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  • 1.
    Juras, Anna
    et al.
    Adam Mickiewicz Univ, Inst Anthropol, Dept Human Evolutionary Biol, Fac Biol, Umultowska 89, PL-61614 Poznan, Poland..
    Chylenski, Maciej
    Adam Mickiewicz Univ, Inst Prehist, Fac Hist, Umultowska 89D, PL-61614 Poznan, Poland..
    Krenz-Niedbala, Marta
    Adam Mickiewicz Univ, Inst Anthropol, Dept Human Evolutionary Biol, Fac Biol, Umultowska 89, PL-61614 Poznan, Poland..
    Malmström, Helena
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för organismbiologi, Evolution och utvecklingsbiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Ehler, Edvard
    Adam Mickiewicz Univ, Inst Anthropol, Dept Human Evolutionary Biol, Fac Biol, Umultowska 89, PL-61614 Poznan, Poland..
    Pospieszny, Lukasz
    Polish Acad Sci, Inst Archaeol & Ethnol, Rubiez 46, PL-61612 Poznan, Poland..
    Lukasik, Sylwia
    Adam Mickiewicz Univ, Inst Anthropol, Dept Human Evolutionary Biol, Fac Biol, Umultowska 89, PL-61614 Poznan, Poland..
    Bednarczyk, Jozef
    Adam Mickiewicz Univ, Inst Prehist, Fac Hist, Umultowska 89D, PL-61614 Poznan, Poland..
    Piontek, Janusz
    Adam Mickiewicz Univ, Inst Anthropol, Dept Human Evolutionary Biol, Fac Biol, Umultowska 89, PL-61614 Poznan, Poland..
    Jakobsson, Mattias
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för organismbiologi, Evolution och utvecklingsbiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Dabert, Miroslawa
    Adam Mickiewicz Univ, Mol Biol Techn Lab, Fac Biol, Umultowska 89, PL-61614 Poznan, Poland..
    Investigating kinship of Neolithic post-LBK human remains from Krusza Zamkowa, Poland using ancient DNA2017Ingår i: Forensic Science International: Genetics, ISSN 1872-4973, E-ISSN 1878-0326, Vol. 26, 30-39 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We applied an interdisciplinary approach to investigate kinship patterns and funerary practices during the middle Neolithic. Genetic studies, radiocarbon dating, and taphonomic analyses were used to examine two grave clusters from Krusza Zamkowa, Poland. To reconstruct kinship and determine biological sex, we extracted DNA from bones and teeth, analyzed mitochondrial genomes and nuclear SNPs using the HID-Ion AmpliSeq (TM) Identity panel generated on Illumina and Ion Torrent platforms, respectively. We further dated the material (AMS C-14) and to exclude aquatic radiocarbon reservoir effects, measures of carbon and nitrogen stable isotopes for diet reconstruction were used. We found distinct mitochondrial genomes belonging to haplogroups U5b2a1a, K1c and H3d in the first grave cluster, and excluded maternal kin patterns among the three analyzed individuals. In the second grave cluster one individual belonged to K1a4. However, we could not affiliate the second individual to a certain haplogroup due to the fragmented state of the mitochondrial genome. Although the individuals from the second grave cluster differ at position 6643, we believe that more data is needed to fully resolve this issue. We retrieved between 26 and 77 autosomal SNPs from three of the individuals. Based on kinship estimations, taking into account the allelic dropout distribution, we could not exclude first degree kin relation between the two individuals from the second grave cluster. We could, however, exclude a first degree kinship between these two individuals and an individual from the first grave cluster. Presumably, not only biological kinship, but also social relations played an important role in the funerary practice during this time period. We further conclude that the HID-Ion AmpliSeq (TM) Identity Panel may prove useful for first degree kin relation studies for samples with good DNA preservation, and that mitochondrial genome capture enrichment is a powerful tool for excluding direct maternal relationship in ancient individuals.

  • 2.
    Lind, Lars
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Kardiovaskulär epidemiologi.
    Ng, Esther
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
    Ingelsson, Erik
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Molekylär epidemiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab. Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.
    Lindgren, Cecilia
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, USA.
    Salihovic, Samira
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Molekylär epidemiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    van Bavel, Bert
    MTM Research Centre, School of Science and Technology, Örebro University, Sweden.
    Mahajan, Anubha
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
    Lampa, Erik
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Kardiovaskulär epidemiologi.
    Morris, Andrew P
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK; Department of Biostatistics, University of Liverpool, Liverpool, UK.
    Lind, P. Monica
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Arbets- och miljömedicin.
    Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p'-dde levels in a population-based sample2017Ingår i: Environment International, ISSN 0160-4120, E-ISSN 1873-6750, Vol. 98, 212-218 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVES: Since the metabolism of the organochlorine pesticide dichlorodiphenyltrichloroethane (DDT) is not fully known in humans, we evaluated if circulating levels of a major breakdown product of DDT, p,p'-DDE, were related to genome-wide genetic and methylation variation in a population-based sample.

    METHODS: In the population-based Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study (1016 subjects all aged 70), circulating levels of p,p'-DDE were analyzed by high-resolution chromatography coupled to high-resolution mass spectrometry (HRGC/HRMS). Genetic variants were genotyped and imputed (1000 Genomes reference, March 2012 release). Methylation sites were assayed using the Illumina HumanMethylation450 array in whole blood. A genome-wide association study (GWAS) approach was applied.

    RESULTS: Evidence for genome-wide significant association with p,p'-DDE levels was observed only for a locus at chromosome 19 corresponding to the CYP2B6 gene (lead SNP rs7260538). Subjects being homozygote for the G allele showed a median level of 472ng/g lipid, while the corresponding level for those being homozygote for the T allele was 192ng/g lipid (p=1.5×10(-31)). An analysis conditioned on the lead SNP disclosed a distinct signal in the same gene (rs7255374, position chr19:41520351; p=2.2×10(-8)). A whole-genome methylation analysis showed one significant relationship vs. p,p'-DDE levels (p=6.2×10(-9)) located 7kb downstream the CYP2B6 gene (cg27089200, position chr19:41531976). This CpG-site was also related to the lead SNP (p=3.8×10(-35)), but mediated only 4% of the effect of the lead SNP on p,p'-DDE levels.

    CONCLUSION: Circulating levels of p,p'-DDE were related to genetic variation in the CYP2B6 gene in the general elderly population. DNA methylation in this gene is not closely linked to the p,p'-DDE levels.

  • 3.
    Grubisic, Lorena M.
    et al.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Bertilsson, Stefan
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Eiler, Alexander
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Heinrich, Friederike
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Brutemark, Andreas
    Tvarminne Zool Stn, Hango, Finland.;Novia Univ Appl Sci, ARONIA Coastal Zone Res Team, Ekenas, Finland.;Abo Akad Univ, Ekenas, Finland..
    Alonso-Sáez, Laura
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Andersson, Anders F.
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. KTH Royal Inst Technol & Sci Life Lab, Sch Biotechnol, Stockholm, Sweden.
    Gantner, Stephan
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab. Leibniz Inst Sci & Math Educ, Dept Educ Sci Biol, Kiel, Germany..
    Riemann, Lasse
    Univ Copenhagen, Dept Biol, Marine Biol Sect, Helsingor, Denmark..
    Beier, Sara
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Leibniz Inst Balt Sea Res Warnemunde IOW, Rostock, Germany..
    Lake bacterioplankton dynamics over diurnal timescales2017Ingår i: Freshwater Biology, ISSN 0046-5070, E-ISSN 1365-2427, Vol. 62, nr 1, 191-204 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    1. Planktonic bacterial community dynamics over short timescales can be of great importance for food webs and ecosystem functioning but are rarely described when microbial community and composition are assessed. To study the significance of such dynamics we sampled the surface water at the deepest point of a mesotrophic lake (Lake Erken, Sweden) every third hour over two days. 2. By combining 454 pyrosequencing of 16S rRNA genes with bromodeoxyuridine immunocapturing of DNA, replicating populations were identified and compared to the community retrieved from total DNA samples. This comparison revealed a significant difference between the actively replicating and total community. 3. The high-frequency diurnal sampling was compared to a year-long survey conducted in the same lake in order to compare the diurnal and seasonal variation in bacterioplankton community composition. At the diurnal-scale, the variation was significantly higher in the replicating than in the total community. However, variation in both active and total diurnal community was significantly lower than the variation in the seasonal total community. 4. Our analysis revealed pronounced short-term dynamics of individual bacterial populations uncoupled from the diurnal light cycle. For example, the proliferating fraction of the most abundant bacterial tribe (LD12) followed a cyclic pattern that covaried with viral abundance. This implies that environmental factors other than light may act as important drivers of microbial community composition, at least in mesotrophic Lake Erken.

  • 4.
    Lind, P. Monica
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Arbets- och miljömedicin.
    Salihovic, Samira
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Molekylär epidemiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab. MTM Research Centre, School of Science and Technology, Örebro University, Örebro, Sweden.
    van Bavel, Bert
    MTM Research Centre, School of Science and Technology, Örebro University, Örebro, Sweden.
    Lind, Lars
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Kardiovaskulär epidemiologi.
    Circulating levels of perfluoroalkyl substances (PFASs) and carotid artery atherosclerosis2017Ingår i: Environmental Research, ISSN 0013-9351, E-ISSN 1096-0953, Vol. 152, 157-164 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND AND OBJECTIVE: During recent years, some persistent organic pollutants (POPs) have been linked to atherosclerosis. One group of POPs, the poly- and perfluoroalkyl substances (PFASs) have not been investigated with regard to atherosclerotic plaques.

    METHODS: Carotid artery atherosclerosis was assessed by ultrasound in 1016 subjects aged 70 years in the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Eight PFASs were detected in >75% of participants' plasma by ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS).

    RESULTS: No significant linear associations were observed between the PFASs and intima-media thickness (IMT), or the echogenicity in the intima-media complex (IM-GSM, a marker of lipid infiltration in the artery) when men and women were analyzed together. Neither was occurrence of carotid plaques related to PFASs levels. However, highly significant interactions were observed between some PFASs and sex regarding both IM-GSM and plaque prevalence. Perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), and perfluoroundecanoic acid (PFUnDA), were all related to IM-GSM in a positive fashion in women (p=0.002-0.003), while these relationships were negative in men. The levels of PFUnDA were significantly related to carotid plaque in women (OR 1.59, 95%CI 1.03-2.43, p=0.03), but not in men (OR 0.93, 95%CI 0.62-1.42, p=0.75).

    CONCLUSIONS: In this cross-sectional study, a pronounced gender difference was observed regarding associations between some PFASs, especially the long-chain PFUnDA, and markers of atherosclerosis, with more pronounced relationships found in women. These findings suggest a sex-specific role for PFASs in atherosclerosis.

  • 5.
    Kühnemund, Malte
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Molekylära verktyg. Uppsala universitet, Science for Life Laboratory, SciLifeLab. Stockholm Univ, Dept Biophys & Biochem, Sci Life Lab, Box 1031, SE-17121 Solna, Sweden..
    Wei, Qingshan
    Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA.;Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA..
    Darai, Evangelia
    Stockholm Univ, Dept Biophys & Biochem, Sci Life Lab, Box 1031, SE-17121 Solna, Sweden..
    Wang, Yingjie
    Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA..
    Hernandez-Neuta, Ivan
    Stockholm Univ, Dept Biophys & Biochem, Sci Life Lab, Box 1031, SE-17121 Solna, Sweden..
    Yang, Zhao
    Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA..
    Tseng, Derek
    Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA..
    Ahlford, Annika
    Stockholm Univ, Dept Biophys & Biochem, Sci Life Lab, Box 1031, SE-17121 Solna, Sweden.;Devyser AB, Instrumentvagen 19, S-12653 Stockholm, Sweden..
    Mathot, Lucy
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Molekylära verktyg. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Sjöblom, Tobias
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Experimentell och klinisk onkologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Ozcan, Aydogan
    Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA.;Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA.;Univ Calif Los Angeles, Calif NanoSyst Inst CNSI, Los Angeles, CA 90095 USA..
    Nilsson, Mats
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Molekylära verktyg. Uppsala universitet, Science for Life Laboratory, SciLifeLab. Stockholm Univ, Dept Biophys & Biochem, Sci Life Lab, Box 1031, SE-17121 Solna, Sweden..
    Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy2017Ingår i: Nature Communications, ISSN 2041-1723, E-ISSN 2041-1723, Vol. 8, 13913Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Molecular diagnostics is typically outsourced to well-equipped centralized laboratories, often far from the patient. We developed molecular assays and portable optical imaging designs that permit on-site diagnostics with a cost-effective mobile-phone-based multimodal microscope. We demonstrate that targeted next-generation DNA sequencing reactions and in situ point mutation detection assays in preserved tumour samples can be imaged and analysed using mobile phone microscopy, achieving a new milestone for tele-medicine technologies.

  • 6.
    Schive, Simen W.
    et al.
    Oslo Univ Hosp, Dept Transplant Med, Inst Canc, Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway..
    Foss, Aksel
    Oslo Univ Hosp, Dept Transplant Med, Inst Canc, Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway..
    Sahraoui, Afaf
    Oslo Univ Hosp, Dept Transplant Med, Inst Canc, Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway..
    Kloster-Jensen, Kristine
    Oslo Univ Hosp, Dept Transplant Med, Inst Canc, Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway..
    Hafsahl, Geir
    Oslo Univ Hosp, Dept Radiol, Inst Canc, Oslo, Norway..
    Kvalheim, Gunnar
    Oslo Univ Hosp, Dept Cell Therapy, Inst Canc, Oslo, Norway..
    Lundgren, Torbjorn
    Karolinska Inst, Div Transplantat Surg, CLINTEC, Stockholm, Sweden..
    von Zur-Mühlen, Bengt
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Transplantationskirurgi.
    Felldin, Marie
    Sahlgrens Univ Hosp, Dept Transplantat, Gothenburg, Sweden..
    Rafael, Ehab
    Univ Hosp, Dept Nephrol & Transplantat, Malmo, Sweden..
    Lempinen, Marko
    Helsinki Univ Hosp, Dept Surg, Helsinki, Finland..
    Korsgren, Olle
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Klinisk immunologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Jenssen, Trond G.
    Oslo Univ Hosp, Dept Transplant Med, Inst Canc, Oslo, Norway.;UiT, Metab & Renal Res Grp, Tromso, Norway..
    Mishra, Vinod
    Oslo Univ Hosp, Dept Finance, Oslo, Norway.;Oslo Univ Hosp, Resource Management Unit, Oslo, Norway..
    Scholz, Hanne
    Oslo Univ Hosp, Dept Transplant Med, Inst Canc, Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway..
    Cost and clinical outcome of islet transplantation in Norway 2010-20152017Ingår i: Clinical Transplantation, ISSN 0902-0063, E-ISSN 1399-0012, Vol. 31, nr 1Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Islet transplantation is a minimally invasive -cell replacement strategy. Islet transplantation is a reimbursed treatment in Norway. Here, we summarize the cost and clinical outcome of 31 islet transplantations performed at Oslo University Hospital (OUS) from January 2010 to June 2015. Patients were retrospectively divided into three groups. Thirteen patients received either one or two islet transplantation alone (ITA), while five patients received islet transplantation after previous solid organ transplantation. For the group receiving 2 ITA, Kaplan-Meier estimates show an insulin independence of 20% more than 4years after their last transplantation. An estimated 70% maintain at least partial graft function, defined as fasting C-peptide >0.1nmolL(-1), and 47% maintain a HbA1c below 6.5% or 2 percent points lower than before ITA. For all groups combined, we estimate that 44% of the patients have a 50% reduction in insulin requirement 4years after the initial islet transplantation. The average cost for an islet transplantation procedure was 347297 +/- 60588NOK, or 35424 +/- 6182EUR, of which isolation expenses represent 34%. We hereby add to the common pool of growing experience with islet transplantation and also describe the cost of the treatment at our center.

  • 7.
    Hibar, Derrek P.
    et al.
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA..
    Adams, Hieab H. H.
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands.;Erasmus MC, Dept Radiol & Nucl Med, NL-3015 CE Rotterdam, Netherlands..
    Jahanshad, Neda
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA..
    Chauhan, Ganesh
    Univ Bordeaux, INSERM Unit U1219, F-33076 Bordeaux, France..
    Stein, Jason L.
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA.;UNC, Dept Genet, Chapel Hill, NC 27599 USA.;UNC, UNC Neurosci Ctr, Chapel Hill, NC 27599 USA..
    Hofer, Edith
    Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Auenbruggerpl 22, A-8036 Graz, Austria.;Med Univ Graz, Inst Med Informat Stat & Documentat, Auenbruggerpl 22, A-8036 Graz, Austria..
    Renteria, Miguel E.
    QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia..
    Bis, Joshua C.
    Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, 1730 Minor Ave Suite 1360, Seattle, WA 98101 USA..
    Arias-Vasquez, Alejandro
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Med Ctr, Dept Psychiat, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Med Ctr, Dept Cognit Neurosci, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Ikram, M. Kamran
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands.;Duke NUS Grad Med Sch, Acad Med Res Inst, Singapore 169857, Singapore.;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore 168751, Singapore.;Natl Univ Hlth Syst, MACC, Singapore 119228, Singapore.;Natl Univ Singapore, Dept Pharmacol, Singapore 119077, Singapore..
    Desrivieres, Sylvane
    Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London SE5 8AF, England..
    Vernooij, Meike W.
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands.;Erasmus MC, Dept Radiol & Nucl Med, NL-3015 CE Rotterdam, Netherlands..
    Abramovic, Lucija
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    Alhusaini, Saud
    McGill Univ, Dept Neurol & Neurosurg, Montreal Neurol Inst, Montreal, PQ H3A 2B4, Canada.;Royal Coll Surgeons Ireland, 123 St Stephens Green, Dublin 2, Ireland..
    Amin, Najaf
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands..
    Andersson, Micael
    Umea Univ, Dept Integrat Med Biol, S-90187 Umea, Sweden.;Umea Univ, Umea Ctr Funct Brain Imaging, S-90187 Umea, Sweden..
    Arfanakis, Konstantinos
    IIT, Dept Biomed Engn, Chicago, IL 60612 USA.;Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA.;Rush Univ, Med Ctr, Dept Diagnost Radiol & Nucl Med, Chicago, IL 60616 USA..
    Aribisala, Benjamin S.
    Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh EH4 2XU, Midlothian, Scotland.;Lagos State Univ, Dept Comp Sci, PMB 01 LASU, Lagos, Nigeria.;Univ Edinburgh, Dept Neuroimaging Sci, Scottish Imaging Network, Platform Sci Excellence SINAPSE Collaborat, Edinburgh EH16 4SB, Midlothian, Scotland..
    Armstrong, Nicola J.
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia.;Murdoch Univ, Math & Stat, Perth, WA 6150, Australia..
    Athanasiu, Lavinia
    Univ Oslo, NORMENT KG Jebsen Ctr, Inst Clin Med, N-0315 Oslo, Norway.;Oslo Univ Hosp, NORMENT KG Jebsen Ctr, Div Mental Hlth & Addict, N-0424 Oslo, Norway..
    Axelsson, Tomas
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Molekylär medicin. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Beecham, Ashley H.
    Univ Miami, Miller Sch Med, Dr John T Macdonald Fdn Dept Human Genet, Miami, FL 33136 USA.;Univ Miami, Miller Sch Med, John P Hussman Inst Human Gen, Miami, FL 33136 USA..
    Beiser, Alexa
    Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA.;Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02118 USA.;Framingham Heart Dis Epidemiol Study, 17 Mt Wayte Ave, Framingham, MA 01703 USA..
    Bernard, Manon
    Univ Toronto, Hosp Sick Children, Toronto, ON M5G 1X8, Canada..
    Blanton, Susan H.
    Univ Miami, Miller Sch Med, Dr John T Macdonald Fdn Dept Human Genet, Miami, FL 33136 USA.;Univ Miami, Miller Sch Med, John P Hussman Inst Human Gen, Miami, FL 33136 USA..
    Bohlken, Marc M.
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    Boks, Marco P.
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    Bralten, Janita
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Brickman, Adam M.
    Columbia Univ, Med Ctr, Taub Inst Res Alzheimers Dis & Aging Brain, 639 West 1168th St, New York, NY 10032 USA.;Columbia Univ, Med Ctr, GH Sergievsky Ctr, 639 West 1168th St, New York, NY 10032 USA.;Columbia Univ, Med Ctr, Dept Neurol, 639 West 1168th St, New York, NY 10032 USA..
    Carmichael, Owen
    Pennington Biomed Res Ctr, 6400 Perkins Rd, Baton Rouge, LA 70808 USA..
    Chakravarty, M. Mallar
    Douglas Mental Hlth Univ Inst, Cerebral Imaging Ctr, Montreal, PQ H4H 1R3, Canada.;McGill Univ, Dept Psychiat & Biomed Engn, Montreal, PQ H3A 2B4, Canada..
    Chen, Qiang
    Lieber Inst Brain Dev, Baltimore, MD 21205 USA..
    Ching, Christopher R. K.
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA.;Univ Calif Los Angeles, Sch Med, Interdept Neurosci Grad Program, Los Angeles, CA 90095 USA..
    Chouraki, Vincent
    Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA.;Framingham Heart Dis Epidemiol Study, 17 Mt Wayte Ave, Framingham, MA 01703 USA.;Univ Lille, CHU Lille, INSERM, Inst Pasteur Lille,RID AGE Risk Factors & Mol Det, F-59000 Lille, France..
    Cuellar-Partida, Gabriel
    QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia..
    Crivello, Fabrice
    Univ Bordeaux, IMN UMR5293, GIN, CNRS,CEA, 146 Rue Leo Saignat, F-33076 Bordeaux, France..
    Den Braber, Anouk
    Vrije Univ Amsterdam, Biol Psychol, Amsterdam Neurosci, NL-1081 BT Amsterdam, Netherlands.;Vrije Univ Amsterdam, Med Ctr, NL-1081 BT Amsterdam, Netherlands..
    Doan, Nhat Trung
    Ehrlich, Stefan
    Tech Univ Dresden, Fac Med, Div Psychol & Social Med & Dev Neurosci, D-01307 Dresden, Germany.;Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Martinos Ctr Biomed Imaging, Charlestown, MA 02129 USA..
    Giddaluru, Sudheer
    Univ Bergen, Dept Clin Sci, NORMENT KG Jebsen Ctr Psychosis Res, N-5021 Bergen, Norway.;Haukeland Hosp, Dr Einar Martens Res Grp Biol Psychiat, Ctr Med Genet & Mol Med, N-5021 Bergen, Norway..
    Goldman, Aaron L.
    Lieber Inst Brain Dev, Baltimore, MD 21205 USA..
    Gottesman, Rebecca F.
    Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21287 USA..
    Grimm, Oliver
    Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Dept Data Sci, D-68159 Mannheim, Germany..
    Griswold, Michael E.
    Univ Mississippi, Med Ctr, Dept Data Sci, Jackson, MS 39216 USA..
    Guadalupe, Tulio
    Max Planck Inst Psycholinguist, Language & Genet Dept, NL-6525 XD Nijmegen, Netherlands.;Int Max Planck Res Sch Language Sci, NL-6525 XD Nijmegen, Netherlands..
    Gutman, Boris A.
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA..
    Hass, Johanna
    Tech Univ Dresden, Fac Med, Dept Child & Adolescent Psychiat, D-01307 Dresden, Germany..
    Haukvik, Unn K.
    Univ Oslo, NORMENT KG Jebsen Ctr, Inst Clin Med, N-0315 Oslo, Norway.;Diakonhjemmet Hosp, Dept Res & Dev, N-0319 Oslo, Norway..
    Hoehn, David
    Max Planck Inst Psychiat, D-80804 Munich, Germany..
    Holmes, Avram J.
    Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA.;Yale Univ, Dept Psychol, New Haven, CT 06520 USA..
    Hoogman, Martine
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Janowitz, Deborah
    Univ Med Greifswald, Dept Psychiat, D-17489 Greifswald, Germany..
    Jia, Tianye
    Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London SE5 8AF, England..
    Jorgensen, Kjetil N.
    Univ Oslo, NORMENT KG Jebsen Ctr, Inst Clin Med, N-0315 Oslo, Norway.;Diakonhjemmet Hosp, Dept Res & Dev, N-0319 Oslo, Norway..
    Karbalai, Nazanin
    Max Planck Inst Psychiat, D-80804 Munich, Germany..
    Kasperaviciute, Dalia
    UCL Inst Neurol, London, England.;Epilepsy Soc, St Peter, Bucks, England.;Imperial Coll London, Dept Med, London SW7 2AZ, England..
    Kim, Sungeun
    Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Ctr Computat Biol & Bioinformat, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA..
    Klein, Marieke
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Kraemer, Bernd
    Heidelberg Univ, Dept Gen Psychiat, Sect Expt Psychopathol & Neuroimaging, D-69120 Heidelberg, Germany..
    Lee, Phil H.
    Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Stanley Ctr Psychiat Res, Boston, MA 02141 USA.;Harvard Med Sch, Massachusetts Gen Hosp, Lurie Ctr Autism, Lexington, MA 02421 USA..
    Liewald, David C. M.
    Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland..
    Lopez, Lorna M.
    Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland..
    Luciano, Michelle
    Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland..
    Macare, Christine
    Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London SE5 8AF, England..
    Marquand, Andre F.
    Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Ctr Cognit Neuroimaging, NL-6525 EN Nijmegen, Netherlands..
    Matarin, Mar
    UCL Inst Neurol, London, England.;Epilepsy Soc, St Peter, Bucks, England.;UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England..
    Mather, Karen A.
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia..
    Mattheisen, Manuel
    Aarhus Univ, Dept Biomed, DK-8000 Aarhus, Denmark.;iPSYCH, Lundbeck Fdn Initiat Integrat Psychiat Res, DK-8000 Aarhus, Denmark.;iPSYCH, Lundbeck Fdn Initiat Integrat Psychiat Res, DK-8000 Copenhagen, Denmark.;Aarhus Univ, iSEQ, Ctr Integrated Sequencing, DK-8000 Aarhus, Denmark..
    McKay, David R.
    Yale Univ, Dept Psychiat, New Haven, CT 06511 USA.;Olin Neuropsychiat Res Ctr, Hartford, CT 06114 USA..
    Milaneschi, Yuri
    VU Univ Med Ctr GGZ inGeest, Dept Psychiat, EMGO Inst Hlth & Care Res, NL-1081 HL Amsterdam, Netherlands.;VU Univ Med Ctr GGZ inGeest, Neurosci Campus Amsterdam, NL-1081 HL Amsterdam, Netherlands..
    Maniega, Susana Munoz
    Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh EH4 2XU, Midlothian, Scotland.;Univ Edinburgh, Dept Neuroimaging Sci, Scottish Imaging Network, Platform Sci Excellence SINAPSE Collaborat, Edinburgh EH16 4SB, Midlothian, Scotland.;Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland..
    Nho, Kwangsik
    Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Ctr Computat Biol & Bioinformat, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA..
    Nugent, Allison C.
    NIMH, Human Genet Branch, Intramural Res Program, 35 Convent Dr,Rm 1A202, Bethesda, MD 20892 USA..
    Nyquist, Paul
    Johns Hopkins, Dept Neurol, Dept Anesthesia Crit Care Med, Dept Neurosurg, USA600 N Wolfe St, Baltimore, MD 21287 USA..
    Loohuis, Loes M. Olde
    Univ Calif Los Angeles, Ctr Neurobehav Genet, Los Angeles, CA 90095 USA..
    Oosterlaan, Jaap
    Vrije Univ Amsterdam, Dept Clin Neuropsychol, NL-1081 HV Amsterdam, Netherlands..
    Papmeyer, Martina
    Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh EH10 5HF, Midlothian, Scotland.;Univ Bern, Univ Hosp Psychiat, Div Syst Neurosci Psychopathol, Translat Res Ctr, CH-3060 Bern, Switzerland..
    Pirpamer, Lukas
    Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Auenbruggerpl 22, A-8036 Graz, Austria..
    Puetz, Benno
    Max Planck Inst Psychiat, D-80804 Munich, Germany..
    Ramasamy, Adaikalavan
    UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England.;Kings Coll London, Dept Med & Mol Genet, London SE1 9RT, England.;Univ Oxford, Jenner Inst Labs, Oxford OX3 7DQ, England..
    Richards, Jennifer S.
    Radboud Univ Nijmegen, Med Ctr, Dept Cognit Neurosci, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Karakter Child & Adolescent Psychiat Univ Ctr, NL-6525 GC Nijmegen, Netherlands..
    Risacher, Shannon L.
    Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA..
    Roiz-Santianez, Roberto
    Univ Cantabria IDIVAL, Dept Med & Psychiat, Univ Hosp Marques Valdecilla, Sch Med, Santander 39008, Spain.;CIBERSAM Ctr Invest Biomed Red Salud Mental, Santander 39011, Spain..
    Rommelse, Nanda
    Radboud Univ Nijmegen, Med Ctr, Dept Psychiat, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Karakter Child & Adolescent Psychiat Univ Ctr, NL-6525 GC Nijmegen, Netherlands..
    Ropele, Stefan
    Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Auenbruggerpl 22, A-8036 Graz, Austria..
    Rose, Emma J.
    Trinity Coll Dublin, Psychosis Res Grp, Dept Psychiat, Dublin 2, Ireland.;Trinity Coll Dublin, Trinity Translat Med Inst, Dublin 2, Ireland..
    Royle, Natalie A.
    Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh EH4 2XU, Midlothian, Scotland.;Univ Edinburgh, Dept Neuroimaging Sci, Scottish Imaging Network, Platform Sci Excellence SINAPSE Collaborat, Edinburgh EH16 4SB, Midlothian, Scotland.;Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh EH16 4SB, Midlothian, Scotland..
    Rundek, Tatjana
    Univ Miami, Miller Sch Med, Dept Neurol, Miami, FL 33136 USA.;Univ Miami, Miller Sch Med, Dept Epidemiol & Publ Hlth Sci, Miami, FL 33136 USA..
    Saemann, Philipp G.
    Max Planck Inst Psychiat, D-80804 Munich, Germany..
    Saremi, Arvin
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA..
    Satizabal, Claudia L.
    Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA.;Framingham Heart Dis Epidemiol Study, 17 Mt Wayte Ave, Framingham, MA 01703 USA..
    Schmaal, Lianne
    Orygen, Natl Ctr Excellence Youth Mental Hlth, Melbourne, Vic 3502, Australia.;Univ Melbourne, Ctr Youth Mental Hlth, Melbourne, Vic 3502, Australia.;Vrije Univ Amsterdam, Med Ctr, Dept Psychiat, Neurosci Campus Amsterdam, NL-1007 MB Amsterdam, Netherlands..
    Schork, Andrew J.
    Univ Calif San Diego, Multimodal Imaging Lab, Dept Neurosci, San Diego, CA 92093 USA.;Univ Calif San Diego, Dept Cognit Sci, San Diego, CA 92161 USA..
    Shen, Li
    Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Ctr Computat Biol & Bioinformat, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA..
    Shin, Jean
    Univ Toronto, Hosp Sick Children, Toronto, ON M5G 1X8, Canada..
    Shumskaya, Elena
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Ctr Cognit Neuroimaging, NL-6525 EN Nijmegen, Netherlands..
    Smith, Albert V.
    Iceland Heart Assoc, IS-201 Kopavogur, Iceland.;Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland..
    Sprooten, Emma
    Yale Univ, Dept Psychiat, New Haven, CT 06511 USA.;Olin Neuropsychiat Res Ctr, Hartford, CT 06114 USA.;Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA..
    Strike, Lachlan T.
    QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia.;Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia..
    Teumer, Alexander
    Univ Med Greifswald, Inst Community Med, D-17489 Greifswald, Germany..
    Tordesillas-Gutierrez, Diana
    CIBERSAM Ctr Invest Biomed Red Salud Mental, Santander 39011, Spain.;Valdecilla Biomed Res Inst IDIVAL, Neuroimaging Unit, Technol Facilities, Santander 39011, Cantabria, Spain..
    Toro, Roberto
    Inst Pasteur, F-75015 Paris, France..
    Trabzuni, Daniah
    UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England.;King Faisal Specialist Hosp & Res Ctr, Dept Genet, Riyadh 11211, Saudi Arabia..
    Trompet, Stella
    Leiden Univ, Med Ctr, Dept Cardiol, NL-2300 RC Leiden, Netherlands..
    Vaidya, Dhananjay
    Johns Hopkins Univ, Sch Med, Dept Med, GeneSTAR Res Ctr, 1830 Monument St Suite 8028, Baltimore, MD 21287 USA..
    Van der Grond, Jeroen
    Leiden Univ, Med Ctr, Dept Radiol, NL-2300 RC Leiden, Netherlands..
    Van der Lee, Sven J.
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands..
    Van der Meer, Dennis
    Univ Groningen, Dept Psychiat, Univ Med Ctr Groningen, NL-9700 RB Groningen, Netherlands..
    Van Donkelaar, Marjolein M. J.
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Van Eijk, Kristel R.
    UMC Utrecht, Brain Ctr Rudolf Magnus, Human Neurogenet Unit, NL-3584 CG Utrecht, Netherlands..
    Van Erp, Theo G. M.
    Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA 92617 USA..
    Van Rooij, Daan
    Radboud Univ Nijmegen, Med Ctr, Dept Cognit Neurosci, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Univ Groningen, Dept Psychiat, Univ Med Ctr Groningen, NL-9700 RB Groningen, Netherlands..
    Walton, Esther
    Tech Univ Dresden, Fac Med, Div Psychol & Social Med & Dev Neurosci, D-01307 Dresden, Germany.;Georgia State Univ, Dept Psychol, Atlanta, GA 30302 USA..
    Westlye, Lars T.
    Oslo Univ Hosp, NORMENT KG Jebsen Ctr, Div Mental Hlth & Addict, N-0424 Oslo, Norway.;Georgia State Univ, Dept Psychol, Atlanta, GA 30302 USA..
    Whelan, Christopher D.
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA.;Royal Coll Surgeons Ireland, 123 St Stephens Green, Dublin 2, Ireland..
    Windham, Beverly G.
    Univ Oslo, Dept Psychol, NORMENT KG Jebsen Ctr, N-0317 Oslo, Norway..
    Winkler, Anderson M.
    Yale Univ, Dept Psychiat, New Haven, CT 06511 USA.;Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA..
    Wittfeld, Katharina
    Univ Med Greifswald, Dept Psychiat, D-17489 Greifswald, Germany.;Univ Oxford, FMRIB Ctr, Oxford OX3 9DU, England..
    Woldehawariat, Girma
    NIMH, Human Genet Branch, Intramural Res Program, 35 Convent Dr,Rm 1A202, Bethesda, MD 20892 USA..
    Wolf, Christiane
    German Ctr Neurodegenerat Dis DZNE Rostock Greifs, D-17487 Greifswald, Germany..
    Wolfers, Thomas
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Yanek, Lisa R.
    Johns Hopkins Univ, Sch Med, Dept Med, GeneSTAR Res Ctr, 1830 Monument St Suite 8028, Baltimore, MD 21287 USA..
    Yang, Jingyun
    Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA.;Univ Wurzburg, Dept Psychiat Psychosomat & Psychotherapy, D-97080 Wurzburg, Germany..
    Zijdenbos, Alex
    Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA..
    Zwiers, Marcel P.
    Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Ctr Cognit Neuroimaging, NL-6525 EN Nijmegen, Netherlands..
    Agartz, Ingrid
    Univ Oslo, NORMENT KG Jebsen Ctr, Inst Clin Med, N-0315 Oslo, Norway.;Diakonhjemmet Hosp, Dept Res & Dev, N-0319 Oslo, Norway.;Biospective Inc, 6100 Ave Royalmount, Montreal, PQ H4P 2R2, Canada..
    Almasy, Laura
    Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17177 Stockholm, Sweden.;Univ Texas Brownsville, Rio Grande Valley Sch Med, South Texas Diabet & Obes Inst, Brownsville, TX 78250 USA.;Univ Texas, Rio Grande Valley Sch Med, South Texas Diabet & Obes Inst, Edinburg, TX 78250 USA.;Univ Texas San Antonio, Rio Grande Valley Sch Med, South Texas Diabet & Obes Inst, San Antonio, TX 78250 USA.;Univ Penn, Dept Genet, Perelman Sch Med, Philadelphia, PA 19104 USA..
    Ames, David
    Childrens Hosp Philadelphia, Dept Biomed & Hlth Informat, Philadelphia, PA 19104 USA.;Royal Melbourne Hosp, Natl Ageing Res Inst, Parkville, Vic 3052, Australia..
    Amouyel, Philippe
    Univ Lille, CHU Lille, INSERM, Inst Pasteur Lille,RID AGE Risk Factors & Mol Det, F-59000 Lille, France..
    Andreassen, Ole A.
    Univ Oslo, NORMENT KG Jebsen Ctr, Inst Clin Med, N-0315 Oslo, Norway.;Oslo Univ Hosp, NORMENT KG Jebsen Ctr, Div Mental Hlth & Addict, N-0424 Oslo, Norway..
    Arepalli, Sampath
    Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic 3101, Australia..
    Assareh, Amelia A.
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia..
    Barral, Sandra
    Columbia Univ, Med Ctr, Taub Inst Res Alzheimers Dis & Aging Brain, 639 West 1168th St, New York, NY 10032 USA.;Columbia Univ, Med Ctr, GH Sergievsky Ctr, 639 West 1168th St, New York, NY 10032 USA.;Columbia Univ, Med Ctr, Dept Neurol, 639 West 1168th St, New York, NY 10032 USA..
    Bastin, Mark E.
    Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh EH4 2XU, Midlothian, Scotland.;Univ Edinburgh, Dept Neuroimaging Sci, Scottish Imaging Network, Platform Sci Excellence SINAPSE Collaborat, Edinburgh EH16 4SB, Midlothian, Scotland.;Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh EH16 4SB, Midlothian, Scotland..
    Becker, Diane M.
    Johns Hopkins Univ, Sch Med, Dept Med, GeneSTAR Res Ctr, 1830 Monument St Suite 8028, Baltimore, MD 21287 USA..
    Becker, James T.
    NIA, Neurogenet Lab, NIH, Bethesda, MD 20892 USA..
    Bennett, David A.
    Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA.;Univ Wurzburg, Dept Psychiat Psychosomat & Psychotherapy, D-97080 Wurzburg, Germany..
    Blangero, John
    Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17177 Stockholm, Sweden..
    van Bokhoven, Hans
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Boomsma, Dorret I.
    Vrije Univ Amsterdam, Biol Psychol, Amsterdam Neurosci, NL-1081 BT Amsterdam, Netherlands.;Vrije Univ Amsterdam, Med Ctr, NL-1081 BT Amsterdam, Netherlands..
    Brodaty, Henry
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia.;Univ Pittsburgh, Dept Psychiat, 3501 Forbes Ave,Suite 830, Pittsburgh, PA 15213 USA.;Univ Pittsburgh, Dept Neurol, 3501 Forbes Ave,Suite 830, Pittsburgh, PA 15213 USA.;Univ Pittsburgh, Dept Psychol, 3501 Forbes Ave,Suite 830, Pittsburgh, PA 15213 USA..
    Brouwer, Rachel M.
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    Brunner, Han G.
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Univ New South Wales, Dementia Collaborat Res Centre Assessment & Bette, Sydney, NSW 2052, Australia..
    Buckner, Randy L.
    Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA.;Maastricht Univ, Med Ctr, Dept Clin Genet, NL-6200 MD Maastricht, Netherlands.;Maastricht Univ, Med Ctr, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands..
    Buitelaar, Jan K.
    Radboud Univ Nijmegen, Med Ctr, Dept Cognit Neurosci, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Karakter Child & Adolescent Psychiat Univ Ctr, NL-6525 GC Nijmegen, Netherlands..
    Bulayeva, Kazima B.
    Harvard Univ, Dept Psychol, Ctr Brain Sci, Cambridge, MA 02138 USA..
    Cahn, Wiepke
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    Calhoun, Vince D.
    Dagestan State Univ, Dept Evolut & Genet, Makhachkala 367000, Dagestan, Russia.;Mind Res Network, Albuquerque, NM 87106 USA.;LBERI, Albuquerque, NM 87106 USA..
    Cannon, Dara M.
    NIMH, Human Genet Branch, Intramural Res Program, 35 Convent Dr,Rm 1A202, Bethesda, MD 20892 USA.;Univ New Mexico, Dept ECE, Albuquerque, NM 87131 USA..
    Cavalleri, Gianpiero L.
    Royal Coll Surgeons Ireland, 123 St Stephens Green, Dublin 2, Ireland..
    Cheng, Ching-Yu
    Duke NUS Grad Med Sch, Acad Med Res Inst, Singapore 169857, Singapore.;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore 168751, Singapore.;Natl Univ Ireland Galway, Ctr Neuroimaging & Cognit Genom NICOG, Clin Neuroimaging Lab, NCBES Galway Neurosci Ctr,Coll Med Nursing & Hlth, Galway H91 TK33, Ireland..
    Cichon, Sven
    Natl Univ Singapore, Dept Ophthalmol, Yong Loo Lin Sch Med, Singapore 119077, Singapore.;Univ Basel, Dept Biome, Div Med Genet, CH-4031 Basel, Switzerland.;Univ Bonn, Inst Human Genet, D-53127 Bonn, Germany..
    Cookson, Mark R.
    Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic 3101, Australia..
    Corvin, Aiden
    Trinity Coll Dublin, Psychosis Res Grp, Dept Psychiat, Dublin 2, Ireland.;Trinity Coll Dublin, Trinity Translat Med Inst, Dublin 2, Ireland..
    Crespo-Facorro, Benedicto
    Univ Cantabria IDIVAL, Dept Med & Psychiat, Univ Hosp Marques Valdecilla, Sch Med, Santander 39008, Spain.;CIBERSAM Ctr Invest Biomed Red Salud Mental, Santander 39011, Spain..
    Curran, Joanne E.
    Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17177 Stockholm, Sweden..
    Czisch, Michael
    Max Planck Inst Psychiat, D-80804 Munich, Germany..
    Dale, Anders M.
    Res Ctr Julich, Inst Neurosci & Med INM 1, D-52425 Julich, Germany.;Univ Calif San Diego, Ctr Multimodal Imaging & Genet, San Diego, CA 92093 USA..
    Davies, Gareth E.
    Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA.;Univ Calif San Diego, Dept Radiol, La Jolla, CA 92093 USA.;Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA.;Univ Calif San Diego, Dept Cognit Sci, La Jolla, CA 92093 USA..
    De Craen, Anton J. M.
    Avera Inst Human Genet, Sioux Falls, SD 57108 USA..
    De Geus, Eco J. C.
    Vrije Univ Amsterdam, Biol Psychol, Amsterdam Neurosci, NL-1081 BT Amsterdam, Netherlands.;Vrije Univ Amsterdam, Med Ctr, NL-1081 BT Amsterdam, Netherlands..
    De Jager, Philip L.
    Natl Univ Singapore, Dept Pharmacol, Singapore 119077, Singapore.;Harvard Med Sch, Boston, MA 02115 USA.;Leiden Univ, Med Ctr, Dept Gerontol & Geriatr, NL-2300 RC Leiden, Netherlands.;Brigham & Womens Hosp, Program Translat NeuroPsychiat Gen, Dept Neurol, Boston, MA 02115 USA.;Brigham & Womens Hosp, Program Translat NeuroPsychiat Gen, Dept Psychiat, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA..
    De Zubicaray, Greig I.
    Broad Inst, Cambridge, MA 02142 USA..
    Deary, Ian J.
    Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland..
    Debette, Stephanie
    Univ Bordeaux, INSERM Unit U1219, F-33076 Bordeaux, France.;Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA.;Queensland Univ Technol, Fac Hlth & Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia..
    DeCarli, Charles
    Bordeaux Univ Hosp, Dept Neurol, F-33076 Bordeaux, France..
    Delanty, Norman
    Royal Coll Surgeons Ireland, 123 St Stephens Green, Dublin 2, Ireland.;Univ Calif Davis, Imaging Dementia & Aging IDeA Lab, Dept Neurol, 4860 Y St,Suite 3700, Sacramento, CA 95817 USA.;Univ Calif Davis, Ctr Neurosci, 4860 Y St,Suite 3700, Sacramento, CA 95817 USA..
    Depondt, Chantal
    Beaumont Hosp, Div Neurol, Dublin 9, Ireland..
    DeStefano, Anita
    Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02118 USA.;Framingham Heart Dis Epidemiol Study, 17 Mt Wayte Ave, Framingham, MA 01703 USA..
    Dillman, Allissa
    Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic 3101, Australia..
    Djurovic, Srdjan
    Univ Bergen, Dept Clin Sci, NORMENT KG Jebsen Ctr Psychosis Res, N-5021 Bergen, Norway.;Univ Libre Bruxelles, Dept Neurol, Hop Erasme, B-1070 Brussels, Belgium..
    Donohoe, Gary
    Oslo Univ Hosp, Dept Med Genet, N-0420 Oslo, Norway.;Natl Univ Ireland Galway, Cognit Genet & Cognit Therapy Grp, Neuroimaging Cognit & Genom Ctr NICOG, Sch Psychol & Discipline Biochem, Galway H91 TK33, Ireland.;Natl Univ Ireland Galway, Sch Psychol & Discipline Biochem, NCBES Galway Neurosci Ctr, Galway H91 TK33, Ireland..
    Drevets, Wayne C.
    NIMH, Human Genet Branch, Intramural Res Program, 35 Convent Dr,Rm 1A202, Bethesda, MD 20892 USA.;Trinity Coll Dublin, Neuropsychiat Genet Res Grp, Dept Psychiat, Dublin 8, Ireland.;Trinity Coll Dublin, Trinity Coll, Inst Psychiat, Dublin 8, Ireland..
    Duggirala, Ravi
    Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17177 Stockholm, Sweden..
    Dyer, Thomas D.
    Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17177 Stockholm, Sweden..
    Enzinger, Christian
    Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Auenbruggerpl 22, A-8036 Graz, Austria..
    Erk, Susanne
    Janssen Res & Dev LLC, Titusville, NJ 08560 USA..
    Espeseth, Thomas
    Oslo Univ Hosp, NORMENT KG Jebsen Ctr, Div Mental Hlth & Addict, N-0424 Oslo, Norway.;Georgia State Univ, Dept Psychol, Atlanta, GA 30302 USA..
    Fedko, Iryna O.
    Vrije Univ Amsterdam, Biol Psychol, Amsterdam Neurosci, NL-1081 BT Amsterdam, Netherlands.;Vrije Univ Amsterdam, Med Ctr, NL-1081 BT Amsterdam, Netherlands..
    Fernandez, Guillen
    Radboud Univ Nijmegen, Med Ctr, Dept Cognit Neurosci, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Ferrucci, Luigi
    Charite, Dept Psychiat & Psychotherapy, Campus Charite Mitte,Charite Pl 1, D-10117 Berlin, Germany..
    Fisher, Simon E.
    Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Max Planck Inst Psycholinguist, Language & Genet Dept, NL-6525 XD Nijmegen, Netherlands..
    Fleischman, Debra A.
    Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA.;NIA, Intramural Res Program, Baltimore, MD 21224 USA..
    Ford, Ian
    Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60616 USA.;Rush Univ, Med Ctr, Dept Behav Sci, Chicago, IL 60616 USA..
    Fornage, Myriam
    Univ Glasgow, Robertson Ctr Biostat, Glasgow G41 4DQ, Lanark, Scotland..
    Foroud, Tatiana M.
    Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA.;Univ Texas Hlth Sci Ctr Houston, Inst Mol Med & Human Genet Ctr, Houston, TX 77030 USA..
    Fox, Peter T.
    Indiana Univ Sch Med, Med & Mol Genet, Indianapolis, IN 46202 USA..
    Francks, Clyde
    Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands.;Max Planck Inst Psycholinguist, Language & Genet Dept, NL-6525 XD Nijmegen, Netherlands..
    Fukunaga, Masaki
    Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA..
    Gibbs, J. Raphael
    UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England.;Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic 3101, Australia..
    Glahn, David C.
    Yale Univ, Dept Psychiat, New Haven, CT 06511 USA.;Olin Neuropsychiat Res Ctr, Hartford, CT 06114 USA..
    Gollub, Randy L.
    Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Martinos Ctr Biomed Imaging, Charlestown, MA 02129 USA.;Harvard Med Sch, Boston, MA 02115 USA..
    Goring, Harald H. H.
    Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17177 Stockholm, Sweden..
    Green, Robert C.
    Harvard Med Sch, Boston, MA 02115 USA.;Natl Inst Physiol Sci, Div Cerebral Integrat, Okazaki, Aichi 4448585, Japan..
    Gruber, Oliver
    Heidelberg Univ, Dept Gen Psychiat, Sect Expt Psychopathol & Neuroimaging, D-69120 Heidelberg, Germany..
    Gudnason, Vilmundur
    Iceland Heart Assoc, IS-201 Kopavogur, Iceland.;Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland..
    Guelfi, Sebastian
    UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England..
    Haberg, Asta K.
    Brigham & Womens Hosp, Dept Med, Div Genet, 75 Francis St, Boston, MA 02115 USA.;Norwegian Univ Sci & Technol NTNU, Fac Med, Dept Neurosci, N-7491 Trondheim, Norway..
    Hansell, Narelle K.
    QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia.;Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia..
    Hardy, John
    UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England..
    Hartman, Catharina A.
    Univ Groningen, Dept Psychiat, Univ Med Ctr Groningen, NL-9700 RB Groningen, Netherlands..
    Hashimoto, Ryota
    Univ Trondheim Hosp, Dept Radiol, St Olavs Hosp, N-7030 Trondheim, Norway.;Osaka Univ, Dept Psychiat, Grad Sch Med, Suita, Osaka 5650871, Japan..
    Hegenscheid, Katrin
    Osaka Univ, Mol Res Ctr Childrens Mental Dev, United Grad Sch Child Dev, Suita, Osaka 5650871, Japan..
    Heinz, Andreas
    Janssen Res & Dev LLC, Titusville, NJ 08560 USA..
    Le Hellard, Stephanie
    Univ Bergen, Dept Clin Sci, NORMENT KG Jebsen Ctr Psychosis Res, N-5021 Bergen, Norway.;Haukeland Hosp, Dr Einar Martens Res Grp Biol Psychiat, Ctr Med Genet & Mol Med, N-5021 Bergen, Norway..
    Hernandez, Dena G.
    Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh EH4 2XU, Midlothian, Scotland.;Univ Edinburgh, Dept Neuroimaging Sci, Scottish Imaging Network, Platform Sci Excellence SINAPSE Collaborat, Edinburgh EH16 4SB, Midlothian, Scotland.;Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland.;UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England.;Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh EH16 4SB, Midlothian, Scotland.;Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic 3101, Australia.;Univ Med Greifswald, Inst Diagnost Radiol & Neuroradiol, D-17489 Greifswald, Germany..
    Heslenfeld, Dirk J.
    German Ctr Neurodegenerat Dis DZNE, D-72076 Tubingen, Germany..
    Ho, Beng-Choon
    Vrije Univ Amsterdam, Dept Psychol, NL-1081 BT Amsterdam, Netherlands..
    Hoekstra, Pieter J.
    Univ Groningen, Dept Psychiat, Univ Med Ctr Groningen, NL-9700 RB Groningen, Netherlands..
    Hoffmann, Wolfgang
    Univ Med Greifswald, Inst Community Med, D-17489 Greifswald, Germany.;Univ Oxford, FMRIB Ctr, Oxford OX3 9DU, England..
    Hofman, Albert
    Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA..
    Holsboer, Florian
    Max Planck Inst Psychiat, D-80804 Munich, Germany.;Univ Iowa, Dept Psychiat, Iowa City, IA 52242 USA..
    Homuth, Georg
    Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA..
    Hosten, Norbert
    Osaka Univ, Mol Res Ctr Childrens Mental Dev, United Grad Sch Child Dev, Suita, Osaka 5650871, Japan..
    Hottenga, Jouke-Jan
    Vrije Univ Amsterdam, Biol Psychol, Amsterdam Neurosci, NL-1081 BT Amsterdam, Netherlands.;Vrije Univ Amsterdam, Med Ctr, NL-1081 BT Amsterdam, Netherlands..
    Huentelman, Matthew
    HMNC Brain Hlth, D-80539 Munich, Germany..
    Pol, Hilleke E. Hulshoff
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    Ikeda, Masashi
    Univ Med Greifswald, Interfac Inst Genet & Funct Genom, D-17489 Greifswald, Germany..
    Jack, Clifford R., Jr.
    Translat Genom Res Inst, Neurogen Div, 445N Fifth St, Phoenix, AZ 85004 USA..
    Jenkinson, Mark
    Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA..
    Johnson, Robert
    Fujita Hlth Univ, Sch Med, Dept Psychiat, Toyoake, Aichi 4701192, Japan..
    Joensson, Erik G.
    Univ Oslo, NORMENT KG Jebsen Ctr, Inst Clin Med, N-0315 Oslo, Norway.;Biospective Inc, 6100 Ave Royalmount, Montreal, PQ H4P 2R2, Canada..
    Jukema, J. Wouter
    Leiden Univ, Med Ctr, Dept Cardiol, NL-2300 RC Leiden, Netherlands..
    Kahn, Rene S.
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    Kanai, Ryota
    Mayo Clin, Dept Radiol, Rochester, MN 55905 USA.;Univ Maryland, Sch Med, NICHD Brain & Tissue Bank Dev Disorders, Baltimore, MD 21201 USA.;Univ Sussex, Sch Psychol, Brighton BN1 9QH, E Sussex, England..
    Kloszewska, Iwona
    UCL, Inst Cognit Neurosci, London WC1N 3AR, England..
    Knopman, David S.
    Araya Brain Imaging, Dept Neuroinformat, Tokyo 1020093, Japan..
    Kochunov, Peter
    Med Univ Lodz, PL-90419 Lodz, Poland..
    Kwok, John B.
    Mayo Clin, Dept Neurol, Rochester, MN 55905 USA.;Univ Maryland, Sch Med, Maryland Psychiat Res Ctr, Dept Psychiat, Catonsville, MD 21228 USA..
    Lawrie, Stephen M.
    Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh EH10 5HF, Midlothian, Scotland..
    Lemaitre, Herve
    Neurosci Res Australia, Randwick, NSW 2031, Australia..
    Liu, Xinmin
    NIMH, Human Genet Branch, Intramural Res Program, 35 Convent Dr,Rm 1A202, Bethesda, MD 20892 USA.;UNSW, Sch Med Sci, Sydney, NSW 2052, Australia..
    Longo, Dan L.
    Univ Paris 05, Univ Paris Saclay, INSERM UMR Neuroimaging & Psychiat 1000, Serv Hosp Freric Joliot,Univ Paris Sud,Maison Sol, F-91400 Orsay, France..
    Lopez, Oscar L.
    Columbia Univ, Med Ctr, New York, NY 10032 USA..
    Lovestone, Simon
    NIA, Genet Lab, NIH, Baltimore, MD 21224 USA.;Univ Pittsburgh, Dept Neurol, 3501 Forbes Ave,Suite 830, Pittsburgh, PA 15213 USA..
    Martinez, Oliver
    Bordeaux Univ Hosp, Dept Neurol, F-33076 Bordeaux, France..
    Martinot, Jean-Luc
    Neurosci Res Australia, Randwick, NSW 2031, Australia..
    Mattay, Venkata S.
    Lieber Inst Brain Dev, Baltimore, MD 21205 USA.;Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21287 USA.;Univ Oxford, Dept Psychiat, Oxford OX3 7JX, England..
    McDonald, Colm
    Univ New Mexico, Dept ECE, Albuquerque, NM 87131 USA..
    McIntosh, Andrew M.
    Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh EH10 5HF, Midlothian, Scotland..
    McMahon, Francis J.
    NIMH, Human Genet Branch, Intramural Res Program, 35 Convent Dr,Rm 1A202, Bethesda, MD 20892 USA..
    McMahon, Katie L.
    Johns Hopkins Univ, Sch Med, Dept Radiol, Baltimore, MD 21205 USA..
    Mecocci, Patrizia
    Univ Queensland, Ctr Adv Imaging, Brisbane, Qld 4072, Australia..
    Melle, Ingrid
    Univ Oslo, NORMENT KG Jebsen Ctr, Inst Clin Med, N-0315 Oslo, Norway.;Oslo Univ Hosp, NORMENT KG Jebsen Ctr, Div Mental Hlth & Addict, N-0424 Oslo, Norway..
    Meyer-Lindenberg, Andreas
    Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Dept Data Sci, D-68159 Mannheim, Germany..
    Mohnke, Sebastian
    Janssen Res & Dev LLC, Titusville, NJ 08560 USA..
    Montgomery, Grant W.
    QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia..
    Morris, Derek W.
    Oslo Univ Hosp, Dept Med Genet, N-0420 Oslo, Norway..
    Mosley, Thomas H.
    Univ Oslo, Dept Psychol, NORMENT KG Jebsen Ctr, N-0317 Oslo, Norway..
    Muhleisen, Thomas W.
    Univ Basel, Dept Biome, Div Med Genet, CH-4031 Basel, Switzerland.;Univ Bonn, Inst Human Genet, D-53127 Bonn, Germany..
    Mueller-Myhsok, Bertram
    Max Planck Inst Psychiat, D-80804 Munich, Germany.;Univ Perugia, Dept Med, Sect Gerontol & Geriatr, I-06132 Perugia, Italy.;Munich Cluster Syst Neurol SyNergy, D-81377 Munich, Germany..
    Nalls, Michael A.
    Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic 3101, Australia..
    Nauck, Matthias
    Univ Liverpool, Inst Translat Med, Liverpool L69 3BX, Merseyside, England.;Univ Med Greifswald, Inst Clin Chem & Lab Med, D-17489 Greifswald, Germany..
    Nichols, Thomas E.
    Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA.;German Ctr Cardiovascular Res DZHK eV, Partner Site Greifswald, D-17475 Greifswald, Germany..
    Niessen, Wiro J.
    Erasmus MC, Dept Radiol & Nucl Med, NL-3015 CE Rotterdam, Netherlands.;Univ Warwick, Dept Stat, Coventry CV4 7AL, W Midlands, England.;Univ Warwick, WMG, Coventry CV4 7AL, W Midlands, England.;Erasmus MC, Dept Med Informat, NL-3015 CE Rotterdam, Netherlands..
    Nothen, Markus M.
    Univ Basel, Dept Biome, Div Med Genet, CH-4031 Basel, Switzerland.;Delft Univ Technol, Fac Sci Appl, NL-2628 CD Delft, Netherlands..
    Nyberg, Lars
    Umea Univ, Dept Integrat Med Biol, S-90187 Umea, Sweden.;Umea Univ, Umea Ctr Funct Brain Imaging, S-90187 Umea, Sweden..
    Ohi, Kazutaka
    Univ Trondheim Hosp, Dept Radiol, St Olavs Hosp, N-7030 Trondheim, Norway..
    Olvera, Rene L.
    Indiana Univ Sch Med, Med & Mol Genet, Indianapolis, IN 46202 USA..
    Ophoff, Roel A.
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands.;Univ Calif Los Angeles, Ctr Neurobehav Genet, Los Angeles, CA 90095 USA..
    Pandolfo, Massimo
    Beaumont Hosp, Div Neurol, Dublin 9, Ireland..
    Paus, Tomas
    Univ Bonn, Dept Gen, Life & Brain Ctr, D-53127 Bonn, Germany.;Univ Toronto, Rotman Res Inst, Toronto, ON M6A 2E1, Canada.;Univ Toronto, Dept Psychol, Toronto, ON M5T 1R8, Canada.;Univ Toronto, Dept Psychiat, Toronto, ON M5T 1R8, Canada..
    Pausova, Zdenka
    Univ Toronto, Hosp Sick Children, Toronto, ON M5G 1X8, Canada.;Child Mind Inst, New York, NY 10022 USA..
    Penninx, Brenda W. J. H.
    Vrije Univ Amsterdam, Med Ctr, Dept Psychiat, Neurosci Campus Amsterdam, NL-1007 MB Amsterdam, Netherlands..
    Pike, G. Bruce
    Univ Toronto, Dept Physiol, Toronto, ON M5S 3E2, Canada.;Univ Toronto, Dept Nutr Sci, Toronto, ON M5S 3E2, Canada.;Univ Calgary, Dept Radiol, Calgary, AB T2N 4N1, Canada..
    Potkin, Steven G.
    Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA 92617 USA..
    Psaty, Bruce M.
    Univ Calgary, Dept Clin Neurosci, Calgary, AB T2N 4N1, Canada..
    Reppermund, Simone
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.;Univ Washington, Dept Med, Seattle, WA USA.;Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA.;USA Grp Hlth Res Inst, Grp Hlth, 1730 Minor Ave Suite 1360, Seattle, WA 98101 USA..
    Rietschel, Marcella
    Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Dept Data Sci, D-68159 Mannheim, Germany..
    Roffman, Joshua L.
    Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA..
    Romanczuk-Seiferth, Nina
    Janssen Res & Dev LLC, Titusville, NJ 08560 USA..
    Rotter, Jerome I.
    Univ New South Wales, Dept Dev Disabil Neuropsychiat, Sch Psychiat, Sydney, NSW 2052, Australia..
    Ryten, Mina
    UCL Inst Neurol, Reta Lila Weston Inst, London WC1N 3BG, England.;UCL Inst Neurol, Dept Mol Neurosci, London WC1N 3BG, England.;Kings Coll London, Dept Med & Mol Genet, London SE1 9RT, England..
    Sacco, Ralph L.
    Univ Miami, Miller Sch Med, John P Hussman Inst Human Gen, Miami, FL 33136 USA.;Univ Miami, Miller Sch Med, Dept Neurol, Miami, FL 33136 USA.;Univ Miami, Miller Sch Med, Dept Epidemiol & Publ Hlth Sci, Miami, FL 33136 USA.;Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Los Angeles Biomed Res Inst & Pediat, Torrance, CA 90502 USA..
    Sachdev, Perminder S.
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia.;Univ Miami, Miller Sch Med, Evelyn F McKnight Brain Inst, Miami, FL 33136 USA..
    Saykin, Andrew J.
    Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA.;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA.;Univ Texas Hlth Sci Ctr Houston, Inst Mol Med & Human Genet Ctr, Houston, TX 77030 USA..
    Schmidt, Reinhold
    Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Auenbruggerpl 22, A-8036 Graz, Austria..
    Schmidt, Helena
    Prince Wales Hosp, Neuropsychiat Inst, Randwick, NSW 2031, Australia..
    Schofield, Peter R.
    Mayo Clin, Dept Neurol, Rochester, MN 55905 USA.;Univ Maryland, Sch Med, Maryland Psychiat Res Ctr, Dept Psychiat, Catonsville, MD 21228 USA..
    Sigursson, Sigurdur
    Iceland Heart Assoc, IS-201 Kopavogur, Iceland..
    Simmons, Andrew
    Med Univ Graz, Inst Mol Biol & Biochem, Harrachgasse 21-3, A-8010 Graz, Austria.;Kings Coll London, Inst Psychiat, Dept Neuroimaging, London SE5 8AF, England.;Kings Coll London, Biomed Res Ctr Mental Hlth, London SE5 8AF, England..
    Singleton, Andrew
    Sisodiya, Sanjay M.
    UCL Inst Neurol, London, England.;Epilepsy Soc, St Peter, Bucks, England..
    Smith, Colin
    Kings Coll London, Biomed Res Unit Dementia, London SE5 8AF, England..
    Smoller, Jordan W.
    Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Stanley Ctr Psychiat Res, Boston, MA 02141 USA..
    Soininen, Hilkka
    Univ Edinburgh, Acad Dept Neuropathol, Ctr Clin Brain Sci, MRC Edinburgh Brain Bank, Edinburgh EH16 4SB, Midlothian, Scotland.;Univ Eastern Finland, Inst Clin Med, Neurol, FI-70211 Kuopio, Finland..
    Steen, Vidar M.
    Univ Bergen, Dept Clin Sci, NORMENT KG Jebsen Ctr Psychosis Res, N-5021 Bergen, Norway.;Haukeland Hosp, Dr Einar Martens Res Grp Biol Psychiat, Ctr Med Genet & Mol Med, N-5021 Bergen, Norway..
    Stott, David J.
    Kuopio Univ Hosp, Neuroctr Neurol, FI-70211 Kuopio, Finland..
    Sussmann, Jessika E.
    Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh EH10 5HF, Midlothian, Scotland..
    Thalamuthu, Anbupalam
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia..
    Toga, Arthur W.
    Univ Glasgow, Fac Med, Inst Cardiovasc & Med Sci, Glasgow G4 0SF, Lanark, Scotland..
    Traynor, Bryan J.
    Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic 3101, Australia..
    Troncoso, Juan
    Univ Southern Calif, Lab Neuro Imaging, Inst Neuroimaging & Informat, Keck Sch Med, Los Angeles, CA 90033 USA..
    Tsolaki, Magda
    Johns Hopkins Univ, Dept Pathol, Baltimore, MD 21205 USA..
    Tzourio, Christophe
    Univ Bordeaux, INSERM Unit U1219, F-33076 Bordeaux, France.;Aristotle Univ Thessaloniki, Dept Neurol 3, G Papanicolaou Hosp, Thessaloniki 57010, Greece..
    Uitterlinden, Andre G.
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands.;Univ Bordeaux, INSERM, Bordeaux Populat Hlth Res Ctr, UMR1219, F-33000 Bordeaux, France..
    Hernandez, Maria C. Valdes
    Van der Brug, Marcel
    Erasmus MC, Dept Internal Med, NL-3015 CE Rotterdam, Netherlands..
    van der Lugt, Aad
    Erasmus MC, Dept Radiol & Nucl Med, NL-3015 CE Rotterdam, Netherlands..
    van der Wee, Nic J. A.
    Genentech Inc, San Francisco, CA 94080 USA..
    Van Haren, Neeltje E. M.
    UMC Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CX Utrecht, Netherlands..
    van't Ent, Dennis
    Vrije Univ Amsterdam, Biol Psychol, Amsterdam Neurosci, NL-1081 BT Amsterdam, Netherlands.;Vrije Univ Amsterdam, Med Ctr, NL-1081 BT Amsterdam, Netherlands..
    Van Tol, Marie-Jose
    Leiden Univ, Med Ctr, Dept Psychiat, NL-2333 ZA Leiden, Netherlands.;Leiden Univ, Med Ctr, Leiden Inst Brain & Cognit, NL-2333 ZA Leiden, Netherlands..
    Vardarajan, Badri N.
    Columbia Univ, Med Ctr, Taub Inst Res Alzheimers Dis & Aging Brain, 639 West 1168th St, New York, NY 10032 USA.;Columbia Univ, Med Ctr, GH Sergievsky Ctr, 639 West 1168th St, New York, NY 10032 USA.;Columbia Univ, Med Ctr, Dept Neurol, 639 West 1168th St, New York, NY 10032 USA..
    Vellas, Bruno
    Univ Groningen, Univ Med Ctr Groningen, Dept Neurosci, NL-9713 AW Groningen, Netherlands..
    Veltman, Dick J.
    Vrije Univ Amsterdam, Med Ctr, Dept Psychiat, Neurosci Campus Amsterdam, NL-1007 MB Amsterdam, Netherlands..
    Voelzke, Henry
    Univ Med Greifswald, Inst Community Med, D-17489 Greifswald, Germany..
    Walter, Henrik
    Janssen Res & Dev LLC, Titusville, NJ 08560 USA..
    Wardlaw, Joanna M.
    Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh EH4 2XU, Midlothian, Scotland.;Univ Edinburgh, Dept Neuroimaging Sci, Scottish Imaging Network, Platform Sci Excellence SINAPSE Collaborat, Edinburgh EH16 4SB, Midlothian, Scotland.;Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh EH16 4SB, Midlothian, Scotland..
    Wassink, Thomas H.
    Univ Toulouse, Dept Internal Med & Geriatr Med, INSERM U1027, F-31024 Toulouse, France..
    Weale, Michael E.
    Kings Coll London, Dept Med & Mol Genet, London SE1 9RT, England..
    Weinberger, Daniel R.
    Lieber Inst Brain Dev, Baltimore, MD 21205 USA.;Univ Iowa, Carver Coll Med, Dept Psychiat, Iowa City, IA 52242 USA..
    Weiner, Michael W.
    Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21287 USA.;Johns Hopkins Univ, Sch Med, Dept Psychiat, Baltimore, MD 21205 USA.;Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA.;Johns Hopkins Univ, Sch Med, Inst Med Genet, Baltimore, MD 21205 USA..
    Wen, Wei
    Univ New South Wales, Ctr Healthy Brain Ageing, Sch Psychiat, Sydney, NSW 2052, Australia.;Univ Miami, Miller Sch Med, Evelyn F McKnight Brain Inst, Miami, FL 33136 USA..
    Westman, Eric
    Univ Calif San Francisco, Ctr Imaging Neurodegenerat Dis, San Francisco VA Med Ctr, San Francisco, CA 94121 USA..
    White, Tonya
    Erasmus MC, Dept Radiol & Nucl Med, NL-3015 CE Rotterdam, Netherlands.;Karolinska Inst, Dept Neurobiol, Care Sci & Soc, SE-14157 Huddinge, Sweden..
    Wong, Tien Y.
    Duke NUS Grad Med Sch, Acad Med Res Inst, Singapore 169857, Singapore.;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore 168751, Singapore.;Natl Univ Ireland Galway, Ctr Neuroimaging & Cognit Genom NICOG, Clin Neuroimaging Lab, NCBES Galway Neurosci Ctr,Coll Med Nursing & Hlth, Galway H91 TK33, Ireland..
    Wright, Clinton B.
    Univ Miami, Miller Sch Med, Dept Neurol, Miami, FL 33136 USA.;Univ Miami, Miller Sch Med, Dept Epidemiol & Publ Hlth Sci, Miami, FL 33136 USA.;Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Los Angeles Biomed Res Inst & Pediat, Torrance, CA 90502 USA..
    Zielke, Ronald H.
    Fujita Hlth Univ, Sch Med, Dept Psychiat, Toyoake, Aichi 4701192, Japan..
    Zonderman, Alan B.
    Erasmus MC Sophia Childrens Hosp, Dept Child & Adolescent Psychiat Psychol, NL-3015 CE Rotterdam, Netherlands..
    Martin, Nicholas G.
    QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia..
    Van Duijn, Cornelia M.
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands..
    Wright, Margaret J.
    Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia.;Johns Hopkins Univ, Sch Med, Dept Radiol, Baltimore, MD 21205 USA..
    Longstreth, W. T.
    NIA, Lab Epidemiol & Populat Sci, NIH, Bethesda, MD 20892 USA..
    Schumann, Gunter
    Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London SE5 8AF, England..
    Grabe, Hans J.
    Univ Med Greifswald, Dept Psychiat, D-17489 Greifswald, Germany..
    Franke, Barbara
    Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Med Ctr, Dept Psychiat, NL-6525 GA Nijmegen, Netherlands.;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, NL-6525 GA Nijmegen, Netherlands..
    Launer, Lenore J.
    Univ Washington, Dept Neurol, 325 Ninth Ave, Washington, DC 98104 USA.;Univ Washington, Dept Epidemiol, 325 Ninth Ave, Seattle, WA 98104 USA..
    Medland, Sarah E.
    QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia..
    Seshadri, Sudha
    Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA.;Framingham Heart Dis Epidemiol Study, 17 Mt Wayte Ave, Framingham, MA 01703 USA..
    Thompson, Paul M.
    Univ Southern Calif, Imaging Genet Ctr, USC Mark & Mary Stevens Neuroimaging & Informat I, Keck Sch Med, Marina Del Rey, CA 90292 USA..
    Ikram, M. Arfan
    Erasmus Univ, Med Ctr, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands.;Erasmus MC, Dept Radiol & Nucl Med, NL-3015 CE Rotterdam, Netherlands.;NIA, Intramural Res Program, NIH, Bethesda, MD 20892 USA. Erasmus MC, Dept Neurol, NL-3015 CE Rotterdam, Netherlands..
    Novel genetic loci associated with hippocampal volume2017Ingår i: Nature Communications, ISSN 2041-1723, E-ISSN 2041-1723, Vol. 8, 13624Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (r(g) = -0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.

  • 8.
    Häggblad Sahlberg, Sara
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi.
    Mortensen, Anja C.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Medicinsk strålningsvetenskap.
    Haglöf, Jakob
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för läkemedelskemi, Avdelningen för analytisk farmaceutisk kemi.
    Engskog, Mikael K. R.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för läkemedelskemi, Avdelningen för analytisk farmaceutisk kemi.
    Arvidsson, Torbjörn
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för läkemedelskemi, Avdelningen för analytisk farmaceutisk kemi.
    Pettersson, Curt
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Farmaceutiska fakulteten, Institutionen för läkemedelskemi, Avdelningen för analytisk farmaceutisk kemi.
    Glimelius, Bengt
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Experimentell och klinisk onkologi.
    Stenerlöw, Bo
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Medicinsk strålningsvetenskap.
    Nestor, Marika
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Medicinsk strålningsvetenskap. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells2017Ingår i: International Journal of Oncology, ISSN 1019-6439, Vol. 50, nr 1, 5-14 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    AKT is a central protein in many cellular pathways such as cell survival, proliferation, glucose uptake, metabolism, angiogenesis, as well as radiation and drug response. The three isoforms of AKT (AKT1, AKT2 and AKT3) are proposed to have different physiological functions, properties and expression patterns in a cell type-dependent manner. As of yet, not much is known about the influence of the different AKT isoforms in the genome and their effects in the metabolism of colorectal cancer cells. In the present study, DLD-1 isogenic AKT1, AKT2 and AKT'/2 knockout colon cancer cell lines were used as a model system in conjunction with the parental cell line in order to further elucidate the differences between the AKT isoforms and how they are involved in various cellular pathways. This was done using genome wide expression analyses, metabolic profiling and cell migration assays. In conclusion, downregulation of genes in the cell adhesion, extracellular matrix and Notch-pathways and upregulation of apoptosis and metastasis inhibitory genes in the p53-pathway, confirm that the knockout of both AKT1 and AKT2 will attenuate metastasis and tumor cell growth. This was verified with a reduction in migration rate in the AKT1 KO and AKT2 KO and most explicitly in the AKT1/2 KO. Furthermore, the knockout of AKT1, AKT2 or both, resulted in a reduction in lactate and alanine, suggesting that the metabolism of carbohydrates and glutathione was impaired. This was further verified in gene expression analyses, showing downregulation of genes involved in glucose metabolism. Additionally, both AKT1 KO and AKT2 KO demonstrated an impaired fatty acid metabolism. However, genes were upregulated in the Wnt and cell proliferation pathways, which could oppose this effect. AKT inhibition should therefore be combined with other effectors to attain the best effect.

  • 9.
    Habiba, G.
    et al.
    Univ Addis Ababa, Ethiopian Inst Water Resources, Addis Ababa, Ethiopia.
    Abebe, G.
    Univ Addis Ababa, Dept Zool Sci, Addis Ababa, Ethiopia.
    Bravo, Andrea G.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Limnologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Ermias, D.
    Hawassa Univ, Addis Ababa, Ethiopia.
    Staffan, Ǻ.
    Swedish Univ Agr Sci, Dept Aquat Sci & Assessment, Uppsala, Sweden.
    Bishop, Kevin
    Swedish Univ Agr Sci, Dept Aquat Sci & Assessment, Uppsala, Sweden.
    Mercury Human Exposure in Populations Living Around Lake Tana (Ethiopia)2017Ingår i: Biological Trace Element Research, ISSN 0163-4984, E-ISSN 1559-0720, Vol. 175, nr 2, 237-243 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A survey carried out in Lake Tana in 2015 found that Hg levels in some fish species exceeded internationally accepted safe levels for fish consumption. The current study assesses human exposure to Hg through fish consumption around the Lake Tana. Of particular interest was that a dietary intake of fishes is currently a health risk for Bihar Dar residents and anglers. Hair samples were collected from three different groups: anglers, college students and teachers, and daily laborers. A questionary includes gender, age, weight, activity. Frequency of fish consumption and origin of the eaten fish were completed by each participant. Mercury concentrations in hair were significantly higher (P value <0.05) for anglers (mean ± standard deviation 0.120 ± 0.199 μg/g) than college students (mean ± standard deviation 0.018 ± 0.039 μg/g) or daily workers (mean ± standard deviation 16 ± 9.5 ng/g). Anglers consumed fish more often than daily workers and college group. Moreover, there was also a strong correlation (P value <0.05) between the logarithms of total mercury and age associated with mercury concentration in scalp hair. Mercury concentrations in the hair of men were on average twice the value of the women. Also, users of skin lightening soap on a daily basis had 2.5 times greater mercury in scalp hair than non-users. Despite the different sources of mercury exposure mentioned above, the mercury concentrations of the scalp hair of participants of this study were below levels deemed to pose a threat to health.

  • 10. Chu, Audrey Y
    et al.
    Deng, Xuan
    Fisher, Virginia A
    Drong, Alexander
    Zhang, Yang
    Feitosa, Mary F
    Liu, Ching-Ti
    Weeks, Olivia
    Choh, Audrey C
    Duan, Qing
    Dyer, Thomas D
    Eicher, John D
    Guo, Xiuqing
    Heard-Costa, Nancy L
    Kacprowski, Tim
    Kent, Jack W
    Lange, Leslie A
    Liu, Xinggang
    Lohman, Kurt
    Lu, Lingyi
    Mahajan, Anubha
    O'Connell, Jeffrey R
    Parihar, Ankita
    Peralta, Juan M
    Smith, Albert V
    Zhang, Yi
    Homuth, Georg
    Kissebah, Ahmed H
    Kullberg, Joel
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Radiologi.
    Laqua, René
    Launer, Lenore J
    Nauck, Matthias
    Olivier, Michael
    Peyser, Patricia A
    Terry, James G
    Wojczynski, Mary K
    Yao, Jie
    Bielak, Lawrence F
    Blangero, John
    Borecki, Ingrid B
    Bowden, Donald W
    Carr, John Jeffrey
    Czerwinski, Stefan A
    Ding, Jingzhong
    Friedrich, Nele
    Gudnason, Vilmunder
    Harris, Tamara B
    Ingelsson, Erik
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Molekylär epidemiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Johnson, Andrew D
    Kardia, Sharon L R
    Langefeld, Carl D
    Lind, Lars
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Radiologi.
    Liu, Yongmei
    Mitchell, Braxton D
    Morris, Andrew P
    Mosley, Thomas H
    Rotter, Jerome I
    Shuldiner, Alan R
    Towne, Bradford
    Völzke, Henry
    Wallaschofski, Henri
    Wilson, James G
    Allison, Matthew
    Lindgren, Cecilia M
    Goessling, Wolfram
    Cupples, L Adrienne
    Steinhauser, Matthew L
    Fox, Caroline S
    Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation2017Ingår i: Nature Genetics, ISSN 1061-4036, E-ISSN 1546-1718, Vol. 49, nr 1, 125-130 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Variation in body fat distribution contributes to the metabolic sequelae of obesity. The genetic determinants of body fat distribution are poorly understood. The goal of this study was to gain new insights into the underlying genetics of body fat distribution by conducting sample-size-weighted fixed-effects genome-wide association meta-analyses in up to 9,594 women and 8,738 men of European, African, Hispanic and Chinese ancestry, with and without sex stratification, for six traits associated with ectopic fat (hereinafter referred to as ectopic-fat traits). In total, we identified seven new loci associated with ectopic-fat traits (ATXN1, UBE2E2, EBF1, RREB1, GSDMB, GRAMD3 and ENSA; P < 5 × 10(-8); false discovery rate < 1%). Functional analysis of these genes showed that loss of function of either Atxn1 or Ube2e2 in primary mouse adipose progenitor cells impaired adipocyte differentiation, suggesting physiological roles for ATXN1 and UBE2E2 in adipogenesis. Future studies are necessary to further explore the mechanisms by which these genes affect adipocyte biology and how their perturbations contribute to systemic metabolic disease.

  • 11.
    Laxman, Navya
    et al.
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Endokrinologi och mineralmetabolism.
    Mallmin, Hans
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Ortopedi.
    Nilsson, Olle
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Ortopedi.
    Kindmark, Andreas
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Endokrinologi och mineralmetabolism. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    miR-203 and miR-320 regulate Bone Morphogenetic Protein-2-induced osteoblast differentiation by targeting Distal-less Homeobox 5 (Dlx5)2017Ingår i: Genes, ISSN 2073-4425, Vol. 8, nr 1, E4Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    MicroRNAs (miRNAs) are a family of small, non-coding RNAs (17–24 nucleotides), which regulate gene expression either by the degradation of the target mRNAs or inhibiting the translation of genes. Recent studies have indicated that miRNA plays an important role in regulating osteoblast differentiation. In this study, we identified miR-203 and miR-320b as important miRNAs modulating osteoblast differentiation. We identified Dlx5 as potential common target by prediction algorithms and confirmed this by knock-down and over expression of the miRNAs and assessing Dlx5 at mRNA and protein levels and specificity was verified by luciferase reporter assays. We examined the effect of miR-203 and miR-320b on osteoblast differentiation by transfecting with pre- and anti-miRs. Over-expression of miR-203 and miR-320b inhibited osteoblast differentiation, whereas inhibition of miR-203 and miR-320b stimulated alkaline phosphatase activity and matrix mineralization. We show that miR-203 and miR-320b negatively regulate BMP-2-induced osteoblast differentiation by suppressing Dlx5, which in turn suppresses the downstream osteogenic master transcription factor Runx2 and Osx and together they suppress osteoblast differentiation. Taken together, we propose a role for miR-203 and miR-320b in modulating bone metabolism.

  • 12.
    Gremel, Gabriela
    et al.
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi.
    Djureinovic, Dijana
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Klinisk och experimentell patologi.
    Niinivirta, Marjut
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Experimentell och klinisk onkologi.
    Laird, Alexander
    Univ Edinburgh, MRC Human Genet Unit, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Inst Genet & Mol Med, Edinburgh Urol Canc Grp, Edinburgh, Midlothian, Scotland..
    Ljungqvist, Oscar
    Atlas Antibodies AB, Stockholm, Sweden..
    Johannesson, Henrik
    Atlas Antibodies AB, Stockholm, Sweden..
    Bergman, Julia
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Klinisk och experimentell patologi.
    Edqvist, Per-Henrik D
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Experimentell och klinisk onkologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Navani, Sanjay
    Lab Surgpath, Bombay, Maharashtra, India..
    Khan, Naila
    Lab Surgpath, Bombay, Maharashtra, India..
    Patil, Tushar
    Lab Surgpath, Bombay, Maharashtra, India..
    Sivertsson, Asa
    Royal Inst Technol, Sci Life Lab, Stockholm, Sweden..
    Uhlen, Mathias
    Royal Inst Technol, Sci Life Lab, Stockholm, Sweden..
    Harrison, David J.
    Univ St Andrews, Sch Med, St Andrews, Fife, Scotland..
    Ullenhag, Gustav
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Experimentell och klinisk onkologi.
    Stewart, Grant D.
    Univ Edinburgh, Inst Genet & Mol Med, Edinburgh Urol Canc Grp, Edinburgh, Midlothian, Scotland.;Univ Cambridge, Addenbrookes Hosp, Acad Urol Grp, Box 43,Cambridge Biomed Campus,Hills Rd, Cambridge CB2 0QQ, England..
    Pontén, Fredrik
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Klinisk och experimentell patologi.
    A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma2017Ingår i: BMC Cancer, ISSN 1471-2407, E-ISSN 1471-2407, Vol. 17, 9Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: There is an unmet clinical need for better prognostic and diagnostic tools for renal cell carcinoma (RCC). Methods: Human Protein Atlas data resources, including the transcriptomes and proteomes of normal and malignant human tissues, were searched for RCC-specific proteins and cubilin (CUBN) identified as a candidate. Patient tissue representing various cancer types was constructed into a tissue microarray (n = 940) and immunohistochemistry used to investigate the specificity of CUBN expression in RCC as compared to other cancers. Two independent RCC cohorts (n = 181; n = 114) were analyzed to further establish the sensitivity of CUBN as RCC-specific marker and to explore if the fraction of RCCs lacking CUBN expression could predict differences in patient survival. Results: CUBN was identified as highly RCC-specific protein with 58% of all primary RCCs staining positive for CUBN using immunohistochemistry. In venous tumor thrombi and metastatic lesions, the frequency of CUBN expression was increasingly lost. Clear cell RCC (ccRCC) patients with CUBN positive tumors had a significantly better prognosis compared to patients with CUBN negative tumors, independent of T-stage, Fuhrman grade and nodal status (HR 0.382, CI 0.203-0.719, P = 0.003). Conclusions: CUBN expression is highly specific to RCC and loss of the protein is significantly and independently associated with poor prognosis. CUBN expression in ccRCC provides a promising positive prognostic indicator for patients with ccRCC. The high specificity of CUBN expression in RCC also suggests a role as a new diagnostic marker in clinical cancer differential diagnostics to confirm or rule out RCC.

  • 13.
    Amrein, Beat Anton
    et al.
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för cell- och molekylärbiologi, Struktur- och molekylärbiologi.
    Steffen-Munsberg, Fabian
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för cell- och molekylärbiologi, Struktur- och molekylärbiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Szeler, Ireneusz
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för cell- och molekylärbiologi, Struktur- och molekylärbiologi.
    Purg, Miha
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för cell- och molekylärbiologi, Struktur- och molekylärbiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Kulkarni, Yashraj
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för cell- och molekylärbiologi, Struktur- och molekylärbiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Kamerlin, Shina Caroline Lynn
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för cell- och molekylärbiologi, Struktur- och molekylärbiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    CADEE: Computer-Aided Directed Evolution of Enzymes2017Ingår i: IUCrJ, ISSN 0972-6918, E-ISSN 2052-2525, Vol. 4, nr 1, 50-64 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The tremendous interest in enzymes as biocatalysts has led to extensive work in enzyme engineering, as well as associated methodology development. Here, a new framework for computer-aided directed evolution of enzymes (CADEE) is presented which allows a drastic reduction in the time necessary to prepare and analyze in silico semi-automated directed evolution of enzymes. A pedagogical example of the application of CADEE to a real biological system is also presented in order to illustrate the CADEE workflow.

  • 14.
    Schuette, Moritz
    et al.
    Alacris Theranost GmbH, Fabeckstr 60-62, D-14195 Berlin, Germany..
    Risch, Thomas
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, Otto Warburg Lab Gene Regulat & Syst Biol Canc, Ihnestr 73, D-14195 Berlin, Germany..
    Abdavi-Azar, Nilofar
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, Otto Warburg Lab Gene Regulat & Syst Biol Canc, Ihnestr 73, D-14195 Berlin, Germany..
    Boehnke, Karsten
    Eli Lilly & Co, Lilly Res Labs, Quantitat Biol, Avda Ind 30, Madrid 28108, Spain..
    Schumacher, Dirk
    Charite Univ Med Berlin, Inst Pathol, Lab Mol Tumour Pathol, Charitepl 1, D-10117 Berlin, Germany.;German Canc Res Ctr, German Canc Consortium DKTK, Neuenheimer Feld 280, D-69192 Heidelberg, Germany..
    Keil, Marlen
    Expt Pharmacol & Oncol Berlin Buch GmbH EPO, Robert Roessle Str 10, D-13125 Berlin, Germany..
    Yildirimman, Reha
    Alacris Theranost GmbH, Fabeckstr 60-62, D-14195 Berlin, Germany..
    Jandrasits, Christine
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, Otto Warburg Lab Gene Regulat & Syst Biol Canc, Ihnestr 73, D-14195 Berlin, Germany..
    Borodina, Tatiana
    Alacris Theranost GmbH, Fabeckstr 60-62, D-14195 Berlin, Germany..
    Amstislavskiy, Vyacheslav
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, Otto Warburg Lab Gene Regulat & Syst Biol Canc, Ihnestr 73, D-14195 Berlin, Germany..
    Worth, Catherine L.
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, Otto Warburg Lab Gene Regulat & Syst Biol Canc, Ihnestr 73, D-14195 Berlin, Germany..
    Schweiger, Caroline
    Med Univ Graz, Inst Pathol, Auenbruggerpl 25, A-8036 Graz, Austria..
    Liebs, Sandra
    Charite, Charitepl 1, D-10117 Berlin, Germany..
    Lange, Martin
    Bayer Pharma AG, Mullerstr 178, D-13353 Berlin, Germany..
    Warnatz, Hans-Joerg
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, Otto Warburg Lab Gene Regulat & Syst Biol Canc, Ihnestr 73, D-14195 Berlin, Germany..
    Butcher, Lee M.
    UCL, Inst Canc, London WC1E 6BT, England.;Imperial Coll London, Dept Surg & Canc, London W12 0NN, England..
    Barrett, James E.
    UCL, Inst Canc, London WC1E 6BT, England..
    Sultan, Marc
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, Otto Warburg Lab Gene Regulat & Syst Biol Canc, Ihnestr 73, D-14195 Berlin, Germany..
    Wierling, Christoph
    Alacris Theranost GmbH, Fabeckstr 60-62, D-14195 Berlin, Germany..
    Golob-Schwarzl, Nicole
    Ctr Biomarker Res Med, Stiftingtalstr 5, A-8010 Graz, Austria..
    Lax, Sigurd
    Hosp Graz Sud West, Dept Pathol, Gostinger Str 22, A-8020 Graz, Austria..
    Uranitsch, Stefan
    Hosp Bros Char Graz, Dept Surg, Marschallgasse 12, A-8020 Graz, Austria..
    Becker, Michael
    Expt Pharmacol & Oncol Berlin Buch GmbH EPO, Robert Roessle Str 10, D-13125 Berlin, Germany..
    Welte, Yvonne
    Charite Univ Med Berlin, Inst Pathol, Lab Mol Tumour Pathol, Charitepl 1, D-10117 Berlin, Germany.;Berlin Buch GmbH, CPO Cellular Phenom & Oncol, Robert Rossle Str 10, D-13125 Berlin, Germany..
    Regan, Joseph Lewis
    Bayer Pharma AG, Mullerstr 178, D-13353 Berlin, Germany..
    Silvestrov, Maxine
    Charite Univ Med Berlin, Inst Pathol, Lab Mol Tumour Pathol, Charitepl 1, D-10117 Berlin, Germany.;Berlin Buch GmbH, CPO Cellular Phenom & Oncol, Robert Rossle Str 10, D-13125 Berlin, Germany..
    Kehler, Inge
    Charite, Charitepl 1, D-10117 Berlin, Germany..
    Fusi, Alberto
    Charite, Charitepl 1, D-10117 Berlin, Germany..
    Kessler, Thomas
    Alacris Theranost GmbH, Fabeckstr 60-62, D-14195 Berlin, Germany..
    Herwig, Ralf
    Max Planck Inst Mol Genet, Dept Computat Mol Biol, Ihnestr 73, D-14195 Berlin, Germany..
    Landegren, Ulf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Molekylära verktyg. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Wienke, Dirk
    Merck KGaA, Frankfurter Str 250, D-64293 Darmstadt, Germany..
    Nilsson, Mats
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Molekylära verktyg. Uppsala universitet, Science for Life Laboratory, SciLifeLab. Stockholm Univ, Dept Biochem & Biophys, Sci Life Lab, Tomtebodavagem 23A, S-17165 Stockholm, Sweden..
    Velasco, Juan A.