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  • 101.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Blomgren, Lena
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Hansson, M
    Cost and reimbursement influence on treatment strategy: Is it ethical?2011In: Advances in venous therapy / [ed] Wittens C, Turin: Edizioni Minerva Medica , 2011Chapter in book (Refereed)
  • 102.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Clement, D.
    Adjudication of end points in studies on substances influencing haemostasis: an example from vascular surgery2008In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 36, no 6, p. 703-4Article in journal (Refereed)
  • 103.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Clement, D
    Unsuitability for vascular reconstruction from an adjudicators point of view2012In: International Journal of Angiology, ISSN 1061-1711, E-ISSN 1615-5939, Vol. 31, no 1, p. 90-91Article in journal (Refereed)
  • 104.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Ettles, Duncan
    Karacagil, Sadettin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Ljungman, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Löfberg, Anne-Marie
    Ulus, A. Tulga
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Is run-off percutaneous transluminal angioplasty worthwhile?2000In: Vascular and endovascular opportunities / [ed] Roger Malcolm Greenhalgh, J T Powell, Adam W M Mitchell, London: W.B. Saunders , 2000, 1:aChapter in book (Other academic)
  • 105.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Lindeman, Johannes H N
    Lindholt, Jes S
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Antimicrobial treatment to impair expansion of abdominal aortic aneurysm (AAA): a systematic review of the clinical evidence2013In: Current vascular pharmacology, ISSN 1875-6212, Vol. 11, no 3, p. 288-292Article, review/survey (Refereed)
    Abstract [en]

    Antimicrobial treatment to attenuate expansion of abdominal aortic aneurysm has been suggested, especially with the focus on Chlamydophila. In this systematic literature review only four randomized trials were identified. In two small studies there is an indication of an effect of roxithromycin. In conclusion, however, more studies are needed, and they must be properly sized based on power calculations as well as antimicrobially relevant. Such trials are on the way both in Europe and the US, the results being awaited with interest.

  • 106.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Mani, Kevin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Troëng, Thomas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Wanhainen, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Treatment of aortic aneurysms registered in Swedvasc: Development reflected in a national vascular registry with an almost 100% coverage2018In: Gefässchirurgie, ISSN 0948-7034, E-ISSN 1434-3932, Vol. 23, no 5, p. 340-345Article in journal (Refereed)
    Abstract [en]

    Swedvasc is a registry for vascular surgical procedures, both open and endovascular. It was started in 1987 and since 1994 the whole population of Sweden is covered, at present around 10 million inhabitants. In a recent external validation, it was found to be highly accurate with abdominal aortic aneurysm surgery correctly reported in > 96%. In this paper various factors explaining the almost 100% coverage are discussed, one important being that the registry has been developed and maintained within the profession of vascular surgery and not dictated by authorities. Another factor of importance is the possibility to use data in various research projects and so far 15 PhD theses have used Swedvasc data. To exemplify the practical use of the registry, the treatment of abdominal aortic aneurysms is scrutinized and among the various complications abdominal compartment syndrome is analyzed. Several significant temporal changes have been observed over the almost 25 years of Swedvasc: increasing use of endovascular surgery, treatment of aneurysms detected by screening , decreasing treatment for rupture, improved outcome, increasing treatment of older patients and patients with comorbid conditions. In conclusion, a high quality national vascular registry can be valid with high compliance and can be used to study population-based development of treatment and outcome. It can also be used to perform international comparisons with other registries, thereby getting an indication of the quality of care.

  • 107.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Mani, Kevin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Wanhainen, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Epidemiological aspects on abdominal aortic aneurysm (AAA)2010In: Pan Arab Angiology Journal, ISSN 2000-6535, Vol. 1, p. 1-Article in journal (Refereed)
    Abstract [en]

    In this overview, the present day knowledge on the epidemiology of abdominal aortic aneurysms (AAA) is summarized based on a review of the current literature. The prevalence of AAA and incidence of rupture is analyzed, and the natural history of the disease is illustrated both concerning the AAA as such and the survival of the patient. This knowledge is important when contemplating on screening for AAA, which is being implemented in several countries worldwide.

  • 108.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Rolandsson, Olof
    Säwe, Juliette
    SBU svarar på kritik: läs hela Alert-rapporten om fönstertittarsjuka2010In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 107, no 38, p. 2257-2257Article in journal (Refereed)
  • 109.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Rolandsson, Olov
    Sawe, J
    Cilostazol, a platelet inhibitor, in treating intermittent claudication: a systematic review2011Conference paper (Refereed)
  • 110.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Rosen, M.
    Health Technology Assessment in Surgery2012In: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267, Vol. 101, no 2, p. 132-137Article, review/survey (Refereed)
    Abstract [en]

    This review focuses on how surgical methods should be assessed from a health technology perspective. The use of randomized controlled trials, population based registries, systematic literature research and the recently published IDEAL method are briefly discussed.

  • 111.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Svensson, Peter J.
    Treatment of mesenteric vein thrombosis2010In: Seminars in Vascular Surgery, ISSN 0895-7967, E-ISSN 1558-4518, Vol. 23, no 1, p. 65-68Article in journal (Refereed)
    Abstract [en]

    Mesenteric vein thrombosis has a similar clinical course as arterial, although more prolonged. In the majority of cases conventional anticoagulant treatment should be used and is often successful. The duration should be at least 6 months. Thrombolysis has been used, both systemic and local, although only in small series. Surgery is indicated when there is peritonitis, when often bowel resection is necessary. Thrombectomy has been used infrequently.

  • 112.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Säwe, Juliette
    Wahlberg, Eric
    Benartärsjukdom: Inget nytt sedan SBU-rapporten2011In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 108, no 8, p. 403-405Article in journal (Refereed)
  • 113.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Wanhainen, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Cerebrospinal venös insufficiens som orsak till MS har svagt stöd. Inte rimligt att nu erbjuda ballongvidgande behandling: [Cerebrospinal venous insufficiency as a cause of MS weakly supported. Unreasonable to offer balloon dilatation therapy now].2011In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 108, no 39, p. 1899-1901Article in journal (Refereed)
    Abstract [en]

    Chronic cerebrospinal venous insufficiency (CCSVI) has been suggested as a hypothesis explaining the development of multiple sclerosis (MS). In case reports, balloon dilatation of obstructed venous outflow has been successful and enthusiastic patient histories have given hope to MS patients. A systematic review of the evidence behind the pathophysiological hypothesis as well as concerning balloon dilatation does not support this form of treatment outside well designed trials.

  • 114.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Wanhainen, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Konsten att skriva ett vetenskapligt manus2015In: Svensk Kirurgi, ISSN 0346-847X, Vol. 73, no 1, p. 10-12Article in journal (Other academic)
  • 115.
    Bergqvist, David
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Wiklund, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
    [Caution for prophylaxis of thrombosis in connection with spinalanesthesia. Risk of hemorrhage when low-molecular-weight heparin isadministered in epidural/spinal anesthesia]2000In: Lakartidningen, Vol. 97Article in journal (Other academic)
  • 116.
    Bernhoff, Karin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Patients’ experiences of life years after severe civilian lower extremity trauma with vascular injuryManuscript (preprint) (Other academic)
  • 117.
    Bernhoff, Karin
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Iatrogenic popliteal artery injury in non arthroplasty knee surgery2015In: The Bone & Joint Journal, ISSN 2049-4394, E-ISSN 2049-4408, Vol. 97B, no 2, p. 192-196Article in journal (Refereed)
    Abstract [en]

    We have investigated iatrogenic popliteal artery injuries (PAI) during non arthroplasty knee surgery regarding mechanism of injury, treatment and outcomes, and to identify successful strategies when injury occurs. In all, 21 iatrogenic popliteal artery injuries in 21 patients during knee surgery other than knee arthroplasty were identified from the Swedish Vascular Registry (Swedvasc) between 1987 and 2011. Prospective registry data were supplemented with case-records, including long-term follow-up. In total, 13 patients suffered PAI during elective surgery and eight during urgent surgery such as fracture fixation or tumour resection. Nine injuries were detected intraoperatively, five within 12 to 48 hours and seven > 48 hours post-operatively (two days to 23 years). There were 19 open vascular and two endovascular surgical repairs. Two patients died within six months of surgery. One patient required amputation. Only six patients had a complete recovery of whom had the vascular injury detected at time of injury and repaired by a vascular surgeon. Patients sustaining vascular injury during elective procedures are more likely to litigate (p = 0.029). We conclude that outcomes are poorer when there is a delay of diagnosis and treatment, and that orthopaedic surgeons should develop strategies to detect PAI early and ensure rapid access to vascular surgical support.

  • 118.
    Bernhoff, Karin
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Larsson, Jan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Health Services Research.
    Jangland, Eva
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences.
    Patient Experiences of Life Years After Severe Civilian Lower Extremity Trauma With Vascular Injury2016In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 52, no 5, p. 690-695Article in journal (Refereed)
    Abstract [en]

    OBJECTIVE: Severe lower limb trauma with arterial injury is often devastating for the individual. Many studies describe how to manage these injuries when they occur. Short-term functional outcome is quite well described, but the patients are often young, and their suffering is physical, mental, and social from a lifelong perspective. The aim of this study was to report patient experiences of their lives several years after their accidents, and to explore mechanisms of how to improve management.

    METHOD: The Swedvasc registry was searched for participants from 1987 to 2011, living in the region of Uppsala, Sweden. Some amputated participants were added from the Walking Rehabilitation Center. There were five reconstructed patients with an intact limb, and three with amputations. In depth interviews were conducted and systematically analyzed, using A Giorgi's descriptive phenomenological method.

    RESULTS: Eight patients participated, five with reconstructed and three with amputated limbs. Life affecting functional impairments were described by all patients. The patients undergoing amputation had received more structured follow up and support through the Walking Rehabilitation Center. The satisfaction with the cosmetic result was poorer than expected. All patients had developed strategies of how to cope with their impairments and stated they now lived "normal lives."

    CONCLUSIONS: Despite substantial physical, psychological, and cosmetic impairments years after severe lower limb trauma, the participants described life as "normal" and mainly satisfactory. Transition to the new situation could have been facilitated by more frequent and continuous follow up after discharge from hospital, in particular among the non-amputated patients who tend to be lost to follow up. Findings also indicate that family members have to be acknowledged, strengthened, and supported.

  • 119.
    Bernhoff, Karin
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
    Rudström, Håkan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Gedeborg, Rolf
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Popliteal artery injury in knee arthroplasty: a population based, nationwide study2013In: Journal of Bone and Joint Surgery, ISSN 0301-620X, E-ISSN 2044-5377, Vol. 95, no 12, p. 1645-1649Article in journal (Other academic)
    Abstract [en]

    Popliteal artery injury (PAI) is a feared but rare complication during knee arthroplasty (KA). The aim was to study PAI during KA: Type of injury, treatment and outcome.

    Thirty-two cases were identified in the national Swedish vascular registry (Swedvasc) and the Swedish Patient Insurance databases. Prospective data from the registries was supplemented with case-records, including long-term follow-up.

    Twenty-five injuries (78%) were due to penetrating, seven to blunt trauma. Three different presentations of injury were identified: Bleeding (n=14), ischaemia (n=7) and false aneurysm formation (n=11). Five (16%) cases were during revision KA. Twelve injuries (38%) were detected intraoperatively, eight (25%) within 24 hours (range 3-24) and twelve (38%) >24 hours postoperatively (range 2-90), 28 (88%) were treated with open surgery. Patency at 30 days was 97% (one amputation). Twenty-five (78%) patients had residual symptoms at the end of follow-up (median 546 days, range: 24-1251). Six of the seven patients with complete recovery had an early diagnosis of the PAI during the procedure, and were treated by a vascular surgeon in the same hospital.

    Outcome after popliteal artery injury during KA is often negatively affected by diagnostic and therapeutic delay. Bleeding and pseudoaneurysm were the most common clinical presentations.

  • 120. Berntorp, E
    et al.
    Astermark, J
    Baghaei, F
    Bergqvist, David
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Holmström, M
    Ljungberg, B
    Norlund, A
    Palmblad, J
    Petrini, P
    Stigendal, L
    Säwe, J
    Treatment of haemophilia A and B and von Willebrand's disease: summary and conclusions of a systematic review as part of a Swedish health-technology assessment2012In: Haemophilia, ISSN 1351-8216, E-ISSN 1365-2516, Vol. 18, no 2, p. 158-165Article, review/survey (Refereed)
    Abstract [en]

    In an ongoing health-technology assessment of haemophilia treatment in Sweden, performed by the governmental agency Dental and Pharmaceutical Benefits Agency (TLV; tandvårds-och läkemedelsförmånsverket), the Swedish Council on Health Technology Assessment (SBU; statens beredning för medicinsk utvärdering) was called upon to evaluate treatment of haemophilia A and B and von Willebrand's disease (VWD) with clotting factor concentrates. To evaluate the following questions: What are the short-term and long-term effects of different treatment strategies? What methods are available to treat haemophilia patients that have developed inhibitors against factor concentrates? Based on the questions addressed by the project, a systematic database search was conducted in PubMed, NHSEED, Cochrane Library, EMBASE and other relevant databases. The literature search covered all studies in the field published from 1985 up to the spring of 2010. In most instances, the scientific evidence is insufficient for the questions raised in the review. Concentrates of coagulation factors have good haemostatic effects on acute bleeding and surgical intervention in haemophilia A and B and VWD, but conclusions cannot be drawn about possible differences in the effects of different dosing strategies for acute bleeding and surgery. Prophylaxis initiated at a young age can prevent future joint damage in persons with haemophilia. The available treatment options for inhibitors have been insufficiently assessed. The economic consequences of various treatment regimens have been insufficiently analysed. Introduction of national and international registries is important.

  • 121.
    Biglarnia, Alireza
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Transplantation Surgery.
    Bergqvist, David
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Johansson, Maria
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Upper Abdominal Surgery.
    Wadström, Jonas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Transplantation Surgery.
    Venous thromboembolism in live kidney donors: a prospective study2008In: Transplantation, ISSN 0041-1337, E-ISSN 1534-6080, Vol. 86, no 5, p. 659-661Article in journal (Refereed)
    Abstract [en]

    AIM:

    The aim of this study was to evaluate risk factors for venous thromboembolism (VTE) and deep vein thrombosis after living donor nephrectomy in a center using extensive preoperative screening and perioperative venous duplex scan.

    MATERIAL AND METHODS:

    Thrombophilia screening and pre- and postoperative ultrasonographies were performed in 130 consecutive living kidney donors (laparoscopic 105, open 25). Donors were followed prospectively for at least 3 months. All donors received prophylaxis with the low molecular weight heparin enoxaparin and compression stockings. Donors with increased risk received a double dose of enoxaparin and the prophylaxis was continued for 6 weeks. Donors with venous thrombosis at discharge duplex also received prolonged prophylaxis.

    RESULTS:

    The frequency of thrombophilia was similar to what can be expected in the Swedish population (four with factor V Leiden and one each with protein S deficiency, prothrombin gene mutation, and anticardiolipin antibodies). Preoperative duplex was normal. Three donors had small postoperative deep vein thrombosis. Twelve donors (9.2%) received an intensified and prolonged prophylaxis. No further thromboembolic complications developed in 3 postoperative months.

    CONCLUSION:

    With the present protocol for preoperative evaluation, perioperative duplex screening, and prophylaxis, the risk of postoperative VTE is low after living donor nephrectomy. Given that 9.2% had risk factors or developed deep vein thrombosis, the extraordinary situation of an operation being performed on a healthy person who has no therapeutic benefit and the low incidence of VTE in the present study, we recommend the presented approach to be implemented more broadly and that further studies are performed in larger cohorts.

  • 122. Bjarnason, Thordur
    et al.
    Montgomery, A.
    Ekberg, O.
    Acosta, S.
    Svensson, M.
    Wanhainen, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Petersson, U.
    One-Year Follow-up After Open Abdomen Therapy With Vacuum-Assisted Wound Closure and Mesh-Mediated Fascial Traction2013In: World Journal of Surgery, ISSN 0364-2313, E-ISSN 1432-2323, Vol. 37, no 9, p. 2031-2038Article in journal (Refereed)
    Abstract [en]

    Open abdomen (OA) therapy frequently results in a giant planned ventral hernia. Vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM) enables delayed primary fascial closure in most patients, even after prolonged OA treatment. Our aim was to study the incidence of hernia and abdominal wall discomfort 1 year after abdominal closure. A prospective multicenter cohort study of 111 patients undergoing OA/VAWCM was performed during 2006-2009. Surviving patients underwent clinical examination, computed tomography (CT), and chart review at 1 year. Incisional and parastomal hernias and abdominal wall symptoms were noted. The median age for the 70 surviving patients was 68 years, 77 % of whom were male. Indications for OA were visceral pathology (n = 40), vascular pathology (n = 22), or trauma (n = 8). Median length of OA therapy was 14 days. Among 64 survivors who had delayed primary fascial closure, 23 (36 %) had a clinically detectable hernia and another 19 (30 %) had hernias that were detected on CT (n = 18) or at laparotomy (n = 1). Symptomatic hernias were found in 14 (22 %), 7 of them underwent repair. The median hernia widths in symptomatic and asymptomatic patients were 7.3 and 4.8 cm, respectively (p = 0.031) with median areas of 81.0 and 42.9 cm(2), respectively (p = 0.025). Of 31 patients with a stoma, 18 (58 %) had a parastomal hernia. Parastomal hernia (odds ratio 8.9; 95 % confidence interval 1.2-68.8) was the only independent factor associated with an incisional hernia. Incisional hernia incidence 1 year after OA therapy with VAWCM was high. Most hernias were small and asymptomatic, unlike the giant planned ventral hernias of the past.

  • 123.
    Bjorck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Surgery for ruptured abdominal aortic aneurysm: trial reports comparable short term survival after open or endovascular repair2014In: BMJ. British Medical Journal, E-ISSN 1756-1833, Vol. 348, p. g95-Article in journal (Other academic)
  • 124.
    Björck, M
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences.
    Bergqvist, D
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences.
    Eliasson, K
    Jansson, I
    Karlström, L
    Kragsterman, B
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences.
    Lundell, A
    Malmstedt, J
    Nordanstig, J
    Norgren, L
    Troëng, T
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences. Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Twenty years with the Swedvasc Registry.2008In: Eur J Vasc Endovasc Surg, ISSN 1532-2165, Vol. 35, no 2, p. 129-30Article in journal (Refereed)
  • 125.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Abdominal Compartment Syndrome Post EVAR: New Therapies Are Keenly Needed, but is tPA-Assisted Hematoma Evacuation the Answer?2012In: Journal of Endovascular Therapy, ISSN 1526-6028, E-ISSN 1545-1550, Vol. 19, no 2, p. 149-150Article in journal (Other academic)
  • 126.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Akut och kronisk ischemi2016In: Kirurgi / [ed] Bengt Jeppsson, Olle Ljungqvist, Peter Naredi, Malin Sund, Studentlitteratur AB, 2016, 4, p. 575-596Chapter in book (Refereed)
  • 127.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Akut och kronisk ischemi2010In: Kirurgi / [ed] Bengt Jeppson, Peter Naredi, Jörgen Nordenström, Bo Risberg, Lund: Studentlitteratur , 2010, 3, p. 683-707Chapter in book (Other academic)
  • 128.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Allt fler får akut tarmischemi: snabb diagnos och behandling räddar liv2012In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 109, no 49-50, p. 2284-2286Article in journal (Refereed)
    Abstract [en]

    This paper summarizes the epidemiology and diagnostic work-up of acute bowel ischaemia (ABI). Different etiologies are described: Arterial and venous, occlusive and non-occlusive hypoperfusion syndromes. All conditions, in particular embolus to the superior mesenteric artery, are more prevalent in older age-groups, explaining why the incidence is increasing over time, a result of demographic change. D-dimer is a readily available biomarker at most emergency wards working excellent as an exclusion test. A specific biomarker for intestinal ischaemia is not yet available. A break-through in diagnosing ABI is modern multi-detector CT-scan (MDCT), explaining why more patients are identified prior to irreversible bowel gangrene, and revascularized. It is important that the surgeon or physician communicates the clinical suspicion of ABI to the radiologist. An important part of the decision-making is if the MDCT should be performed in a patient with an elevated creatinin level, a common finding due to vomiting and hypovolaemia.

  • 129.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Can we learn anything from the dinosaurs?2019In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 57, no 3, p. 399-399Article in journal (Other academic)
  • 130.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Can we reduce the rate and severity of colonic ischemia following AAA-repair?2011In: Controversies and Updates in Vascular Surgery 2011 / [ed] JP Becquemin, Torino, Italy: Minerva Medica Eidtions , 2011, p. 233-242Chapter in book (Refereed)
  • 131.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Commentary on 'A Decision Aid Regarding Treatment Options for Patients with an Asymptomatic Abdominal Aortic Aneurysm: A Randomised Clinical Trial'2014In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 48, no 3, p. 284-284Article in journal (Other academic)
  • 132.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Commentary on 'Is Hypovitaminosis D Associated with Abdominal Aortic Aneurysm, and is there a Dose Response Relationship?'2013In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 45, no 6, p. 665-665Article in journal (Other academic)
  • 133.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Comments Regarding "Results from Craniocaudal Carotid Body Tumor Resection; Should It be the Standard Surgical Approach?"2013In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 46, no 6, p. 630-630Article in journal (Other academic)
  • 134.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Endotension After Bypass for Popliteal Aneurysm2015In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 49, no 4, p. 411-411Article in journal (Other academic)
  • 135.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Endovascular or open repair for ruptured abdominal aortic aneurysm?2017In: BMJ. British Medical Journal, E-ISSN 1756-1833, Vol. 359, article id j5170Article in journal (Other academic)
  • 136.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Goda resultat av ny metod för behandling med öppen buk2013In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 1013, no 21, p. 110-110Article in journal (Other academic)
    Abstract [sv]

    Den gamla kirurgiska sanningen att man alltid bör stänga buken efter en laparotomi har ifrågasatts på senare år. Behandling med öppen buk är livräddande i flera situationer: vid skademinimering (damage control) efter trauma, septisk buk, akut pankreatit, brännskador, kärlkatastrofer och särskilt då ett bukkompartmentsyndrom hotar eller redan har utvecklats. 

    Denna behandling är dock inte riskfri. Utveckling av enteriska fistlar är särskilt fruktad, och efter lång tids behandling kan det vara svårt att stänga buken, vilket resulterar i stora och svårbehandlade bukväggsbråck. Båda dessa komplikationer är starkt associerade med lång behandlingstid med öppen buk.

    I en artikel publicerad i British Journal of Surgery rapporteras från Helsingfors universitetssjukhus (Meiland) goda resultat med en metod som kombinerar undertrycksbehandling med fasciatraktion med nät för att förhindra lateralisering av bukväggen. När man jämför behandling av 50 patienter med denna nyligen beskrivna metod [World J Surg. 2007;98:2133-7] med 54 kontroller som behandlades strax innan den nya metoden infördes är skillnaderna påtagliga. Andelen där man har kunnat stänga buken med fördröjd primär fasciasutur ökade från 44 till 78 procent (P > 0,001) och bland överlevarna från 59 till 93 procent.

    Metoden utvecklades i Malmö och Uppsala. I en multicenterstudie där även Falun och Gävle deltog [Br J Surg. 2011;98:735-43], där 111 patienter som krävde behandling med öppen buk i mer än fem dygn studerades, rapporterades liknande resultat: 89 procent fördröjd primär fasciasutur bland överlevarna. Även Trondheim har rapporterat goda resultat [Eur J Vasc Endovasc Surg. 2010;40:60-4]. 

    Det är glädjande att våra nordiska grannar har kunnat reproducera för patienterna så goda resultat, helt oberoende av den svenska gruppen. Metoden verkar sprida sig även globalt; den svenska multicenterstudien är den näst mest citerade artikeln i British Journal of Surgery 2011–2012.

    Potentiella bindningar eller jävsförhållanden: Referenten har varit med om att utveckla den metod som utvärderats.

  • 137.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Invited commentary2008In: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267, Vol. 97, no 2, p. 153-153Article in journal (Other academic)
  • 138.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Kommentar: Screening för bukaortaaneurysm effektiv och evidensbaserad medicinsk åtgärd2013In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 110, no 25-26, p. 1228-1229Article in journal (Other academic)
    Abstract [sv]

    Distriktsläkare Niklas Högerås ifrågasätter den ultraljudsscreening som drygt 90 procent av alla svenska 65-åriga män numera inbjuds till för att upptäcka och behandla bukaortaaneurysm. Jag är den förste att bejaka debatt och ifrågasättande, särskilt av screening, då man riskerar att skada individer som känt sig friska före undersökningen. Tyvärr innehåller Högerås text flera felaktiga påståenden, och behöver därför kommenteras.

  • 139.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Management of the tense abdomen or difficult abdominal closure after operation for ruptured abdominal aortic aneurysms2012In: Seminars in Vascular Surgery, ISSN 0895-7967, E-ISSN 1558-4518, Vol. 25, no 1, p. 35-38Article in journal (Refereed)
    Abstract [en]

    Increased intra-abdominal pressure (IAP) and abdominal compartment syndrome (ACS) are important clinical problems after repair of ruptured abdominal aortic aneurysms and are reviewed here. IAP >20 mm Hg occurs in approximately 50% of patients treated with open abdominal aortic aneurysm repair after rupture, and approximately 20% develop organ failure or dysfunction, fulfilling the criteria for ACS. Patients selected for endovascular aneurysm repair are often more hemodynamically stable, perhaps related to not handling the viscera or more favorable anatomy, resulting in less bleeding and, consequently, decreased risk of developing ACS. Centers that treat most patients with endovascular aneurysm repair tend to have the same proportion of ACS as after open repair. There are no randomized data on these aspects. Early nonsurgical therapy can prevent development of ACS. Medical therapy includes neuromuscular blockade and the combination of positive end-expiratory pressure, albumin, and furosemide. This proactive strategy can reduce the number of decompressive laparotomies, an important detail because treatment of ACS with open abdomen is a morbid procedure. When treatment with an open abdomen is necessary, it is important to choose a temporary abdominal closure that maintains sterile conditions during often prolonged treatment. In addition, it should prevent lateralization of the bowel wall and adhesions between the intestines and the bowel wall. Enteroatmospheric fistulae must be prevented. Many alternative methods have been suggested, but we prefer the combination of vacuum-assisted wound closure with mesh-mediated traction, which will be described.

  • 140.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Mesenteric vascular disease: problems and progress. Introduction2010In: Seminars in Vascular Surgery, ISSN 0895-7967, E-ISSN 1558-4518, Vol. 23, no 1, p. 1-3Article in journal (Refereed)
  • 141.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    More Light on Isolated Mesenteric Artery Dissection from the Countries of the Rising Sun2019In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 58, no 3, p. 400-400Article in journal (Other academic)
  • 142.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Part One: For the Motion. An Endovascular First Strategy is the Optimal Approach for Treating Acute Mesenteric Ischemia.2015In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 50, no 3, p. 273-280Article in journal (Refereed)
  • 143.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Regional variation in the incidence of abdominal aortic aneurysm in Sweden ( Br J Surg 2012; 99: 647–653)2012In: British Journal of Surgery, ISSN 0007-1323, E-ISSN 1365-2168, Vol. 99, no 5, p. 654-654Article in journal (Refereed)
  • 144.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Studying Colonic Ischaemia after Aortic Surgery Using Claims Data - An Intelligent Study Design and Low Hanging Fruit2018In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 56, no 4, p. 514-514Article in journal (Other academic)
  • 145.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Surgery for ruptured abdominal aortic aneurysm.2014In: BMJ (Clinical research ed.), ISSN 1756-1833, Vol. 348, p. g95-Article in journal (Refereed)
  • 146.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    The abdominal compartment syndrome: Way to manage patients with an open abdomen. Review article2008In: Sri Lanka Journal of Surgery, ISSN 0379-8240, Vol. 26, p. 27-33Article in journal (Refereed)
  • 147.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    The Fall of a Giant Professor: Nicolai Leontyevich Volodos May 15, 1934-April 3, 2016 OBITUARY2016In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 52, no 1, p. 3-4Article in journal (Refereed)
  • 148.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    The RESCAN Study Creates More Questions than Answers2013In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 46, no 2, p. 173-Article in journal (Refereed)
  • 149.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    The role of international bench-marking to improve outcome in treatment of ruptured abdominal aortic aneurysm.2014In: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. march 15, no 383, p. 933-934Article in journal (Refereed)
  • 150.
    Björck, Martin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
    Utbildning i den nya specialiteten kärlkirurgi2011In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 108, no 8, p. 415-417Article in journal (Refereed)
1234567 101 - 150 of 557
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