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  • 101. Vogiatzis, I
    et al.
    Marvisi, M
    Coole, J
    Gasparani, S
    Antoniou, K
    Ställberg, B
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine.
    Bjerg, A
    Herth, F
    Clini, E
    Clinical highlights: messages from Munich: ERJ Open Res May 15, 20152015In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 1, no 1Article in journal (Refereed)
  • 102.
    Wallström, Linda
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Research group (Dept. of women´s and children´s health), Perinatal, Neonatal and Pediatric Cardiology Research.
    Veneroni, Chiara
    Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy.
    Zannin, Emanuella
    Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy.
    Dellacà, Raffaele
    Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy.
    Sindelar, Richard
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Research group (Dept. of women´s and children´s health), Perinatal, Neonatal and Pediatric Cardiology Research.
    Forced oscillation technique for optimising PEEP in ventilated extremely preterm infants2020In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003Article in journal (Refereed)
  • 103.
    Wang, Juan
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
    Pindus, Mihkel
    Univ Tartu, Inst Family Med & Publ Hlth, Tartu, Estonia.
    Janson, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
    Sigsgaard, Torben
    Aarhus Univ, Danish Ramazzini Ctr, Sect Environm Occupat & Hlth, Dept Publ Hlth, Aarhus, Denmark.
    Kim, Jeong-Lim
    Gothenburg Univ, Occupat & Environm Med, Gothenburg, Sweden.
    Holm, Mathias
    Gothenburg Univ, Occupat & Environm Med, Gothenburg, Sweden.
    Sommar, Johan
    Umea Univ, Dept Publ Hlth & Clin Med, OCcupat & Environm Med, Umea, Sweden.
    Orru, Hans
    Univ Tartu, Inst Family Med & Publ Hlth, Tartu, Estonia;Umea Univ, Dept Publ Hlth & Clin Med, OCcupat & Environm Med, Umea, Sweden.
    Gislason, Thorarinn
    Landspitali Univ Hosp E7, Reykjavik, Iceland.
    Johannessen, Ane
    Univ Bergen, Ctr Int Hlth, Dept Global Publ Hlth & Primary Care, Bergen, Norway;Haukeland Hosp, Dept Occupat Med, Bergen, Norway.
    Bertelsen, Randi J.
    Univ Bergen, Ctr Int Hlth, Dept Global Publ Hlth & Primary Care, Bergen, Norway;Haukeland Hosp, Dept Occupat Med, Bergen, Norway;Univ Bergen, Dept Clin Sci, Bergen, Norway.
    Norbäck, Dan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
    Dampness, mould, onset and remission of adult respiratory symptoms, asthma and rhinitis2019In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 53, no 5, article id 1801921Article in journal (Refereed)
    Abstract [en]

    Study question: Is dampness and indoor mould associated with onset and remission of respiratory symptoms, asthma and rhinitis among adults?

    Materials and methods: Associations between dampness, mould and mould odour at home and at work and respiratory health were investigated in a cohort of 11 506 adults from Iceland, Norway, Sweden, Denmark and Estonia. They answered a questionnaire at baseline and 10 years later, with questions on respiratory health, home and work environment.

    Results: Baseline water damage, floor dampness, mould and mould odour at home were associated with onset of respiratory symptoms and asthma (OR 1.23-2.24). Dampness at home during follow-up was associated with onset of respiratory symptoms, asthma and rhinitis (OR 1.21-1.52). Dampness at work during follow-up was associated with onset of respiratory symptoms, asthma and rhinitis (OR 1.31-1.50). Combined dampness at home and at work increased the risk of onset of respiratory symptoms and rhinitis. Dampness and mould at home and at work decreased remission of respiratory symptoms and rhinitis.

    The answer to the question: Dampness and mould at home and at work can increase onset of respiratory symptoms, asthma and rhinitis, and decrease remission.

  • 104.
    Westerdahl, Elisabeth
    et al.
    Orebro Univ, Orebro Univ Hosp, Dept Physiotherapy, CAMTO, Orebro, Sweden;Orebro Univ, Fac Med & Hlth, Orebro, Sweden.
    Arne, Mats
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research. Ctr Clin Res, Karlstad, Sweden.
    Larsson, Matz
    Orebro Univ Hosp, Heart Lung Clin, Orebro, Sweden;Orebro Cty Council, Tobacco Prevent Unit, Orebro, Sweden.
    Engman, Kjell Ola
    Sormland Cty Council, Nykoping, Sweden.
    Spirometry to motivate smoking cessation - a systematic review2018In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 52Article in journal (Other academic)
  • 105.
    Wilkinson, Tom
    et al.
    Southampton Univ, Fac Med, Southampton, Hants, England.
    Schembri, Stuart
    Univ Dundee, Scottish Ctr Resp Res, Dundee, Scotland.
    Brightling, Christopher
    Univ Leicester, Inst Lung Hlth, Leicester, Leics, England.
    Bakerly, Nawar Diar
    Salford Royal NHS Fdn Trust, Salford, Lancs, England.
    Macnee, William
    Univ Edinburgh, Edinburgh, Midlothian, Scotland.
    Rombo, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centrum för klinisk forskning i Sörmland (CKFD).
    Hedner, Jan
    Sahlgrens Univ Hosp, Gothenburg, Sweden.
    Allen, Martin
    Univ Hosp North Midlands NHS Trust, Stoke On Trent, Staffs, England.
    Walker, Paul
    Aintree Univ Hosp NHS Fdn Trust, Liverpool, Merseyside, England.
    De Ryck, Iris
    GSK, Siena, Italy.
    Tasciotti, Annaelisa
    GSK, Siena, Italy.
    Casula, Daniela
    GSK, Siena, Italy.
    Testa, Marco
    GSK, Siena, Italy.
    Arora, Ashwani Kumar
    GSK, Siena, Italy.
    Late Breaking Abstract - Safety and immunogenicity of non-typeable H. influenzae (NTHi) adjuvanted vaccine in older adults with chronic obstructive pulmonary disease (COPD)2018In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 52Article in journal (Other academic)
  • 106. Ziegler-Heitbrock, Loems
    et al.
    Frankenberger, Marion
    Heimbeck, Irene
    Burggraf, Dorothe
    Wjst, Matthias
    Haeussinger, Karl
    Brightling, Chris
    Gupta, Sumit
    Parr, David
    Subramanian, Deepak
    Singh, Dave
    Kolsum, Umme
    Boschetto, Piera
    Potena, Alfredo
    Gorecka, Dorota
    Nowinski, Adam
    Barta, Imre
    Doeme, Balazs
    Strausz, Janos
    Greulich, Timm
    Vogelmeier, Claus
    Bals, Robert
    Hohlfeld, Jens M.
    Welte, Tobias
    Venge, Per
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
    Gut, Ivo
    Boland, Anne
    Olaso, Robert
    Hager, Joerg
    Hiemstra, Pieter
    Rabe, Klaus F.
    Unmuessig, Martina
    Mueller-Ouernhelm, Joachim
    Prasse, Antje
    The EvA study: aims and strategy2012In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 40, no 4, p. 823-829Article in journal (Refereed)
    Abstract [en]

    The EvA study is a European Union-funded project under the Seventh Framework Programme (FP7), which aims at defining new markers for chronic obstructive pulmonary disease (COPD) and its subtypes. The acronym is derived from emphysema versus airway disease, indicating that the project targets these two main phenotypes of the disease. The EvA study is based on the concept that emphysema and airway disease are governed by different pathophysiological processes, are driven by different genes and have differential gene expression in the lung. To define these genes, patients and non-COPD controls are recruited for clinical examination, lung function analysis and computed tomography (CT) of the lung. CT scans are used to define the phenotypes based on lung density and airway wall thickness. This is followed by bronchoscopy in order to obtain samples from the airways and the alveoli. These tissue samples, along with blood samples, are then subjected to genome-wide expression and association analysis and markers linked to the phenotypes are identified. The population of the EvA study is different from other COPD study populations, since patients with current oral glucocorticoids, antibiotics and exacerbations or current smokers are excluded, such that the signals detected in the molecular analysis are due to the distinct inflammatory process of emphysema and airway disease in COPD.

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