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  • 1.
    Algers, Bo
    Swedish University of Agricultural Sciences.
    45 Contemporary Issues in Farm Animal Housing and Management: Swine2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 329-337Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 2.
    Appleby, Michael C.
    World Society for the Protection of Animals, London.
    49 Can Farm Animal Welfare Standards be Compatible with Free Trade?2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 352-357Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 3.
    Arney, David
    Estonian University of Life Sciences, Tartu.
    42 What is Animal Welfare and How is it Assessed?2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 311-315Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 4.
    Arney, David
    et al.
    Estonian University of Life Sciences, Tartu.
    Aland, Andres
    Estonian University of Life Sciences, Tartu.
    44 Contemporary Issues in Farm Animal Housing and Management: Cattle Housing and Welfare2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 324-328Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 5.
    Arney, David
    et al.
    Estonian University of Life Sciences, Tartu.
    Aland, Andres
    47 Humane Transport and Slaughter of Farm Animals2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 344-348Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 6.
    Berg, Charlotte
    Swedish University of Agricultural Sciences .
    48 Monitoring Animal Welfare at Slaughterhouses2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 349-351Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 7. Carneiro, Miguel
    et al.
    Piorno, Vicente
    Rubin, Carl-Johan
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi.
    Alves, Joel M.
    Ferrand, Nuno
    Alves, Paulo C.
    Andersson, Leif
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi.
    Candidate genes underlying heritable differences in reproductive seasonality between wild and domestic rabbits2015Inngår i: Animal Genetics, ISSN 0268-9146, E-ISSN 1365-2052, Vol. 46, nr 4, s. 418-425Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Reproductive seasonality is a trait that often differs between domestic animals and their wild ancestors, with domestic animals showing prolonged or even continuous breeding seasons. However, the genetic basis underlying this trait is still poorly understood for most species, and because environmental factors and resource availability are known to play an important role in determining breeding seasons, it is also not clear in most cases to what extent this phenotypic shift is determined by the more lenient captive conditions or by genetic factors. Here, using animals resulting from an initial cross between wild and domestic rabbits followed by two consecutive backcrosses (BC1 and BC2) to wild rabbits, we evaluated the yearly distribution of births for the different generations. Similar to domestic rabbits, F1 animals could be bred all year round but BC1 and BC2 animals showed a progressive and significant reduction in the span of the breeding season, providing experimental evidence that reduced seasonal breeding in domestic rabbits has a clear genetic component and is not a simple by-product of rearing conditions. We then took advantage of a recently published genome-wide scan of selection in the domesticated lineage and searched for candidate genes potentially associated with this phenotypic shift. Candidate genes located within regions targeted by selection include well-known examples of genes controlling clock functions (CRY1 and NR3C1) and reproduction (PRLR).

  • 8.
    Chee-Sanford, Joanne C.
    et al.
    U.S. Department of Agriculture , Agricultural Research Service, Urbana, IL, USA.
    Krapac, Ivan J.
    Illinois State Geological Survey, Champaign, IL, USA.
    Yannarell, Anthony C.
    University of Illinois at Urbana-Champaign.
    Mackie, Roderick I.
    University of Illinois at Urbana-Champaign.
    29. Environmental Impacts of Antibiotic Use in the Animal Production Industry2012Inngår i: Ecology and Animal Health / [ed] Leif Norrgren and Jeffrey Levengood, Uppsala: Baltic University Press , 2012, 2, s. 228-239Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 9. Groenen, M. A.
    et al.
    Archibald, A. L.
    Uenishi, H.
    Tuggle, C. K.
    Takeuchi, Y.
    Rothschild, M. F.
    Rogel-Gaillard, C.
    Park, C.
    Milan, D.
    Megens, H. J.
    Li, S.
    Larkin, D. M.
    Kim, H.
    Frantz, L. A.
    Caccamo, M.
    Ahn, H.
    Aken, B. L.
    Anselmo, A.
    Anthon, C.
    Auvil, L.
    Badaoui, B.
    Beattie, C. W.
    Bendixen, C.
    Berman, D.
    Blecha, F.
    Blomberg, Jonas
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Klinisk mikrobiologi och infektionsmedicin, Klinisk virologi.
    Bolund, L.
    Bosse, M.
    Botti, S.
    Bujie, Z.
    Byström, M.
    Capitanu, B.
    Carvalho-Silva, D.
    Chardon, P.
    Chen, C.
    Cheng, R.
    Choi, S. H.
    Chow, W.
    Clark, R. C.
    Clee, C.
    Crooijmans, R. P.
    Dawson, H. D.
    Dehais, P.
    De Sapio, F.
    Dibbits, B.
    Drou, N.
    Du, Z. Q.
    Eversole, K.
    Fadista, J.
    Fairley, S.
    Faraut, T.
    Faulkner, G. J.
    Fowler, K. E.
    Fredholm, M.
    Fritz, E.
    Gilbert, J. G.
    Giuffra, E.
    Gorodkin, J.
    Griffin, D. K.
    Harrow, J. L.
    Hayward, Alexander
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Howe, K.
    Hu, Z. L.
    Humphray, S. J.
    Hunt, T.
    Hornshoj, H.
    Jeon, J. T.
    Jern, Patric
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Jones, M.
    Jurka, J.
    Kanamori, H.
    Kapetanovic, R.
    Kim, J.
    Kim, J. H.
    Kim, K. W.
    Kim, T. H.
    Larson, G.
    Lee, K.
    Lee, K. T.
    Leggett, R.
    Lewin, H. A.
    Li, Y.
    Liu, W.
    Loveland, J. E.
    Lu, Y.
    Lunney, J. K.
    Ma, J.
    Madsen, O.
    Mann, K.
    Matthews, L.
    McLaren, S.
    Morozumi, T.
    Murtaugh, M. P.
    Narayan, J.
    Nguyen, D. T.
    Ni, P.
    Oh, S. J.
    Onteru, S.
    Panitz, F.
    Park, E. W.
    Park, H. S.
    Pascal, G.
    Paudel, Y.
    Perez-Enciso, M.
    Ramirez-Gonzalez, R.
    Reecy, J. M.
    Rodriguez-Zas, S.
    Rohrer, G. A.
    Rund, L.
    Sang, Y.
    Schachtschneider, K.
    Schraiber, J. G.
    Schwartz, J.
    Scobie, L.
    Scott, C.
    Searle, S.
    Servin, B.
    Southey, B. R.
    Sperber, Göran
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Fysiologi.
    Stadler, P.
    Sweedler, J. V.
    Tafer, H.
    Thomsen, B.
    Wali, R.
    Wang, J.
    White, S.
    Xu, X.
    Yerle, M.
    Zhang, G.
    Zhang, J.
    Zhao, S.
    Rogers, J.
    Churcher, C.
    Schook, L. B.
    Analyses of pig genomes provide insight into porcine demography and evolution2012Inngår i: Nature, ISSN 0028-0836, E-ISSN 1476-4687, Vol. 491, nr 7424, s. 393-398Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    For 10,000 years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars approximately 1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model.

  • 10.
    Hidalgo, Christian
    et al.
    Univ Andres Bello, Fac Ecol & Recursos Nat, Escuela Med Vet, Santiago, Chile..
    Pia Garcia, Maria
    Univ Andres Bello, Fac Ecol & Recursos Nat, Escuela Med Vet, Santiago, Chile..
    Stoore, Caroll
    Univ Andres Bello, Fac Ecol & Recursos Nat, Escuela Med Vet, Santiago, Chile..
    Pablo Ramirez, Juan
    Univ Andres Bello, Fac Ecol & Recursos Nat, Escuela Med Vet, Santiago, Chile..
    Monteiro, Karina Mariante
    Univ Fed Rio Grande Sul UFRGS, Lab Genom Estrutural & Func, Porto Alegre, RS, Brazil.;Univ Fed Rio Grande Sul UFRGS, Lab Biol Mol Cestodeos, Porto Alegre, RS, Brazil..
    Hellman, Ulf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Ludwiginstitutet för cancerforskning.
    Zaha, Arnaldo
    Univ Fed Rio Grande Sul UFRGS, Lab Genom Estrutural & Func, Porto Alegre, RS, Brazil.;Univ Fed Rio Grande Sul UFRGS, Lab Biol Mol Cestodeos, Porto Alegre, RS, Brazil..
    Ferreira, Henrique Bunselmeyer
    Univ Fed Rio Grande Sul UFRGS, Lab Genom Estrutural & Func, Porto Alegre, RS, Brazil.;Univ Fed Rio Grande Sul UFRGS, Lab Biol Mol Cestodeos, Porto Alegre, RS, Brazil..
    Galanti, Norbel
    Univ Chile, Fac Med, Inst Ciencias Biomed, Programa Biol Celular & Mol, Santiago 7, Chile..
    Landerer, Eduardo
    Univ Andres Bello, Fac Med, Escuela Med, Santiago, Chile..
    Paredes, Rodolfo
    Univ Andres Bello, Fac Ecol & Recursos Nat, Escuela Med Vet, Santiago, Chile..
    Proteomics analysis of Echinococcus granulosus protoscolex stage2016Inngår i: Veterinary parasitology, ISSN 0304-4017, E-ISSN 1873-2550, Vol. 218, s. 43-45Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Echinococcus granulosus protoscolex proteins were separated using two-dimensional electrophoresis and then identified using mass spectrometry; we identified 61 proteins, 28 which are newly described of which 4 could be involved in hydatid cyst fertility molecular mechanisms.

  • 11.
    Jäderkvist, Kim
    et al.
    Swedish Univ Agr Sci, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden.
    Holm, Niina
    Swedish Univ Agr Sci, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden.
    Imsland, Freyja
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi.
    Arnason, Thorvaldur
    IHBC AB, SE-74494 Morgongava, Sweden.
    Andersson, Leif
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi.
    Andersson, Lisa S.
    Swedish Univ Agr Sci, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden.
    Lindgren, Gabriella
    Swedish Univ Agr Sci, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden.
    The importance of the DMRT3 'Gait keeper' mutation on riding traits and gaits in Standardbred and Icelandic horses2015Inngår i: Livestock Science, ISSN 1871-1413, E-ISSN 1878-0490, Vol. 176, s. 33-39Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Previous studies have shown that a single base-pair mutation, a change from cytosine (C) to adenine (A), in the DMRT3 gene affects both the ability to show ambling and lateral gaits in a wide range of horse breeds, as well as racing performance and trotting technique in Standardbred and Nordic trotters. The variant allele is present in gaited breeds but is absent, or found at a very low frequency, in breeds used for Western-European style riding and flat racing, like the Swedish Warmblood and Thoroughbreds as well as in draught horses. This indicates that the variant allele might have a negative effect on certain riding performance traits in horses. Therefore, one aim of this study was to investigate whether the DMRT3 variant affects canter in Standardbred trotters, and to test if heterozygous horses (CA) were better suited for Western-European style riding than homozygous horses (M). Riding traits were studied in 115 Standardbred horses, and a similar study was also performed with data from 55 Nordic trotters. The results showed that CA Standardbreds had significantly better balance in canter, both collected and extended canter, than M horses. The CA horses also got significantly higher scores for transitions in collected canter. For the rhythm we found no significant differences between the genotypes. In the Nordic trotters we were unable to establish any significant difference for canter ability. Another aim of this study was to investigate the effect of the variant allele on riding abilities and gaits in the Icelandic horse (n=446). Practically all horse breeds considered to be three-gaited have a CC genotype, in contrast Icelandic CC horses can show tolt We therefore tested whether the variant influenced how difficult it was to initiate tolt training for these horses. It was also investigated whether the variant affects which gaits Icelandic horses choose, both at liberty and during initial training. Icelandic CC horses were significantly more difficult to train to tolt compared to CA and AA horses. The M Icelandic horses showed the lateral gaits tolt and pace significantly more frequent, both at liberty and during initial training, than CA or CC horses. The majority of the Icelandic CC and CA horses chose trot at liberty and during initial training.

  • 12.
    Kaasik, Allan
    Estonian University of Life Sciences, Tartu.
    41 Relationship between Livestock Nutrition and Excreted Nitrogen and Phosphorus Content2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 304-307Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 13.
    Leming, Ragnar
    Estonian University of Life Sciences, Tartu.
    39 Consumer Demands: Feeding in Organic Farming2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 284-287Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 14.
    Magnusson, Ulf
    Swedish University of Agricultural Sciences.
    21. Overview of Infectious Diseases and the Wildlife-Livestock Interface2012Inngår i: Ecology and Animal Health / [ed] Leif Norrgren and Jeffrey Levengood, Uppsala: Baltic University Press , 2012, 1, s. 183-185Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 15.
    Newberry, Ruth C.
    Washington State University Pullman, Washington.
    46 Contemporary Issues in Farm Animal Housing and Management: Poultry Well-being2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 338-343Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 16.
    Pettigrew, James E.
    et al.
    University of Illinois at Urbana-Champaign.
    Baker, Rodney B.
    North Carolina State University, Raleigh, NC, USA.
    27. Health Management with Reduced Use of Antibiotics in Pig Production2012Inngår i: Ecology and Animal Health / [ed] Leif Norrgren and Jeffrey Levengood, Uppsala: Baltic University Press , 2012, 1, s. 214-221Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 17.
    Redmalm, David
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Sociologiska institutionen. Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Biopolitik och husdjurssorg2017Inngår i: Fronesis, ISSN 1404-2614, nr 56-57, s. 147-159Artikkel i tidsskrift (Annet vitenskapelig)
  • 18. Redmalm, David
    Review of Humans, Animals and Biopolitics: The More-than-Human Condition, Edited by Kristin Asdal, Tone Druglitrö and Steve Hinchliffe2017Inngår i: Nordic Journal of Science and Technology Studies, ISSN 1894-4647, Vol. 5, nr 1, s. 38-39Artikkel, omtale (Annet vitenskapelig)
    Abstract [en]

    Michel Foucault’s concept of biopolitics captures the way a decentralized form of governing measures and mobilizes life itself through a number of technologies, such as demographics, surveillance and health initiatives, with the aim to prolong and enhance the lives of a population. According to Foucault, this biopolitical form of governing characteristic of modernity implies a detached and technical stance towards individual lives. In short, biopolitics turns individual lives into life as a mass noun. Interestingly, when human life is treated as a resource, human’s self-proclaimed position as the crown of creation is unsettled and humans find themselves part of the same biopolitical nexus as many other animals. The technologies and consequences of the biopolitization of humans and other animals is the subject of the volume Humans, Animals and Biopolitics, edited by Kristin Asdal, Tone Druglitrö and Steve Hinchliffe. It is a book that should be required reading for Foucauldian theorists and human-animal studies scholars alike.

  • 19. Redmalm, David
    Sharing the condition of abandonment: The beastly topology of condolence cards for bereaved pet owners2017Inngår i: Animal Places: Lively Cartographies of Human-Animal Relations / [ed] Jacob Bull, Tora Holmberg and Cecilia Åsberg, London and New York: Routledge, 2017, 1, s. 89-114Kapittel i bok, del av antologi (Fagfellevurdert)
    Abstract [en]

    This chapter focuses on spatiality in representations of the loss of and grief for companion animals. Giorgio Agamben’s theorization of the distinction between political and bare life is used to analyse around 350 condolence cards for bereaved pet owners. It is shown that the visual emplacement of pets in different contexts in the collection of cards underlines that pets are worth grieving, while at the same time a distance is maintained between humans and other animals. In spite of this distancing, it is argued that the cards have the potential to challenge the normative boundary between grievable and ungrievable life. 

  • 20.
    Ribó, Oriol
    et al.
    European Food Safety Authority (EFSA), Parma, Italy.
    Blokhuis, Harry
    Swedish University of Agricultural Sciences.
    51 Risk Assessment Methodology and Identification of Animal-based Indicators to Assess Animal Welfare at Farm Level2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 362-368Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 21.
    Roasto, Mati
    et al.
    Estonian University of Life Sciences, Tartu, Estonia.
    Hörman, Ari
    Estonian University of Life Sciences, Tartu, Estonia.
    Hänninen, Marja-Liisa
    University of Helsinki.
    26. Antimicrobial Resistance: a Food Safety Perspective2012Inngår i: Ecology and Animal Health / [ed] Leif Norrgren and Jeffrey Levengood, Uppsala: Baltic University Press , 2012, 2, s. 212-213Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 22.
    Roasto, Mati
    et al.
    Estonian University of Life Sciences, Tartu, Estonia.
    Hörman, Ari
    Finnish Defence Forces, Helsinki, Finland.
    Hänninen, Marja-Liisa
    University of Helsinki.
    34. Food-borne Pathogens and Public Health2012Inngår i: Ecology and Animal Health / [ed] Leif Norrgren and Jeffrey Levengood, Uppsala: Baltic University Press , 2012, 1, s. 271-282Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 23.
    Rollin, Bernard
    Colorado State University Fort Collins, Colorado, USA.
    50 An Opinion on the Role of Ethics in Modern Animal Production Systems2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 358-361Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 24.
    Surovtsev, Vladimir
    et al.
    North-West Research Institute of Economics and Organization of Agriculture St Petersburg – Pushkin, Russia.
    Nikulina, Julia
    North-West Research Institute of Economics and Organization of Agriculture St Petersburg – Pushkin, Russia.
    18 Environmental Effects of Cattle Rearing and Milk Production2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 142-145Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 25. Velie, Brandon D.
    et al.
    Jaederkvist, Kim
    Imsland, Freyja
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi.
    Viluma, Agnese
    Andersson, Lisa S.
    Mikko, Sofia
    Eriksson, Susanne
    Lindgren, Gabriella
    Frequencies of polymorphisms in myostatin vary in Icelandic horses according to the use of the horses2015Inngår i: Animal Genetics, ISSN 0268-9146, E-ISSN 1365-2052, Vol. 46, nr 4, s. 467-468Artikkel i tidsskrift (Fagfellevurdert)
  • 26.
    Viiralt, Rein
    et al.
    Estonian University of Life Sciences, Tartu.
    Selge, Are
    Estonian University of Life Sciences, Tartu.
    40 Producing High Quality Feed: Grassland Management2012Inngår i: Sustainable Agriculture / [ed] Christine Jakobsson, Uppsala: Baltic University Press , 2012, 1500, s. 288-303Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 27.
    Wierup, Martin
    Swedish University of Agricultural Sciences.
    25. Principles and Strategies for the Prevention and Control of Infectious Diseases in Livestock and Wildlife2012Inngår i: Ecology and Animal Health / [ed] Leif Norrgren and Jeffrey Levengood, Uppsala: Baltic University Press , 2012, 2, s. 203-211Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 28.
    Wierup, Martin
    et al.
    Swedish University of Agricultural Sciences.
    Bengtsson, Björn
    National Veterinary Institute, Uppsala, Sweden.
    28. Antimicrobial Resistance in Scandinavia after Termination of Antimicrobials for Growth Promotion2012Inngår i: Ecology and Animal Health / [ed] Leif Norrgren and Jeffrey Levengood, Uppsala: Baltic University Press , 2012, 2, s. 222-227Kapittel i bok, del av antologi (Annet (populærvitenskap, debatt, mm))
  • 29.
    Yusnizar, Y.
    et al.
    Bogor Agr Univ IPB, Grad Sch, Bogor 16680, Indonesia.;Swedish Univ Agr Sci SLU, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden.;Indonesian Inst Sci LIPI, Biotechnol Res Ctr, Cibinong 16912, Indonesia..
    Wilbe, Maria
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi, Medicinsk genetik och genomik. Swedish Univ Agr Sci SLU, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden..
    Herlino, A. O.
    Swedish Univ Agr Sci SLU, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden..
    Sumantri, C.
    Bogor Agr Univ IPB, Fac Anim Sci, Dept Anim Prod & Technol, Bogor 16680, Indonesia..
    Noor, R. Rachman
    Bogor Agr Univ IPB, Fac Anim Sci, Dept Anim Prod & Technol, Bogor 16680, Indonesia..
    Boediono, A.
    Bogor Agr Univ IPB, Fac Vet Med, Dept Anat Physiol & Pharmacol, Bogor 16680, Indonesia..
    Andersson, Leif
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi. Swedish Univ Agr Sci SLU, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden..
    Andersson, G.
    Swedish Univ Agr Sci SLU, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden..
    Microphthalmia-associated transcription factor mutations are associated with white-spotted coat color in swamp buffalo2015Inngår i: Animal Genetics, ISSN 0268-9146, E-ISSN 1365-2052, Vol. 46, nr 6, s. 676-682Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    A candidate gene analysis of the microphthalmia-associated transcription factor (MITF) gene was used in an attempt to identify the genetic basis for a white-spotted coat color phenotype in the Asian swamp buffalo (Bubalus bubalis carabanensis). Ninety-three buffaloes32 solid, 38 spotted and 23 white individualswere Sanger-sequenced for all MITF exons as well as highly conserved intronic and flanking regions. MITFcDNA representing skin and iris tissue from six spotted, nine solid and one white buffaloes was also Sanger-sequenced to confirm detected mutations. Two independent loss-of-function mutations, a premature stop codon (c.328C>T, p.Arg110*) and a donor splice-site mutation (c.840+2T>A, p.Glu281_Leu282Ins8), both of which cause white-spotted coat color in swamp buffaloes, were identified. The nonsense mutation leads to a premature stop codon in exon 3, and likely removal of the resulting mRNA via nonsense-mediated decay pathway, whereas the donor splice-site mutation leads to aberrant splicing of exon 8 that encodes part of a highly conserved region of MITF. The resulting insertion of eight amino acid residues is expected to perturb the leucine zipper part in the basic helix-loop-helix leucine zipper (bHLH-Zip) domain and will most likely influence dimerization and DNA binding capacity. Electrophoretic mobility shift assay was performed using mutant and wild-type MITF proteins and showed that the mutant MITF protein resulting from the splice-site mutation decreased invitro DNA binding capacity compared to wild-type MITF. White-spotted buffalo bulls are sacrificed in funeral ceremonies in Tana Toraja, Indonesia, because they are considered holy, and our results show that genetic variation causes a tie to the cultural use of these buffaloes.

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