality from asthma have increased during the past decades. Here, the mortality rate associated with asthma and possible risk factors in children and young adults in Sweden during the period 1994-2003 were evaluated. METHODS: The medical profession was asked to report suspected cases of death from asthma in individuals 1-34 years of age. All death certificates containing relevant ICD codes were reviewed. Medical records and autopsy reports were assessed and telephone interviews with next-of-kin performed. RESULTS: During the 10-year period 37 deaths due to asthma were identified. The median age at the time of death was 27 years and 6 of the deceased were younger than 15. The overall incidence of death from asthma decreased from 1.54 deaths per million in 1994 to 0.53 per million in 2003. Common risk factors were under-treatment (23/37), poor adherence to prescribed treatment (17/37) and adverse psychosocial situation (19/37). An alarming finding was that 11 of the 37 deaths were probably caused by food allergy and for 8 subjects death was associated with exposure to pet dander. The death certificates were found to contain inaccuracies with 30% of those for whom asthma was reported as the underlying cause having died from other causes. CONCLUSION: Asthma mortality in children and young adults in Sweden decreased between 1994 and 2003. Food allergy and inadequate treatment were the major risk factors for such a death. Recognition and special care of patients with asthma who have shown signs of non-compliance, denial or severe food allergy must be encouraged.

  • 2.
    Boman, G
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Bergström, S-E
    Formgren, H
    Foucard, T
    Department of Women's and Children's Health.
    Hedlin, G
    Hörte, L-G
    Spetz-Nyström, U
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Fatal asthma in sweden is decreasing2002In: European Respiratory Journal, Vol. 20 Supplement 38, p. 199-Article, book review (Other (popular scientific, debate etc.))
  • 3.
    Sator, Lea
    et al.
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria.
    Horner, Andreas
    Kepler Univ Hosp, Dept Pulmonol, Krankenhausstr 9, A-4021 Linz, Austria;Johannes Kepler Univ Linz, Fac Med, Linz, Austria;Paracelsus Med Univ, Inst Gen Practice Family Med & Prevent Med, Salzburg, Austria.
    Studnicka, Michael
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria.
    Lamprecht, Bernd
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria;Kepler Univ Hosp, Dept Pulmonol, Krankenhausstr 9, A-4021 Linz, Austria;Johannes Kepler Univ Linz, Fac Med, Linz, Austria.
    Kaiser, Bernhard
    Kepler Univ Hosp, Dept Pulmonol, Krankenhausstr 9, A-4021 Linz, Austria.
    McBurnie, Mary Ann
    Kaiser Permanente Northwest, Ctr Hlth Res, Portland, OR USA.
    Buist, A. Sonia
    Oregon Hlth & Sci Univ, Portland, OR 97201 USA.
    Gnatiuc, Luisa
    Imperial Coll London, Resp Epidemiol & Publ Hlth Grp, London, England.
    Mannino, David M.
    Univ Kentucky, Dept Prevent Med & Environm Hlth, Coll Publ Hlth, Lexington, KY USA;Univ Kentucky, Lexington, KY USA.
    Janson, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Bateman, Eric D.
    Univ Cape Town, Div Pulmonol, Dept Med, Cape Town, South Africa.
    Burney, Peter
    Imperial Coll London, Resp Epidemiol & Publ Hlth Grp, London, England.
    Zhong, NanShan
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Guangdong, Peoples R China.
    Liu, Shengming
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Guangdong, Peoples R China.
    Lu, Jiachun
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Guangdong, Peoples R China.
    Ran, Pixin
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Guangdong, Peoples R China.
    Wang, Dali
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Guangdong, Peoples R China.
    Zheng, Jingping
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Guangdong, Peoples R China.
    Zhou, Yumin
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Guangdong, Peoples R China.
    Kocabas, Ali
    Cukurova Univ, Dept Chest Dis, Sch Med, Adana, Turkey.
    Hancioglu, Attila
    Cukurova Univ, Dept Chest Dis, Sch Med, Adana, Turkey.
    Hanta, Ismail
    Cukurova Univ, Dept Chest Dis, Sch Med, Adana, Turkey.
    Kuleci, Sedat
    Cukurova Univ, Dept Chest Dis, Sch Med, Adana, Turkey.
    Turkyilmaz, Ahmet Sinan
    Cukurova Univ, Dept Chest Dis, Sch Med, Adana, Turkey.
    Umut, Sema
    Cukurova Univ, Dept Chest Dis, Sch Med, Adana, Turkey.
    Unalan, Turgay
    Cukurova Univ, Dept Chest Dis, Sch Med, Adana, Turkey.
    Dawes, Torkil
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria.
    Bateman, Eric
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Jithoo, Anamika
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Adams, Desiree
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Barnes, Edward
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Freeman, Jasper
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Hayes, Anton
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Hlengwa, Sipho
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Johannisen, Christine
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Koopman, Mariana
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Louw, Innocentia
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Ludick, Ina
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Olckers, Alta
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Ryck, Johanna
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Storbeck, Janita
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Gislason, Thorarinn
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Benedikdtsdottir, Bryndis
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Jorundsdottir, Kristin
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Gudmundsdottir, Lovisa
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Gudmundsdottir, Sigrun
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Gundmundsson, Gunnar
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Nizankowska-Mogilnicka, Ewa
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Frey, Jakub
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Harat, Rafal
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Mejza, Filip
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Nastalek, Pawel
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Pajak, Andrzej
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Skucha, Wojciech
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Szczeklik, Andrzej
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Twardowska, Magda
    Jagiellonian Univ, Dept Med, Div Pulm Dis, Sch Med, Krakow, Poland.
    Welte, Tobias
    Hannover Med Sch, Hannover, Germany.
    Bodemann, Isabelle
    Hannover Med Sch, Hannover, Germany.
    Geldmacher, Henning
    Hannover Med Sch, Hannover, Germany.
    Schweda-Linow, Alexandra
    Hannover Med Sch, Hannover, Germany.
    Gulsvik, Amund
    Univ Bergen, Inst Med, Dept Thorac Med, Bergen, Norway.
    Endresen, Tina
    Univ Bergen, Inst Med, Dept Thorac Med, Bergen, Norway.
    Svendsen, Lene
    Univ Bergen, Inst Med, Dept Thorac Med, Bergen, Norway.
    Tan, Wan C.
    Univ British Columbia, iCapture Ctr Cardiovasc & Pulm Res, Vancouver, BC, Canada.
    Wang, Wen
    Univ British Columbia, iCapture Ctr Cardiovasc & Pulm Res, Vancouver, BC, Canada.
    Cain, John
    Univ Kentucky, Lexington, KY USA.
    Copeland, Rebecca
    Univ Kentucky, Lexington, KY USA.
    Hazen, Dana
    Univ Kentucky, Lexington, KY USA.
    Methvin, Jennifer
    Univ Kentucky, Lexington, KY USA.
    Dantes, Renato B.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Amarillo, Lourdes
    Philippine Coll Chest Phys, Manila, Philippines.
    Berratio, Lakan U.
    Philippine Coll Chest Phys, Manila, Philippines.
    Fernandez, Lenora C.
    Philippine Coll Chest Phys, Manila, Philippines.
    Francisco, Norberto A.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Roa, Camilo C.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Garcia, Gerard S.
    Philippine Coll Chest Phys, Manila, Philippines.
    de Guia, Teresita S.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Idolor, Luisito F.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Naval, Sullian S.
    Philippine Coll Chest Phys, Manila, Philippines.
    Reyes, Thessa
    Philippine Coll Chest Phys, Manila, Philippines.
    Flordeliza Sanchez, Ma
    Philippine Coll Chest Phys, Manila, Philippines.
    Simpao, Leander P.
    Philippine Coll Chest Phys, Manila, Philippines.
    Jenkins, Christine
    Woolcock Inst Med Res, Sydney, NSW, Australia.
    Marks, Guy
    Woolcock Inst Med Res, Sydney, NSW, Australia.
    Bird, Tessa
    Woolcock Inst Med Res, Sydney, NSW, Australia.
    Espinel, Paola
    Woolcock Inst Med Res, Sydney, NSW, Australia.
    Hardaker, Kate
    Woolcock Inst Med Res, Sydney, NSW, Australia.
    Toelle, Brett
    Woolcock Inst Med Res, Sydney, NSW, Australia.
    Burney, Peter G. J.
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Amor, Caron
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Potts, James
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Tumilty, Michael
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    McLean, Fiona
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Wouters, E. F. M.
    Maastricht Univ, Med Ctr, Maastricht, Netherlands.
    Wesseling, G. J.
    Maastricht Univ, Med Ctr, Maastricht, Netherlands.
    Barbara, Cristina
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Rodrigues, Fatima
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Dias, Herminia
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Cardoso, Joao
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Almeida, Joao
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Matos, Maria Joao
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Simao, Paula
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Santos, Moutinho
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Ferreira, Reis
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Olafsdottir, Inga Sif
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Nisser, Katarina
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Spetz-Nyström, Ulrike
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Hägg, Gunilla
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Lund, Gun-Marie
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Jogi, Rain
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Laja, Hendrik
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Ulst, Katrin
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Zobel, Vappu
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Lill, Toomas-Julius
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Koul, Parvaiz A.
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Malik, Sajjad
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Hakim, Nissar A.
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Khan, Umar Hafiz
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Chowgule, Rohini
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Shetye, Vasant
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Raphael, Jonelle
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Almeda, Rosel
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Tawde, Mahesh
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Tadvi, Rafiq
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Katkar, Sunil
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Kadam, Milind
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Dhanawade, Rupesh
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Ghurup, Umesh
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Harrabi, Imed
    Fac Med, Sousse, Tunisia.
    Denguezli, Myriam
    Fac Med, Sousse, Tunisia.
    Tabka, Zouhair
    Fac Med, Sousse, Tunisia.
    Daldoul, Hager
    Fac Med, Sousse, Tunisia.
    Boukheroufa, Zaki
    Fac Med, Sousse, Tunisia.
    Chouikha, Firas
    Fac Med, Sousse, Tunisia.
    Khalifa, Wahbi Belhaj
    Fac Med, Sousse, Tunisia.
    Roa, Camilo C., Jr.
    Philippine Coll Chest Phys, Manila, Philippines.
    Ayuyao, Fernando G.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Tady, Cecil Z.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Tan, Daniel T.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Banal-Yang, Sylvia
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Balanag, Vincent M., Jr.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Reyes, Maria Teresita N.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Juvekar, Sanjay
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Hirve, Siddhi
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Sambhudas, Somnath
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Chaidhary, Bharat
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Tambe, Meera
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Pingale, Savita
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Umap, Arati
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Umap, Archana
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Shelar, Nitin
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Devchakke, Sampada
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Chaudhary, Sharda
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Bondre, Suvarna
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Walke, Savita
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Gawhane, Ashleshsa
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Sapkal, Anil
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Argade, Rupali
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Gaikwad, Vijay
    KEM Hosp Res Ctr Pune, Vadu Hlth & Demog Surveillance, Pune, Maharashtra, India.
    Salvi, Sundeep
    Chest Res Fdn, Pune, Maharashtra, India.
    Brashier, Bill
    Chest Res Fdn, Pune, Maharashtra, India.
    Londhe, Jyoti
    Chest Res Fdn, Pune, Maharashtra, India.
    Madas, Sapna
    Chest Res Fdn, Pune, Maharashtra, India.
    Obaseki, Daniel
    Obafemi Awolowo Univ, Ife, Nigeria.
    Erhabor, Gregory
    Obafemi Awolowo Univ, Ife, Nigeria.
    Awopeju, Olayemi
    Obafemi Awolowo Univ, Ife, Nigeria.
    Adewole, Olufemi
    Obafemi Awolowo Univ, Ife, Nigeria.
    Overdiagnosis of COPD in Subjects With Unobstructed Spirometry A BOLD Analysis2019In: Chest, ISSN 0012-3692, E-ISSN 1931-3543, Vol. 156, no 2, p. 277-288Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: There are several reports on underdiagnosis of COPD, while little is known about COPD overdiagnosis and overtreatment. We describe the overdiagnosis and the prevalence of spirometrically defined false positive COPD, as well as their relationship with overtreatment across 23 population samples in 20 countries participating in the BOLD Study between 2003 and 2012.

    METHODS: A false positive diagnosis of COPD was considered when participants reported a doctor's diagnosis of COPD, but postbronchodilator spirometry was unobstructed (FEV1/FVC > LLN). Additional analyses were performed using the fixed ratio criterion (FEV1/FVC < 0.7).

    RESULTS: Among 16,177 participants, 919 (5.7%) reported a previous medical diagnosis of COPD. Postbronchodilator spirometry was unobstructed in 569 subjects (61.9%): false positive COPD. A similar rate of overdiagnosis was seen when using the fixed ratio criterion (55.3%). In a subgroup analysis excluding participants who reported a diagnosis of "chronic bronchitis" or "emphysema" (n = 220), 37.7% had no airflow limitation. The site-specific prevalence of false positive COPD varied greatly, from 1.9% in low- to middle-income countries to 4.9% in high-income countries. In multivariate analysis, overdiagnosis was more common among women, and was associated with higher education; former and current smoking; the presence of wheeze, cough, and phlegm; and concomitant medical diagnosis of asthma or heart disease. Among the subjects with false positive COPD, 45.7% reported current use of respiratory medication. Excluding patients with reported asthma, 34.4% of those with normal spirometry still used a respiratory medication.

    CONCLUSIONS: False positive COPD is frequent. This might expose nonobstructed subjects to possible adverse effects of respiratory medication.

  • 4.
    Studnicka, Michael
    et al.
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria.
    Horner, Andreas
    Kepler Univ Hosp, Dept Pulmonol, Krankenhausstr 9, A-4021 Linz, Austria;Johannes Kepler Univ Linz, Fac Med, Linz, Austria;Paracelsus Med Univ, Inst Gen Practice Family Med & Prevent Med, Salzburg, Austria.
    Sator, Lea
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria.
    Buist, A. Sonia
    Oregon Hlth & Sci Univ, Portland, OR 97201 USA.
    Lamprecht, Bernd
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria;Kepler Univ Hosp, Dept Pulmonol, Krankenhausstr 9, A-4021 Linz, Austria;Johannes Kepler Univ Linz, Fac Med, Linz, Austria.
    Zhong, NanShan
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China.
    Liu, Shengming
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China.
    Lu, Jiachun
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China.
    Ran, Pixin
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China.
    Wang, Dali
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China.
    Zheng, Jingping
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China.
    Zhou, Yumin
    Guangzhou Med Univ, Guangzhou Inst Resp Dis, Guangzhou, Peoples R China.
    Kocabas, Ali
    Cukurova Univ, Sch Med, Dept Chest Dis, Adana, Turkey.
    Hancioglu, Attila
    Cukurova Univ, Sch Med, Dept Chest Dis, Adana, Turkey.
    Hanta, Ismail
    Cukurova Univ, Sch Med, Dept Chest Dis, Adana, Turkey.
    Kuleci, Sedat
    Cukurova Univ, Sch Med, Dept Chest Dis, Adana, Turkey.
    Turkyilmaz, Ahmet Sinan
    Cukurova Univ, Sch Med, Dept Chest Dis, Adana, Turkey.
    Umut, Sema
    Cukurova Univ, Sch Med, Dept Chest Dis, Adana, Turkey.
    Unalan, Turgay
    Cukurova Univ, Sch Med, Dept Chest Dis, Adana, Turkey.
    Dawes, Torkil
    Paracelsus Med Univ, Dept Pulm Med, Salzburg, Austria.
    Bateman, Eric
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Jithoo, Anamika
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Adams, Desiree
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Barnes, Edward
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Freeman, Jasper
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Hayes, Anton
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Hlengwa, Sipho
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Johannisen, Christine
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Koopman, Mariana
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Louw, Innocentia
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Ludick, Ina
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Olckers, Alta
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Ryck, Johanna
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Storbeck, Janita
    Univ Cape Town, Lung Inst, Cape Town, South Africa.
    Gislason, Thorarinn
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Benedikdtsdottir, Bryndis
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Jorundsdottir, Kristin
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Gudmundsdottir, Lovisa
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Gudmundsdottir, Sigrun
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Gundmundsson, Gunnar
    Landspitali Univ Hosp, Dept Allergy Resp Med & Sleep, Reykjavik, Iceland.
    Nizankowska-Mogilnicka, Ewa
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Frey, Jakub
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Harat, Rafal
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Mejza, Filip
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Nastalek, Pawel
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Pajak, Andrzej
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Skucha, Wojciech
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Szczeklik, Andrzej
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Twardowska, Magda
    Jagiellonian Univ, Sch Med, Dept Med, Div Pulm Dis, Krakow, Poland.
    Welte, Tobias
    Hannover Med Sch, Hannover, Germany.
    Bodemann, Isabelle
    Hannover Med Sch, Hannover, Germany.
    Geldmacher, Henning
    Hannover Med Sch, Hannover, Germany.
    Schweda-Linow, Alexandra
    Hannover Med Sch, Hannover, Germany.
    Gulsvik, Amund
    Univ Bergen, Inst Med, Dept Thorac Med, Bergen, Norway.
    Endresen, Tina
    Univ Bergen, Inst Med, Dept Thorac Med, Bergen, Norway.
    Svendsen, Lene
    Univ Bergen, Inst Med, Dept Thorac Med, Bergen, Norway.
    Tan, Wan C.
    Univ British Columbia, ICapture Ctr Cardiovasc & Pulm Res, Vancouver, BC, Canada.
    Wang, Wen
    Univ British Columbia, ICapture Ctr Cardiovasc & Pulm Res, Vancouver, BC, Canada.
    Mannino, David M.
    Univ Kentucky, Lexington, KY USA.
    Cain, John
    Univ Kentucky, Lexington, KY USA.
    Copeland, Rebecca
    Univ Kentucky, Lexington, KY USA.
    Hazen, Dana
    Univ Kentucky, Lexington, KY USA.
    Methvin, Jennifer
    Univ Kentucky, Lexington, KY USA.
    Amarillo, Lourdes
    Philippine Coll Chest Phys, Manila, Philippines.
    Berratio, Lakan U.
    Philippine Coll Chest Phys, Manila, Philippines.
    Fernandez, Lenora C.
    Philippine Coll Chest Phys, Manila, Philippines.
    Francisco, Norberto A.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Garcia, Gerard S.
    Philippine Coll Chest Phys, Manila, Philippines.
    de Guia, Teresita S.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Idolor, Luisito F.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Naval, Sullian S.
    Philippine Coll Chest Phys, Manila, Philippines.
    Reyes, Thessa
    Philippine Coll Chest Phys, Manila, Philippines.
    Roa, Camilo C., Jr.
    Sanchez, Flordeliza
    Philippine Coll Chest Phys, Manila, Philippines.
    Simpao, Leander P.
    Philippine Coll Chest Phys, Manila, Philippines.
    Jenkins, Christine
    Woolock Inst Med Res, Sydney, NSW, Australia.
    Marks, Guy
    Woolock Inst Med Res, Sydney, NSW, Australia.
    Bird, Tessa
    Woolock Inst Med Res, Sydney, NSW, Australia.
    Espinel, Paola
    Woolock Inst Med Res, Sydney, NSW, Australia.
    Hardaker, Kate
    Woolock Inst Med Res, Sydney, NSW, Australia.
    Toelle, Brett
    Woolock Inst Med Res, Sydney, NSW, Australia.
    Burney, Peter G. J.
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Amor, Caron
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Potts, James
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Tumilty, Michael
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    McLean, Fiona
    Imperial Coll, Natl Heart & Lung Inst, London, England.
    Wouters, E. F. M.
    Maastricht Univ, Med Ctr, Maastricht, Netherlands.
    Wesseling, G. J.
    Maastricht Univ, Med Ctr, Maastricht, Netherlands.
    Barbara, Cristina
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Rodrigues, Fatima
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Dias, Herminia
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Cardoso, Joao
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Almeida, Joao
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Matos, Maria Joao
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Simao, Paula
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Santos, Moutinho
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Ferreira, Reis
    Portuguese Soc Pneumol, Lisbon, Portugal.
    Janson, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Olafsdottir, Inga Sif
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Nisser, Katarina
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Spetz-Nyström, Ulrike
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Hägg, Gunilla
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Lund, Gun-Marie
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Jogi, Rain
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Laja, Hendrik
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Ulst, Katrin
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Zobel, Vappu
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Lill, Toomas-Julius
    Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
    Koul, Parvaiz A.
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Malik, Sajjad
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Hakim, Nissar A.
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Khan, Umar Hafiz
    Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India.
    Chowgule, Rohini
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Shetye, Vasant
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Raphael, Jonelle
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Almeda, Rosel
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Tawde, Mahesh
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Tadvi, Rafiq
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Katkar, Sunil
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Kadam, Milind
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Dhanawade, Rupesh
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Ghurup, Umesh
    Indian Inst Environm Med, Mumbai, Maharashtra, India.
    Harrabi, Imed
    Fac Med, Sousse, Tunisia.
    Denguezli, Myriam
    Fac Med, Sousse, Tunisia.
    Tabka, Zouhair
    Fac Med, Sousse, Tunisia.
    Daldoul, Hager
    Fac Med, Sousse, Tunisia.
    Boukheroufa, Zaki
    Fac Med, Sousse, Tunisia.
    Chouikha, Firas
    Fac Med, Sousse, Tunisia.
    Khalifa, Wahbi Belhaj
    Fac Med, Sousse, Tunisia.
    Roa, Camilo C.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Ayuyao, Fernando G.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Tady, Cecil Z.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Tan, Daniel T.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Banal-Yang, Sylvia
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Balanag, Vincent M., Jr.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Reyes, Maria Teresita N.
    Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Dantes, Renato. B.
    Philippine Coll Chest Phys, Manila, Philippines;Philippine Gen Hosp, Lung Ctr Philippines, Nampicuan, Philippines.
    Juvekar, Sanjay
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Hirve, Siddhi
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Sambhudas, Somnath
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Chaidhary, Bharat
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Tambe, Meera
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Pingale, Savita
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Umap, Arati
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Umap, Archana
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Shelar, Nitin
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Devchakke, Sampada
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Chaudhary, Sharda
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Bondre, Suvarna
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Walke, Savita
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Gawhane, Ashleshsa
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Sapkal, Anil
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Argade, Rupali
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Gaikwad, Vijay
    KEM Hosp Res Ctr Pune, Vadu HDSS, Pune, Maharashtra, India.
    Salvi, Sundeep
    Chest Res Fdn, Pune, Maharashtra, India.
    Brashier, Bill
    Chest Res Fdn, Pune, Maharashtra, India.
    Londhe, Jyoti
    Chest Res Fdn, Pune, Maharashtra, India.
    Madas, Sapna
    Chest Res Fdn, Pune, Maharashtra, India.
    Obaseki, Daniel
    Obafemi Awolowo Univ, Ife, Nigeria.
    Erhabor, Gregory
    Obafemi Awolowo Univ, Ife, Nigeria.
    Awopeju, Olayemi
    Obafemi Awolowo Univ, Ife, Nigeria.
    Adewole, Olufemi
    Obafemi Awolowo Univ, Ife, Nigeria.
    COPD: Should Diagnosis Match Physiology?2020In: Chest, ISSN 0012-3692, E-ISSN 1931-3543, Vol. 157, no 2, p. 473-475Article in journal (Other academic)
  • 5.
    Wieslander, Gunilla
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
    Fabjan, Nina
    Vogrincic, Maja
    Kreft, Ivan
    Janson, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Respiratory Medicine and Allergology.
    Spetz-Nyström, Ulrike
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Respiratory Medicine and Allergology.
    Vombergar, Blanka
    Tagesson, Christer
    Leanderson, Per
    Norbäck, Dan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
    Eating Buckwheat Cookies Is Associated with the Reduction in Serum Levels of Myeloperoxidase and Cholesterol: A Double Blind Crossover Study in Day-Care Centre Staffs2011In: Tohoku journal of experimental medicine, ISSN 0040-8727, E-ISSN 1349-3329, Vol. 225, no 2, p. 123-130Article in journal (Refereed)
    Abstract [en]

    Buckwheat food is a good source of antioxidants, e.g. rutin, and other beneficial substances. Here we investigated the effects of the intake of common buckwheat (low rutin content) and tartary buckwheat cookies (high rutin content) on selected clinical markers. A double blind crossover study was performed among female day-care centre staffs (N = 62) from five day-care centres. Participants were randomly divided into two groups. The first group initially consumed four common buckwheat cookies per day (16.5 mg rutin equivalents/day) for two weeks, while the second group consumed four tartary buckwheat cookies per day (359.7 mg rutin equivalents/day). Then the groups switched their type of cookies and consumed them for another two weeks. We monitored selected clinical markers related to cardiovascular disease and lower airway inflammation, lung function, and subjective breathing difficulties in the staffs. Intake of tartary buckwheat cookies reduced the serum level of myeloperoxidase (MPO) by a factor 0.84 (p = 0.02). When grouping the two types of buckwheat cookies together, there was a reduction of total serum cholesterol (p < 0.001) and HDL-cholesterol (p < 0.001) during the study period, with improved lung vital capacity (p < 0.001). The degree of reduction in total and HDL cholesterol levels was similar in staffs with low and high body mass index (cut off 25). In conclusion, intake of tartary buckwheat cookies with high level of the antioxidant rutin may reduce levels of MPO, an indicator of inflammation. Moreover, intake of both types of buckwheat cookies may lower cholesterol levels.

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